Lung squamous cell carcinoma_LUSC_TCGA-56-8504-01A-11R-2403-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

335 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-56-8504-01A-11R-2403-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AADAC arylacetamide deacetylase
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ABHD2 abhydrolase domain containing 2
ABHD4 abhydrolase domain containing 4
ACAD9 acyl-CoA dehydrogenase family, member 9
ADCK1 aarF domain containing kinase 1
ADORA2B adenosine A2b receptor
ADRBK1 adrenergic, beta, receptor kinase 1
AGFG2 ArfGAP with FG repeats 2
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ALOX15 arachidonate 15-lipoxygenase
ALS2CR11 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
AP5M1 adaptor-related protein complex 5, mu 1 subunit
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOPT1 apoptogenic 1, mitochondrial
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ASCC2 activating signal cointegrator 1 complex subunit 2
ATG10 autophagy related 10
ATG2B autophagy related 2B
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
ATXN3 ataxin 3
AXDND1 axonemal dynein light chain domain containing 1
BAG5 BCL2-associated athanogene 5
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BMP7 bone morphogenetic protein 7
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BRMS1 breast cancer metastasis suppressor 1
BTBD6 BTB (POZ) domain containing 6
BTBD7 BTB (POZ) domain containing 7
C11ORF80 chromosome 11 open reading frame 80
C14ORF1 chromosome 14 open reading frame 1
C14ORF159 chromosome 14 open reading frame 159
C14ORF169 chromosome 14 open reading frame 169
C21ORF33 chromosome 21 open reading frame 33
C2ORF47 chromosome 2 open reading frame 47
C7ORF50 chromosome 7 open reading frame 50
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCDC85C coiled-coil domain containing 85C
CCDC87 coiled-coil domain containing 87
CCDC88C coiled-coil domain containing 88C
CCL26 chemokine (C-C motif) ligand 26
CCNK cyclin K
CCNYL1 cyclin Y-like 1
CCS copper chaperone for superoxide dismutase
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDCA4 cell division cycle associated 4
CDKN3 cyclin-dependent kinase inhibitor 3
CENPU centromere protein U
CEP128 centrosomal protein 128kDa
CEP170B centrosomal protein 170B
CHD3 chromodomain helicase DNA binding protein 3
CHD9 chromodomain helicase DNA binding protein 9
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CINP cyclin-dependent kinase 2 interacting protein
CIPC CLOCK-interacting pacemaker
CLUH clustered mitochondria (cluA/CLU1) homolog
COBLL1 cordon-bleu WH2 repeat protein-like 1
COG4 component of oligomeric golgi complex 4
COQ6 coenzyme Q6 monooxygenase
CORO1B coronin, actin binding protein, 1B
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CPVL carboxypeptidase, vitellogenic-like
CRACR2A calcium release activated channel regulator 2A
CRCP CGRP receptor component
CT83 cancer/testis antigen 83
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
CTAGE5 CTAGE family, member 5
CTF1 cardiotrophin 1
DCAF4 DDB1 and CUL4 associated factor 4
DCAF5 DDB1 and CUL4 associated factor 5
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DEGS2 delta(4)-desaturase, sphingolipid 2
DHRS4 dehydrogenase/reductase (SDR family) member 4
DHRS4L2 dehydrogenase/reductase (SDR family) member 4 like 2
DHRSX dehydrogenase/reductase (SDR family) X-linked
DIAPH3 diaphanous-related formin 3
DICER1 dicer 1, ribonuclease type III
DIS3L DIS3 like exosome 3'-5' exoribonuclease
DLD dihydrolipoamide dehydrogenase
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DMC1 DNA meiotic recombinase 1
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DPP3 dipeptidyl-peptidase 3
DTD2 D-tyrosyl-tRNA deacylase 2 (putative)
DUS2 dihydrouridine synthase 2
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
ECHDC3 enoyl CoA hydratase domain containing 3
EFCAB11 EF-hand calcium binding domain 11
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF5 eukaryotic translation initiation factor 5
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPYC epiphycan
ETFB electron-transfer-flavoprotein, beta polypeptide
EXOC5 exocyst complex component 5
FAM102A family with sequence similarity 102, member A
FANCM Fanconi anemia, complementation group M
FASTKD1 FAST kinase domains 1
FASTKD2 FAST kinase domains 2
FBRS fibrosin
FCF1 FCF1 rRNA-processing protein
FKBP3 FK506 binding protein 3, 25kDa
FOXM1 forkhead box M1
G6PD glucose-6-phosphate dehydrogenase
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GBP6 guanylate binding protein family, member 6
GLOD4 glyoxalase domain containing 4
GLRX5 glutaredoxin 5
GOLGA5 golgin A5
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPATCH2L G patch domain containing 2-like
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPHN gephyrin
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2
GSTM3 glutathione S-transferase mu 3 (brain)
GSTM4 glutathione S-transferase mu 4
GSTP1 glutathione S-transferase pi 1
GSTZ1 glutathione S-transferase zeta 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2I general transcription factor IIi
GTSE1 G-2 and S-phase expressed 1
HAT1 histone acetyltransferase 1
HEATR3 HEAT repeat containing 3
HEATR9 HEAT repeat containing 9
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BH histone cluster 1, H2bh
HIST1H2BL histone cluster 1, H2bl
HIST2H2AC histone cluster 2, H2ac
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA7 homeobox A7
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
IFI27 interferon, alpha-inducible protein 27
IFI27L1 interferon, alpha-inducible protein 27-like 1
IPMK inositol polyphosphate multikinase
ISCA2 iron-sulfur cluster assembly 2
ITFG1 integrin alpha FG-GAP repeat containing 1
ITPK1 inositol-tetrakisphosphate 1-kinase
KBTBD13 kelch repeat and BTB (POZ) domain containing 13
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCTD18 potassium channel tetramerization domain containing 18
KDM2A lysine (K)-specific demethylase 2A
KDM5A lysine (K)-specific demethylase 5A
KLC1 kinesin light chain 1
KLC2 kinesin light chain 2
L2HGDH L-2-hydroxyglutarate dehydrogenase
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LGALS8 lectin, galactoside-binding, soluble, 8
LIAS lipoic acid synthetase
LIN52 lin-52 DREAM MuvB core complex component
LMO1 LIM domain only 1 (rhombotin 1)
LOC100133669 uncharacterized LOC100133669
LOC154449 uncharacterized LOC154449
LONP2 lon peptidase 2, peroxisomal
LPCAT3 lysophosphatidylcholine acyltransferase 3
LRIF1 ligand dependent nuclear receptor interacting factor 1
LY6D lymphocyte antigen 6 complex, locus D
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
MARS2 methionyl-tRNA synthetase 2, mitochondrial
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MED6 mediator complex subunit 6
METTL8 methyltransferase like 8
MKNK2 MAP kinase interacting serine/threonine kinase 2
MLH3 mutL homolog 3
MOV10 Mov10 RISC complex RNA helicase
MRPL11 mitochondrial ribosomal protein L11
MRPL23 mitochondrial ribosomal protein L23
MTA1 metastasis associated 1
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MX1 MX dynamin-like GTPase 1
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit
NAMPT nicotinamide phosphoribosyltransferase
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NEK9 NIMA-related kinase 9
NEMF nuclear export mediator factor
NKX1-2 NK1 homeobox 2
NRDE2 NRDE-2, necessary for RNA interference, domain containing
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUBPL nucleotide binding protein-like
NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8
NUMB numb homolog (Drosophila)
NYNRIN NYN domain and retroviral integrase containing
OAT ornithine aminotransferase
OR1F2P olfactory receptor, family 1, subfamily F, member 2, pseudogene
ORC6 origin recognition complex, subunit 6
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PACS2 phosphofurin acidic cluster sorting protein 2
PADI3 peptidyl arginine deiminase, type III
PAPOLA poly(A) polymerase alpha
PARP9 poly (ADP-ribose) polymerase family, member 9
PC pyruvate carboxylase
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCNX pecanex homolog (Drosophila)
PCP4L1 Purkinje cell protein 4 like 1
PGD phosphogluconate dehydrogenase
PHKB phosphorylase kinase, beta
PHKG2 phosphorylase kinase, gamma 2 (testis)
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKDREJ polycystin (PKD) family receptor for egg jelly
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLAC1 placenta-specific 1
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POMT2 protein-O-mannosyltransferase 2
POR P450 (cytochrome) oxidoreductase
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRMT7 protein arginine methyltransferase 7
PRR14 proline rich 14
PSEN1 presenilin 1
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PTGR2 prostaglandin reductase 2
PYY2 peptide YY, 2 (pseudogene)
QRFPR pyroglutamylated RFamide peptide receptor
RAB1B RAB1B, member RAS oncogene family
RAI1 retinoic acid induced 1
RBM15 RNA binding motif protein 15
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RHBDD3 rhomboid domain containing 3
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1
RNASE10 ribonuclease, RNase A family, 10 (non-active)
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RRM1 ribonucleotide reductase M1
SCO1 SCO1 cytochrome c oxidase assembly protein
SCRN3 secernin 3
SF3B2 splicing factor 3b, subunit 2, 145kDa
SH3BP1 SH3-domain binding protein 1
SHCBP1 SHC SH2-domain binding protein 1
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC22A18 solute carrier family 22, member 18
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC38A6 solute carrier family 38, member 6
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2
SLFN5 schlafen family member 5
SLIRP SRA stem-loop interacting RNA binding protein
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SNW1 SNW domain containing 1
SOX15 SRY (sex determining region Y)-box 15
SPATS2L spermatogenesis associated, serine-rich 2-like
SPTBN2 spectrin, beta, non-erythrocytic 2
SRCAP Snf2-related CREBBP activator protein
SRY sex determining region Y
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
STX4 syntaxin 4
STYK1 serine/threonine/tyrosine kinase 1
SULT1C3 sulfotransferase family, cytosolic, 1C, member 3
SYNJ2BP synaptojanin 2 binding protein
SYTL1 synaptotagmin-like 1
TALDO1 transaldolase 1
TBC1D10B TBC1 domain family, member 10B
TCF23 transcription factor 23
TCHH trichohyalin
TDP1 tyrosyl-DNA phosphodiesterase 1
TECPR2 tectonin beta-propeller repeat containing 2
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMED10P1 transmembrane emp24-like trafficking protein 10 (yeast) pseudogene 1
TMEM11 transmembrane protein 11
TMEM134 transmembrane protein 134
TMEM194B transmembrane protein 194B
TMEM63C transmembrane protein 63C
TPPP2 tubulin polymerization-promoting protein family member 2
TRIL TLR4 interactor with leucine-rich repeats
TRIP11 thyroid hormone receptor interactor 11
TRMT61A tRNA methyltransferase 61A
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TTC7B tetratricopeptide repeat domain 7B
TTC8 tetratricopeptide repeat domain 8
TTF2 transcription termination factor, RNA polymerase II
TTLL5 tubulin tyrosine ligase-like family member 5
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative)
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VANGL1 VANGL planar cell polarity protein 1
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
VRK1 vaccinia related kinase 1
VSIG10L V-set and immunoglobulin domain containing 10 like
VTI1B vesicle transport through interaction with t-SNAREs 1B
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR20 WD repeat domain 20
WDR3 WD repeat domain 3
WDR77 WD repeat domain 77
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YLPM1 YLP motif containing 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZC3H14 zinc finger CCCH-type containing 14
ZCCHC2 zinc finger, CCHC domain containing 2
ZDHHC24 zinc finger, DHHC-type containing 24
ZFY zinc finger protein, Y-linked
ZFYVE1 zinc finger, FYVE domain containing 1
ZHX2 zinc fingers and homeoboxes 2
ZNF629 zinc finger protein 629
ZNF688 zinc finger protein 688
ZNF689 zinc finger protein 689
ZNF747 zinc finger protein 747
ZNF764 zinc finger protein 764
ZNF768 zinc finger protein 768
ZNF839 zinc finger protein 839

low expression

Symbol Name
GIGYF2 GRB10 interacting GYF protein 2
STX5 syntaxin 5
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
ZNF845 zinc finger protein 845