Lung squamous cell carcinoma_LUSC_TCGA-39-5022-01A-21R-1820-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

360 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-39-5022-01A-21R-1820-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ABHD16A abhydrolase domain containing 16A
ACE2 angiotensin I converting enzyme 2
ACSF2 acyl-CoA synthetase family member 2
ACTBL2 actin, beta-like 2
ACY3 aminoacylase 3
ADAM6 ADAM metallopeptidase domain 6 (pseudogene)
ADGRG5 adhesion G protein-coupled receptor G5
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AKAP7 A kinase (PRKA) anchor protein 7
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2
AMPD1 adenosine monophosphate deaminase 1
APOL2 apolipoprotein L, 2
APOL3 apolipoprotein L, 3
APOL4 apolipoprotein L, 4
APOL6 apolipoprotein L, 6
ARMCX3 armadillo repeat containing, X-linked 3
ARRDC5 arrestin domain containing 5
ATP13A5 ATPase type 13A5
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
B2M beta-2-microglobulin
BACE2 beta-site APP-cleaving enzyme 2
BASP1 brain abundant, membrane attached signal protein 1
BATF basic leucine zipper transcription factor, ATF-like
BCO1 beta-carotene oxygenase 1
BSPRY B-box and SPRY domain containing
BST2 bone marrow stromal cell antigen 2
BTN3A1 butyrophilin, subfamily 3, member A1
BTN3A2 butyrophilin, subfamily 3, member A2
BTN3A3 butyrophilin, subfamily 3, member A3
C11ORF94 chromosome 11 open reading frame 94
C1GALT1C1 C1GALT1-specific chaperone 1
C1ORF100 chromosome 1 open reading frame 100
C1S complement component 1, s subcomponent
C2 complement component 2
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
C4ORF50 chromosome 4 open reading frame 50
C5ORF56 chromosome 5 open reading frame 56
C8ORF22 chromosome 8 open reading frame 22
C8ORF48 chromosome 8 open reading frame 48
CA10 carbonic anhydrase X
CA3 carbonic anhydrase III
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCL5 chemokine (C-C motif) ligand 5
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD160 CD160 molecule
CD180 CD180 molecule
CD2 CD2 molecule
CD247 CD247 molecule
CD27 CD27 molecule
CD38 CD38 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD6 CD6 molecule
CD7 CD7 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD79A CD79a molecule, immunoglobulin-associated alpha
CD8A CD8a molecule
CD96 CD96 molecule
CDC42SE2 CDC42 small effector 2
CDYL2 chromodomain protein, Y-like 2
CECR1 cat eye syndrome chromosome region, candidate 1
CFB complement factor B
CFHR1 complement factor H-related 1
CGA glycoprotein hormones, alpha polypeptide
CHRDL2 chordin-like 2
CIDEA cell death-inducing DFFA-like effector a
CLDN22 claudin 22
CLEC3A C-type lectin domain family 3, member A
CLU clusterin
CP ceruloplasmin (ferroxidase)
CPNE5 copine V
CR1L complement component (3b/4b) receptor 1-like
CRTAM cytotoxic and regulatory T cell molecule
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTSS cathepsin S
CTSW cathepsin W
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR6 chemokine (C-X-C motif) receptor 6
CXORF40A chromosome X open reading frame 40A
CYB561D2 cytochrome b561 family, member D2
CYLD cylindromatosis (turban tumor syndrome)
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP4X1 cytochrome P450, family 4, subfamily X, polypeptide 1
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1
CYTH4 cytohesin 4
CYTIP cytohesin 1 interacting protein
DERL3 derlin 3
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DPF3 D4, zinc and double PHD fingers, family 3
DSEL dermatan sulfate epimerase-like
ECEL1 endothelin converting enzyme-like 1
EOMES eomesodermin
ERAP1 endoplasmic reticulum aminopeptidase 1
ETNPPL ethanolamine-phosphate phospho-lyase
ETV7 ets variant 7
EVI2B ecotropic viral integration site 2B
FAM107B family with sequence similarity 107, member B
FAM26F family with sequence similarity 26, member F
FAM46C family with sequence similarity 46, member C
FASLG Fas ligand (TNF superfamily, member 6)
FBXO6 F-box protein 6
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCGBP Fc fragment of IgG binding protein
FCGR1C Fc fragment of IgG, high affinity Ic, receptor (CD64), pseudogene
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FCRL5 Fc receptor-like 5
FCRLA Fc receptor-like A
FCRLB Fc receptor-like B
FICD FIC domain containing
FKBP11 FK506 binding protein 11, 19 kDa
FLT3 fms-related tyrosine kinase 3
FOXC2 forkhead box C2
FUK fucokinase
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6
GBP1 guanylate binding protein 1, interferon-inducible
GBP2 guanylate binding protein 2, interferon-inducible
GBP3 guanylate binding protein 3
GBP4 guanylate binding protein 4
GBP5 guanylate binding protein 5
GBP7 guanylate binding protein 7
GCH1 GTP cyclohydrolase 1
GFI1 growth factor independent 1 transcription repressor
GIMAP2 GTPase, IMAP family member 2
GJD3 gap junction protein, delta 3, 31.9kDa
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
GMPPB GDP-mannose pyrophosphorylase B
GPR150 G protein-coupled receptor 150
GPR25 G protein-coupled receptor 25
GPR31 G protein-coupled receptor 31
GPR84 G protein-coupled receptor 84
GRIP2 glutamate receptor interacting protein 2
GSTK1 glutathione S-transferase kappa 1
GUSB glucuronidase, beta
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
HCP5 HLA complex P5 (non-protein coding)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HGD homogentisate 1,2-dioxygenase
HIST1H4H histone cluster 1, H4h
HLA-A major histocompatibility complex, class I, A
HLA-C major histocompatibility complex, class I, C
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-H major histocompatibility complex, class I, H (pseudogene)
HLA-L major histocompatibility complex, class I, L (pseudogene)
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
ICAM3 intercellular adhesion molecule 3
IDO1 indoleamine 2,3-dioxygenase 1
IFNG interferon, gamma
IGLL1 immunoglobulin lambda-like polypeptide 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10RA interleukin 10 receptor, alpha
IL12RB1 interleukin 12 receptor, beta 1
IL17F interleukin 17F
IL18BP interleukin 18 binding protein
IL21 interleukin 21
IL21R interleukin 21 receptor
IL26 interleukin 26
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL5RA interleukin 5 receptor, alpha
IL9R interleukin 9 receptor
INHA inhibin, alpha
IRF1 interferon regulatory factor 1
IRF4 interferon regulatory factor 4
IRX6 iroquois homeobox 6
ITGAD integrin, alpha D
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
ITGB7 integrin, beta 7
ITM2C integral membrane protein 2C
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KCNQ1DN KCNQ1 downstream neighbor (non-protein coding)
KIAA0040 KIAA0040
KIAA0125 KIAA0125
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KLHDC7B kelch domain containing 7B
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KRTAP20-2 keratin associated protein 20-2
LAG3 lymphocyte-activation gene 3
LAP3 leucine aminopeptidase 3
LAX1 lymphocyte transmembrane adaptor 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2
LINC00473 long intergenic non-protein coding RNA 473
LINC01554 long intergenic non-protein coding RNA 1554
LINGO4 leucine rich repeat and Ig domain containing 4
LOC100133669 uncharacterized LOC100133669
LOC100240735 uncharacterized LOC100240735
LOC285629 uncharacterized LOC285629
LOC285696 uncharacterized LOC285696
LOC389705 chromosome 4 open reading frame 27 pseudogene
LRRN2 leucine rich repeat neuronal 2
LY9 lymphocyte antigen 9
MAPK4 mitogen-activated protein kinase 4
MEI1 meiosis inhibitor 1
MOCOS molybdenum cofactor sulfurase
MSRB2 methionine sulfoxide reductase B2
MUC13 mucin 13, cell surface associated
MYDGF myeloid-derived growth factor
MYO7A myosin VIIA
NCF1 neutrophil cytosolic factor 1
NCF1C neutrophil cytosolic factor 1C pseudogene
NLGN4X neuroligin 4, X-linked
NLRP5 NLR family, pyrin domain containing 5
NOVA1 neuro-oncological ventral antigen 1
NPY1R neuropeptide Y receptor Y1
NRG2 neuregulin 2
NTNG2 netrin G2
NUGGC nuclear GTPase, germinal center associated
NXPE4 neurexophilin and PC-esterase domain family, member 4
OLFM4 olfactomedin 4
OR1F1 olfactory receptor, family 1, subfamily F, member 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
P2RY8 purinergic receptor P2Y, G-protein coupled, 8
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDCD1 programmed cell death 1
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDE8B phosphodiesterase 8B
PDX1 pancreatic and duodenal homeobox 1
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIGR polymeric immunoglobulin receptor
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLCL2 phospholipase C-like 2
POU2AF1 POU class 2 associating factor 1
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRDM1 PR domain containing 1, with ZNF domain
PROX2 prospero homeobox 2
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PTGDR prostaglandin D2 receptor (DP)
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PYHIN1 pyrin and HIN domain family, member 1
RAB20 RAB20, member RAS oncogene family
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RCN1 reticulocalbin 1, EF-hand calcium binding domain
REG1A regenerating islet-derived 1 alpha
RHOH ras homolog family member H
RHOU ras homolog family member U
RNF114 ring finger protein 114
RNF182 ring finger protein 182
RNF213 ring finger protein 213
RORC RAR-related orphan receptor C
SAA1 serum amyloid A1
SCARA3 scavenger receptor class A, member 3
SEC16B SEC16 homolog B (S. cerevisiae)
SEC24A SEC24 family member A
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERHL2 serine hydrolase-like 2
SFMBT2 Scm-like with four mbt domains 2
SIL1 SIL1 nucleotide exchange factor
SIRPG signal-regulatory protein gamma
SLA2 Src-like-adaptor 2
SLAMF1 signaling lymphocytic activation molecule family member 1
SLAMF6 SLAM family member 6
SLAMF7 SLAM family member 7
SLAMF8 SLAM family member 8
SLC16A14 solute carrier family 16, member 14
SLC16A6 solute carrier family 16, member 6
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC35A4 solute carrier family 35, member A4
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7
SMOC1 SPARC related modular calcium binding 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SORD sorbitol dehydrogenase
SOWAHD sosondowah ankyrin repeat domain family member D
SP140 SP140 nuclear body protein
SP6 Sp6 transcription factor
SPAG4 sperm associated antigen 4
SPTA1 spectrin, alpha, erythrocytic 1
SSR4 signal sequence receptor, delta
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STS steroid sulfatase (microsomal), isozyme S
SV2C synaptic vesicle glycoprotein 2C
SYT10 synaptotagmin X
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAGAP T-cell activation RhoGTPase activating protein
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TAPBPL TAP binding protein-like
TAS1R3 taste receptor, type 1, member 3
TBXAS1 thromboxane A synthase 1 (platelet)
TCF23 transcription factor 23
TCN2 transcobalamin II
TIGIT T cell immunoreceptor with Ig and ITIM domains
TLR9 toll-like receptor 9
TMED9 transmembrane emp24 protein transport domain containing 9
TMEM205 transmembrane protein 205
TMEM229B transmembrane protein 229B
TMEM244 transmembrane protein 244
TMPRSS3 transmembrane protease, serine 3
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TP53INP1 tumor protein p53 inducible nuclear protein 1
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
TRABD2A TraB domain containing 2A
TRIM31 tripartite motif containing 31
TUSC3 tumor suppressor candidate 3
TVP23A trans-golgi network vesicle protein 23 homolog A (S. cerevisiae)
TXNDC11 thioredoxin domain containing 11
TXNDC15 thioredoxin domain containing 15
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
UBASH3A ubiquitin associated and SH3 domain containing A
UBD ubiquitin D
UBE2J1 ubiquitin-conjugating enzyme E2, J1
USP48 ubiquitin specific peptidase 48
VENTXP7 VENT homeobox pseudogene 7
VMO1 vitelline membrane outer layer 1 homolog (chicken)
WARS tryptophanyl-tRNA synthetase
WDR64 WD repeat domain 64
WIPF1 WAS/WASL interacting protein family, member 1
XBP1 X-box binding protein 1
ZBP1 Z-DNA binding protein 1
ZFAT zinc finger and AT hook domain containing
ZNF648 zinc finger protein 648
ZNF672 zinc finger protein 672
ZNF683 zinc finger protein 683