Lung squamous cell carcinoma_LUSC_TCGA-39-5039-01A-01R-1443-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

328 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-39-5039-01A-01R-1443-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACSM3 acyl-CoA synthetase medium-chain family member 3
ACSS2 acyl-CoA synthetase short-chain family member 2
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTG1 actin gamma 1
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16
AGA aspartylglucosaminidase
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGR2 anterior gradient 2
AGTR2 angiotensin II receptor, type 2
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase
ALPL alkaline phosphatase, liver/bone/kidney
AMACR alpha-methylacyl-CoA racemase
AMY1A amylase, alpha 1A (salivary)
AMY2A amylase, alpha 2A (pancreatic)
ANTXR2 anthrax toxin receptor 2
ANXA5 annexin A5
ANXA8 annexin A8
APEH acylaminoacyl-peptide hydrolase
APRT adenine phosphoribosyltransferase
ARF6 ADP-ribosylation factor 6
ARFIP1 ADP-ribosylation factor interacting protein 1
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ATP10D ATPase, class V, type 10D
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
BCL10 B-cell CLL/lymphoma 10
BFAR bifunctional apoptosis regulator
C12ORF54 chromosome 12 open reading frame 54
C14ORF166 chromosome 14 open reading frame 166
C14ORF28 chromosome 14 open reading frame 28
C16ORF45 chromosome 16 open reading frame 45
C16ORF58 chromosome 16 open reading frame 58
C4BPA complement component 4 binding protein, alpha
C5 complement component 5
C7 complement component 7
C8ORF48 chromosome 8 open reading frame 48
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CBY1 chibby homolog 1 (Drosophila)
CCNI cyclin I
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDH8 cadherin 8, type 2
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CES2 carboxylesterase 2
CFAP221 cilia and flagella associated protein 221
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIA chitinase, acidic
CHKB choline kinase beta
CHP2 calcineurin-like EF-hand protein 2
CHRDL2 chordin-like 2
CIB1 calcium and integrin binding 1 (calmyrin)
CISH cytokine inducible SH2-containing protein
CLCA4 chloride channel accessory 4
CLCN1 chloride channel, voltage-sensitive 1
CLDN2 claudin 2
CLGN calmegin
CNGA1 cyclic nucleotide gated channel alpha 1
CNN2 calponin 2
COPE coatomer protein complex, subunit epsilon
COX7B2 cytochrome c oxidase subunit VIIb2
CPZ carboxypeptidase Z
CREB3L1 cAMP responsive element binding protein 3-like 1
CRELD2 cysteine-rich with EGF-like domains 2
CRTAC1 cartilage acidic protein 1
CRYGN crystallin, gamma N
CSAG1 chondrosarcoma associated gene 1
CSAG3 CSAG family, member 3
CST13P cystatin 13, pseudogene
CST2 cystatin SA
CST3 cystatin C
CTSE cathepsin E
CTSH cathepsin H
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe)
CXORF66 chromosome X open reading frame 66
CYBA cytochrome b-245, alpha polypeptide
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DAD1 defender against cell death 1
DENND6B DENN/MADD domain containing 6B
DESI1 desumoylating isopeptidase 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DHRS9 dehydrogenase/reductase (SDR family) member 9
DMBT1 deleted in malignant brain tumors 1
DNAAF2 dynein, axonemal, assembly factor 2
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNASE1L1 deoxyribonuclease I-like 1
DUSP23 dual specificity phosphatase 23
EDNRA endothelin receptor type A
EHD2 EH-domain containing 2
EIF3F eukaryotic translation initiation factor 3, subunit F
ELMOD2 ELMO/CED-12 domain containing 2
ELOVL1 ELOVL fatty acid elongase 1
ERCC1 excision repair cross-complementation group 1
ERO1L ERO1-like (S. cerevisiae)
ETFDH electron-transferring-flavoprotein dehydrogenase
ETHE1 ethylmalonic encephalopathy 1
EXOSC7 exosome component 7
F3 coagulation factor III (thromboplastin, tissue factor)
FAM118B family with sequence similarity 118, member B
FAM179B family with sequence similarity 179, member B
FAM3D family with sequence similarity 3, member D
FAM71E1 family with sequence similarity 71, member E1
FAM83A family with sequence similarity 83, member A
FANCM Fanconi anemia, complementation group M
FBXO39 F-box protein 39
FER1L6 fer-1-like family member 6
FGF7 fibroblast growth factor 7
FGG fibrinogen gamma chain
FKBP3 FK506 binding protein 3, 25kDa
FPGS folylpolyglutamate synthase
FRMD6 FERM domain containing 6
FXYD5 FXYD domain containing ion transport regulator 5
GALE UDP-galactose-4-epimerase
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GDE1 glycerophosphodiester phosphodiesterase 1
GGT1 gamma-glutamyltransferase 1
GGT5 gamma-glutamyltransferase 5
GJB4 gap junction protein, beta 4, 30.3kDa
GJB5 gap junction protein, beta 5, 31.1kDa
GLTSCR2 glioma tumor suppressor candidate region gene 2
GMPPA GDP-mannose pyrophosphorylase A
GMPPB GDP-mannose pyrophosphorylase B
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GPR89B G protein-coupled receptor 89B
GPRC5C G protein-coupled receptor, class C, group 5, member C
GPX4 glutathione peroxidase 4
GSTT1 glutathione S-transferase theta 1
HABP2 hyaluronan binding protein 2
HBE1 hemoglobin, epsilon 1
HCG9 HLA complex group 9 (non-protein coding)
HHIP hedgehog interacting protein
HM13 histocompatibility (minor) 13
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HP haptoglobin
HPR haptoglobin-related protein
HPSE heparanase
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HYI hydroxypyruvate isomerase (putative)
IFITM2 interferon induced transmembrane protein 2
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP4 insulin-like growth factor binding protein 4
IGFBP7 insulin-like growth factor binding protein 7
IGSF22 immunoglobulin superfamily, member 22
IL1RN interleukin 1 receptor antagonist
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
INTS12 integrator complex subunit 12
ISM1 isthmin 1, angiogenesis inhibitor
ISOC2 isochorismatase domain containing 2
JOSD2 Josephin domain containing 2
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCNK5 potassium channel, two pore domain subfamily K, member 5
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KLHDC2 kelch domain containing 2
KLHL28 kelch-like family member 28
KRT26 keratin 26, type I
L2HGDH L-2-hydroxyglutarate dehydrogenase
LAMC2 laminin, gamma 2
LAMP5 lysosomal-associated membrane protein family, member 5
LARP1B La ribonucleoprotein domain family, member 1B
LINC00162 long intergenic non-protein coding RNA 162
LINC01559 long intergenic non-protein coding RNA 1559
LMF2 lipase maturation factor 2
LRR1 leucine rich repeat protein 1
MACROD2 MACRO domain containing 2
MAGEB2 melanoma antigen family B2
MANF mesencephalic astrocyte-derived neurotrophic factor
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
MCTP1 multiple C2 domains, transmembrane 1
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MID1IP1 MID1 interacting protein 1
MIPOL1 mirror-image polydactyly 1
MIS18BP1 MIS18 binding protein 1
MMP23B matrix metallopeptidase 23B
MRAP melanocortin 2 receptor accessory protein
MROH2B maestro heat-like repeat family member 2B
MSMO1 methylsterol monooxygenase 1
MTMR11 myotubularin related protein 11
MYDGF myeloid-derived growth factor
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
NANS N-acetylneuraminic acid synthase
NAPSA napsin A aspartic peptidase
NEMF nuclear export mediator factor
NIN ninein (GSK3B interacting protein)
NKX2-8 NK2 homeobox 8
NLGN4Y neuroligin 4, Y-linked
NNMT nicotinamide N-methyltransferase
NPC2 Niemann-Pick disease, type C2
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae)
NT5E 5'-nucleotidase, ecto (CD73)
NXF3 nuclear RNA export factor 3
NXT2 nuclear transport factor 2-like export factor 2
OCEL1 occludin/ELL domain containing 1
OCIAD2 OCIA domain containing 2
OR1F2P olfactory receptor, family 1, subfamily F, member 2, pseudogene
OR51B2 olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene)
OR51B4 olfactory receptor, family 51, subfamily B, member 4
OSBP2 oxysterol binding protein 2
OSTCP1 oligosaccharyltransferase complex subunit pseudogene 1
OXA1L oxidase (cytochrome c) assembly 1-like
PCDHGB6 protocadherin gamma subfamily B, 6
PGLS 6-phosphogluconolactonase
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PMM2 phosphomannomutase 2
PNKP polynucleotide kinase 3'-phosphatase
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PON2 paraoxonase 2
PORCN porcupine homolog (Drosophila)
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPP4R4 protein phosphatase 4, regulatory subunit 4
PPY pancreatic polypeptide
PRH1 proline-rich protein HaeIII subfamily 1
PRH2 proline-rich protein HaeIII subfamily 2
PROCR protein C receptor, endothelial
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PTPRH protein tyrosine phosphatase, receptor type, H
PYGL phosphorylase, glycogen, liver
RAB27B RAB27B, member RAS oncogene family
RABAC1 Rab acceptor 1 (prenylated)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAP1GAP RAP1 GTPase activating protein
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBFA ribosome binding factor A (putative)
RBMY1E RNA binding motif protein, Y-linked, family 1, member E
RCAN2 regulator of calcineurin 2
RGS3 regulator of G-protein signaling 3
RHOC ras homolog family member C
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPL13A ribosomal protein L13a
RPL18 ribosomal protein L18
RPL3 ribosomal protein L3
RPL36AL ribosomal protein L36a-like
RPS19BP1 ribosomal protein S19 binding protein 1
RPS27 ribosomal protein S27
RPS29 ribosomal protein S29
RPSAP52 ribosomal protein SA pseudogene 52
RRAS related RAS viral (r-ras) oncogene homolog
S100G S100 calcium binding protein G
SATL1 spermidine/spermine N1-acetyl transferase-like 1
SAV1 salvador family WW domain containing protein 1
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCT secretin
SDCBP2 syndecan binding protein (syntenin) 2
SEC23A Sec23 homolog A (S. cerevisiae)
SEC24D SEC24 family member D
SELM selenoprotein M
SEPW1 selenoprotein W, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFTPB surfactant protein B
SH2D3A SH2 domain containing 3A
SH3YL1 SH3 and SYLF domain containing 1
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SMTN smoothelin
SND1 staphylococcal nuclease and tudor domain containing 1
SNHG5 small nucleolar RNA host gene 5
SNX7 sorting nexin 7
SOS2 son of sevenless homolog 2 (Drosophila)
SPANXA2 SPANX family, member A2
SPANXB1 SPANX family, member B1
SPANXD SPANX family, member D
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae)
SPERT spermatid associated
SPINK4 serine peptidase inhibitor, Kazal type 4
SPON1 spondin 1, extracellular matrix protein
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRPX2 sushi-repeat containing protein, X-linked 2
SSTR5 somatostatin receptor 5
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STBD1 starch binding domain 1
STK32A serine/threonine kinase 32A
STYX serine/threonine/tyrosine interacting protein
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SURF4 surfeit 4
SYT5 synaptotagmin V
TAS2R1 taste receptor, type 2, member 1
TCERG1L transcription elongation regulator 1-like
TECTB tectorin beta
TLL2 tolloid-like 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMED7-TICAM2 TMED7-TICAM2 readthrough
TMEM105 transmembrane protein 105
TMEM191A transmembrane protein 191A (pseudogene)
TMEM205 transmembrane protein 205
TMEM27 transmembrane protein 27
TMEM37 transmembrane protein 37
TMEM92 transmembrane protein 92
TMX1 thioredoxin-related transmembrane protein 1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNNI3 troponin I type 3 (cardiac)
TNNT1 troponin T type 1 (skeletal, slow)
TP53TG1 TP53 target 1 (non-protein coding)
TPM4 tropomyosin 4
TPT1 tumor protein, translationally-controlled 1
TRAPPC6B trafficking protein particle complex 6B
TRIM61 tripartite motif containing 61
TSC22D1 TSC22 domain family, member 1
TSPAN1 tetraspanin 1
TSPAN3 tetraspanin 3
TSPAN5 tetraspanin 5
TTYH2 tweety family member 2
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
VCPKMT valosin containing protein lysine (K) methyltransferase
VILL villin-like
WNT10A wingless-type MMTV integration site family, member 10A
XDH xanthine dehydrogenase
ZBED2 zinc finger, BED-type containing 2
ZDHHC3 zinc finger, DHHC-type containing 3
ZNF542P zinc finger protein 542, pseudogene
ZNF581 zinc finger protein 581
ZNF583 zinc finger protein 583
ZNF593 zinc finger protein 593
ZYX zyxin

low expression

Symbol Name
NRF1 nuclear respiratory factor 1
TRIM25 tripartite motif containing 25