Lung squamous cell carcinoma_LUSC_TCGA-39-5030-01A-01R-1443-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

387 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-39-5030-01A-01R-1443-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADAM6 ADAM metallopeptidase domain 6 (pseudogene)
ADAMDEC1 ADAM-like, decysin 1
ADCY5 adenylate cyclase 5
ADGRB2 adhesion G protein-coupled receptor B2
ADGRG5 adhesion G protein-coupled receptor G5
ADM2 adrenomedullin 2
AFAP1 actin filament associated protein 1
AMOTL1 angiomotin like 1
AMPD1 adenosine monophosphate deaminase 1
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
AR androgen receptor
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASB6 ankyrin repeat and SOCS box containing 6
ATF7IP2 activating transcription factor 7 interacting protein 2
ATOH1 atonal homolog 1 (Drosophila)
BHLHA15 basic helix-loop-helix family, member a15
BMP2K BMP2 inducible kinase
BMPER BMP binding endothelial regulator
BRD3 bromodomain containing 3
C15ORF53 chromosome 15 open reading frame 53
C16ORF54 chromosome 16 open reading frame 54
C17ORF98 chromosome 17 open reading frame 98
C1QTNF1 C1q and tumor necrosis factor related protein 1
C2CD2 C2 calcium-dependent domain containing 2
C3ORF36 chromosome 3 open reading frame 36
C9ORF172 chromosome 9 open reading frame 172
C9ORF91 chromosome 9 open reading frame 91
CABS1 calcium-binding protein, spermatid-specific 1
CAMK1G calcium/calmodulin-dependent protein kinase IG
CAPN6 calpain 6
CCL19 chemokine (C-C motif) ligand 19
CCL5 chemokine (C-C motif) ligand 5
CCNF cyclin F
CCR2 chemokine (C-C motif) receptor 2
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR8 chemokine (C-C motif) receptor 8
CD180 CD180 molecule
CD1B CD1b molecule
CD2 CD2 molecule
CD200 CD200 molecule
CD247 CD247 molecule
CD27 CD27 molecule
CD28 CD28 molecule
CD38 CD38 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD5 CD5 molecule
CD6 CD6 molecule
CD7 CD7 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD84 CD84 molecule
CD96 CD96 molecule
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDON cell adhesion associated, oncogene regulated
CECR1 cat eye syndrome chromosome region, candidate 1
CEP128 centrosomal protein 128kDa
CHMP7 charged multivesicular body protein 7
CLEC1A C-type lectin domain family 1, member A
CLEC6A C-type lectin domain family 6, member A
CLIP3 CAP-GLY domain containing linker protein 3
CPNE5 copine V
CRB2 crumbs family member 2
CRYBA4 crystallin, beta A4
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR6 chemokine (C-X-C motif) receptor 6
CXORF21 chromosome X open reading frame 21
CYTH4 cytohesin 4
DCANP1 dendritic cell-associated nuclear protein
DERL3 derlin 3
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DNAH17 dynein, axonemal, heavy chain 17
DUPD1 dual specificity phosphatase and pro isomerase domain containing 1
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6
EOMES eomesodermin
EPHB2 EPH receptor B2
EPHB6 EPH receptor B6
EPSTI1 epithelial stromal interaction 1 (breast)
ETV6 ets variant 6
ETV7 ets variant 7
EXOC3L4 exocyst complex component 3-like 4
F5 coagulation factor V (proaccelerin, labile factor)
FAM117A family with sequence similarity 117, member A
FAM118B family with sequence similarity 118, member B
FAM46C family with sequence similarity 46, member C
FASLG Fas ligand (TNF superfamily, member 6)
FBXL13 F-box and leucine-rich repeat protein 13
FBXW5 F-box and WD repeat domain containing 5
FCRL4 Fc receptor-like 4
FDXACB1 ferredoxin-fold anticodon binding domain containing 1
FGD6 FYVE, RhoGEF and PH domain containing 6
FICD FIC domain containing
FKBP11 FK506 binding protein 11, 19 kDa
FNDC9 fibronectin type III domain containing 9
FOXP3 forkhead box P3
FOXP4 forkhead box P4
FPR3 formyl peptide receptor 3
FSTL4 follistatin-like 4
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FZD10 frizzled class receptor 10
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GAGE12F G antigen 12F
GAGE4 G antigen 4
GBP4 guanylate binding protein 4
GCSAM germinal center-associated, signaling and motility
GJD3 gap junction protein, delta 3, 31.9kDa
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GPR107 G protein-coupled receptor 107
GPR174 G protein-coupled receptor 174
GPR25 G protein-coupled receptor 25
GPR31 G protein-coupled receptor 31
GPR82 G protein-coupled receptor 82
GRIK1-AS1 GRIK1 antisense RNA 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
HAND2 heart and neural crest derivatives expressed 2
HCRTR1 hypocretin (orexin) receptor 1
HEPACAM hepatic and glial cell adhesion molecule
HEPN1 hepatocellular carcinoma, down-regulated 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-G major histocompatibility complex, class I, G
HLA-L major histocompatibility complex, class I, L (pseudogene)
HOXB13 homeobox B13
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HULC hepatocellular carcinoma up-regulated long non-coding RNA
ICAM3 intercellular adhesion molecule 3
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
IFIH1 interferon induced with helicase C domain 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNG interferon, gamma
IGFLR1 IGF-like family receptor 1
IGLL1 immunoglobulin lambda-like polypeptide 1
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IGSF6 immunoglobulin superfamily, member 6
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10RA interleukin 10 receptor, alpha
IL12RB1 interleukin 12 receptor, beta 1
IL16 interleukin 16
IL17F interleukin 17F
IL17REL interleukin 17 receptor E-like
IL2 interleukin 2
IL21 interleukin 21
IL21R interleukin 21 receptor
IL22RA2 interleukin 22 receptor, alpha 2
IL27RA interleukin 27 receptor, alpha
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL32 interleukin 32
IL4I1 interleukin 4 induced 1
INIP INTS3 and NABP interacting protein
IRF2 interferon regulatory factor 2
IRF4 interferon regulatory factor 4
ISLR immunoglobulin superfamily containing leucine-rich repeat
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB7 integrin, beta 7
ITM2C integral membrane protein 2C
IZUMO1R IZUMO1 receptor, JUNO
JAKMIP1 janus kinase and microtubule interacting protein 1
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KCTD17 potassium channel tetramerization domain containing 17
KEL Kell blood group, metallo-endopeptidase
KIAA0368 KIAA0368
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
KREMEN2 kringle containing transmembrane protein 2
KRT2 keratin 2, type II
KRTAP10-6 keratin associated protein 10-6
KRTAP4-12 keratin associated protein 4-12
LAG3 lymphocyte-activation gene 3
LAP3 leucine aminopeptidase 3
LAX1 lymphocyte transmembrane adaptor 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LGALS2 lectin, galactoside-binding, soluble, 2
LGALS9 lectin, galactoside-binding, soluble, 9
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LIME1 Lck interacting transmembrane adaptor 1
LINC00094 long intergenic non-protein coding RNA 94
LINC00304 long intergenic non-protein coding RNA 304
LMF1 lipase maturation factor 1
LMO4 LIM domain only 4
LMOD2 leiomodin 2 (cardiac)
LOC283731 uncharacterized LOC283731
LRRC2 leucine rich repeat containing 2
LRRC4B leucine rich repeat containing 4B
LRRC55 leucine rich repeat containing 55
LTA lymphotoxin alpha
LZTS1 leucine zipper, putative tumor suppressor 1
MAN2B1 mannosidase, alpha, class 2B, member 1
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAS1L MAS1 proto-oncogene like, G protein-coupled receptor
MED22 mediator complex subunit 22
MEF2BNB-MEF2B MEF2BNB-MEF2B readthrough
MEI1 meiosis inhibitor 1
MIXL1 Mix paired-like homeobox
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type
MMP12 matrix metallopeptidase 12
MOXD1 monooxygenase, DBH-like 1
MPPED2 metallophosphoesterase domain containing 2
MPZL1 myelin protein zero-like 1
NCK2 NCK adaptor protein 2
NCR2 natural cytotoxicity triggering receptor 2
NCS1 neuronal calcium sensor 1
NECAP2 NECAP endocytosis associated 2
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NFE2L3 nuclear factor, erythroid 2-like 3
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NINJ1 ninjurin 1
NMT2 N-myristoyltransferase 2
NOTCH1 notch 1
NPPC natriuretic peptide C
NUB1 negative regulator of ubiquitin-like proteins 1
OASL 2'-5'-oligoadenylate synthetase-like
OR2V2 olfactory receptor, family 2, subfamily V, member 2
OR7D2 olfactory receptor, family 7, subfamily D, member 2
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
P2RY8 purinergic receptor P2Y, G-protein coupled, 8
PABPC4L poly(A) binding protein, cytoplasmic 4-like
PAQR4 progestin and adipoQ receptor family member IV
PARM1 prostate androgen-regulated mucin-like protein 1
PATE2 prostate and testis expressed 2
PATE3 prostate and testis expressed 3
PDCD1 programmed cell death 1
PDE4B phosphodiesterase 4B, cAMP-specific
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIWIL4 piwi-like RNA-mediated gene silencing 4
PKDCC protein kinase domain containing, cytoplasmic
PLA2G2D phospholipase A2, group IID
PLA2G3 phospholipase A2, group III
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEK pleckstrin
PLXNC1 plexin C1
PNRC1 proline-rich nuclear receptor coactivator 1
PPBPP2 pro-platelet basic protein pseudogene 2
PPP1R18 protein phosphatase 1, regulatory subunit 18
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRDM10 PR domain containing 10
PROL1 proline rich, lacrimal 1
PROX2 prospero homeobox 2
PRR27 proline rich 27
PRR5L proline rich 5 like
PRSS36 protease, serine, 36
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPN7 protein tyrosine phosphatase, non-receptor type 7
PYCARD PYD and CARD domain containing
PYDC1 PYD (pyrin domain) containing 1
PYHIN1 pyrin and HIN domain family, member 1
RAI14 retinoic acid induced 14
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHBDL3 rhomboid, veinlet-like 3 (Drosophila)
RNF150 ring finger protein 150
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF4 ring finger protein 4
ROR2 receptor tyrosine kinase-like orphan receptor 2
RORB RAR-related orphan receptor B
S1PR3 sphingosine-1-phosphate receptor 3
SAMD9L sterile alpha motif domain containing 9-like
SASH3 SAM and SH3 domain containing 3
SEC16A SEC16 homolog A (S. cerevisiae)
SEC24D SEC24 family member D
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SELE selectin E
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH2B3 SH2B adaptor protein 3
SH2D2A SH2 domain containing 2A
SHISA2 shisa family member 2
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene)
SIRPG signal-regulatory protein gamma
SLA2 Src-like-adaptor 2
SLAMF1 signaling lymphocytic activation molecule family member 1
SLAMF6 SLAM family member 6
SLAMF7 SLAM family member 7
SLAMF8 SLAM family member 8
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLCO5A1 solute carrier organic anion transporter family, member 5A1
SLFN12L schlafen family member 12-like
SNX20 sorting nexin 20
SOCS1 suppressor of cytokine signaling 1
SOX8 SRY (sex determining region Y)-box 8
SP140 SP140 nuclear body protein
SPATS2 spermatogenesis associated, serine-rich 2
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPIN1 spindlin 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SSBP3 single stranded DNA binding protein 3
SSR4 signal sequence receptor, delta
SSTR3 somatostatin receptor 3
SSX3 synovial sarcoma, X breakpoint 3
SSX8 synovial sarcoma, X breakpoint 8
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STX17 syntaxin 17
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1
SURF4 surfeit 4
SYK spleen tyrosine kinase
SYNDIG1 synapse differentiation inducing 1
SYNPO2 synaptopodin 2
TAL2 T-cell acute lymphocytic leukemia 2
TAPBP TAP binding protein (tapasin)
TBX20 T-box 20
TBX21 T-box 21
TCF23 transcription factor 23
TEX11 testis expressed 11
TGFB3 transforming growth factor, beta 3
THY1 Thy-1 cell surface antigen
TIFA TRAF-interacting protein with forkhead-associated domain
TIFAB TRAF-interacting protein with forkhead-associated domain, family member B
TIGIT T cell immunoreceptor with Ig and ITIM domains
TLE4 transducin-like enhancer of split 4
TLR9 toll-like receptor 9
TMEM184C transmembrane protein 184C
TMEM200A transmembrane protein 200A
TMEM200C transmembrane protein 200C
TMEM244 transmembrane protein 244
TMIGD2 transmembrane and immunoglobulin domain containing 2
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TOR1B torsin family 1, member B (torsin B)
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1
TP73 tumor protein p73
TRAF1 TNF receptor-associated factor 1
TRAF2 TNF receptor-associated factor 2
TRAPPC3L trafficking protein particle complex 3-like
TRIM14 tripartite motif containing 14
TRIM32 tripartite motif containing 32
TRIM38 tripartite motif containing 38
TRIM69 tripartite motif containing 69
TSHR thyroid stimulating hormone receptor
TSPEAR thrombospondin-type laminin G domain and EAR repeats
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
TXNDC11 thioredoxin domain containing 11
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
UBASH3A ubiquitin associated and SH3 domain containing A
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1
UCK1 uridine-cytidine kinase 1
UNC5B unc-5 homolog B (C. elegans)
USP20 ubiquitin specific peptidase 20
UTS2 urotensin 2
UXS1 UDP-glucuronate decarboxylase 1
VASH2 vasohibin 2
VAV2 vav 2 guanine nucleotide exchange factor
VCAM1 vascular cell adhesion molecule 1
WIPF1 WAS/WASL interacting protein family, member 1
WNK2 WNK lysine deficient protein kinase 2
XBP1 X-box binding protein 1
ZBP1 Z-DNA binding protein 1
ZBTB46 zinc finger and BTB domain containing 46
ZFP37 ZFP37 zinc finger protein
ZNF677 zinc finger protein 677
ZNF683 zinc finger protein 683
ZNF79 zinc finger protein 79
ZNF827 zinc finger protein 827