Lung squamous cell carcinoma_LUSC_TCGA-56-5897-01A-11R-1635-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

250 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-56-5897-01A-11R-1635-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACKR3 atypical chemokine receptor 3
ACTA2 actin, alpha 2, smooth muscle, aorta
ACVR1 activin A receptor, type I
ADAM12 ADAM metallopeptidase domain 12
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADORA3 adenosine A3 receptor
AEBP1 AE binding protein 1
AGFG1 ArfGAP with FG repeats 1
ANGPTL2 angiopoietin-like 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANTXR1 anthrax toxin receptor 1
ARHGAP32 Rho GTPase activating protein 32
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ASPH aspartate beta-hydroxylase
ATP10D ATPase, class V, type 10D
ATXN1 ataxin 1
BGN biglycan
BHLHE22 basic helix-loop-helix family, member e22
BMP8A bone morphogenetic protein 8a
C5ORF52 chromosome 5 open reading frame 52
CAB39 calcium binding protein 39
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CCDC80 coiled-coil domain containing 80
CCL11 chemokine (C-C motif) ligand 11
CCNYL1 cyclin Y-like 1
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDYL chromodomain protein, Y-like
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CEMIP cell migration inducing protein, hyaluronan binding
CENPW centromere protein W
CES1P1 carboxylesterase 1 pseudogene 1
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CILP2 cartilage intermediate layer protein 2
CLCN1 chloride channel, voltage-sensitive 1
COL11A1 collagen, type XI, alpha 1
COL12A1 collagen, type XII, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
COL6A3 collagen, type VI, alpha 3
COL8A1 collagen, type VIII, alpha 1
COL8A2 collagen, type VIII, alpha 2
COMP cartilage oligomeric matrix protein
CORIN corin, serine peptidase
CPZ carboxypeptidase Z
CSMD2 CUB and Sushi multiple domains 2
CTSK cathepsin K
CYFIP1 cytoplasmic FMR1 interacting protein 1
CYLD cylindromatosis (turban tumor syndrome)
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DAB2IP DAB2 interacting protein
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DPT dermatopontin
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
EHBP1L1 EH domain binding protein 1-like 1
ELF1 E74-like factor 1 (ets domain transcription factor)
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EMILIN1 elastin microfibril interfacer 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ESR1 estrogen receptor 1
EVC Ellis van Creveld protein
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM101A family with sequence similarity 101, member A
FAM109B family with sequence similarity 109, member B
FAM114A1 family with sequence similarity 114, member A1
FAM131B family with sequence similarity 131, member B
FAM225B family with sequence similarity 225, member B (non-protein coding)
FAM74A4 family with sequence similarity 74, member A4
FAM83A family with sequence similarity 83, member A
FAT1 FAT atypical cadherin 1
FBLIM1 filamin binding LIM protein 1
FBN1 fibrillin 1
FERMT1 fermitin family member 1
FNDC1 fibronectin type III domain containing 1
FOLR2 folate receptor 2 (fetal)
FOXO1 forkhead box O1
FRRS1 ferric-chelate reductase 1
GAS7 growth arrest-specific 7
GIGYF2 GRB10 interacting GYF protein 2
GJB2 gap junction protein, beta 2, 26kDa
GJB6 gap junction protein, beta 6, 30kDa
GORASP2 golgi reassembly stacking protein 2, 55kDa
GPR21 G protein-coupled receptor 21
GPR31 G protein-coupled receptor 31
GPR68 G protein-coupled receptor 68
GREM1 gremlin 1, DAN family BMP antagonist
GTDC1 glycosyltransferase-like domain containing 1
GXYLT2 glucoside xylosyltransferase 2
HDLBP high density lipoprotein binding protein
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HTRA3 HtrA serine peptidase 3
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IRS1 insulin receptor substrate 1
ISLR immunoglobulin superfamily containing leucine-rich repeat
ISM1 isthmin 1, angiogenesis inhibitor
ITGA11 integrin, alpha 11
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAV integrin, alpha V
ITGB6 integrin, beta 6
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KIAA0513 KIAA0513
KIF26B kinesin family member 26B
KLF13 Kruppel-like factor 13
KLF7 Kruppel-like factor 7 (ubiquitous)
KYNU kynureninase
LACC1 laccase (multicopper oxidoreductase) domain containing 1
LAX1 lymphocyte transmembrane adaptor 1
LINC00207 long intergenic non-protein coding RNA 207
LINC00346 long intergenic non-protein coding RNA 346
LOC100130264 uncharacterized LOC100130264
LOC100132111 uncharacterized LOC100132111
LOC221122 uncharacterized LOC221122
LOC401463 uncharacterized LOC401463
LRP1 low density lipoprotein receptor-related protein 1
LRRC15 leucine rich repeat containing 15
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK10 mitogen-activated protein kinase 10
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
MBOAT2 membrane bound O-acyltransferase domain containing 2
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1
MLXIP MLX interacting protein
MMP2 matrix metallopeptidase 2
MPPED2 metallophosphoesterase domain containing 2
MRVI1 murine retrovirus integration site 1 homolog
MSC musculin
MXRA5 matrix-remodelling associated 5
N4BP1 NEDD4 binding protein 1
NAP1L4 nucleosome assembly protein 1-like 4
NBL1 neuroblastoma 1, DAN family BMP antagonist
NBPF10 neuroblastoma breakpoint family, member 10
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1
NID2 nidogen 2 (osteonidogen)
NRG4 neuregulin 4
NRIP1 nuclear receptor interacting protein 1
NSG1 neuron specific gene family member 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NWD2 NACHT and WD repeat domain containing 2
NXPE4 neurexophilin and PC-esterase domain family, member 4
OAF OAF homolog (Drosophila)
OMD osteomodulin
OR10A6 olfactory receptor, family 10, subfamily A, member 6 (gene/pseudogene)
OR4F21 olfactory receptor, family 4, subfamily F, member 21
OR52E2 olfactory receptor, family 52, subfamily E, member 2
PALLD palladin, cytoskeletal associated protein
PARVB parvin, beta
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDGFRL platelet-derived growth factor receptor-like
PDLIM5 PDZ and LIM domain 5
PEX26 peroxisomal biogenesis factor 26
PICALM phosphatidylinositol binding clathrin assembly protein
PITRM1 pitrilysin metallopeptidase 1
PLA2G5 phospholipase A2, group V
PLEC plectin
PMEL premelanosome protein
PODN podocan
POU2AF1 POU class 2 associating factor 1
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma
PRDM1 PR domain containing 1, with ZNF domain
PRKG1 protein kinase, cGMP-dependent, type I
PROM2 prominin 2
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PYGB phosphorylase, glycogen; brain
RAB43 RAB43, member RAS oncogene family
RAP2A RAP2A, member of RAS oncogene family
RCVRN recoverin
RGS12 regulator of G-protein signaling 12
RHBDD1 rhomboid domain containing 1
RNF4 ring finger protein 4
RNF6 ring finger protein (C3H2C3 type) 6
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SBF1 SET binding factor 1
SCT secretin
SEC23IP SEC23 interacting protein
SEC24B SEC24 family member B
SEC24D SEC24 family member D
SETD7 SET domain containing (lysine methyltransferase) 7
SFRP2 secreted frizzled-related protein 2
SFRP4 secreted frizzled-related protein 4
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SH3PXD2A SH3 and PX domains 2A
SH3PXD2B SH3 and PX domains 2B
SIGLEC8 sialic acid binding Ig-like lectin 8
SLAMF8 SLAM family member 8
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNORA41 small nucleolar RNA, H/ACA box 41
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SSC5D scavenger receptor cysteine rich family, 5 domains
STK24 serine/threonine kinase 24
SULF1 sulfatase 1
SYT7 synaptotagmin VII
TAGLN transgelin
TAS2R60 taste receptor, type 2, member 60
TBC1D14 TBC1 domain family, member 14
TEF thyrotrophic embryonic factor
THBS2 thrombospondin 2
THSD1 thrombospondin, type I, domain containing 1
THY1 Thy-1 cell surface antigen
TIMP2 TIMP metallopeptidase inhibitor 2
TLK1 tousled-like kinase 1
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMCO5A transmembrane and coiled-coil domains 5A
TMEM110 transmembrane protein 110
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TPM4 tropomyosin 4
TPST1 tyrosylprotein sulfotransferase 1
TRIB2 tribbles pseudokinase 2
TRIP12 thyroid hormone receptor interactor 12
TSKU tsukushi, small leucine rich proteoglycan
TSPAN7 tetraspanin 7
TTC22 tetratricopeptide repeat domain 22
TUBA4A tubulin, alpha 4a
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
UNC5B unc-5 homolog B (C. elegans)
USB1 U6 snRNA biogenesis 1
VCAN versican
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae)
VWA8 von Willebrand factor A domain containing 8
WDR1 WD repeat domain 1
WNT2 wingless-type MMTV integration site family member 2
WSB2 WD repeat and SOCS box containing 2
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
XYLT1 xylosyltransferase I
ZC3H13 zinc finger CCCH-type containing 13
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF365 zinc finger protein 365
ZNF469 zinc finger protein 469
ZNF827 zinc finger protein 827
ZSWIM4 zinc finger, SWIM-type containing 4
ZYX zyxin

low expression

Symbol Name
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3