Lung squamous cell carcinoma_LUSC_TCGA-43-6770-01A-11R-1820-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

399 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-43-6770-01A-11R-1820-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AARS alanyl-tRNA synthetase
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ACO2 aconitase 2, mitochondrial
AGO3 argonaute RISC catalytic component 3
AKR7A2P1 aldo-keto reductase family 7, member A2 pseudogene 1
ALKBH5 AlkB family member 5, RNA demethylase
AMOTL1 angiomotin like 1
AMPD2 adenosine monophosphate deaminase 2
ANAPC1 anaphase promoting complex subunit 1
ANKRD50 ankyrin repeat domain 50
AOAH acyloxyacyl hydrolase (neutrophil)
AP1B1 adaptor-related protein complex 1, beta 1 subunit
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOOL apolipoprotein O-like
ARL10 ADP-ribosylation factor-like 10
ARL4C ADP-ribosylation factor-like 4C
ARMC5 armadillo repeat containing 5
ARTN artemin
ASB1 ankyrin repeat and SOCS box containing 1
ASIC5 acid sensing (proton gated) ion channel family member 5
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BEND4 BEN domain containing 4
BEND5 BEN domain containing 5
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BICD2 bicaudal D homolog 2 (Drosophila)
C11ORF65 chromosome 11 open reading frame 65
C17ORF107 chromosome 17 open reading frame 107
C22ORF23 chromosome 22 open reading frame 23
C22ORF24 chromosome 22 open reading frame 24
C22ORF31 chromosome 22 open reading frame 31
C22ORF46 chromosome 22 open reading frame 46
C4ORF29 chromosome 4 open reading frame 29
C4ORF3 chromosome 4 open reading frame 3
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CBX6 chromobox homolog 6
CCDC134 coiled-coil domain containing 134
CCND2 cyclin D2
CD163L1 CD163 molecule-like 1
CDRT1 CMT1A duplicated region transcript 1
CDRT15P1 CMT1A duplicated region transcript 15 pseudogene 1
CEP290 centrosomal protein 290kDa
CERK ceramide kinase
CHD3 chromodomain helicase DNA binding protein 3
CHID1 chitinase domain containing 1
CHM choroideremia (Rab escort protein 1)
CHRM3 cholinergic receptor, muscarinic 3
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLASP1 cytoplasmic linker associated protein 1
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COL24A1 collagen, type XXIV, alpha 1
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CREG2 cellular repressor of E1A-stimulated genes 2
CRYGS crystallin, gamma S
CSRP2 cysteine and glycine-rich protein 2
CUL4B cullin 4B
CXORF40A chromosome X open reading frame 40A
CXORF40B chromosome X open reading frame 40B
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP4F30P cytochrome P450, family 4, subfamily F, polypeptide 30, pseudogene
DAOA D-amino acid oxidase activator
DAP death-associated protein
DCAF12L1 DDB1 and CUL4 associated factor 12-like 1
DCAF12L2 DDB1 and CUL4 associated factor 12-like 2
DEAF1 DEAF1 transcription factor
DEGS1 delta(4)-desaturase, sphingolipid 1
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DIAPH2 diaphanous-related formin 2
DIRC3 disrupted in renal carcinoma 3
DKC1 dyskeratosis congenita 1, dyskerin
DMC1 DNA meiotic recombinase 1
DMRT2 doublesex and mab-3 related transcription factor 2
DNAH10 dynein, axonemal, heavy chain 10
DNAJB3 DnaJ (Hsp40) homolog, subfamily B, member 3
DNAJB7 DnaJ (Hsp40) homolog, subfamily B, member 7
DOK6 docking protein 6
DRG2 developmentally regulated GTP binding protein 2
DSEL dermatan sulfate epimerase-like
EFNB2 ephrin-B2
EIF3D eukaryotic translation initiation factor 3, subunit D
EMD emerin
EME1 essential meiotic structure-specific endonuclease 1
EML1 echinoderm microtubule associated protein like 1
EP300 E1A binding protein p300
EPN2 epsin 2
ESYT2 extended synaptotagmin-like protein 2
ETV1 ets variant 1
FAM167A-AS1 FAM167A antisense RNA 1
FAM196B family with sequence similarity 196, member B
FAM3A family with sequence similarity 3, member A
FAM83G family with sequence similarity 83, member G
FAXC failed axon connections homolog (Drosophila)
FBXL21 F-box and leucine-rich repeat protein 21 (gene/pseudogene)
FEZF1 FEZ family zinc finger 1
FGD6 FYVE, RhoGEF and PH domain containing 6
FGF12 fibroblast growth factor 12
FLII flightless I homolog (Drosophila)
FLJ33360 FLJ33360 protein
FLNA filamin A, alpha
FOXB2 forkhead box B2
FRAS1 Fraser extracellular matrix complex subunit 1
FREM2 FRAS1 related extracellular matrix protein 2
FRRS1 ferric-chelate reductase 1
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
GAB1 GRB2-associated binding protein 1
GCAT glycine C-acetyltransferase
GCSH glycine cleavage system protein H (aminomethyl carrier)
GDI1 GDP dissociation inhibitor 1
GEMIN4 gem (nuclear organelle) associated protein 4
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GLIPR1L1 GLI pathogenesis-related 1 like 1
GPC3 glypican 3
GPRC5D G protein-coupled receptor, class C, group 5, member D
GRM1 glutamate receptor, metabotropic 1
GRM6 glutamate receptor, metabotropic 6
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene)
GTSE1 G-2 and S-phase expressed 1
HDAC4 histone deacetylase 4
HECA headcase homolog (Drosophila)
HK1 hexokinase 1
HPS4 Hermansky-Pudlak syndrome 4
HRAS Harvey rat sarcoma viral oncogene homolog
HRASLS HRAS-like suppressor
HSPA4L heat shock 70kDa protein 4-like
HSPA8 heat shock 70kDa protein 8
HTN3 histatin 3
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL31RA interleukin 31 receptor A
INTS4P2 integrator complex subunit 4 pseudogene 2
IPO13 importin 13
IRAK1 interleukin-1 receptor-associated kinase 1
IRX6 iroquois homeobox 6
JMJD8 jumonji domain containing 8
JOSD1 Josephin domain containing 1
JPH1 junctophilin 1
JPX JPX transcript, XIST activator (non-protein coding)
KAT6B K(lysine) acetyltransferase 6B
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
KIAA0100 KIAA0100
KIAA0922 KIAA0922
KIF13A kinesin family member 13A
KIF4A kinesin family member 4A
KIF4B kinesin family member 4B
KLHL29 kelch-like family member 29
KLHL4 kelch-like family member 4
KLHL5 kelch-like family member 5
KRBA1 KRAB-A domain containing 1
KREMEN1 kringle containing transmembrane protein 1
KRT5 keratin 5, type II
KRTAP9-8 keratin associated protein 9-8
LARP1B La ribonucleoprotein domain family, member 1B
LDOC1L leucine zipper, down-regulated in cancer 1-like
LINC00161 long intergenic non-protein coding RNA 161
LINC01465 long intergenic non-protein coding RNA 1465
LOC100130691 uncharacterized LOC100130691
LOC100134368 uncharacterized LOC100134368
LOC143666 uncharacterized LOC143666
LOC284009 uncharacterized LOC284009
LOC401127 WD repeat domain 5 pseudogene
LONP1 lon peptidase 1, mitochondrial
LRRIQ3 leucine-rich repeats and IQ motif containing 3
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAGEC1 melanoma antigen family C1
MAMLD1 mastermind-like domain containing 1
MAP1A microtubule-associated protein 1A
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK7 mitogen-activated protein kinase 7
MB21D2 Mab-21 domain containing 2
MBD1 methyl-CpG binding domain protein 1
MBNL3 muscleblind-like splicing regulator 3
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
MCM3AP minichromosome maintenance complex component 3 associated protein
MCM3AP-AS1 MCM3AP antisense RNA 1
MCM5 minichromosome maintenance complex component 5
MED12 mediator complex subunit 12
METAP2 methionyl aminopeptidase 2
METTL16 methyltransferase like 16
MIEF1 mitochondrial elongation factor 1
MKNK1 MAP kinase interacting serine/threonine kinase 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MPPED1 metallophosphoesterase domain containing 1
MRAP2 melanocortin 2 receptor accessory protein 2
MRPL23 mitochondrial ribosomal protein L23
MRPL42 mitochondrial ribosomal protein L42
MTCP1 mature T-cell proliferation 1
MTMR1 myotubularin related protein 1
MTO1 mitochondrial tRNA translation optimization 1
MYBBP1A MYB binding protein (P160) 1a
MYO5A myosin VA (heavy chain 12, myoxin)
N4BP2 NEDD4 binding protein 2
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit
NAGA N-acetylgalactosaminidase, alpha-
NAP1L2 nucleosome assembly protein 1-like 2
NCAPG2 non-SMC condensin II complex, subunit G2
NDRG1 N-myc downstream regulated 1
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
NEFL neurofilament, light polypeptide
NF2 neurofibromin 2 (merlin)
NHSL1 NHS-like 1
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NLN neurolysin (metallopeptidase M3 family)
NONO non-POU domain containing, octamer-binding
NPBWR1 neuropeptides B/W receptor 1
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NRD1 nardilysin (N-arginine dibasic convertase)
NRXN1 neurexin 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUP88 nucleoporin 88kDa
ODC1 ornithine decarboxylase 1
OR10A3 olfactory receptor, family 10, subfamily A, member 3
OR51T1 olfactory receptor, family 51, subfamily T, member 1
OR56B4 olfactory receptor, family 56, subfamily B, member 4
OR6C65 olfactory receptor, family 6, subfamily C, member 65
OR6T1 olfactory receptor, family 6, subfamily T, member 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P3H1 prolyl 3-hydroxylase 1
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PANX2 pannexin 2
PCDH18 protocadherin 18
PCDH19 protocadherin 19
PCSK5 proprotein convertase subtilisin/kexin type 5
PCSK9 proprotein convertase subtilisin/kexin type 9
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase
PES1 pescadillo ribosomal biogenesis factor 1
PGRMC2 progesterone receptor membrane component 2
PHRF1 PHD and ring finger domains 1
PHTF1 putative homeodomain transcription factor 1
PITPNM3 PITPNM family member 3
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKP1 plakophilin 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAC8 placenta-specific 8
PLD6 phospholipase D family, member 6
PLK4 polo-like kinase 4
PNMAL2 paraneoplastic Ma antigen family-like 2
PNPLA5 patatin-like phospholipase domain containing 5
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
POLG polymerase (DNA directed), gamma
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
PRKX protein kinase, X-linked
PRPF8 pre-mRNA processing factor 8
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2
PRR11 proline rich 11
PRR14L proline rich 14-like
PRR3 proline rich 3
PRR34 proline rich 34
PRRC2B proline-rich coiled-coil 2B
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
PYY peptide YY
RANBP2 RAN binding protein 2
RANGAP1 Ran GTPase activating protein 1
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
REPS1 RALBP1 associated Eps domain containing 1
RFPL3 ret finger protein-like 3
RFPL3S RFPL3 antisense
RFX8 RFX family member 8, lacking RFX DNA binding domain
RGMA repulsive guidance molecule family member a
RHBDD3 rhomboid domain containing 3
RIC8A RIC8 guanine nucleotide exchange factor A
RIMBP3C RIMS binding protein 3C
RLIM ring finger protein, LIM domain interacting
RNF112 ring finger protein 112
RNF113A ring finger protein 113A
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF215 ring finger protein 215
RNF217-AS1 RNF217 antisense RNA 1 (head to head)
RPAP1 RNA polymerase II associated protein 1
RPL3 ribosomal protein L3
RPS10P7 ribosomal protein S10 pseudogene 7
RPS4X ribosomal protein S4, X-linked
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RRM1 ribonucleotide reductase M1
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase
SAMM50 SAMM50 sorting and assembly machinery component
SCLT1 sodium channel and clathrin linker 1
SEC24C SEC24 family member C
SEC24D SEC24 family member D
SEC31A SEC31 homolog A (S. cerevisiae)
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
SESN3 sestrin 3
SF3A1 splicing factor 3a, subunit 1, 120kDa
SIPA1L2 signal-induced proliferation-associated 1 like 2
SLC10A3 solute carrier family 10, member 3
SLC16A13 solute carrier family 16, member 13
SLC16A14 solute carrier family 16, member 14
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC35G6 solute carrier family 35, member G6
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SLITRK4 SLIT and NTRK-like family, member 4
SLX4 SLX4 structure-specific endonuclease subunit
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8
SMG6 SMG6 nonsense mediated mRNA decay factor
SNORA25 small nucleolar RNA, H/ACA box 25
SNORA71B small nucleolar RNA, H/ACA box 71B
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNX12 sorting nexin 12
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX5 SRY (sex determining region Y)-box 5
SOX6 SRY (sex determining region Y)-box 6
SPATA5 spermatogenesis associated 5
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SREBF2 sterol regulatory element binding transcription factor 2
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
STAG2 stromal antigen 2
STK40 serine/threonine kinase 40
TAS2R31 taste receptor, type 2, member 31
TAS2R43 taste receptor, type 2, member 43
TBC1D22A TBC1 domain family, member 22A
TBL1X transducin (beta)-like 1X-linked
TEDDM1 transmembrane epididymal protein 1
TET1 tet methylcytosine dioxygenase 1
THEMIS thymocyte selection associated
THOC3 THO complex 3
THOC5 THO complex 5
THSD7B thrombospondin, type I, domain containing 7B
TIGD7 tigger transposable element derived 7
TMEM184B transmembrane protein 184B
TMEM185A transmembrane protein 185A
TMEM39B transmembrane protein 39B
TMLHE trimethyllysine hydroxylase, epsilon
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TNC tenascin C
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNK2 tyrosine kinase, non-receptor, 2
TNRC6B trinucleotide repeat containing 6B
TOP3A topoisomerase (DNA) III alpha
TP53 tumor protein p53
TRIM16 tripartite motif containing 16
TRIM16L tripartite motif containing 16-like
TRIM2 tripartite motif containing 2
TRIM25 tripartite motif containing 25
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TSNAX-DISC1 TSNAX-DISC1 readthrough (NMD candidate)
TSPAN18 tetraspanin 18
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TSSC4 tumor suppressing subtransferable candidate 4
TTC12 tetratricopeptide repeat domain 12
TTC3 tetratricopeptide repeat domain 3
TTLL12 tubulin tyrosine ligase-like family member 12
TUBGCP6 tubulin, gamma complex associated protein 6
TUFT1 tuftelin 1
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
UBL4A ubiquitin-like 4A
UBN1 ubinuclein 1
UGDH UDP-glucose 6-dehydrogenase
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
USP22 ubiquitin specific peptidase 22
USP28 ubiquitin specific peptidase 28
VEZT vezatin, adherens junctions transmembrane protein
WASF2 WAS protein family, member 2
WDR24 WD repeat domain 24
WDR4 WD repeat domain 4
WDR47 WD repeat domain 47
WNK2 WNK lysine deficient protein kinase 2
XIST X inactive specific transcript (non-protein coding)
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YBEY ybeY metallopeptidase (putative)
ZBED4 zinc finger, BED-type containing 4
ZC3H7B zinc finger CCCH-type containing 7B
ZNF154 zinc finger protein 154
ZNF200 zinc finger protein 200
ZNF229 zinc finger protein 229
ZNF275 zinc finger protein 275
ZNF286B zinc finger protein 286B
ZNF454 zinc finger protein 454
ZNF492 zinc finger protein 492
ZNF503-AS2 ZNF503 antisense RNA 2
ZNF559 zinc finger protein 559
ZNF589 zinc finger protein 589
ZNF597 zinc finger protein 597
ZNF625 zinc finger protein 625
ZNF669 zinc finger protein 669
ZNF70 zinc finger protein 70
ZNF732 zinc finger protein 732
ZNF827 zinc finger protein 827

low expression

Symbol Name
BMPR1A bone morphogenetic protein receptor, type IA
VRK3 vaccinia related kinase 3