Lung squamous cell carcinoma_LUSC_TCGA-51-4079-01A-01R-1100-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

273 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-51-4079-01A-01R-1100-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABHD17B abhydrolase domain containing 17B
ABHD3 abhydrolase domain containing 3
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ADAM17 ADAM metallopeptidase domain 17
ADM adrenomedullin
ADORA2B adenosine A2b receptor
AGFG1 ArfGAP with FG repeats 1
AHR aryl hydrocarbon receptor
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase
ALOX12B arachidonate 12-lipoxygenase, 12R type
ANKRD32 ankyrin repeat domain 32
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
APTX aprataxin
ARL4D ADP-ribosylation factor-like 4D
ARPC5L actin related protein 2/3 complex, subunit 5-like
ARSK arylsulfatase family, member K
ATF6 activating transcription factor 6
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1
ATRN attractin
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCL10 B-cell CLL/lymphoma 10
BICD2 bicaudal D homolog 2 (Drosophila)
BTBD1 BTB (POZ) domain containing 1
C16ORF72 chromosome 16 open reading frame 72
C18ORF8 chromosome 18 open reading frame 8
C1ORF177 chromosome 1 open reading frame 177
C3ORF67 chromosome 3 open reading frame 67
C9ORF78 chromosome 9 open reading frame 78
CAST calpastatin
CBR1 carbonyl reductase 1
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CDK9 cyclin-dependent kinase 9
CEP97 centrosomal protein 97kDa
CES1P1 carboxylesterase 1 pseudogene 1
CLDN20 claudin 20
CLDN8 claudin 8
CLEC3A C-type lectin domain family 3, member A
CNOT7 CCR4-NOT transcription complex, subunit 7
COMMD1 copper metabolism (Murr1) domain containing 1
CORO1C coronin, actin binding protein, 1C
CREG1 cellular repressor of E1A-stimulated genes 1
CTDNEP1 CTD nuclear envelope phosphatase 1
CXORF51A chromosome X open reading frame 51A
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF10 DDB1 and CUL4 associated factor 10
DCAF12 DDB1 and CUL4 associated factor 12
DCAF6 DDB1 and CUL4 associated factor 6
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC25 DnaJ (Hsp40) homolog, subfamily C , member 25
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
DOLK dolichol kinase
EHBP1 EH domain binding protein 1
ELL2 elongation factor, RNA polymerase II, 2
ERAP1 endoplasmic reticulum aminopeptidase 1
ERI1 exoribonuclease 1
ERP44 endoplasmic reticulum protein 44
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1
FADS1 fatty acid desaturase 1
FAM102A family with sequence similarity 102, member A
FAM120A family with sequence similarity 120A
FAM120AOS family with sequence similarity 120A opposite strand
FAM122A family with sequence similarity 122A
FAM161A family with sequence similarity 161, member A
FAM172A family with sequence similarity 172, member A
FAM206A family with sequence similarity 206, member A
FAM69A family with sequence similarity 69, member A
FASTKD5 FAST kinase domains 5
FBXO36 F-box protein 36
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FGFBP1 fibroblast growth factor binding protein 1
FLAD1 flavin adenine dinucleotide synthetase 1
FOPNL FGFR1OP N-terminal like
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GBP6 guanylate binding protein family, member 6
GCLC glutamate-cysteine ligase, catalytic subunit
GFOD1 glucose-fructose oxidoreductase domain containing 1
GOLPH3L golgi phosphoprotein 3-like
GPR107 G protein-coupled receptor 107
GPRC5D G protein-coupled receptor, class C, group 5, member D
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
GSR glutathione reductase
GSTM4 glutathione S-transferase mu 4
GSTTP1 glutathione S-transferase theta pseudogene 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HACL1 2-hydroxyacyl-CoA lyase 1
HAS3 hyaluronan synthase 3
HIATL1 hippocampus abundant transcript-like 1
HNRNPK heterogeneous nuclear ribonucleoprotein K
HRASLS HRAS-like suppressor
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IARS isoleucyl-tRNA synthetase
IGFBP3 insulin-like growth factor binding protein 3
IMPACT impact RWD domain protein
INIP INTS3 and NABP interacting protein
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ISCA1 iron-sulfur cluster assembly 1
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
ISPD isoprenoid synthase domain containing
KCTD9 potassium channel tetramerization domain containing 9
KIAA0825 KIAA0825
KLF4 Kruppel-like factor 4 (gut)
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRTAP9-4 keratin associated protein 9-4
LCE3C late cornified envelope 3C
LHX2 LIM homeobox 2
LIMA1 LIM domain and actin binding 1
LNPEP leucyl/cystinyl aminopeptidase
LPAR1 lysophosphatidic acid receptor 1
LPPR1 lipid phosphate phosphatase-related protein type 1
LRRC8A leucine rich repeat containing 8 family, member A
LRRC8D leucine rich repeat containing 8 family, member D
MAPKAP1 mitogen-activated protein kinase associated protein 1
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
MARCKS myristoylated alanine-rich protein kinase C substrate
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MED27 mediator complex subunit 27
MEGF9 multiple EGF-like-domains 9
METTL15 methyltransferase like 15
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MIB1 mindbomb E3 ubiquitin protein ligase 1
MIS12 MIS12 kinetochore complex component
MRPL44 mitochondrial ribosomal protein L44
MRPL50 mitochondrial ribosomal protein L50
MSANTD3 Myb/SANT-like DNA-binding domain containing 3
MXRA7 matrix-remodelling associated 7
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NEFL neurofilament, light polypeptide
NPC1 Niemann-Pick disease, type C1
NPTN neuroplastin
NQO1 NAD(P)H dehydrogenase, quinone 1
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
NXPE3 neurexophilin and PC-esterase domain family, member 3
OLFM1 olfactomedin 1
OR1L6 olfactory receptor, family 1, subfamily L, member 6
OSBPL1A oxysterol binding protein-like 1A
OSTF1 osteoclast stimulating factor 1
OVOL1 ovo-like zinc finger 1
PANK2 pantothenate kinase 2
PAWR PRKC, apoptosis, WT1, regulator
PCDHGA10 protocadherin gamma subfamily A, 10
PCNP PEST proteolytic signal containing nuclear protein
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDCL phosducin-like
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PKM pyruvate kinase, muscle
PLCD1 phospholipase C, delta 1
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PPP6C protein phosphatase 6, catalytic subunit
PRDX6 peroxiredoxin 6
PRKG1 protein kinase, cGMP-dependent, type I
PRMT3 protein arginine methyltransferase 3
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS1 protease, serine, 1 (trypsin 1)
PRSS3P2 protease, serine, 3 pseudogene 2
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PTBP3 polypyrimidine tract binding protein 3
PTGES3 prostaglandin E synthase 3 (cytosolic)
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAB14 RAB14, member RAS oncogene family
RAB18 RAB18, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RBBP8 retinoblastoma binding protein 8
RBM18 RNA binding motif protein 18
RFESD Rieske (Fe-S) domain containing
RFT1 RFT1 homolog (S. cerevisiae)
RIOK2 RIO kinase 2
RIOK3 RIO kinase 3
RNF167 ring finger protein 167
RNMTL1 RNA methyltransferase like 1
RRM1 ribonucleotide reductase M1
S100A10 S100 calcium binding protein A10
S100A11 S100 calcium binding protein A11
S100A16 S100 calcium binding protein A16
S100A2 S100 calcium binding protein A2
SCO1 SCO1 cytochrome c oxidase assembly protein
SERBP1 SERPINE1 mRNA binding protein 1
SET SET nuclear proto-oncogene
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIRT5 sirtuin 5
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC35G1 solute carrier family 35, member G1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SPAST spastin
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SPTY2D1 SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
SRXN1 sulfiredoxin 1
SS18 synovial sarcoma translocation, chromosome 18
SSR1 signal sequence receptor, alpha
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STRBP spermatid perinuclear RNA binding protein
SURF1 surfeit 1
SURF4 surfeit 4
SWAP70 SWAP switching B-cell complex 70kDa subunit
TALDO1 transaldolase 1
TBC1D2 TBC1 domain family, member 2
TBC1D23 TBC1 domain family, member 23
TCTEX1D2 Tctex1 domain containing 2
TEX10 testis expressed 10
TFG TRK-fused gene
THBD thrombomodulin
THEMIS thymocyte selection associated
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM116 transmembrane protein 116
TMEM17 transmembrane protein 17
TMEM203 transmembrane protein 203
TMEM241 transmembrane protein 241
TMEM38B transmembrane protein 38B
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast)
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOR1A torsin family 1, member A (torsin A)
TOR1B torsin family 1, member B (torsin B)
TP63 tumor protein p63
TPM3 tropomyosin 3
TPM4 tropomyosin 4
TRIM16 tripartite motif containing 16
TRIM16L tripartite motif containing 16-like
TRIM32 tripartite motif containing 32
TRIP4 thyroid hormone receptor interactor 4
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae)
TRMT6 tRNA methyltransferase 6
TSG101 tumor susceptibility 101
TTC37 tetratricopeptide repeat domain 37
TTC39C tetratricopeptide repeat domain 39C
TTC4 tetratricopeptide repeat domain 4
TTF1 transcription termination factor, RNA polymerase I
TUFT1 tuftelin 1
TXN thioredoxin
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum)
TXNRD1 thioredoxin reductase 1
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBAP1 ubiquitin associated protein 1
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBE2K ubiquitin-conjugating enzyme E2K
UBQLN1 ubiquilin 1
UEVLD UEV and lactate/malate dehyrogenase domains
UGDH UDP-glucose 6-dehydrogenase
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UPK1B uroplakin 1B
UTP15 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae)
WWTR1 WW domain containing transcription regulator 1
YARS tyrosyl-tRNA synthetase
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZAR1L zygote arrest 1-like
ZBTB11 zinc finger and BTB domain containing 11
ZNF460 zinc finger protein 460
ZNF586 zinc finger protein 586
ZNF735 zinc finger protein 735
ZNF883 zinc finger protein 883

low expression

Symbol Name
MTHFSD methenyltetrahydrofolate synthetase domain containing
POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like