Lung squamous cell carcinoma_LUSC_TCGA-39-5016-01A-01R-1443-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

388 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-39-5016-01A-01R-1443-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABHD11 abhydrolase domain containing 11
ABHD17B abhydrolase domain containing 17B
ACKR3 atypical chemokine receptor 3
ACSL3 acyl-CoA synthetase long-chain family member 3
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADCY3 adenylate cyclase 3
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ADSS adenylosuccinate synthase
AFF2 AF4/FMR2 family, member 2
AGFG1 ArfGAP with FG repeats 1
AHR aryl hydrocarbon receptor
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AKR1C6P aldo-keto reductase family 1, member C6, pseudogene
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMMECR1L AMMECR1-like
ANAPC1 anaphase promoting complex subunit 1
APOBEC3D apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
ARMC10 armadillo repeat containing 10
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ASL argininosuccinate lyase
ATG9A autophagy related 9A
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCAS3 breast carcinoma amplified sequence 3
BCL7B B-cell CLL/lymphoma 7B
BCYRN1 brain cytoplasmic RNA 1
BRI3 brain protein I3
C20ORF24 chromosome 20 open reading frame 24
C21ORF62-AS1 C21orf62 antisense RNA 1
C4ORF51 chromosome 4 open reading frame 51
C6ORF10 chromosome 6 open reading frame 10
CALN1 calneuron 1
CARD11 caspase recruitment domain family, member 11
CCDC122 coiled-coil domain containing 122
CCDC160 coiled-coil domain containing 160
CCDC169 coiled-coil domain containing 169
CCNYL1 cyclin Y-like 1
CCSER1 coiled-coil serine-rich protein 1
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD274 CD274 molecule
CD46 CD46 molecule, complement regulatory protein
CDC14B cell division cycle 14B
CDC14C cell division cycle 14C
CDR2L cerebellar degeneration-related protein 2-like
CEP44 centrosomal protein 44kDa
CFHR3 complement factor H-related 3
CGREF1 cell growth regulator with EF-hand domain 1
CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5
CIART circadian associated repressor of transcription
CLDN1 claudin 1
CLINT1 clathrin interactor 1
CLIP2 CAP-GLY domain containing linker protein 2
CNOT11 CCR4-NOT transcription complex, subunit 11
COA6 cytochrome c oxidase assembly factor 6
COG2 component of oligomeric golgi complex 2
COIL coilin
COLGALT1 collagen beta(1-O)galactosyltransferase 1
COPS6 COP9 signalosome subunit 6
COPS7B COP9 signalosome subunit 7B
COPS8 COP9 signalosome subunit 8
COQ10B coenzyme Q10 homolog B (S. cerevisiae)
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CPXM2 carboxypeptidase X (M14 family), member 2
CRCP CGRP receptor component
CRTAP cartilage associated protein
CSTL1 cystatin-like 1
DBF4 DBF4 zinc finger
DCAF7 DDB1 and CUL4 associated factor 7
DCAKD dephospho-CoA kinase domain containing
DESI2 desumoylating isopeptidase 2
DHRSX dehydrogenase/reductase (SDR family) X-linked
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DIRAS2 DIRAS family, GTP-binding RAS-like 2
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2
DNAJC30 DnaJ (Hsp40) homolog, subfamily C, member 30
DNPEP aspartyl aminopeptidase
DPY19L2P1 DPY19L2 pseudogene 1
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DUS1L dihydrouridine synthase 1-like (S. cerevisiae)
E2F6 E2F transcription factor 6
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EIF4H eukaryotic translation initiation factor 4H
ELF1 E74-like factor 1 (ets domain transcription factor)
ELOVL6 ELOVL fatty acid elongase 6
ENOX2 ecto-NOX disulfide-thiol exchanger 2
ERI1 exoribonuclease 1
EVA1C eva-1 homolog C (C. elegans)
EXOC1 exocyst complex component 1
FAM117B family with sequence similarity 117, member B
FAM134A family with sequence similarity 134, member A
FAM185A family with sequence similarity 185, member A
FAM206A family with sequence similarity 206, member A
FARSB phenylalanyl-tRNA synthetase, beta subunit
FASTKD2 FAST kinase domains 2
FBN2 fibrillin 2
FBXO7 F-box protein 7
FECH ferrochelatase
FGFBP1 fibroblast growth factor binding protein 1
FGFR2 fibroblast growth factor receptor 2
FLYWCH1 FLYWCH-type zinc finger 1
FOXO4 forkhead box O4
FOXQ1 forkhead box Q1
FPGS folylpolyglutamate synthase
FRMD4B FERM domain containing 4B
FXN frataxin
FXYD3 FXYD domain containing ion transport regulator 3
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GATS GATS, stromal antigen 3 opposite strand
GATSL2 GATS protein-like 2
GDA guanine deaminase
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1
GGPS1 geranylgeranyl diphosphate synthase 1
GLIPR1L2 GLI pathogenesis-related 1 like 2
GLRA3 glycine receptor, alpha 3
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNPAT glyceronephosphate O-acyltransferase
GNPDA1 glucosamine-6-phosphate deaminase 1
GPC1 glypican 1
GPR137B G protein-coupled receptor 137B
GPR63 G protein-coupled receptor 63
GPR89A G protein-coupled receptor 89A
GSTCD glutathione S-transferase, C-terminal domain containing
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTM3 glutathione S-transferase mu 3 (brain)
GTF2I general transcription factor IIi
GTF2IP1 general transcription factor IIi pseudogene 1
GTF2IRD2 GTF2I repeat domain containing 2
GTF2IRD2B GTF2I repeat domain containing 2B
GTPBP10 GTP-binding protein 10 (putative)
GUF1 GUF1 GTPase homolog (S. cerevisiae)
GULP1 GULP, engulfment adaptor PTB domain containing 1
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HBP1 HMG-box transcription factor 1
HHEX hematopoietically expressed homeobox
HIATL1 hippocampus abundant transcript-like 1
HM13 histocompatibility (minor) 13
HORMAD1 HORMA domain containing 1
HOXA1 homeobox A1
HOXC8 homeobox C8
HOXD8 homeobox D8
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HS6ST2 heparan sulfate 6-O-sulfotransferase 2
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IARS isoleucyl-tRNA synthetase
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IFI35 interferon-induced protein 35
IFT22 intraflagellar transport 22
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL15RA interleukin 15 receptor, alpha
IL17A interleukin 17A
IRF2 interferon regulatory factor 2
ISCA1 iron-sulfur cluster assembly 1
ITGA6 integrin, alpha 6
JMJD4 jumonji domain containing 4
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KDSR 3-ketodihydrosphingosine reductase
KEAP1 kelch-like ECH-associated protein 1
KIAA1804 mixed lineage kinase 4
KLF5 Kruppel-like factor 5 (intestinal)
KRCC1 lysine-rich coiled-coil 1
KRT15 keratin 15, type I
KRT19 keratin 19, type I
LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
LARGE like-glycosyltransferase
LDAH lipid droplet associated hydrolase
LIMK1 LIM domain kinase 1
LIN54 lin-54 DREAM MuvB core complex component
LIPT1 lipoyltransferase 1
LOC100130691 uncharacterized LOC100130691
LOC407835 mitogen-activated protein kinase kinase 2 pseudogene
LONRF1 LON peptidase N-terminal domain and ring finger 1
LOXL4 lysyl oxidase-like 4
LRRC37B leucine rich repeat containing 37B
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MARS2 methionyl-tRNA synthetase 2, mitochondrial
MBD2 methyl-CpG binding domain protein 2
MERTK MER proto-oncogene, tyrosine kinase
METAP1D methionyl aminopeptidase type 1D (mitochondrial)
METTL21A methyltransferase like 21A
METTL2A methyltransferase like 2A
MFF mitochondrial fission factor
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MGC72080 MGC72080 pseudogene
MGST2 microsomal glutathione S-transferase 2
MITD1 MIT, microtubule interacting and transport, domain containing 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type
MOB4 MOB family member 4, phocein
MPPE1 metallophosphoesterase 1
MREG melanoregulin
MRPL10 mitochondrial ribosomal protein L10
MRPL12 mitochondrial ribosomal protein L12
MRPL44 mitochondrial ribosomal protein L44
MRPS9 mitochondrial ribosomal protein S9
MVB12A multivesicular body subunit 12A
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NCR2 natural cytotoxicity triggering receptor 2
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
NEK3 NIMA-related kinase 3
NFE2L2 nuclear factor, erythroid 2-like 2
NHLRC3 NHL repeat containing 3
NIFK nucleolar protein interacting with the FHA domain of MKI67
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NLGN1 neuroligin 1
NMRK1 nicotinamide riboside kinase 1
NOA1 nitric oxide associated 1
NR1D1 nuclear receptor subfamily 1, group D, member 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NT5C3B 5'-nucleotidase, cytosolic IIIB
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
OR10R2 olfactory receptor, family 10, subfamily R, member 2
OR13C8 olfactory receptor, family 13, subfamily C, member 8
OR6C70 olfactory receptor, family 6, subfamily C, member 70
OR6M1 olfactory receptor, family 6, subfamily M, member 1
ORC5 origin recognition complex, subunit 5
ORMDL1 ORMDL sphingolipid biosynthesis regulator 1
OSBPL6 oxysterol binding protein-like 6
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
OXR1 oxidation resistance 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PAPPA2 pappalysin 2
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCTP phosphatidylcholine transfer protein
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PGLS 6-phosphogluconolactonase
PHTF2 putative homeodomain transcription factor 2
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PMPCB peptidase (mitochondrial processing) beta
PMS2P1 postmeiotic segregation increased 2 pseudogene 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PMS2P4 postmeiotic segregation increased 2 pseudogene 4
PMS2P5 postmeiotic segregation increased 2 pseudogene 5
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
POMZP3 POM121 and ZP3 fusion
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
PPAT phosphoribosyl pyrophosphate amidotransferase
PPID peptidylprolyl isomerase D
PPIL3 peptidylprolyl isomerase (cyclophilin)-like 3
PRDX6 peroxiredoxin 6
PRIMPOL primase and polymerase (DNA-directed)
PRKCI protein kinase C, iota
PRR23C proline rich 23C
PSAT1 phosphoserine aminotransferase 1
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PTDSS1 phosphatidylserine synthase 1
PTER phosphotriesterase related
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PUS7 pseudouridylate synthase 7 (putative)
RABL2A RAB, member of RAS oncogene family-like 2A
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RFC2 replication factor C (activator 1) 2, 40kDa
RFT1 RFT1 homolog (S. cerevisiae)
RHBDD1 rhomboid domain containing 1
RINT1 RAD50 interactor 1
RNF149 ring finger protein 149
RNF175 ring finger protein 175
RNF25 ring finger protein 25
RNFT1 ring finger protein, transmembrane 1
RPE ribulose-5-phosphate-3-epimerase
RPL22L1 ribosomal protein L22-like 1
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RSBN1L round spermatid basic protein 1-like
S1PR5 sphingosine-1-phosphate receptor 5
SBDSP1 Shwachman-Bodian-Diamond syndrome pseudogene 1
SCLY selenocysteine lyase
SEC14L4 SEC14-like 4 (S. cerevisiae)
SEPT10 septin 10
SEPT2 septin 2
SFT2D3 SFT2 domain containing 3
SGCE sarcoglycan, epsilon
SGPP2 sphingosine-1-phosphate phosphatase 2
SHFM1 split hand/foot malformation (ectrodactyly) type 1
SLC10A7 solute carrier family 10, member 7
SLC25A40 solute carrier family 25, member 40
SLC25A43 solute carrier family 25, member 43
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC35F5 solute carrier family 35, member F5
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC39A10 solute carrier family 39 (zinc transporter), member 10
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMG8 SMG8 nonsense mediated mRNA decay factor
SNX12 sorting nexin 12
SOAT1 sterol O-acyltransferase 1
SPAG16 sperm associated antigen 16
SPATA16 spermatogenesis associated 16
SPERT spermatid associated
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SQSTM1 sequestosome 1
SRI sorcin
SRP72 signal recognition particle 72kDa
SRPK2 SRSF protein kinase 2
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STARD7 StAR-related lipid transfer (START) domain containing 7
STK16 serine/threonine kinase 16
STRADB STE20-related kinase adaptor beta
SYCE1 synaptonemal complex central element protein 1
SYPL1 synaptophysin-like 1
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TBCE tubulin folding cofactor E
TBL1X transducin (beta)-like 1X-linked
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBL2 transducin (beta)-like 2
TDRD5 tudor domain containing 5
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFB2M transcription factor B2, mitochondrial
THAP4 THAP domain containing 4
TKT transketolase
TLE4 transducin-like enhancer of split 4
TM9SF4 transmembrane 9 superfamily protein member 4
TMEM116 transmembrane protein 116
TMEM117 transmembrane protein 117
TMEM144 transmembrane protein 144
TMEM177 transmembrane protein 177
TMEM182 transmembrane protein 182
TMEM185A transmembrane protein 185A
TMEM192 transmembrane protein 192
TMEM243 transmembrane protein 243, mitochondrial
TMEM248 transmembrane protein 248
TMEM38B transmembrane protein 38B
TMEM60 transmembrane protein 60
TMEM87B transmembrane protein 87B
TMX3 thioredoxin-related transmembrane protein 3
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TP53TG1 TP53 target 1 (non-protein coding)
TPST1 tyrosylprotein sulfotransferase 1
TRIB3 tribbles pseudokinase 3
TRIM37 tripartite motif containing 37
TRIM4 tripartite motif containing 4
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae)
TSC22D4 TSC22 domain family, member 4
TSN translin
TSPAN18 tetraspanin 18
TTL tubulin tyrosine ligase
TTYH2 tweety family member 2
TUBD1 tubulin, delta 1
TUBGCP2 tubulin, gamma complex associated protein 2
TYW5 tRNA-yW synthesizing protein 5
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBE2F ubiquitin-conjugating enzyme E2F (putative)
UBQLN1 ubiquilin 1
UBXN2A UBX domain protein 2A
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
UGT8 UDP glycosyltransferase 8
UNC50 unc-50 homolog (C. elegans)
UXS1 UDP-glucuronate decarboxylase 1
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1
WBSCR16 Williams-Beuren syndrome chromosome region 16
WBSCR22 Williams Beuren syndrome chromosome region 22
WBSCR28 Williams-Beuren syndrome chromosome region 28
WDR41 WD repeat domain 41
XKR6 XK, Kell blood group complex subunit-related family, member 6
YIPF4 Yip1 domain family, member 4
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZC3H15 zinc finger CCCH-type containing 15
ZC3H8 zinc finger CCCH-type containing 8
ZDBF2 zinc finger, DBF-type containing 2
ZFAND2B zinc finger, AN1-type domain 2B
ZP3 zona pellucida glycoprotein 3 (sperm receptor)