Lung squamous cell carcinoma_LUSC_TCGA-56-A4ZK-01A-11R-A262-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

384 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-56-A4ZK-01A-11R-A262-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACAD10 acyl-CoA dehydrogenase family, member 10
ACOX3 acyl-CoA oxidase 3, pristanoyl
ACSF3 acyl-CoA synthetase family member 3
ADA adenosine deaminase
ADCK5 aarF domain containing kinase 5
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ADPRHL1 ADP-ribosylhydrolase like 1
AFG3L1P AFG3-like AAA ATPase 1, pseudogene
AHNAK2 AHNAK nucleoprotein 2
ALAD aminolevulinate dehydratase
ALOX12B arachidonate 12-lipoxygenase, 12R type
AMDHD1 amidohydrolase domain containing 1
AMH anti-Mullerian hormone
AMN amnion associated transmembrane protein
ANKRD9 ankyrin repeat domain 9
ANO8 anoctamin 8
ANP32A-IT1 ANP32A intronic transcript 1
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APOL1 apolipoprotein L, 1
APOL2 apolipoprotein L, 2
AQR aquarius intron-binding spliceosomal factor
ARGLU1 arginine and glutamate rich 1
ARHGAP27 Rho GTPase activating protein 27
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARTN artemin
ASCL2 achaete-scute family bHLH transcription factor 2
ASIC1 acid sensing (proton gated) ion channel 1
ATG2B autophagy related 2B
ATP4B ATPase, H+/K+ exchanging, beta polypeptide
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1
B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
BAG5 BCL2-associated athanogene 5
BBS2 Bardet-Biedl syndrome 2
BIVM basic, immunoglobulin-like variable motif containing
BMP7 bone morphogenetic protein 7
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C10ORF62 chromosome 10 open reading frame 62
C15ORF41 chromosome 15 open reading frame 41
C16ORF70 chromosome 16 open reading frame 70
C1ORF177 chromosome 1 open reading frame 177
C4ORF17 chromosome 4 open reading frame 17
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
CAPN14 calpain 14
CASKIN1 CASK interacting protein 1
CBR1 carbonyl reductase 1
CBWD3 COBW domain containing 3
CCNE2 cyclin E2
CCT6P1 chaperonin containing TCP1, subunit 6 (zeta) pseudogene 1
CD1B CD1b molecule
CDC16 cell division cycle 16
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDH16 cadherin 16, KSP-cadherin
CDK10 cyclin-dependent kinase 10
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CEP152 centrosomal protein 152kDa
CEP170B centrosomal protein 170B
CES2 carboxylesterase 2
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CKB creatine kinase, brain
CLLU1OS chronic lymphocytic leukemia up-regulated 1 opposite strand
CLUH clustered mitochondria (cluA/CLU1) homolog
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNOT6L CCR4-NOT transcription complex, subunit 6-like
COPS4 COP9 signalosome subunit 4
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
CORO6 coronin 6
CRHR1-IT1 CRHR1 intronic transcript 1
CROCC ciliary rootlet coiled-coil, rootletin
CRYGB crystallin, gamma B
CRYM-AS1 CRYM antisense RNA 1
CUL4A cullin 4A
CXCL9 chemokine (C-X-C motif) ligand 9
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene)
DBP D site of albumin promoter (albumin D-box) binding protein
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDHD1 DDHD domain containing 1
DHODH dihydroorotate dehydrogenase (quinone)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DIDO1 death inducer-obliterator 1
DIRC1 disrupted in renal carcinoma 1
DMRT2 doublesex and mab-3 related transcription factor 2
DMRT3 doublesex and mab-3 related transcription factor 3
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNM1 dynamin 1
DPF1 D4, zinc and double PHD fingers family 1
DPH3P1 diphthamide biosynthesis 3 pseudogene 1
DPH6 diphthamine biosynthesis 6
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EEF2K eukaryotic elongation factor 2 kinase
EHD3 EH-domain containing 3
EMC2 ER membrane protein complex subunit 2
EME2 essential meiotic structure-specific endonuclease subunit 2
EMILIN3 elastin microfibril interfacer 3
ENOPH1 enolase-phosphatase 1
EPHB6 EPH receptor B6
EPPK1 epiplakin 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAM117B family with sequence similarity 117, member B
FAM153A family with sequence similarity 153, member A
FAM219B family with sequence similarity 219, member B
FAM83C family with sequence similarity 83, member C
FAM98B family with sequence similarity 98, member B
FAN1 FANCD2/FANCI-associated nuclease 1
FANCA Fanconi anemia, complementation group A
FASTKD5 FAST kinase domains 5
FBXL16 F-box and leucine-rich repeat protein 16
FBXL21 F-box and leucine-rich repeat protein 21 (gene/pseudogene)
FBXL8 F-box and leucine-rich repeat protein 8
FBXO41 F-box protein 41
FETUB fetuin B
FOXN1 forkhead box N1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GAS8-AS1 GAS8 antisense RNA 1
GBP6 guanylate binding protein family, member 6
GDA guanine deaminase
GFOD1 glucose-fructose oxidoreductase domain containing 1
GID4 GID complex subunit 4
GMEB2 glucocorticoid modulatory element binding protein 2
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GPR135 G protein-coupled receptor 135
GPR52 G protein-coupled receptor 52
GRK1 G protein-coupled receptor kinase 1
GRTP1 growth hormone regulated TBC protein 1
GTPBP3 GTP binding protein 3 (mitochondrial)
GTSF1L gametocyte specific factor 1-like
HELQ helicase, POLQ-like
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HERC2P2 hect domain and RLD 2 pseudogene 2
HIST1H4G histone cluster 1, H4g
HIST3H3 histone cluster 3, H3
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOOK2 hook microtubule-tethering protein 2
HPSE heparanase
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSD17B7P2 hydroxysteroid (17-beta) dehydrogenase 7 pseudogene 2
HSF4 heat shock transcription factor 4
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA7 heat shock 70kDa protein 7 (HSP70B)
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IL4I1 interleukin 4 induced 1
INF2 inverted formin, FH2 and WH2 domain containing
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IREB2 iron-responsive element binding protein 2
IRX6 iroquois homeobox 6
ITPK1 inositol-tetrakisphosphate 1-kinase
IVD isovaleryl-CoA dehydrogenase
JMJD7-PLA2G4B JMJD7-PLA2G4B readthrough
KANK1 KN motif and ankyrin repeat domains 1
KAT2A K(lysine) acetyltransferase 2A
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCNK7 potassium channel, two pore domain subfamily K, member 7
KDM4C lysine (K)-specific demethylase 4C
KDM7A lysine (K)-specific demethylase 7A
KIAA0753 KIAA0753
KIAA0895L KIAA0895-like
KIAA2026 KIAA2026
KIFC2 kinesin family member C2
KLHL8 kelch-like family member 8
KLRG2 killer cell lectin-like receptor subfamily G, member 2
KNTC1 kinetochore associated 1
LAMA5 laminin, alpha 5
LAMP1 lysosomal-associated membrane protein 1
LIN54 lin-54 DREAM MuvB core complex component
LINC00161 long intergenic non-protein coding RNA 161
LKAAEAR1 LKAAEAR motif containing 1
LOC150776 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) pseudogene
LOC283922 pyruvate dehydrogenase phosphatase regulatory subunit pseudogene
LOC728392 uncharacterized LOC728392
LOC729609 uncharacterized LOC729609
LPAR5 lysophosphatidic acid receptor 5
LPCAT4 lysophosphatidylcholine acyltransferase 4
LPIN3 lipin 3
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC16B leucine rich repeat containing 16B
LRRC24 leucine rich repeat containing 24
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LRRC74A leucine rich repeat containing 74A
LTB4R leukotriene B4 receptor
LTB4R2 leukotriene B4 receptor 2
LUC7L2 LUC7-like 2 (S. cerevisiae)
MAMSTR MEF2 activating motif and SAP domain containing transcriptional regulator
MCF2L MCF.2 cell line derived transforming sequence-like
MCM3AP-AS1 MCM3AP antisense RNA 1
MFSD3 major facilitator superfamily domain containing 3
MINK1 misshapen-like kinase 1
MKNK1 MAP kinase interacting serine/threonine kinase 1
MKRN3 makorin ring finger protein 3
MLANA melan-A
MMP12 matrix metallopeptidase 12
MN1 meningioma (disrupted in balanced translocation) 1
MOB1B MOB kinase activator 1B
MSI1 musashi RNA-binding protein 1
MTA1 metastasis associated 1
MTAP methylthioadenosine phosphorylase
MTERF3 mitochondrial transcription termination factor 3
MTHFSD methenyltetrahydrofolate synthetase domain containing
MYO1H myosin IH
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit
NAGS N-acetylglutamate synthase
NAPB N-ethylmaleimide-sensitive factor attachment protein, beta
NDRG4 NDRG family member 4
NEURL2 neuralized E3 ubiquitin protein ligase 2
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1
NKPD1 NTPase, KAP family P-loop domain containing 1
NLGN2 neuroligin 2
NLRC5 NLR family, CARD domain containing 5
NLRP1 NLR family, pyrin domain containing 1
NLRP10 NLR family, pyrin domain containing 10
NOD2 nucleotide-binding oligomerization domain containing 2
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOL8 nucleolar protein 8
NR2E3 nuclear receptor subfamily 2, group E, member 3
NRDE2 NRDE-2, necessary for RNA interference, domain containing
OCLM oculomedin
OPHN1 oligophrenin 1
OR1J1 olfactory receptor, family 1, subfamily J, member 1
OR6C70 olfactory receptor, family 6, subfamily C, member 70
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PASD1 PAS domain containing 1
PAXBP1 PAX3 and PAX7 binding protein 1
PCDHGA1 protocadherin gamma subfamily A, 1
PCED1A PC-esterase domain containing 1A
PCID2 PCI domain containing 2
PCSK9 proprotein convertase subtilisin/kexin type 9
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGAP2 post-GPI attachment to proteins 2
PGBD2 piggyBac transposable element derived 2
PGBD4 piggyBac transposable element derived 4
PHLDB3 pleckstrin homology-like domain, family B, member 3
PITPNM3 PITPNM family member 3
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLA2G3 phospholipase A2, group III
PLAC8 placenta-specific 8
PLCD1 phospholipase C, delta 1
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4
PNPLA3 patatin-like phospholipase domain containing 3
POTED POTE ankyrin domain family, member D
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPIAL4E peptidylprolyl isomerase A (cyclophilin A)-like 4E
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma
PRCD progressive rod-cone degeneration
PRDM10 PR domain containing 10
PRIMA1 proline rich membrane anchor 1
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PTPRD protein tyrosine phosphatase, receptor type, D
PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
PWAR5 Prader Willi/Angelman region RNA 5
RAB40B RAB40B, member RAS oncogene family
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
RBM39 RNA binding motif protein 39
RCOR1 REST corepressor 1
RFPL1 ret finger protein-like 1
RIC1 RAB6A GEF complex partner 1
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF208 ring finger protein 208
RORA RAR-related orphan receptor A
RPRD1B regulation of nuclear pre-mRNA domain containing 1B
RRP1 ribosomal RNA processing 1
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
RUSC1-AS1 RUSC1 antisense RNA 1
SAGE1 sarcoma antigen 1
SAMD12 sterile alpha motif domain containing 12
SCRIB scribbled planar cell polarity protein
SDHAP1 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1
SDHAP2 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
SEPT5 septin 5
SGSM2 small G protein signaling modulator 2
SHISA6 shisa family member 6
SHPK sedoheptulokinase
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29
SLC4A11 solute carrier family 4, sodium borate transporter, member 11
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC7A5P2 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLURP1 secreted LY6/PLAUR domain containing 1
SMCR5 Smith-Magenis syndrome chromosome region, candidate 5 (non-protein coding)
SMYD4 SET and MYND domain containing 4
SND1-IT1 SND1 intronic transcript 1
SNORA61 small nucleolar RNA, H/ACA box 61
SNORA71E small nucleolar RNA, H/ACA box 71E
SNORD116-28 small nucleolar RNA, C/D box 116-28
SNX5 sorting nexin 5
SPARCL1 SPARC-like 1 (hevin)
SPATA25 spermatogenesis associated 25
SREBF1 sterol regulatory element binding transcription factor 1
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
STX16 syntaxin 16
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
TARBP1 TAR (HIV-1) RNA binding protein 1
TAS2R4 taste receptor, type 2, member 4
TESK2 testis-specific kinase 2
TFDP1 transcription factor Dp-1
TGM3 transglutaminase 3
TGM6 transglutaminase 6
THAP6 THAP domain containing 6
THAP9 THAP domain containing 9
THSD7B thrombospondin, type I, domain containing 7B
TIFAB TRAF-interacting protein with forkhead-associated domain, family member B
TIGD5 tigger transposable element derived 5
TLDC2 TBC/LysM-associated domain containing 2
TMCO3 transmembrane and coiled-coil domains 3
TMEM116 transmembrane protein 116
TMEM179 transmembrane protein 179
TMEM255B transmembrane protein 255B
TNK2 tyrosine kinase, non-receptor, 2
TOP3A topoisomerase (DNA) III alpha
TRAF3 TNF receptor-associated factor 3
TRMT61A tRNA methyltransferase 61A
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TSPEAR thrombospondin-type laminin G domain and EAR repeats
TSPEAR-AS2 TSPEAR antisense RNA 2
TTC22 tetratricopeptide repeat domain 22
TTC39B tetratricopeptide repeat domain 39B
TUBGCP3 tubulin, gamma complex associated protein 3
TUBGCP5 tubulin, gamma complex associated protein 5
TYRO3 TYRO3 protein tyrosine kinase
UBA6 ubiquitin-like modifier activating enzyme 6
UBE3A ubiquitin protein ligase E3A
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
ULK3 unc-51 like kinase 3
UNC79 unc-79 homolog (C. elegans)
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
USP35 ubiquitin specific peptidase 35
VLDLR very low density lipoprotein receptor
VN1R1 vomeronasal 1 receptor 1
VPS9D1 VPS9 domain containing 1
WARS tryptophanyl-tRNA synthetase
WASH3P WAS protein family homolog 3 pseudogene
WDR20 WD repeat domain 20
WDR24 WD repeat domain 24
WDR90 WD repeat domain 90
WFDC5 WAP four-disulfide core domain 5
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB1 zinc finger and BTB domain containing 1
ZCCHC6 zinc finger, CCHC domain containing 6
ZDHHC11 zinc finger, DHHC-type containing 11
ZDHHC21 zinc finger, DHHC-type containing 21
ZFP41 ZFP41 zinc finger protein
ZFP64 ZFP64 zinc finger protein
ZNF174 zinc finger protein 174
ZNF252P-AS1 ZNF252P antisense RNA 1
ZNF263 zinc finger protein 263
ZNF276 zinc finger protein 276
ZNF334 zinc finger protein 334
ZNF343 zinc finger protein 343
ZNF404 zinc finger protein 404
ZNF497 zinc finger protein 497
ZNF500 zinc finger protein 500
ZNF512B zinc finger protein 512B
ZNF517 zinc finger protein 517
ZNF556 zinc finger protein 556
ZNF572 zinc finger protein 572
ZNF594 zinc finger protein 594
ZNF696 zinc finger protein 696
ZNF7 zinc finger protein 7
ZNF707 zinc finger protein 707
ZNF750 zinc finger protein 750
ZNF770 zinc finger protein 770
ZNF782 zinc finger protein 782

low expression

Symbol Name
ARCN1 archain 1
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)