Lung squamous cell carcinoma_LUSC_TCGA-43-6773-01A-41R-1949-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

307 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-43-6773-01A-41R-1949-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ABLIM1 actin binding LIM protein 1
ADAM6 ADAM metallopeptidase domain 6 (pseudogene)
ADGRG5 adhesion G protein-coupled receptor G5
AEBP1 AE binding protein 1
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
ANKRD55 ankyrin repeat domain 55
ANXA6 annexin A6
ARMC12 armadillo repeat containing 12
ATP13A1 ATPase type 13A1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATRN attractin
AVEN apoptosis, caspase activation inhibitor
BCO2 beta-carotene oxygenase 2
BGN biglycan
BHLHA15 basic helix-loop-helix family, member a15
BHLHE22 basic helix-loop-helix family, member e22
BLK BLK proto-oncogene, Src family tyrosine kinase
BMP7 bone morphogenetic protein 7
BTLA B and T lymphocyte associated
C10ORF54 chromosome 10 open reading frame 54
C15ORF59 chromosome 15 open reading frame 59
C19ORF35 chromosome 19 open reading frame 35
C20ORF27 chromosome 20 open reading frame 27
C4ORF45 chromosome 4 open reading frame 45
C4ORF50 chromosome 4 open reading frame 50
C7ORF61 chromosome 7 open reading frame 61
C9ORF114 chromosome 9 open reading frame 114
CD180 CD180 molecule
CD27 CD27 molecule
CD38 CD38 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD79A CD79a molecule, immunoglobulin-associated alpha
CDHR1 cadherin-related family member 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2A-AS1 CDKN2A antisense RNA 1 (head to head)
CECR1 cat eye syndrome chromosome region, candidate 1
CHRDL2 chordin-like 2
CLDND2 claudin domain containing 2
CLU clusterin
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
CMTR1 cap methyltransferase 1
CNOT4 CCR4-NOT transcription complex, subunit 4
COL15A1 collagen, type XV, alpha 1
COMP cartilage oligomeric matrix protein
CPLX2 complexin 2
CPNE5 copine V
CREB3L2 cAMP responsive element binding protein 3-like 2
CRIP1 cysteine-rich protein 1 (intestinal)
CST7 cystatin F (leukocystatin)
CTNS cystinosin, lysosomal cystine transporter
CXCR4 chemokine (C-X-C motif) receptor 4
CYBA cytochrome b-245, alpha polypeptide
CYR61 cysteine-rich, angiogenic inducer, 61
CYTIP cytohesin 1 interacting protein
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DERL3 derlin 3
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DPEP1 dipeptidase 1 (renal)
DPP7 dipeptidyl-peptidase 7
DPT dermatopontin
DUSP5 dual specificity phosphatase 5
ELL2 elongation factor, RNA polymerase II, 2
EMILIN1 elastin microfibril interfacer 1
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
ETFB electron-transfer-flavoprotein, beta polypeptide
EXOC4 exocyst complex component 4
FAM102A family with sequence similarity 102, member A
FAM110C family with sequence similarity 110, member C
FAM159A family with sequence similarity 159, member A
FAM167B family with sequence similarity 167, member B
FAM46C family with sequence similarity 46, member C
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCMR Fc fragment of IgM receptor
FCRL5 Fc receptor-like 5
FCRLA Fc receptor-like A
FERMT1 fermitin family member 1
FICD FIC domain containing
FKBP11 FK506 binding protein 11, 19 kDa
FKBP2 FK506 binding protein 2, 13kDa
FKBP5 FK506 binding protein 5
FMOD fibromodulin
FOXS1 forkhead box S1
GAL3ST4 galactose-3-O-sulfotransferase 4
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13
GAS1 growth arrest-specific 1
GATS GATS, stromal antigen 3 opposite strand
GATSL2 GATS protein-like 2
GDF3 growth differentiation factor 3
GGT5 gamma-glutamyltransferase 5
GH1 growth hormone 1
GLI1 GLI family zinc finger 1
GPC5 glypican 5
GPR149 G protein-coupled receptor 149
GPR150 G protein-coupled receptor 150
GPR161 G protein-coupled receptor 161
GREM1 gremlin 1, DAN family BMP antagonist
GRM1 glutamate receptor, metabotropic 1
GSG1L GSG1-like
GSN gelsolin
GSTM3 glutathione S-transferase mu 3 (brain)
GSTM4 glutathione S-transferase mu 4
GTF2A1L general transcription factor IIA, 1-like
GZMK granzyme K (granzyme 3; tryptase II)
HCK HCK proto-oncogene, Src family tyrosine kinase
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HKDC1 hexokinase domain containing 1
HLA-DOB major histocompatibility complex, class II, DO beta
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1
HOXA7 homeobox A7
HSH2D hematopoietic SH2 domain containing
HTRA3 HtrA serine peptidase 3
ICAM2 intercellular adhesion molecule 2
ICAM3 intercellular adhesion molecule 3
IFI35 interferon-induced protein 35
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
IFNA17 interferon, alpha 17
IGFLR1 IGF-like family receptor 1
IGLL1 immunoglobulin lambda-like polypeptide 1
IL5RA interleukin 5 receptor, alpha
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INGX inhibitor of growth family, X-linked, pseudogene
IRF7 interferon regulatory factor 7
ISG15 ISG15 ubiquitin-like modifier
ISG20 interferon stimulated exonuclease gene 20kDa
ITGB7 integrin, beta 7
ITM2C integral membrane protein 2C
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPRIPL1 inositol 1,4,5-trisphosphate receptor interacting protein-like 1
JSRP1 junctional sarcoplasmic reticulum protein 1
KANK1 KN motif and ankyrin repeat domains 1
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KIAA0319 KIAA0319
KIAA1755 KIAA1755
KIF16B kinesin family member 16B
KLF2 Kruppel-like factor 2
KLK5 kallikrein-related peptidase 5
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LALBA lactalbumin, alpha-
LAX1 lymphocyte transmembrane adaptor 1
LHX5 LIM homeobox 5
LIME1 Lck interacting transmembrane adaptor 1
LMBR1 limb development membrane protein 1
LMF1 lipase maturation factor 1
LMX1A LIM homeobox transcription factor 1, alpha
LOC100129534 small nuclear ribonucleoprotein polypeptide N pseudogene
LOC285696 uncharacterized LOC285696
LRIT2 leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
LY9 lymphocyte antigen 9
MAP1A microtubule-associated protein 1A
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MATN2 matrilin 2
MBOAT2 membrane bound O-acyltransferase domain containing 2
MEF2B myocyte enhancer factor 2B
MEI1 meiosis inhibitor 1
METTL24 methyltransferase like 24
MFF mitochondrial fission factor
MLKL mixed lineage kinase domain-like
MRAP melanocortin 2 receptor accessory protein
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
MXRA8 matrix-remodelling associated 8
MYH14 myosin, heavy chain 14, non-muscle
MZT2B mitotic spindle organizing protein 2B
NEFL neurofilament, light polypeptide
NOP56 NOP56 ribonucleoprotein
NPW neuropeptide W
NPY4R neuropeptide Y receptor Y4
NR2E1 nuclear receptor subfamily 2, group E, member 1
NUGGC nuclear GTPase, germinal center associated
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OASL 2'-5'-oligoadenylate synthetase-like
OLFML2B olfactomedin-like 2B
OPRK1 opioid receptor, kappa 1
OPRL1 opiate receptor-like 1
OR2B11 olfactory receptor, family 2, subfamily B, member 11
OR2D2 olfactory receptor, family 2, subfamily D, member 2
OR56B1 olfactory receptor, family 56, subfamily B, member 1
OTOP3 otopetrin 3
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P2RY8 purinergic receptor P2Y, G-protein coupled, 8
P4HA3 prolyl 4-hydroxylase, alpha polypeptide III
PARP10 poly (ADP-ribose) polymerase family, member 10
PHF19 PHD finger protein 19
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G2D phospholipase A2, group IID
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
PODN podocan
POU2AF1 POU class 2 associating factor 1
POU2F2 POU class 2 homeobox 2
PRDM1 PR domain containing 1, with ZNF domain
PRELP proline/arginine-rich end leucine-rich repeat protein
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTCHD1 patched domain containing 1
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAP1GAP RAP1 GTPase activating protein
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RCSD1 RCSD domain containing 1
RFPL1S RFPL1 antisense RNA 1
RGS1 regulator of G-protein signaling 1
RGS19 regulator of G-protein signaling 19
RHOH ras homolog family member H
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RSAD2 radical S-adenosyl methionine domain containing 2
SCARA3 scavenger receptor class A, member 3
SCML4 sex comb on midleg-like 4 (Drosophila)
SCN9A sodium channel, voltage gated, type IX alpha subunit
SELPLG selectin P ligand
SEPT5 septin 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP4 secreted frizzled-related protein 4
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIL1 SIL1 nucleotide exchange factor
SLA Src-like-adaptor
SLAMF1 signaling lymphocytic activation molecule family member 1
SLAMF6 SLAM family member 6
SLAMF7 SLAM family member 7
SLC22A17 solute carrier family 22, member 17
SLC25A41 solute carrier family 25, member 41
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SMAP2 small ArfGAP2
SMOC2 SPARC related modular calcium binding 2
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNAI3 snail family zinc finger 3
SNORA80A small nucleolar RNA, H/ACA box 80A
SOST sclerostin
SP110 SP110 nuclear body protein
SP140 SP140 nuclear body protein
SPAG4 sperm associated antigen 4
SPATS2 spermatogenesis associated, serine-rich 2
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SSC5D scavenger receptor cysteine rich family, 5 domains
SSR4 signal sequence receptor, delta
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STMN3 stathmin-like 3
STXBP5L syntaxin binding protein 5-like
SYK spleen tyrosine kinase
SYNDIG1 synapse differentiation inducing 1
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAGAP T-cell activation RhoGTPase activating protein
TARM1 T cell-interacting, activating receptor on myeloid cells 1
TAS1R3 taste receptor, type 1, member 3
TBCEL tubulin folding cofactor E-like
TDP2 tyrosyl-DNA phosphodiesterase 2
THY1 Thy-1 cell surface antigen
TIAM2 T-cell lymphoma invasion and metastasis 2
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TLR9 toll-like receptor 9
TMEM140 transmembrane protein 140
TMEM176A transmembrane protein 176A
TMEM176B transmembrane protein 176B
TMUB1 transmembrane and ubiquitin-like domain containing 1
TNFAIP8L3 tumor necrosis factor, alpha-induced protein 8-like 3
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TPM2 tropomyosin 2 (beta)
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TREX1 three prime repair exonuclease 1
TRIM14 tripartite motif containing 14
TSC22D3 TSC22 domain family, member 3
TSPAN7 tetraspanin 7
TXNDC11 thioredoxin domain containing 11
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
TXNRD1 thioredoxin reductase 1
TYRO3 TYRO3 protein tyrosine kinase
UBE2H ubiquitin-conjugating enzyme E2H
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
USP18 ubiquitin specific peptidase 18
USP50 ubiquitin specific peptidase 50
VHLL von Hippel-Lindau tumor suppressor-like
VSIG10L V-set and immunoglobulin domain containing 10 like
VWA7 von Willebrand factor A domain containing 7
WAS Wiskott-Aldrich syndrome
XAF1 XIAP associated factor 1
XBP1 X-box binding protein 1
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
ZBP1 Z-DNA binding protein 1
ZBTB32 zinc finger and BTB domain containing 32
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZC3HC1 zinc finger, C3HC-type containing 1
ZDHHC18 zinc finger, DHHC-type containing 18
ZFPM2 zinc finger protein, FOG family member 2
ZNF425 zinc finger protein 425

low expression

Symbol Name
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1