Lung squamous cell carcinoma_LUSC_TCGA-60-2696-01A-01R-0851-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

406 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-60-2696-01A-01R-0851-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
AARSD1 alanyl-tRNA synthetase domain containing 1
ABHD17C abhydrolase domain containing 17C
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACBD5 acyl-CoA binding domain containing 5
ACTR3C ARP3 actin-related protein 3 homolog C (yeast)
ACY1 aminoacylase 1
ADAM10 ADAM metallopeptidase domain 10
ADAMTSL5 ADAMTS-like 5
ADAT2 adenosine deaminase, tRNA-specific 2
AEN apoptosis enhancing nuclease
AGFG1 ArfGAP with FG repeats 1
AGTRAP angiotensin II receptor-associated protein
AIG1 androgen-induced 1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALPL alkaline phosphatase, liver/bone/kidney
AMDHD2 amidohydrolase domain containing 2
ANAPC5 anaphase promoting complex subunit 5
ANKDD1A ankyrin repeat and death domain containing 1A
ANXA11 annexin A11
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
APOBEC3D apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
AQR aquarius intron-binding spliceosomal factor
ARHGAP32 Rho GTPase activating protein 32
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ASB13 ankyrin repeat and SOCS box containing 13
ASPHD1 aspartate beta-hydroxylase domain containing 1
ASS1 argininosuccinate synthase 1
AVPI1 arginine vasopressin-induced 1
BCAR3 breast cancer anti-estrogen resistance 3
BCO2 beta-carotene oxygenase 2
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
BDKRB2 bradykinin receptor B2
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
BPGM 2,3-bisphosphoglycerate mutase
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BTBD1 BTB (POZ) domain containing 1
C10ORF12 chromosome 10 open reading frame 12
C10ORF55 chromosome 10 open reading frame 55
C11ORF65 chromosome 11 open reading frame 65
C14ORF79 chromosome 14 open reading frame 79
C15ORF48 chromosome 15 open reading frame 48
C15ORF61 chromosome 15 open reading frame 61
C8ORF74 chromosome 8 open reading frame 74
CA12 carbonic anhydrase XII
CAPN14 calpain 14
CARD10 caspase recruitment domain family, member 10
CASC4 cancer susceptibility candidate 4
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CATSPER2P1 cation channel, sperm associated 2 pseudogene 1
CCBL2 cysteine conjugate-beta lyase 2
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CCNDBP1 cyclin D-type binding-protein 1
CCPG1 cell cycle progression 1
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDNF cerebral dopamine neurotrophic factor
CDYL2 chromodomain protein, Y-like 2
CIRH1A cirrhosis, autosomal recessive 1A (cirhin)
CKMT1A creatine kinase, mitochondrial 1A
CLCN7 chloride channel, voltage-sensitive 7
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLMN calmin (calponin-like, transmembrane)
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CNTNAP4 contactin associated protein-like 4
COA7 cytochrome c oxidase assembly factor 7 (putative)
COBLL1 cordon-bleu WH2 repeat protein-like 1
COMMD4 COMM domain containing 4
COPS2 COP9 signalosome subunit 2
COQ9 coenzyme Q9
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CPEB3 cytoplasmic polyadenylation element binding protein 3
CPNE7 copine VII
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTAGE5 CTAGE family, member 5
CTSA cathepsin A
CUEDC1 CUE domain containing 1
CYB5B cytochrome b5 type B (outer mitochondrial membrane)
CYB5R1 cytochrome b5 reductase 1
CYFIP1 cytoplasmic FMR1 interacting protein 1
DAAM1 dishevelled associated activator of morphogenesis 1
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
DENND2C DENN/MADD domain containing 2C
DHDDS dehydrodolichyl diphosphate synthase
DHODH dihydroorotate dehydrogenase (quinone)
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNASE1L1 deoxyribonuclease I-like 1
DPH6 diphthamine biosynthesis 6
DSCR3 Down syndrome critical region 3
DSE dermatan sulfate epimerase
DTWD1 DTW domain containing 1
DUS2 dihydrouridine synthase 2
DUSP10 dual specificity phosphatase 10
EHD4 EH-domain containing 4
EIF4B eukaryotic translation initiation factor 4B
EMC4 ER membrane protein complex subunit 4
EMC7 ER membrane protein complex subunit 7
ERMARD ER membrane-associated RNA degradation
ETFA electron-transfer-flavoprotein, alpha polypeptide
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EVA1C eva-1 homolog C (C. elegans)
FADS3 fatty acid desaturase 3
FAF1 Fas (TNFRSF6) associated factor 1
FAM110C family with sequence similarity 110, member C
FAM210A family with sequence similarity 210, member A
FAM21A family with sequence similarity 21, member A
FARSB phenylalanyl-tRNA synthetase, beta subunit
FBXL16 F-box and leucine-rich repeat protein 16
FBXO36 F-box protein 36
FBXW8 F-box and WD repeat domain containing 8
FEM1B fem-1 homolog b (C. elegans)
FOSL1 FOS-like antigen 1
FRMD5 FERM domain containing 5
FRRS1 ferric-chelate reductase 1
FSIP1 fibrous sheath interacting protein 1
FYB FYN binding protein
GALE UDP-galactose-4-epimerase
GALK2 galactokinase 2
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GLUD2 glutamate dehydrogenase 2
GMDS GDP-mannose 4,6-dehydratase
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNB5 guanine nucleotide binding protein (G protein), beta 5
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit
GOLGA6L1 golgin A6 family-like 1
GOLGA6L6 golgin A6 family-like 6
GOLGA8F golgin A8 family, member F
GOLPH3L golgi phosphoprotein 3-like
GPR152 G protein-coupled receptor 152
GSTO2 glutathione S-transferase omega 2
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HACD1 3-hydroxyacyl-CoA dehydratase 1
HACD2 3-hydroxyacyl-CoA dehydratase 2
HAGHL hydroxyacylglutathione hydrolase-like
HAUS2 HAUS augmin-like complex, subunit 2
HDAC1 histone deacetylase 1
HDAC9 histone deacetylase 9
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HPR haptoglobin-related protein
HPS1 Hermansky-Pudlak syndrome 1
HRK harakiri, BCL2 interacting protein
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HYPK huntingtin interacting protein K
IDI2 isopentenyl-diphosphate delta isomerase 2
IFI16 interferon, gamma-inducible protein 16
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFITM3 interferon induced transmembrane protein 3
IGFBP6 insulin-like growth factor binding protein 6
INTS10 integrator complex subunit 10
IQCH IQ motif containing H
IQGAP1 IQ motif containing GTPase activating protein 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRS1 insulin receptor substrate 1
IVD isovaleryl-CoA dehydrogenase
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDM4D lysine (K)-specific demethylase 4D
KIAA0196 KIAA0196
KLHL38 kelch-like family member 38
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
KRT31 keratin 31, type I
KRT80 keratin 80, type II
LACTB lactamase, beta
LCN2 lipocalin 2
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LEMD1 LEM domain containing 1
LIN52 lin-52 DREAM MuvB core complex component
LIPA lipase A, lysosomal acid, cholesterol esterase
LOC100134868 uncharacterized LOC100134868
LOC374443 C-type lectin domain family 2, member D pseudogene
LRRC28 leucine rich repeat containing 28
LRRC40 leucine rich repeat containing 40
LRRC57 leucine rich repeat containing 57
LYPLA2 lysophospholipase II
LYPLA2P1 lysophospholipase II pseudogene 1
MACC1 metastasis associated in colon cancer 1
MACROD1 MACRO domain containing 1
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene)
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK12 mitogen-activated protein kinase 12
MAPK6 mitogen-activated protein kinase 6
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MARS2 methionyl-tRNA synthetase 2, mitochondrial
MARVELD1 MARVEL domain containing 1
MB21D1 Mab-21 domain containing 1
MBP myelin basic protein
MCEE methylmalonyl CoA epimerase
MCPH1 microcephalin 1
MCTP1 multiple C2 domains, transmembrane 1
MCTP2 multiple C2 domains, transmembrane 2
MDFI MyoD family inhibitor
MECR mitochondrial trans-2-enoyl-CoA reductase
MEF2A myocyte enhancer factor 2A
METAP1D methionyl aminopeptidase type 1D (mitochondrial)
METRN meteorin, glial cell differentiation regulator
MFN2 mitofusin 2
MIIP migration and invasion inhibitory protein
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MORF4L1 mortality factor 4 like 1
MPHOSPH6 M-phase phosphoprotein 6
MPST mercaptopyruvate sulfurtransferase
MPV17 MpV17 mitochondrial inner membrane protein
MPV17L MPV17 mitochondrial membrane protein-like
MROH6 maestro heat-like repeat family member 6
MRPL10 mitochondrial ribosomal protein L10
MRPL46 mitochondrial ribosomal protein L46
MRPS18B mitochondrial ribosomal protein S18B
MRPS23 mitochondrial ribosomal protein S23
MT1E metallothionein 1E
MTCH2 mitochondrial carrier 2
MTFMT mitochondrial methionyl-tRNA formyltransferase
MTFR1 mitochondrial fission regulator 1
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NAPRT nicotinate phosphoribosyltransferase
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NDE1 nudE neurodevelopment protein 1
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NECAB3 N-terminal EF-hand calcium binding protein 3
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NGFR nerve growth factor receptor
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2
NME1-NME2 NME1-NME2 readthrough
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP10 NOP10 ribonucleoprotein
NPM3 nucleophosmin/nucleoplasmin 3
NPTN neuroplastin
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NSMCE1 non-SMC element 1 homolog (S. cerevisiae)
NSUN4 NOP2/Sun domain family, member 4
NUBPL nucleotide binding protein-like
NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22
OAZ3 ornithine decarboxylase antizyme 3
ODF2L outer dense fiber of sperm tails 2-like
OR7D2 olfactory receptor, family 7, subfamily D, member 2
ORC3 origin recognition complex, subunit 3
OSER1 oxidative stress responsive serine-rich 1
OSTM1 osteopetrosis associated transmembrane protein 1
PCBP2 poly(rC) binding protein 2
PCDHA11 protocadherin alpha 11
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PEF1 penta-EF-hand domain containing 1
PEX7 peroxisomal biogenesis factor 7
PGAM4 phosphoglycerate mutase family member 4
PGAM5 phosphoglycerate mutase family member 5
PGAP2 post-GPI attachment to proteins 2
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PLAU plasminogen activator, urokinase
PLCD3 phospholipase C, delta 3
PLEK2 pleckstrin 2
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
PML promyelocytic leukemia
PNPO pyridoxamine 5'-phosphate oxidase
POM121L4P POM121 transmembrane nucleoporin-like 4 pseudogene
PPIF peptidylprolyl isomerase F
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRMT8 protein arginine methyltransferase 8
PRRT4 proline-rich transmembrane protein 4
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTDSS2 phosphatidylserine synthase 2
PXMP2 peroxisomal membrane protein 2, 22kDa
PYGB phosphorylase, glycogen; brain
PYROXD2 pyridine nucleotide-disulphide oxidoreductase domain 2
R3HDM2 R3H domain containing 2
RAB11A RAB11A, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
REXO2 RNA exonuclease 2
RILPL2 Rab interacting lysosomal protein-like 2
RNF141 ring finger protein 141
RNF5P1 ring finger protein 5, E3 ubiquitin protein ligase pseudogene 1
RP1L1 retinitis pigmentosa 1-like 1
RPL4 ribosomal protein L4
RPLP1 ribosomal protein, large, P1
RPLP2 ribosomal protein, large, P2
RPP25 ribonuclease P/MRP 25kDa subunit
RPS17 ribosomal protein S17
RPS26 ribosomal protein S26
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPSAP52 ribosomal protein SA pseudogene 52
RPUSD4 RNA pseudouridylate synthase domain containing 4
RRP1 ribosomal RNA processing 1
RSC1A1 regulatory solute carrier protein, family 1, member 1
SARS seryl-tRNA synthetase
SDSL serine dehydratase-like
SEC11A SEC11 homolog A (S. cerevisiae)
SEC23IP SEC23 interacting protein
SERINC2 serine incorporator 2
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SESN2 sestrin 2
SH2D5 SH2 domain containing 5
SH3BP1 SH3-domain binding protein 1
SIAE sialic acid acetylesterase
SIN3A SIN3 transcription regulator family member A
SKOR1 SKI family transcriptional corepressor 1
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC22A15 solute carrier family 22, member 15
SLC22A18 solute carrier family 22, member 18
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC35F2 solute carrier family 35, member F2
SLC35F6 solute carrier family 35, member F6
SLC38A1 solute carrier family 38, member 1
SLC38A2 solute carrier family 38, member 2
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC43A3 solute carrier family 43, member 3
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SNAP23 synaptosomal-associated protein, 23kDa
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SNORA4 small nucleolar RNA, H/ACA box 4
SNUPN snurportin 1
SPATA5L1 spermatogenesis associated 5-like 1
SPDEF SAM pointed domain containing ETS transcription factor
SPG11 spastic paraplegia 11 (autosomal recessive)
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SPIRE1 spire-type actin nucleation factor 1
SQRDL sulfide quinone reductase-like (yeast)
SSTR5 somatostatin receptor 5
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STARD5 StAR-related lipid transfer (START) domain containing 5
STRIP2 striatin interacting protein 2
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
STYX serine/threonine/tyrosine interacting protein
SWAP70 SWAP switching B-cell complex 70kDa subunit
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
TIPIN TIMELESS interacting protein
TKFC triokinase/FMN cyclase
TLDC1 TBC/LysM-associated domain containing 1
TLX1 T-cell leukemia homeobox 1
TMEM171 transmembrane protein 171
TMEM194B transmembrane protein 194B
TMEM222 transmembrane protein 222
TMEM38A transmembrane protein 38A
TMEM87A transmembrane protein 87A
TMOD3 tropomodulin 3 (ubiquitous)
TMX2 thioredoxin-related transmembrane protein 2
TOMM34 translocase of outer mitochondrial membrane 34
TOX2 TOX high mobility group box family member 2
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
TRAP1 TNF receptor-associated protein 1
TRIB3 tribbles pseudokinase 3
TRIP4 thyroid hormone receptor interactor 4
TRMT5 tRNA methyltransferase 5
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TSTA3 tissue specific transplantation antigen P35B
TTC12 tetratricopeptide repeat domain 12
TUBGCP5 tubulin, gamma complex associated protein 5
TUFM Tu translation elongation factor, mitochondrial
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBE3D ubiquitin protein ligase E3D
UGCG UDP-glucose ceramide glucosyltransferase
UQCRC2 ubiquinol-cytochrome c reductase core protein II
USP3 ubiquitin specific peptidase 3
USP31 ubiquitin specific peptidase 31
USP8 ubiquitin specific peptidase 8
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
VWA9 von Willebrand factor A domain containing 9
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WASL Wiskott-Aldrich syndrome-like
WDR12 WD repeat domain 12
WDR24 WD repeat domain 24
WDR73 WD repeat domain 73
WDR76 WD repeat domain 76
YARS tyrosyl-tRNA synthetase
YIPF1 Yip1 domain family, member 1
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZDHHC7 zinc finger, DHHC-type containing 7
ZFYVE19 zinc finger, FYVE domain containing 19
ZNF598 zinc finger protein 598
ZNF774 zinc finger protein 774
ZRANB3 zinc finger, RAN-binding domain containing 3
ZSCAN31 zinc finger and SCAN domain containing 31
ZWILCH zwilch kinetochore protein

low expression

Symbol Name
ARMCX3 armadillo repeat containing, X-linked 3
BANP BTG3 associated nuclear protein
C9ORF64 chromosome 9 open reading frame 64
KIAA0100 KIAA0100
PAN3 PAN3 poly(A) specific ribonuclease subunit
PBRM1 polybromo 1
PPID peptidylprolyl isomerase D
PRKD3 protein kinase D3
SNX9 sorting nexin 9