Lung squamous cell carcinoma_LUSC_TCGA-56-7582-01A-11R-2045-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

440 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-56-7582-01A-11R-2045-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACO2 aconitase 2, mitochondrial
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ACVR1 activin A receptor, type I
ADAM17 ADAM metallopeptidase domain 17
ADCY3 adenylate cyclase 3
ADSS adenylosuccinate synthase
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AHCYL1 adenosylhomocysteinase-like 1
AHR aryl hydrocarbon receptor
AKIRIN2 akirin 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMMECR1L AMMECR1-like
ANAPC1 anaphase promoting complex subunit 1
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
ARID2 AT rich interactive domain 2 (ARID, RFX-like)
ARL5A ADP-ribosylation factor-like 5A
ASCC3 activating signal cointegrator 1 complex subunit 3
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ASXL2 additional sex combs like transcriptional regulator 2
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATRX alpha thalassemia/mental retardation syndrome X-linked
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BCO1 beta-carotene oxygenase 1
BICD2 bicaudal D homolog 2 (Drosophila)
BIRC6 baculoviral IAP repeat containing 6
BRAP BRCA1 associated protein
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BROX BRO1 domain and CAAX motif containing
BRPF3 bromodomain and PHD finger containing, 3
BTBD8 BTB (POZ) domain containing 8
C12ORF75 chromosome 12 open reading frame 75
C1ORF110 chromosome 1 open reading frame 110
C1ORF229 chromosome 1 open reading frame 229
CA12 carbonic anhydrase XII
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CASC5 cancer susceptibility candidate 5
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CASP8AP2 caspase 8 associated protein 2
CCDC177 coiled-coil domain containing 177
CCNC cyclin C
CCSER1 coiled-coil serine-rich protein 1
CD2AP CD2-associated protein
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC5L cell division cycle 5-like
CDK17 cyclin-dependent kinase 17
CECR2 cat eye syndrome chromosome region, candidate 2
CEP162 centrosomal protein 162kDa
CEP350 centrosomal protein 350kDa
CERS6 ceramide synthase 6
CES1 carboxylesterase 1
CHAT choline O-acetyltransferase
CHD9 chromodomain helicase DNA binding protein 9
CHMP3 charged multivesicular body protein 3
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CKAP2L cytoskeleton associated protein 2-like
CLASP1 cytoplasmic linker associated protein 1
CLIP1 CAP-GLY domain containing linker protein 1
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLTC clathrin, heavy chain (Hc)
CNOT4 CCR4-NOT transcription complex, subunit 4
COQ3 coenzyme Q3 methyltransferase
CORO1C coronin, actin binding protein, 1C
CPEB2 cytoplasmic polyadenylation element binding protein 2
CPEB4 cytoplasmic polyadenylation element binding protein 4
CPLX2 complexin 2
CPNE4 copine IV
CPNE8 copine VIII
CREB5 cAMP responsive element binding protein 5
CTTNBP2NL CTTNBP2 N-terminal like
CYB5R4 cytochrome b5 reductase 4
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
DDIAS DNA damage-induced apoptosis suppressor
DENND2C DENN/MADD domain containing 2C
DENND4A DENN/MADD domain containing 4A
DIAPH2 diaphanous-related formin 2
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DIRAS2 DIRAS family, GTP-binding RAS-like 2
DIS3L DIS3 like exosome 3'-5' exoribonuclease
DMC1 DNA meiotic recombinase 1
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
DOPEY1 dopey family member 1
DPP8 dipeptidyl-peptidase 8
DSC2 desmocollin 2
DSC3 desmocollin 3
DSEL dermatan sulfate epimerase-like
DSG4 desmoglein 4
DST dystonin
DSTYK dual serine/threonine and tyrosine protein kinase
EEA1 early endosome antigen 1
EHBP1 EH domain binding protein 1
EIF3L eukaryotic translation initiation factor 3, subunit L
ELF1 E74-like factor 1 (ets domain transcription factor)
ELOVL4 ELOVL fatty acid elongase 4
ELOVL5 ELOVL fatty acid elongase 5
EMC2 ER membrane protein complex subunit 2
EN2 engrailed homeobox 2
EP300 E1A binding protein p300
EPC2 enhancer of polycomb homolog 2 (Drosophila)
EPHA3 EPH receptor A3
EPS8 epidermal growth factor receptor pathway substrate 8
EPT1 ethanolaminephosphotransferase 1
EWSAT1 Ewing sarcoma associated transcript 1
EXT1 exostosin glycosyltransferase 1
EYA1 EYA transcriptional coactivator and phosphatase 1
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM110B family with sequence similarity 110, member B
FAM117B family with sequence similarity 117, member B
FAM122A family with sequence similarity 122A
FAM126A family with sequence similarity 126, member A
FAM135A family with sequence similarity 135, member A
FAM168B family with sequence similarity 168, member B
FAM171B family with sequence similarity 171, member B
FAM83B family with sequence similarity 83, member B
FAM91A1 family with sequence similarity 91, member A1
FBXL4 F-box and leucine-rich repeat protein 4
FEM1B fem-1 homolog b (C. elegans)
FGFBP2 fibroblast growth factor binding protein 2
FNIP1 folliculin interacting protein 1
FOXL1 forkhead box L1
FOXN2 forkhead box N2
FZD6 frizzled class receptor 6
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GHR growth hormone receptor
GJB7 gap junction protein, beta 7, 25kDa
GLCE glucuronic acid epimerase
GLO1 glyoxalase I
GLTP glycolipid transfer protein
GLTSCR1L GLTSCR1-like
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNB5 guanine nucleotide binding protein (G protein), beta 5
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR176 G protein-coupled receptor 176
GPR63 G protein-coupled receptor 63
GPRIN1 G protein regulated inducer of neurite outgrowth 1
GRPEL2 GrpE-like 2, mitochondrial (E. coli)
GSTM2 glutathione S-transferase mu 2 (muscle)
HDAC4 histone deacetylase 4
HEATR5B HEAT repeat containing 5B
HIAT1 hippocampus abundant transcript 1
HMGXB4 HMG box domain containing 4
HS6ST3 heparan sulfate 6-O-sulfotransferase 3
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
ICK intestinal cell (MAK-like) kinase
IGSF3 immunoglobulin superfamily, member 3
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IPO7 importin 7
IQGAP1 IQ motif containing GTPase activating protein 1
IREB2 iron-responsive element binding protein 2
IRS2 insulin receptor substrate 2
ITGB8 integrin, beta 8
ITPKB inositol-trisphosphate 3-kinase B
JAKMIP2 janus kinase and microtubule interacting protein 2
JUP junction plakoglobin
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KCTD20 potassium channel tetramerization domain containing 20
KDM3A lysine (K)-specific demethylase 3A
KDM7A lysine (K)-specific demethylase 7A
KIAA0368 KIAA0368
KIAA1033 KIAA1033
KIAA1671 KIAA1671
KIAA1715 KIAA1715
KIDINS220 kinase D-interacting substrate, 220kDa
KIF14 kinesin family member 14
KITLG KIT ligand
KLF3 Kruppel-like factor 3 (basic)
KLHL4 kelch-like family member 4
KPRP keratinocyte proline-rich protein
KRTAP9-2 keratin associated protein 9-2
KRTAP9-4 keratin associated protein 9-4
KRTAP9-8 keratin associated protein 9-8
KYNU kynureninase
LARP4 La ribonucleoprotein domain family, member 4
LCE3C late cornified envelope 3C
LCE3D late cornified envelope 3D
LCE3E late cornified envelope 3E
LGSN lengsin, lens protein with glutamine synthetase domain
LIMS1 LIM and senescent cell antigen-like domains 1
LINC01548 long intergenic non-protein coding RNA 1548
LOC100130264 uncharacterized LOC100130264
LPAR1 lysophosphatidic acid receptor 1
LPP LIM domain containing preferred translocation partner in lipoma
LRP12 low density lipoprotein receptor-related protein 12
LRP1B low density lipoprotein receptor-related protein 1B
LRRC1 leucine rich repeat containing 1
LRRTM4 leucine rich repeat transmembrane neuronal 4
LYRM2 LYR motif containing 2
MAN1A2 mannosidase, alpha, class 1A, member 2
MANEA mannosidase, endo-alpha
MAP2 microtubule-associated protein 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK13 mitogen-activated protein kinase 13
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
MCM3 minichromosome maintenance complex component 3
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MED20 mediator complex subunit 20
MEGF10 multiple EGF-like-domains 10
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MIEF1 mitochondrial elongation factor 1
MIP major intrinsic protein of lens fiber
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MMS22L MMS22-like, DNA repair protein
MRAP2 melanocortin 2 receptor accessory protein 2
MTDH metadherin
MUT methylmalonyl CoA mutase
MYO5A myosin VA (heavy chain 12, myoxin)
NAMPT nicotinamide phosphoribosyltransferase
NBR1 neighbor of BRCA1 gene 1
NCKAP1 NCK-associated protein 1
NCOA1 nuclear receptor coactivator 1
NDRG4 NDRG family member 4
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
NEFL neurofilament, light polypeptide
NF2 neurofibromin 2 (merlin)
NFYA nuclear transcription factor Y, alpha
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1
NOTCH3 notch 3
NPR3 natriuretic peptide receptor 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUP50 nucleoporin 50kDa
OARD1 O-acyl-ADP-ribose deacylase 1
ODC1 ornithine decarboxylase 1
OR11H4 olfactory receptor, family 11, subfamily H, member 4
OR1L4 olfactory receptor, family 1, subfamily L, member 4
OR6C70 olfactory receptor, family 6, subfamily C, member 70
ORC3 origin recognition complex, subunit 3
PARVB parvin, beta
PAWR PRKC, apoptosis, WT1, regulator
PCDHB16 protocadherin beta 16
PCDHB6 protocadherin beta 6
PCDHGB6 protocadherin gamma subfamily B, 6
PCF11 PCF11 cleavage and polyadenylation factor subunit
PCLO piccolo presynaptic cytomatrix protein
PDCL phosducin-like
PGAP1 post-GPI attachment to proteins 1
PHC3 polyhomeotic homolog 3 (Drosophila)
PHF20L1 PHD finger protein 20-like 1
PHF3 PHD finger protein 3
PHIP pleckstrin homology domain interacting protein
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PKP1 plakophilin 1
PLS3 plastin 3
PM20D2 peptidase M20 domain containing 2
PNPLA1 patatin-like phospholipase domain containing 1
PPIG peptidylprolyl isomerase G (cyclophilin G)
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae)
PRDM13 PR domain containing 13
PRKCA protein kinase C, alpha
PRKD1 protein kinase D1
PRKX protein kinase, X-linked
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PSD3 pleckstrin and Sec7 domain containing 3
PTAR1 protein prenyltransferase alpha subunit repeat containing 1
PTBP3 polypyrimidine tract binding protein 3
PTDSS1 phosphatidylserine synthase 1
PTH2R parathyroid hormone 2 receptor
PTPN20 protein tyrosine phosphatase, non-receptor type 20
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PTPRD protein tyrosine phosphatase, receptor type, D
PUM2 pumilio RNA-binding family member 2
PURB purine-rich element binding protein B
PYGO1 pygopus family PHD finger 1
QSER1 glutamine and serine rich 1
RAB10 RAB10, member RAS oncogene family
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RAD23B RAD23 homolog B (S. cerevisiae)
RAD50 RAD50 homolog (S. cerevisiae)
RALB v-ral simian leukemia viral oncogene homolog B
RANBP2 RAN binding protein 2
RAP2A RAP2A, member of RAS oncogene family
RARS2 arginyl-tRNA synthetase 2, mitochondrial
RBMS1 RNA binding motif, single stranded interacting protein 1
RC3H1 ring finger and CCCH-type domains 1
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RFPL1S RFPL1 antisense RNA 1
RICTOR RPTOR independent companion of MTOR, complex 2
RIF1 replication timing regulatory factor 1
RIMS2 regulating synaptic membrane exocytosis 2
RIPPLY2 ripply transcriptional repressor 2
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNF111 ring finger protein 111
RNF169 ring finger protein 169
RNGTT RNA guanylyltransferase and 5'-phosphatase
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RORA RAR-related orphan receptor A
RPL7L1 ribosomal protein L7-like 1
RPTN repetin
RRAGD Ras-related GTP binding D
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
SAYSD1 SAYSVFN motif domain containing 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SCAF11 SR-related CTD-associated factor 11
SCARA3 scavenger receptor class A, member 3
SCARNA20 small Cajal body-specific RNA 20
SCN9A sodium channel, voltage gated, type IX alpha subunit
SCRN3 secernin 3
SDC1 syndecan 1
SENP6 SUMO1/sentrin specific peptidase 6
SEPT10 septin 10
SHISA2 shisa family member 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC26A10 solute carrier family 26, member 10
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SLC35F3 solute carrier family 35, member F3
SLC35F5 solute carrier family 35, member F5
SLC35G1 solute carrier family 35, member G1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLFN5 schlafen family member 5
SMAD5 SMAD family member 5
SMAP1 small ArfGAP 1
SMC2 structural maintenance of chromosomes 2
SNCB synuclein, beta
SNORA40 small nucleolar RNA, H/ACA box 40
SOWAHC sosondowah ankyrin repeat domain family member C
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SPAG9 sperm associated antigen 9
SPDYA speedy/RINGO cell cycle regulator family member A
SPG11 spastic paraplegia 11 (autosomal recessive)
SPOPL speckle-type POZ protein-like
SSFA2 sperm specific antigen 2
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
ST7L suppression of tumorigenicity 7 like
STARD7 StAR-related lipid transfer (START) domain containing 7
STIM1 stromal interaction molecule 1
STK3 serine/threonine kinase 3
STK31 serine/threonine kinase 31
STRN striatin, calmodulin binding protein
STX17 syntaxin 17
STXBP5L syntaxin binding protein 5-like
SULF2 sulfatase 2
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
SYNDIG1 synapse differentiation inducing 1
SYT9 synaptotagmin IX
TAOK1 TAO kinase 1
TARBP1 TAR (HIV-1) RNA binding protein 1
TBC1D22B TBC1 domain family, member 22B
TCF20 transcription factor 20 (AR1)
TENM2 teneurin transmembrane protein 2
TG thyroglobulin
TLK1 tousled-like kinase 1
TMEM117 transmembrane protein 117
TMEM260 transmembrane protein 260
TMEM30A transmembrane protein 30A
TMEM38B transmembrane protein 38B
TMEM87A transmembrane protein 87A
TMEM87B transmembrane protein 87B
TMTC1 transmembrane and tetratricopeptide repeat containing 1
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TNNI1 troponin I type 1 (skeletal, slow)
TNPO1 transportin 1
TNRC6B trinucleotide repeat containing 6B
TP63 tumor protein p63
TRAM2 translocation associated membrane protein 2
TREML3P triggering receptor expressed on myeloid cells-like 3, pseudogene
TREML4 triggering receptor expressed on myeloid cells-like 4
TRHR thyrotropin-releasing hormone receptor
TRIM33 tripartite motif containing 33
TROVE2 TROVE domain family, member 2
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TTC21B tetratricopeptide repeat domain 21B
TUBGCP4 tubulin, gamma complex associated protein 4
TXNRD1 thioredoxin reductase 1
UBE2H ubiquitin-conjugating enzyme E2H
UBE3A ubiquitin protein ligase E3A
UBE3C ubiquitin protein ligase E3C
UBQLN2 ubiquilin 2
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative)
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UBXN4 UBX domain protein 4
UFL1 UFM1-specific ligase 1
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UNC119B unc-119 homolog B (C. elegans)
UPK1B uroplakin 1B
USP45 ubiquitin specific peptidase 45
VPS13B vacuolar protein sorting 13 homolog B (yeast)
VWA8 von Willebrand factor A domain containing 8
WASL Wiskott-Aldrich syndrome-like
WDR72 WD repeat domain 72
WISP1 WNT1 inducible signaling pathway protein 1
WNT11 wingless-type MMTV integration site family, member 11
WNT5A wingless-type MMTV integration site family, member 5A
WRN Werner syndrome, RecQ helicase-like
WSB2 WD repeat and SOCS box containing 2
YIPF4 Yip1 domain family, member 4
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB26 zinc finger and BTB domain containing 26
ZBTB41 zinc finger and BTB domain containing 41
ZBTB43 zinc finger and BTB domain containing 43
ZC3HAV1L zinc finger CCCH-type, antiviral 1-like
ZCCHC6 zinc finger, CCHC domain containing 6
ZDHHC2 zinc finger, DHHC-type containing 2
ZFAND3 zinc finger, AN1-type domain 3
ZFX zinc finger protein, X-linked
ZIC5 Zic family member 5
ZNF217 zinc finger protein 217
ZNF292 zinc finger protein 292
ZNF367 zinc finger protein 367
ZNF451 zinc finger protein 451
ZNF624 zinc finger protein 624
ZNF746 zinc finger protein 746
ZNF770 zinc finger protein 770
ZNF800 zinc finger protein 800
ZXDB zinc finger, X-linked, duplicated B

low expression

Symbol Name
ABHD16A abhydrolase domain containing 16A
ADPRHL2 ADP-ribosylhydrolase like 2
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
ESD esterase D
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
PEX14 peroxisomal biogenesis factor 14
RING1 ring finger protein 1