Lung squamous cell carcinoma_LUSC_TCGA-46-3766-01A-01R-0980-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

362 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-46-3766-01A-01R-0980-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADORA3 adenosine A3 receptor
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AMPD1 adenosine monophosphate deaminase 1
ANGPTL2 angiopoietin-like 2
ANTXR1 anthrax toxin receptor 1
ANTXR2 anthrax toxin receptor 2
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
APLNR apelin receptor
ARL14EP ADP-ribosylation factor-like 14 effector protein
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ASB7 ankyrin repeat and SOCS box containing 7
ASPN asporin
ATG4C autophagy related 4C, cysteine peptidase
ATP5L2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
ATP8B4 ATPase, class I, type 8B, member 4
BBS12 Bardet-Biedl syndrome 12
BICC1 BicC family RNA binding protein 1
BTLA B and T lymphocyte associated
C16ORF92 chromosome 16 open reading frame 92
C1ORF54 chromosome 1 open reading frame 54
C2ORF80 chromosome 2 open reading frame 80
C7ORF69 chromosome 7 open reading frame 69
CASC4 cancer susceptibility candidate 4
CCKAR cholecystokinin A receptor
CCL11 chemokine (C-C motif) ligand 11
CCL13 chemokine (C-C motif) ligand 13
CCL17 chemokine (C-C motif) ligand 17
CCL22 chemokine (C-C motif) ligand 22
CCPG1 cell cycle progression 1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CD180 CD180 molecule
CD1A CD1a molecule
CD1B CD1b molecule
CD1C CD1c molecule
CD1E CD1e molecule
CD209 CD209 molecule
CD226 CD226 molecule
CD28 CD28 molecule
CD300LD CD300 molecule-like family member d
CD59 CD59 molecule, complement regulatory protein
CDC42SE2 CDC42 small effector 2
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDK15 cyclin-dependent kinase 15
CERK ceramide kinase
CHN1 chimerin 1
CHURC1 churchill domain containing 1
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLEC10A C-type lectin domain family 10, member A
CLEC18B C-type lectin domain family 18, member B
CLEC4A C-type lectin domain family 4, member A
CLEC4C C-type lectin domain family 4, member C
CLEC4G C-type lectin domain family 4, member G
CLEC9A C-type lectin domain family 9, member A
CLIC4 chloride intracellular channel 4
CMA1 chymase 1, mast cell
CMTM6 CKLF-like MARVEL transmembrane domain containing 6
CMTR2 cap methyltransferase 2
CNRIP1 cannabinoid receptor interacting protein 1
CNTN3 contactin 3 (plasmacytoma associated)
COL10A1 collagen, type X, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL6A1 collagen, type VI, alpha 1
COL6A5 collagen, type VI, alpha 5
COPS2 COP9 signalosome subunit 2
CPA3 carboxypeptidase A3 (mast cell)
CPNE3 copine III
CPQ carboxypeptidase Q
CPVL carboxypeptidase, vitellogenic-like
CREB1 cAMP responsive element binding protein 1
CREBL2 cAMP responsive element binding protein-like 2
CRLF2 cytokine receptor-like factor 2
CSNK1G1 casein kinase 1, gamma 1
CTHRC1 collagen triple helix repeat containing 1
CTSG cathepsin G
CTSK cathepsin K
CTSO cathepsin O
CXCL12 chemokine (C-X-C motif) ligand 12
CXORF21 chromosome X open reading frame 21
CYB561D1 cytochrome b561 family, member D1
CYSLTR1 cysteinyl leukotriene receptor 1
DCP1B decapping mRNA 1B
DERL1 derlin 1
DERL3 derlin 3
DET1 de-etiolated homolog 1 (Arabidopsis)
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6
DIO2 deiodinase, iodothyronine, type II
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DPT dermatopontin
DTWD1 DTW domain containing 1
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
EDIL3 EGF-like repeats and discoidin I-like domains 3
EDNRA endothelin receptor type A
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EFR3A EFR3 homolog A (S. cerevisiae)
EID1 EP300 interacting inhibitor of differentiation 1
ELMOD2 ELMO/CED-12 domain containing 2
ELSPBP1 epididymal sperm binding protein 1
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EOMES eomesodermin
EPHX4 epoxide hydrolase 4
EVI2A ecotropic viral integration site 2A
F13A1 coagulation factor XIII, A1 polypeptide
F2R coagulation factor II (thrombin) receptor
FAM114A2 family with sequence similarity 114, member A2
FAM131B family with sequence similarity 131, member B
FAM172A family with sequence similarity 172, member A
FAM175A family with sequence similarity 175, member A
FAM198B family with sequence similarity 198, member B
FAM210B family with sequence similarity 210, member B
FAM26E family with sequence similarity 26, member E
FAM46C family with sequence similarity 46, member C
FAP fibroblast activation protein, alpha
FBLN7 fibulin 7
FBXL3 F-box and leucine-rich repeat protein 3
FBXL4 F-box and leucine-rich repeat protein 4
FBXL5 F-box and leucine-rich repeat protein 5
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FCRL5 Fc receptor-like 5
FEM1B fem-1 homolog b (C. elegans)
FGF1 fibroblast growth factor 1 (acidic)
FGF7 fibroblast growth factor 7
FGL2 fibrinogen-like 2
FILIP1L filamin A interacting protein 1-like
FKBP7 FK506 binding protein 7
FLT3 fms-related tyrosine kinase 3
FMOD fibromodulin
FOLR2 folate receptor 2 (fetal)
FOLR3 folate receptor 3 (gamma)
FPR3 formyl peptide receptor 3
FUCA1 fucosidase, alpha-L- 1, tissue
GALK2 galactokinase 2
GAPT GRB2-binding adaptor protein, transmembrane
GCSAML germinal center-associated, signaling and motility-like
GIMAP2 GTPase, IMAP family member 2
GINM1 glycoprotein integral membrane 1
GJA5 gap junction protein, alpha 5, 40kDa
GLT8D2 glycosyltransferase 8 domain containing 2
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GPC6 glypican 6
GPR21 G protein-coupled receptor 21
GPR31 G protein-coupled receptor 31
GPR34 G protein-coupled receptor 34
GPR82 G protein-coupled receptor 82
GPX8 glutathione peroxidase 8 (putative)
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
GZMK granzyme K (granzyme 3; tryptase II)
HBP1 HMG-box transcription factor 1
HCFC2 host cell factor C2
HEPH hephaestin
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HEXA hexosaminidase A (alpha polypeptide)
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HNMT histamine N-methyltransferase
HPGDS hematopoietic prostaglandin D synthase
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTRA1 HtrA serine peptidase 1
ICAM3 intercellular adhesion molecule 3
IFNAR2 interferon (alpha, beta and omega) receptor 2
IL33 interleukin 33
IL5RA interleukin 5 receptor, alpha
ILK integrin-linked kinase
IQGAP1 IQ motif containing GTPase activating protein 1
IQSEC3 IQ motif and Sec7 domain 3
ISLR immunoglobulin superfamily containing leucine-rich repeat
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITM2C integral membrane protein 2C
JCHAIN joining chain of multimeric IgA and IgM
KBTBD8 kelch repeat and BTB (POZ) domain containing 8
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KDM5A lysine (K)-specific demethylase 5A
KERA keratocan
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LAMP5 lysosomal-associated membrane protein family, member 5
LEPROT leptin receptor overlapping transcript
LINC00324 long intergenic non-protein coding RNA 324
LIPA lipase A, lysosomal acid, cholesterol esterase
LMBRD1 LMBR1 domain containing 1
LOC100192426 uncharacterized LOC100192426
LOC401463 uncharacterized LOC401463
LOC653653 adaptor-related protein complex 1, sigma 2 subunit pseudogene
LPCAT2 lysophosphatidylcholine acyltransferase 2
LXN latexin
LY86 lymphocyte antigen 86
LY96 lymphocyte antigen 96
LYSMD3 LysM, putative peptidoglycan-binding, domain containing 3
MAGEE2 melanoma antigen family E2
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP2K5 mitogen-activated protein kinase kinase 5
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MCF2 MCF.2 cell line derived transforming sequence
MEF2C myocyte enhancer factor 2C
METTL11B methyltransferase like 11B
MFAP3 microfibrillar-associated protein 3
MFGE8 milk fat globule-EGF factor 8 protein
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type
MMD monocyte to macrophage differentiation-associated
MMGT1 membrane magnesium transporter 1
MPEG1 macrophage expressed 1
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MSL3 male-specific lethal 3 homolog (Drosophila)
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYLK myosin light chain kinase
NAAA N-acylethanolamine acid amidase
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1
NCOA4 nuclear receptor coactivator 4
NDP Norrie disease (pseudoglioma)
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1
NID2 nidogen 2 (osteonidogen)
NOX4 NADPH oxidase 4
NPTN neuroplastin
NT5C1A 5'-nucleotidase, cytosolic IA
NUAK1 NUAK family, SNF1-like kinase, 1
OAZ2 ornithine decarboxylase antizyme 2
OLFML1 olfactomedin-like 1
OLFML2B olfactomedin-like 2B
OMD osteomodulin
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OSBPL8 oxysterol binding protein-like 8
OSTM1 osteopetrosis associated transmembrane protein 1
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAMR1 peptidase domain containing associated with muscle regeneration 1
PAPD4 PAP associated domain containing 4
PARVA parvin, alpha
PCDHGB4 protocadherin gamma subfamily B, 4
PDE1A phosphodiesterase 1A, calmodulin-dependent
PDGFRL platelet-derived growth factor receptor-like
PDLIM3 PDZ and LIM domain 3
PI15 peptidase inhibitor 15
PIAS1 protein inhibitor of activated STAT, 1
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PKM pyruvate kinase, muscle
PLD4 phospholipase D family, member 4
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLXNC1 plexin C1
PMCH pro-melanin-concentrating hormone
POSTN periostin, osteoblast specific factor
PPAPDC1A phosphatidic acid phosphatase type 2 domain containing 1A
PPAPDC3 phosphatidic acid phosphatase type 2 domain containing 3
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPY pancreatic polypeptide
PQLC3 PQ loop repeat containing 3
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKG1 protein kinase, cGMP-dependent, type I
PRSS23 protease, serine, 23
PTEN phosphatase and tensin homolog
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional)
RAB11A RAB11A, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RAP1A RAP1A, member of RAS oncogene family
RBM7 RNA binding motif protein 7
RCAN2 regulator of calcineurin 2
REEP3 receptor accessory protein 3
RFTN2 raftlin family member 2
RGS18 regulator of G-protein signaling 18
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNASE3 ribonuclease, RNase A family, 3
RNASE6 ribonuclease, RNase A family, k6
RNF139 ring finger protein 139
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RSBN1 round spermatid basic protein 1
RTN2 reticulon 2
S100B S100 calcium binding protein B
SAMD3 sterile alpha motif domain containing 3
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SENP8 SUMO/sentrin specific peptidase family member 8
SETD7 SET domain containing (lysine methyltransferase) 7
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SH2D1A SH2 domain containing 1A
SH3BGRL SH3 domain binding glutamate-rich protein like
SHC4 SHC (Src homology 2 domain containing) family, member 4
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SPACA5 sperm acrosome associated 5
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae)
SPPL2A signal peptide peptidase like 2A
SPRED1 sprouty-related, EVH1 domain containing 1
SSPN sarcospan
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STK17B serine/threonine kinase 17b
SULF1 sulfatase 1
SUMF1 sulfatase modifying factor 1
TAGLN transgelin
TAS2R40 taste receptor, type 2, member 40
TCEANC transcription elongation factor A (SII) N-terminal and central domain containing
TDO2 tryptophan 2,3-dioxygenase
TGFB3 transforming growth factor, beta 3
THY1 Thy-1 cell surface antigen
TICAM2 toll-like receptor adaptor molecule 2
TIMP1 TIMP metallopeptidase inhibitor 1
TLR7 toll-like receptor 7
TMCO2 transmembrane and coiled-coil domains 2
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMEM169 transmembrane protein 169
TMEM176B transmembrane protein 176B
TMEM184C transmembrane protein 184C
TMEM200A transmembrane protein 200A
TMEM236 transmembrane protein 236
TMEM50A transmembrane protein 50A
TMEM59 transmembrane protein 59
TMEM9B TMEM9 domain family, member B
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TP53INP1 tumor protein p53 inducible nuclear protein 1
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
TRAM1 translocation associated membrane protein 1
TRIM61 tripartite motif containing 61
TRIP4 thyroid hormone receptor interactor 4
TSPAN2 tetraspanin 2
TTC38 tetratricopeptide repeat domain 38
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
UBE2J1 ubiquitin-conjugating enzyme E2, J1
USP8 ubiquitin specific peptidase 8
UTS2 urotensin 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WBP1L WW domain binding protein 1-like
WNT2 wingless-type MMTV integration site family member 2
XBP1 X-box binding protein 1
XCR1 chemokine (C motif) receptor 1
YIPF5 Yip1 domain family, member 5
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZBTB6 zinc finger and BTB domain containing 6
ZCCHC24 zinc finger, CCHC domain containing 24
ZCCHC5 zinc finger, CCHC domain containing 5
ZCWPW2 zinc finger, CW type with PWWP domain 2
ZNF441 zinc finger protein 441
ZNF501 zinc finger protein 501
ZNF699 zinc finger protein 699
ZNF702P zinc finger protein 702, pseudogene

low expression

Symbol Name
NXF1 nuclear RNA export factor 1
SFSWAP splicing factor, suppressor of white-apricot family