Lung squamous cell carcinoma_LUSC_TCGA-56-7222-01A-11R-2045-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

441 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-56-7222-01A-11R-2045-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
AATF apoptosis antagonizing transcription factor
ABHD17C abhydrolase domain containing 17C
ABI1 abl-interactor 1
ADORA2B adenosine A2b receptor
AEBP2 AE binding protein 2
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AGPS alkylglycerone phosphate synthase
AHR aryl hydrocarbon receptor
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALG10 ALG10, alpha-1,2-glucosyltransferase
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
ANKRD12 ankyrin repeat domain 12
ANKRD26 ankyrin repeat domain 26
ANLN anillin, actin binding protein
ANXA2P1 annexin A2 pseudogene 1
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ARHGAP11A Rho GTPase activating protein 11A
ARHGAP12 Rho GTPase activating protein 12
ARHGAP21 Rho GTPase activating protein 21
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
ARL4C ADP-ribosylation factor-like 4C
ARL5B ADP-ribosylation factor-like 5B
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ARR3 arrestin 3, retinal (X-arrestin)
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASUN asunder spermatogenesis regulator
ATAD2 ATPase family, AAA domain containing 2
ATL2 atlastin GTPase 2
AURKB aurora kinase B
AXIN1 axin 1
BARD1 BRCA1 associated RING domain 1
BCAR3 breast cancer anti-estrogen resistance 3
BCAS4 breast carcinoma amplified sequence 4
BLM Bloom syndrome, RecQ helicase-like
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted
BMS1 BMS1 ribosome biogenesis factor
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
BRIX1 BRX1, biogenesis of ribosomes
BTBD1 BTB (POZ) domain containing 1
BTBD16 BTB (POZ) domain containing 16
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C10ORF111 chromosome 10 open reading frame 111
C1QTNF8 C1q and tumor necrosis factor related protein 8
C2ORF69 chromosome 2 open reading frame 69
C8ORF74 chromosome 8 open reading frame 74
CA12 carbonic anhydrase XII
CA14 carbonic anhydrase XIV
CAB39 calcium binding protein 39
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CASC5 cancer susceptibility candidate 5
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CBWD5 COBW domain containing 5
CCDC18 coiled-coil domain containing 18
CCDC91 coiled-coil domain containing 91
CCHCR1 coiled-coil alpha-helical rod protein 1
CCR10 chemokine (C-C motif) receptor 10
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CD109 CD109 molecule
CDC27 cell division cycle 27
CDH8 cadherin 8, type 2
CDR2 cerebellar degeneration-related protein 2, 62kDa
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CERS6 ceramide synthase 6
CKAP2L cytoskeleton associated protein 2-like
CLEC18A C-type lectin domain family 18, member A
CLEC18B C-type lectin domain family 18, member B
CLEC18C C-type lectin domain family 18, member C
CLMN calmin (calponin-like, transmembrane)
CLTC clathrin, heavy chain (Hc)
CMTM6 CKLF-like MARVEL transmembrane domain containing 6
COL4A6 collagen, type IV, alpha 6
COPG2 coatomer protein complex, subunit gamma 2
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
CPA1 carboxypeptidase A1 (pancreatic)
CPD carboxypeptidase D
CPLX3 complexin 3
CPNE1 copine I
CREB1 cAMP responsive element binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRLF1 cytokine receptor-like factor 1
CT62 cancer/testis antigen 62
CTNS cystinosin, lysosomal cystine transporter
CTRB2 chymotrypsinogen B2
CTTNBP2NL CTTNBP2 N-terminal like
CUEDC1 CUE domain containing 1
CWC22 CWC22 spliceosome-associated protein
DCLRE1C DNA cross-link repair 1C
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DEK DEK proto-oncogene
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNASE1L1 deoxyribonuclease I-like 1
DNM1L dynamin 1-like
DPP8 dipeptidyl-peptidase 8
DPYD dihydropyrimidine dehydrogenase
DTWD1 DTW domain containing 1
DUSP6 dual specificity phosphatase 6
DUSP9 dual specificity phosphatase 9
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFR3A EFR3 homolog A (S. cerevisiae)
EGR4 early growth response 4
EIF3CL eukaryotic translation initiation factor 3, subunit C-like
EIF3J eukaryotic translation initiation factor 3, subunit J
EIF6 eukaryotic translation initiation factor 6
ELOVL5 ELOVL fatty acid elongase 5
EMC1 ER membrane protein complex subunit 1
ENAH enabled homolog (Drosophila)
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2
ERGIC2 ERGIC and golgi 2
ERGIC3 ERGIC and golgi 3
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
EXOC5 exocyst complex component 5
FAM181A family with sequence similarity 181, member A
FAM181A-AS1 FAM181A antisense RNA 1
FAM208B family with sequence similarity 208, member B
FAM3C family with sequence similarity 3, member C
FAM64A family with sequence similarity 64, member A
FAM72A family with sequence similarity 72, member A
FAM72B family with sequence similarity 72, member B
FAM72D family with sequence similarity 72, member D
FAM91A1 family with sequence similarity 91, member A1
FAM98B family with sequence similarity 98, member B
FANCM Fanconi anemia, complementation group M
FCF1 FCF1 rRNA-processing protein
FEM1B fem-1 homolog b (C. elegans)
FGFR1OP2 FGFR1 oncogene partner 2
FIBCD1 fibrinogen C domain containing 1
FKBP10 FK506 binding protein 10, 65 kDa
FMNL2 formin-like 2
FMR1 fragile X mental retardation 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXC1 forkhead box C1
FOXJ2 forkhead box J2
FRMD5 FERM domain containing 5
FYB FYN binding protein
G0S2 G0/G1 switch 2
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GINS1 GINS complex subunit 1 (Psf1 homolog)
GJC2 gap junction protein, gamma 2, 47kDa
GLB1L galactosidase, beta 1-like
GMDS GDP-mannose 4,6-dehydratase
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPATCH11 G patch domain containing 11
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR153 G protein-coupled receptor 153
GPR39 G protein-coupled receptor 39
GPSM2 G-protein signaling modulator 2
GTPBP4 GTP binding protein 4
GUSBP2 glucuronidase, beta pseudogene 2
H19 H19, imprinted maternally expressed transcript (non-protein coding)
H3F3B H3 histone, family 3B (H3.3B)
HACD2 3-hydroxyacyl-CoA dehydratase 2
HAUS2 HAUS augmin-like complex, subunit 2
HCG18 HLA complex group 18 (non-protein coding)
HEBP1 heme binding protein 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H1A histone cluster 1, H1a
HIST1H4A histone cluster 1, H4a
HMGN2P46 high mobility group nucleosomal binding domain 2 pseudogene 46
HN1L hematological and neurological expressed 1-like
HNRNPF heterogeneous nuclear ribonucleoprotein F
HP haptoglobin
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6
IER3 immediate early response 3
IFNL1 interferon, lambda 1
IFNL2 interferon, lambda 2
INTS2 integrator complex subunit 2
IQGAP1 IQ motif containing GTPase activating protein 1
IRS1 insulin receptor substrate 1
ITCH itchy E3 ubiquitin protein ligase
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
KDM1B lysine (K)-specific demethylase 1B
KHDC1L KH homology domain containing 1-like
KIF14 kinesin family member 14
KIF20B kinesin family member 20B
KIF23 kinesin family member 23
KIF5B kinesin family member 5B
KITLG KIT ligand
KLHL38 kelch-like family member 38
KPNB1 karyopherin (importin) beta 1
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
KRT23 keratin 23, type I
KRTAP4-8 keratin associated protein 4-8
KTN1 kinectin 1 (kinesin receptor)
L1CAM L1 cell adhesion molecule
LAMA1 laminin, alpha 1
LAMB3 laminin, beta 3
LDHB lactate dehydrogenase B
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LINC00521 long intergenic non-protein coding RNA 521
LINC01588 long intergenic non-protein coding RNA 1588
LMAN1L lectin, mannose-binding, 1 like
LOC100132111 uncharacterized LOC100132111
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3
LRRC16A leucine rich repeat containing 16A
LRRC57 leucine rich repeat containing 57
M6PR mannose-6-phosphate receptor (cation dependent)
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MAP7 microtubule-associated protein 7
MAPK6 mitogen-activated protein kinase 6
MAPKBP1 mitogen-activated protein kinase binding protein 1
MASTL microtubule associated serine/threonine kinase-like
MB21D1 Mab-21 domain containing 1
MCM10 minichromosome maintenance complex component 10
MDC1 mediator of DNA-damage checkpoint 1
MED21 mediator complex subunit 21
MED24 mediator complex subunit 24
MESTIT1 MEST intronic transcript 1, antisense RNA
METRN meteorin, glial cell differentiation regulator
MIOX myo-inositol oxygenase
MIS12 MIS12 kinetochore complex component
MISP mitotic spindle positioning
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MORF4 mortality factor 4 (pseudogene)
MRPS35 mitochondrial ribosomal protein S35
MSL3P1 male-specific lethal 3 homolog (Drosophila) pseudogene 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO1D myosin ID
MYO1E myosin IE
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NCAPD2 non-SMC condensin I complex, subunit D2
NCL nucleolin
NET1 neuroepithelial cell transforming 1
NFIA nuclear factor I/A
NFS1 NFS1 cysteine desulfurase
NGFR nerve growth factor receptor
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NKX1-2 NK1 homeobox 2
NMUR2 neuromedin U receptor 2
NODAL nodal growth differentiation factor
NPTN neuroplastin
NR5A1 nuclear receptor subfamily 5, group A, member 1
NRM nurim (nuclear envelope membrane protein)
NSUN6 NOP2/Sun domain family, member 6
NT5DC3 5'-nucleotidase domain containing 3
NUAK1 NUAK family, SNF1-like kinase, 1
NUBPL nucleotide binding protein-like
NUP153 nucleoporin 153kDa
NUSAP1 nucleolar and spindle associated protein 1
OIP5 Opa interacting protein 5
OR2D3 olfactory receptor, family 2, subfamily D, member 3
OSBPL8 oxysterol binding protein-like 8
P3H3 prolyl 3-hydroxylase 3
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PANK2 pantothenate kinase 2
PAQR4 progestin and adipoQ receptor family member IV
PAWR PRKC, apoptosis, WT1, regulator
PCDHGB5 protocadherin gamma subfamily B, 5
PDIA2 protein disulfide isomerase family A, member 2
PDIA3 protein disulfide isomerase family A, member 3
PDIA3P1 protein disulfide isomerase family A, member 3 pseudogene 1
PDIA6 protein disulfide isomerase family A, member 6
PDPK1 3-phosphoinositide dependent protein kinase 1
PF4V1 platelet factor 4 variant 1
PHF20 PHD finger protein 20
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHYH phytanoyl-CoA 2-hydroxylase
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PKP2 plakophilin 2
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCD3 phospholipase C, delta 3
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLIN4 perilipin 4
PLXNA2 plexin A2
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PPP4R1 protein phosphatase 4, regulatory subunit 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRM3 protamine 3
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PRR11 proline rich 11
PRTFDC1 phosphoribosyl transferase domain containing 1
PSORS1C3 psoriasis susceptibility 1 candidate 3 (non-protein coding)
PTBP3 polypyrimidine tract binding protein 3
PTCHD2 patched domain containing 2
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTPRK protein tyrosine phosphatase, receptor type, K
PTX4 pentraxin 4, long
PXDN peroxidasin
RALY RALY heterogeneous nuclear ribonucleoprotein
RBBP8 retinoblastoma binding protein 8
RBM17 RNA binding motif protein 17
RBMS1 RNA binding motif, single stranded interacting protein 1
REP15 RAB15 effector protein
REPS2 RALBP1 associated Eps domain containing 2
RERG RAS-like, estrogen-regulated, growth inhibitor
RGS17 regulator of G-protein signaling 17
RICTOR RPTOR independent companion of MTOR, complex 2
RIN2 Ras and Rab interactor 2
RIPPLY2 ripply transcriptional repressor 2
RND3 Rho family GTPase 3
RNF111 ring finger protein 111
RNF144B ring finger protein 144B
RNMT RNA (guanine-7-) methyltransferase
RNPS1 RNA binding protein S1, serine-rich domain
RNU11 RNA, U11 small nuclear
RPAP3 RNA polymerase II associated protein 3
RPE ribulose-5-phosphate-3-epimerase
SASS6 spindle assembly 6 homolog (C. elegans)
SAV1 salvador family WW domain containing protein 1
SCARNA9L small Cajal body-specific RNA 9-like
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEPHS1 selenophosphate synthetase 1
SEPT2 septin 2
SEPT9 septin 9
SERBP1 SERPINE1 mRNA binding protein 1
SH2D5 SH2 domain containing 5
SIKE1 suppressor of IKBKE 1
SIX2 SIX homeobox 2
SIX4 SIX homeobox 4
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC22A23 solute carrier family 22, member 23
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC38A1 solute carrier family 38, member 1
SLK STE20-like kinase
SNAI2 snail family zinc finger 2
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SNORA21 small nucleolar RNA, H/ACA box 21
SNORA31 small nucleolar RNA, H/ACA box 31
SNORA40 small nucleolar RNA, H/ACA box 40
SNORA52 small nucleolar RNA, H/ACA box 52
SNORA70 small nucleolar RNA, H/ACA box 70
SNORA71A small nucleolar RNA, H/ACA box 71A
SNORA80A small nucleolar RNA, H/ACA box 80A
SNORA81 small nucleolar RNA, H/ACA box 81
SNORA84 small nucleolar RNA, H/ACA box 84
SNORD89 small nucleolar RNA, C/D box 89
SP4 Sp4 transcription factor
SPAG1 sperm associated antigen 1
SPAG9 sperm associated antigen 9
SPDYC speedy/RINGO cell cycle regulator family member C
SPIRE1 spire-type actin nucleation factor 1
SRL sarcalumenin
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
SSFA2 sperm specific antigen 2
SSTR5 somatostatin receptor 5
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STEAP3 STEAP family member 3, metalloreductase
STK38L serine/threonine kinase 38 like
STK39 serine threonine kinase 39
STXBP3 syntaxin binding protein 3
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TAS2R43 taste receptor, type 2, member 43
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TEAD4 TEA domain family member 4
THAP10 THAP domain containing 10
THOC6 THO complex 6
THSD4 thrombospondin, type I, domain containing 4
TIPIN TIMELESS interacting protein
TM7SF3 transmembrane 7 superfamily member 3
TMEM167B transmembrane protein 167B
TMEM200B transmembrane protein 200B
TMEM209 transmembrane protein 209
TMEM65 transmembrane protein 65
TMEM87A transmembrane protein 87A
TMEM8A transmembrane protein 8A
TMEM95 transmembrane protein 95
TMOD3 tropomodulin 3 (ubiquitous)
TMX1 thioredoxin-related transmembrane protein 1
TNC tenascin C
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPBG trophoblast glycoprotein
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
TRAM2 translocation associated membrane protein 2
TRERF1 transcriptional regulating factor 1
TRIM26 tripartite motif containing 26
TRIM47 tripartite motif containing 47
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase
TRMT6 tRNA methyltransferase 6
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSKS testis-specific serine kinase substrate
TSPAN9 tetraspanin 9
TTC27 tetratricopeptide repeat domain 27
TUBGCP4 tubulin, gamma complex associated protein 4
TVP23C trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
TXNDC17 thioredoxin domain containing 17
UBE2H ubiquitin-conjugating enzyme E2H
UBE2I ubiquitin-conjugating enzyme E2I
UBE3A ubiquitin protein ligase E3A
UBN1 ubinuclein 1
UBR1 ubiquitin protein ligase E3 component n-recognin 1
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative)
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
USP3 ubiquitin specific peptidase 3
USP31 ubiquitin specific peptidase 31
USP8 ubiquitin specific peptidase 8
VEZF1 vascular endothelial zinc finger 1
WAC WW domain containing adaptor with coiled-coil
WASF2 WAS protein family, member 2
WASL Wiskott-Aldrich syndrome-like
WBP11 WW domain binding protein 11
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR43 WD repeat domain 43
WDR47 WD repeat domain 47
WDR89 WD repeat domain 89
WNK1 WNK lysine deficient protein kinase 1
WNT3A wingless-type MMTV integration site family, member 3A
WNT4 wingless-type MMTV integration site family, member 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRN2 5'-3' exoribonuclease 2
YBX3P1 Y box binding protein 3 pseudogene 1
YME1L1 YME1-like 1 ATPase
YOD1 YOD1 deubiquitinase
ZCCHC12 zinc finger, CCHC domain containing 12
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF665 zinc finger protein 665
ZNF75A zinc finger protein 75a
ZNF880 zinc finger protein 880
ZNHIT6 zinc finger, HIT-type containing 6
ZSCAN29 zinc finger and SCAN domain containing 29
ZSCAN9 zinc finger and SCAN domain containing 9
ZWILCH zwilch kinetochore protein
ZZZ3 zinc finger, ZZ-type containing 3

low expression

Symbol Name
C12ORF43 chromosome 12 open reading frame 43
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
RNF10 ring finger protein 10
STAT5B signal transducer and activator of transcription 5B
TIGD6 tigger transposable element derived 6
WDR45 WD repeat domain 45