Lung squamous cell carcinoma_LUSC_TCGA-56-8308-01A-11R-2296-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

327 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-56-8308-01A-11R-2296-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACTRT3 actin-related protein T3
ADAM20 ADAM metallopeptidase domain 20
ADAM23 ADAM metallopeptidase domain 23
ADRA2C adrenoceptor alpha 2C
AGO4 argonaute RISC catalytic component 4
ANKRD13C ankyrin repeat domain 13C
ANKRD36BP1 ankyrin repeat domain 36B pseudogene 1
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL8B ADP-ribosylation factor-like 8B
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ASB17 ankyrin repeat and SOCS box containing 17
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
BAG3 BCL2-associated athanogene 3
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BCL3 B-cell CLL/lymphoma 3
BICD2 bicaudal D homolog 2 (Drosophila)
BIRC2 baculoviral IAP repeat containing 2
BIRC6 baculoviral IAP repeat containing 6
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3
C11ORF68 chromosome 11 open reading frame 68
C11ORF74 chromosome 11 open reading frame 74
C11ORF84 chromosome 11 open reading frame 84
C11ORF94 chromosome 11 open reading frame 94
C11ORF95 chromosome 11 open reading frame 95
C15ORF56 chromosome 15 open reading frame 56
C15ORF59 chromosome 15 open reading frame 59
C17ORF82 chromosome 17 open reading frame 82
C3ORF22 chromosome 3 open reading frame 22
C4ORF51 chromosome 4 open reading frame 51
C6ORF10 chromosome 6 open reading frame 10
C6ORF47 chromosome 6 open reading frame 47
CCDC90B coiled-coil domain containing 90B
CCDC97 coiled-coil domain containing 97
CCNDBP1 cyclin D-type binding-protein 1
CDH8 cadherin 8, type 2
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIC capicua transcriptional repressor
CLDN20 claudin 20
CLPTM1 cleft lip and palate associated transmembrane protein 1
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNTLN centlein, centrosomal protein
CNTNAP2 contactin associated protein-like 2
COMMD9 COMM domain containing 9
CPA6 carboxypeptidase A6
CPXM2 carboxypeptidase X (M14 family), member 2
CREBZF CREB/ATF bZIP transcription factor
CRHR1-IT1 CRHR1 intronic transcript 1
CRTC2 CREB regulated transcription coactivator 2
CSRP2BP CSRP2 binding protein
CSTL1 cystatin-like 1
CTNND1 catenin (cadherin-associated protein), delta 1
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
DACT2 dishevelled-binding antagonist of beta-catenin 2
DCAF10 DDB1 and CUL4 associated factor 10
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae)
DDIAS DNA damage-induced apoptosis suppressor
DENND4B DENN/MADD domain containing 4B
DLK2 delta-like 2 homolog (Drosophila)
DNAJB3 DnaJ (Hsp40) homolog, subfamily B, member 3
DOCK7 dedicator of cytokinesis 7
DUSP14 dual specificity phosphatase 14
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYNLT3 dynein, light chain, Tctex-type 3
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EDN1 endothelin 1
EED embryonic ectoderm development
EFNA1 ephrin-A1
EFNB2 ephrin-B2
EIF5A2 eukaryotic translation initiation factor 5A2
EML2 echinoderm microtubule associated protein like 2
EMP1 epithelial membrane protein 1
EN2 engrailed homeobox 2
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
ERC2 ELKS/RAB6-interacting/CAST family member 2
ERF Ets2 repressor factor
ETHE1 ethylmalonic encephalopathy 1
ETV3 ets variant 3
EXT2 exostosin glycosyltransferase 2
FAM120B family with sequence similarity 120B
FAM135A family with sequence similarity 135, member A
FAM181B family with sequence similarity 181, member B
FAM227B family with sequence similarity 227, member B
FAM50B family with sequence similarity 50, member B
FAM83B family with sequence similarity 83, member B
FBXO11 F-box protein 11
FBXW4 F-box and WD repeat domain containing 4
FERMT1 fermitin family member 1
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGFR2 fibroblast growth factor receptor 2
FJX1 four jointed box 1 (Drosophila)
FKRP fukutin related protein
FLJ10038 uncharacterized protein FLJ10038
FNDC3B fibronectin type III domain containing 3B
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXE1 forkhead box E1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GDA guanine deaminase
GFOD1 glucose-fructose oxidoreductase domain containing 1
GGACT gamma-glutamylamine cyclotransferase
GPI glucose-6-phosphate isomerase
GPR137 G protein-coupled receptor 137
GPR160 G protein-coupled receptor 160
GPRC5D G protein-coupled receptor, class C, group 5, member D
GSK3A glycogen synthase kinase 3 alpha
GTSE1-AS1 GTSE1 antisense RNA 1 (head to head)
HAS3 hyaluronan synthase 3
HOXC8 homeobox C8
HPYR1 Helicobacter pylori responsive 1 (non-protein coding)
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
HUS1B HUS1 checkpoint homolog b (S. pombe)
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IGF1R insulin-like growth factor 1 receptor
IGHMBP2 immunoglobulin mu binding protein 2
IGSF11 immunoglobulin superfamily, member 11
IGSF8 immunoglobulin superfamily, member 8
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRGQ immunity-related GTPase family, Q
JRKL JRK-like
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCTD21 potassium channel tetramerization domain containing 21
KIAA0319L KIAA0319-like
KIAA1045 KIAA1045
KIAA1549L KIAA1549-like
KLC3 kinesin light chain 3
KLF4 Kruppel-like factor 4 (gut)
KLF8 Kruppel-like factor 8
KMT2C lysine (K)-specific methyltransferase 2C
KRT6A keratin 6A, type II
KRTAP13-1 keratin associated protein 13-1
KRTAP19-1 keratin associated protein 19-1
KRTAP21-2 keratin associated protein 21-2
LCE6A late cornified envelope 6A
LDLRAD3 low density lipoprotein receptor class A domain containing 3
LENEP lens epithelial protein
LINC00112 long intergenic non-protein coding RNA 112
LINC00161 long intergenic non-protein coding RNA 161
LINC00472 long intergenic non-protein coding RNA 472
LINC01011 long intergenic non-protein coding RNA 1011
LOC100132215 uncharacterized LOC100132215
LOC100270746 uncharacterized LOC100270746
LOC391322 D-dopachrome tautomerase-like
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC34 leucine rich repeat containing 34
LRRC4 leucine rich repeat containing 4
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MCHR2 melanin-concentrating hormone receptor 2
MEF2D myocyte enhancer factor 2D
MEGF10 multiple EGF-like-domains 10
MERTK MER proto-oncogene, tyrosine kinase
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MRPL42P5 mitochondrial ribosomal protein L42 pseudogene 5
MYADML2 myeloid-associated differentiation marker-like 2
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2
NCDN neurochondrin
NCSTN nicastrin
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NFE2L1 nuclear factor, erythroid 2-like 1
NFE2L2 nuclear factor, erythroid 2-like 2
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1
NKAIN1 Na+/K+ transporting ATPase interacting 1
NKPD1 NTPase, KAP family P-loop domain containing 1
NLGN1 neuroligin 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOM1 nucleolar protein with MIF4G domain 1
NOTCH2NL notch 2 N-terminal like
NPAS2 neuronal PAS domain protein 2
NRP2 neuropilin 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUMA1 nuclear mitotic apparatus protein 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR10V1 olfactory receptor, family 10, subfamily V, member 1
OR1J1 olfactory receptor, family 1, subfamily J, member 1
OR2A14 olfactory receptor, family 2, subfamily A, member 14
OR4D10 olfactory receptor, family 4, subfamily D, member 10
OR4F21 olfactory receptor, family 4, subfamily F, member 21
OR51I1 olfactory receptor, family 51, subfamily I, member 1
OR5AP2 olfactory receptor, family 5, subfamily AP, member 2
OR5B21 olfactory receptor, family 5, subfamily B, member 21
OR6C2 olfactory receptor, family 6, subfamily C, member 2
OR6C70 olfactory receptor, family 6, subfamily C, member 70
ORAI3 ORAI calcium release-activated calcium modulator 3
PABPC1P2 poly(A) binding protein, cytoplasmic 1 pseudogene 2
PACS1 phosphofurin acidic cluster sorting protein 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAPL iron/zinc purple acid phosphatase-like protein
PCDHB14 protocadherin beta 14
PCDHB17P protocadherin beta 17 pseudogene
PCDHB4 protocadherin beta 4
PCF11 PCF11 cleavage and polyadenylation factor subunit
PELI1 pellino E3 ubiquitin protein ligase 1
PGAP1 post-GPI attachment to proteins 1
PGBD1 piggyBac transposable element derived 1
PHC3 polyhomeotic homolog 3 (Drosophila)
PHLDB3 pleckstrin homology-like domain, family B, member 3
PICALM phosphatidylinositol binding clathrin assembly protein
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2R1 phospholipase A2 receptor 1, 180kDa
PLAC8 placenta-specific 8
PLAGL1 pleiomorphic adenoma gene-like 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLEKHM1P pleckstrin homology domain containing, family M (with RUN domain) member 1 pseudogene
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PNMAL2 paraneoplastic Ma antigen family-like 2
POU6F1 POU class 6 homeobox 1
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PPME1 protein phosphatase methylesterase 1
PPP1R3G protein phosphatase 1, regulatory subunit 3G
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme
PRCC papillary renal cell carcinoma (translocation-associated)
PRCP prolylcarboxypeptidase (angiotensinase C)
PRDM11 PR domain containing 11
PRKCI protein kinase C, iota
PRR5L proline rich 5 like
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
PVRL4 poliovirus receptor-related 4
PYGO2 pygopus family PHD finger 2
RAB30 RAB30, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAB6C RAB6C, member RAS oncogene family
RAET1L retinoic acid early transcript 1L
RAG1 recombination activating gene 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RCOR2 REST corepressor 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFPL3 ret finger protein-like 3
RND3 Rho family GTPase 3
RNF121 ring finger protein 121
RNF38 ring finger protein 38
RNF39 ring finger protein 39
RORA RAR-related orphan receptor A
RSPH3 radial spoke 3 homolog (Chlamydomonas)
SAMD12 sterile alpha motif domain containing 12
SCN9A sodium channel, voltage gated, type IX alpha subunit
SDCBP2 syndecan binding protein (syntenin) 2
SDK2 sidekick cell adhesion molecule 2
SEC62 SEC62 homolog (S. cerevisiae)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SFT2D2 SFT2 domain containing 2
SGK1 serum/glucocorticoid regulated kinase 1
SHB Src homology 2 domain containing adaptor protein B
SKIL SKI-like proto-oncogene
SLAMF9 SLAM family member 9
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC25A51 solute carrier family 25, member 51
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC35B3 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
SLC38A10 solute carrier family 38, member 10
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMCO2 single-pass membrane protein with coiled-coil domains 2
SND1-IT1 SND1 intronic transcript 1
SNORA4 small nucleolar RNA, H/ACA box 4
SNORA55 small nucleolar RNA, H/ACA box 55
SNORA65 small nucleolar RNA, H/ACA box 65
SOX2 SRY (sex determining region Y)-box 2
SOX21 SRY (sex determining region Y)-box 21
SP2 Sp2 transcription factor
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SSR4P1 signal sequence receptor, delta pseudogene 1
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
SYCE3 synaptonemal complex central element protein 3
TACSTD2 tumor-associated calcium signal transducer 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TERC telomerase RNA component
THSD7B thrombospondin, type I, domain containing 7B
TICAM1 toll-like receptor adaptor molecule 1
TLN2 talin 2
TMEM123 transmembrane protein 123
TMEM246 transmembrane protein 246
TMEM260 transmembrane protein 260
TMUB1 transmembrane and ubiquitin-like domain containing 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM44 tripartite motif containing 44
TSHZ2 teashirt zinc finger homeobox 2
TSPAN18 tetraspanin 18
TTTY10 testis-specific transcript, Y-linked 10 (non-protein coding)
UBOX5 U-box domain containing 5
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
USP35 ubiquitin specific peptidase 35
USP40 ubiquitin specific peptidase 40
UVRAG UV radiation resistance associated
WIPF3 WAS/WASL interacting protein family, member 3
WWC2-AS2 WWC2 antisense RNA 2
YAP1 Yes-associated protein 1
YY1AP1 YY1 associated protein 1
ZBED9 zinc finger, BED-type containing 9
ZBTB22 zinc finger and BTB domain containing 22
ZBTB5 zinc finger and BTB domain containing 5
ZBTB7B zinc finger and BTB domain containing 7B
ZDHHC5 zinc finger, DHHC-type containing 5
ZMAT3 zinc finger, matrin-type 3
ZNF155 zinc finger protein 155
ZNF222 zinc finger protein 222
ZNF227 zinc finger protein 227
ZNF234 zinc finger protein 234
ZNF267 zinc finger protein 267
ZNF526 zinc finger protein 526
ZNF574 zinc finger protein 574
ZNF575 zinc finger protein 575

low expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ERCC8 excision repair cross-complementation group 8
GPBP1 GC-rich promoter binding protein 1
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
MIER3 mesoderm induction early response 1, family member 3
SMIM15 small integral membrane protein 15