Lung squamous cell carcinoma_LUSC_TCGA-34-5239-01A-21R-1820-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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432 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-34-5239-01A-21R-1820-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACTA2 actin, alpha 2, smooth muscle, aorta
ADAM8 ADAM metallopeptidase domain 8
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional)
ADGRG2 adhesion G protein-coupled receptor G2
AEBP1 AE binding protein 1
AFAP1 actin filament associated protein 1
AFAP1L2 actin filament associated protein 1-like 2
AGTPBP1 ATP/GTP binding protein 1
AK8 adenylate kinase 8
AKAP11 A kinase (PRKA) anchor protein 11
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALPK1 alpha-kinase 1
ALPK2 alpha-kinase 2
ANGPTL2 angiopoietin-like 2
ANKH ANKH inorganic pyrophosphate transport regulator
ANKLE2 ankyrin repeat and LEM domain containing 2
ANKRD22 ankyrin repeat domain 22
ANKRD29 ankyrin repeat domain 29
ANKRD36BP1 ankyrin repeat domain 36B pseudogene 1
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6
ANO9 anoctamin 9
ANTXR1 anthrax toxin receptor 1
AR androgen receptor
ARL17B ADP-ribosylation factor-like 17B
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASB6 ankyrin repeat and SOCS box containing 6
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATF7 activating transcription factor 7
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
B3GAT2 beta-1,3-glucuronyltransferase 2
BBS1 Bardet-Biedl syndrome 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL9 B-cell CLL/lymphoma 9
BMP2K BMP2 inducible kinase
BRD3 bromodomain containing 3
BREA2 breast cancer estrogen-induced apoptosis 2
BTNL9 butyrophilin-like 9
C11ORF42 chromosome 11 open reading frame 42
C2ORF54 chromosome 2 open reading frame 54
C7ORF34 chromosome 7 open reading frame 34
C7ORF66 chromosome 7 open reading frame 66
C8G complement component 8, gamma polypeptide
C9ORF170 chromosome 9 open reading frame 170
CAMK1G calcium/calmodulin-dependent protein kinase IG
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
CAPRIN1 cell cycle associated protein 1
CARS cysteinyl-tRNA synthetase
CBLN2 cerebellin 2 precursor
CBX5 chromobox homolog 5
CCDC25 coiled-coil domain containing 25
CCL27 chemokine (C-C motif) ligand 27
CCND1 cyclin D1
CCNI2 cyclin I family, member 2
CD1A CD1a molecule
CD1E CD1e molecule
CD207 CD207 molecule, langerin
CDC14A cell division cycle 14A
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH20 cadherin 20, type 2
CDH23 cadherin-related 23
CDK18 cyclin-dependent kinase 18
CDKN2A-AS1 CDKN2A antisense RNA 1 (head to head)
CDKN2B-AS1 CDKN2B antisense RNA 1
CDRT4 CMT1A duplicated region transcript 4
CEP135 centrosomal protein 135kDa
CEP170 centrosomal protein 170kDa
CHD3 chromodomain helicase DNA binding protein 3
CHDH choline dehydrogenase
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CILP2 cartilage intermediate layer protein 2
CLDN10 claudin 10
CLEC1A C-type lectin domain family 1, member A
CLIP3 CAP-GLY domain containing linker protein 3
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COL15A1 collagen, type XV, alpha 1
COL4A4 collagen, type IV, alpha 4
COL8A1 collagen, type VIII, alpha 1
COL8A2 collagen, type VIII, alpha 2
COMP cartilage oligomeric matrix protein
CORIN corin, serine peptidase
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CPT1A carnitine palmitoyltransferase 1A (liver)
CRB2 crumbs family member 2
CREB3L1 cAMP responsive element binding protein 3-like 1
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSRNP3 cysteine-serine-rich nuclear protein 3
CTNND1 catenin (cadherin-associated protein), delta 1
CYP1B1-AS1 CYP1B1 antisense RNA 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DAAM1 dishevelled associated activator of morphogenesis 1
DCHS2 dachsous cadherin-related 2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DEFB131 defensin, beta 131
DGKZ diacylglycerol kinase, zeta
DMP1 dentin matrix acidic phosphoprotein 1
DOC2B double C2-like domains, beta
DRGX dorsal root ganglia homeobox
DSE dermatan sulfate epimerase
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
DZIP1 DAZ interacting zinc finger protein 1
EEF1G eukaryotic translation elongation factor 1 gamma
EEF2 eukaryotic translation elongation factor 2
EGFLAM EGF-like, fibronectin type III and laminin G domains
EIF3F eukaryotic translation initiation factor 3, subunit F
ELN elastin
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC6L2 excision repair cross-complementation group 6-like 2
ERI1 exoribonuclease 1
ETV3 ets variant 3
ETV6 ets variant 6
FADD Fas (TNFRSF6)-associated via death domain
FADS1 fatty acid desaturase 1
FAM65C family with sequence similarity 65, member C
FANCC Fanconi anemia, complementation group C
FAS Fas cell surface death receptor
FBN1 fibrillin 1
FBXW2 F-box and WD repeat domain containing 2
FBXW5 F-box and WD repeat domain containing 5
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCGBP Fc fragment of IgG binding protein
FERMT1 fermitin family member 1
FGD6 FYVE, RhoGEF and PH domain containing 6
FGF1 fibroblast growth factor 1 (acidic)
FKBP1A FK506 binding protein 1A, 12kDa
FMOD fibromodulin
FNDC1 fibronectin type III domain containing 1
FOXN1 forkhead box N1
FOXP1 forkhead box P1
FOXP4 forkhead box P4
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18
GAS6 growth arrest-specific 6
GATAD2B GATA zinc finger domain containing 2B
GCSAM germinal center-associated, signaling and motility
GJA3 gap junction protein, alpha 3, 46kDa
GMEB1 glucocorticoid modulatory element binding protein 1
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNRHR2 gonadotropin-releasing hormone (type 2) receptor 2, pseudogene
GORAB golgin, RAB6-interacting
GPR107 G protein-coupled receptor 107
GPR137 G protein-coupled receptor 137
GPR21 G protein-coupled receptor 21
GPR55 G protein-coupled receptor 55
GREM1 gremlin 1, DAN family BMP antagonist
GRIK1-AS1 GRIK1 antisense RNA 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GSTCD glutathione S-transferase, C-terminal domain containing
HCRTR1 hypocretin (orexin) receptor 1
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HFE hemochromatosis
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular)
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IL11RA interleukin 11 receptor, alpha
IL17REL interleukin 17 receptor E-like
IL1R2 interleukin 1 receptor, type II
IL22RA2 interleukin 22 receptor, alpha 2
IL27RA interleukin 27 receptor, alpha
IL2RG interleukin 2 receptor, gamma
IL9R interleukin 9 receptor
IMPG1 interphotoreceptor matrix proteoglycan 1
INO80 INO80 complex subunit
INSL3 insulin-like 3 (Leydig cell)
INSRR insulin receptor-related receptor
INTS9 integrator complex subunit 9
IPO7 importin 7
ISL1 ISL LIM homeobox 1
ISM1 isthmin 1, angiogenesis inhibitor
ITGA11 integrin, alpha 11
ITGAV integrin, alpha V
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
ITPKB inositol-trisphosphate 3-kinase B
ITSN2 intersectin 2
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KBTBD6 kelch repeat and BTB (POZ) domain containing 6
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCTD4 potassium channel tetramerization domain containing 4
KEL Kell blood group, metallo-endopeptidase
KIAA0368 KIAA0368
KIAA1147 KIAA1147
KIAA1211 KIAA1211
KIAA1549L KIAA1549-like
KITLG KIT ligand
KLHL12 kelch-like family member 12
KREMEN1 kringle containing transmembrane protein 1
KRT2 keratin 2, type II
KRT73 keratin 73, type II
KRTAP10-2 keratin associated protein 10-2
KRTAP12-4 keratin associated protein 12-4
KRTAP2-2 keratin associated protein 2-2
KSR1 kinase suppressor of ras 1
LDLRAD3 low density lipoprotein receptor class A domain containing 3
LEMD1 LEM domain containing 1
LGI2 leucine-rich repeat LGI family, member 2
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LHX2 LIM homeobox 2
LIFR leukemia inhibitory factor receptor alpha
LINC00028 long intergenic non-protein coding RNA 28
LINC00310 long intergenic non-protein coding RNA 310
LINC00515 long intergenic non-protein coding RNA 515
LMAN1 lectin, mannose-binding, 1
LOC100192426 uncharacterized LOC100192426
LOC284023 uncharacterized LOC284023
LRFN2 leucine rich repeat and fibronectin type III domain containing 2
LRRC2 leucine rich repeat containing 2
LSAMP limbic system-associated membrane protein
LTBP1 latent transforming growth factor beta binding protein 1
LTBP2 latent transforming growth factor beta binding protein 2
MAMDC4 MAM domain containing 4
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP4 microtubule-associated protein 4
MCPH1 microcephalin 1
MED22 mediator complex subunit 22
MIB1 mindbomb E3 ubiquitin protein ligase 1
MMP23A matrix metallopeptidase 23A (pseudogene)
MOB2 MOB kinase activator 2
MOB3B MOB kinase activator 3B
MOXD1 monooxygenase, DBH-like 1
MPZL1 myelin protein zero-like 1
MROH7 maestro heat-like repeat family member 7
MRPL50 mitochondrial ribosomal protein L50
MRVI1 murine retrovirus integration site 1 homolog
MST1R macrophage stimulating 1 receptor
MTA2 metastasis associated 1 family, member 2
MYBPC2 myosin binding protein C, fast type
MYEOV myeloma overexpressed
MYO3A myosin IIIA
NALCN sodium leak channel, non selective
NAP1L4 nucleosome assembly protein 1-like 4
NBN nibrin
NBPF3 neuroblastoma breakpoint family, member 3
NCF4 neutrophil cytosolic factor 4, 40kDa
NCOR1 nuclear receptor corepressor 1
NCR1 natural cytotoxicity triggering receptor 1
NFE2L3 nuclear factor, erythroid 2-like 3
NFIB nuclear factor I/B
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOL8 nucleolar protein 8
NPB neuropeptide B
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NT5DC1 5'-nucleotidase domain containing 1
NUP160 nucleoporin 160kDa
NUP188 nucleoporin 188kDa
NUP214 nucleoporin 214kDa
NUP98 nucleoporin 98kDa
NWD1 NACHT and WD repeat domain containing 1
ODF2 outer dense fiber of sperm tails 2
OGFRL1 opioid growth factor receptor-like 1
OLFM1 olfactomedin 1
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1
OR6M1 olfactory receptor, family 6, subfamily M, member 1
ORAOV1 oral cancer overexpressed 1
OTOP1 otopetrin 1
OXER1 oxoeicosanoid (OXE) receptor 1
PACS1 phosphofurin acidic cluster sorting protein 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAPLN papilin, proteoglycan-like sulfated glycoprotein
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PARD3B par-3 family cell polarity regulator beta
PCDHAC1 protocadherin alpha subfamily C, 1
PCM1 pericentriolar material 1
PDE4DIP phosphodiesterase 4D interacting protein
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDS5B PDS5 cohesin associated factor B
PIAS3 protein inhibitor of activated STAT, 3
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIWIL4 piwi-like RNA-mediated gene silencing 4
PKDCC protein kinase domain containing, cytoplasmic
PKP2 plakophilin 2
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCB4 phospholipase C, beta 4
PLD2 phospholipase D2
PLXNA4 plexin A4
PODXL podocalyxin-like
PPBPP2 pro-platelet basic protein pseudogene 2
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRAMEF16 PRAME family member 16
PRELP proline/arginine-rich end leucine-rich repeat protein
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PROX2 prospero homeobox 2
PRR5L proline rich 5 like
PRRC2C proline-rich coiled-coil 2C
PRRX1 paired related homeobox 1
PRSS36 protease, serine, 36
PTBP3 polypyrimidine tract binding protein 3
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAB14 RAB14, member RAS oncogene family
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RABGAP1 RAB GTPase activating protein 1
RAET1K retinoic acid early transcript 1K pseudogene
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RANBP17 RAN binding protein 17
RASD2 RASD family, member 2
RASEF RAS and EF-hand domain containing
RBBP9 retinoblastoma binding protein 9
RCL1 RNA terminal phosphate cyclase-like 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RHBDL3 rhomboid, veinlet-like 3 (Drosophila)
RNF150 ring finger protein 150
RNF165 ring finger protein 165
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase
RTN4RL1 reticulon 4 receptor-like 1
RTP3 receptor (chemosensory) transporter protein 3
RXFP4 relaxin/insulin-like family peptide receptor 4
RYR3 ryanodine receptor 3
S100B S100 calcium binding protein B
SCARA3 scavenger receptor class A, member 3
SCYL3 SCY1-like 3 (S. cerevisiae)
SEPT8 septin 8
SETX senataxin
SFRP4 secreted frizzled-related protein 4
SGK223 homolog of rat pragma of Rnd2
SH2B3 SH2B adaptor protein 3
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SHB Src homology 2 domain containing adaptor protein B
SHISA2 shisa family member 2
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene)
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLFN12L schlafen family member 12-like
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMC2 structural maintenance of chromosomes 2
SNORA16B small nucleolar RNA, H/ACA box 16B
SNORA41 small nucleolar RNA, H/ACA box 41
SNORA45B small nucleolar RNA, H/ACA box 45B
SNX16 sorting nexin 16
SOX8 SRY (sex determining region Y)-box 8
SPANXN3 SPANX family, member N3
SPATA19 spermatogenesis associated 19
SPATA32 spermatogenesis associated 32
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPTBN2 spectrin, beta, non-erythrocytic 2
SSC5D scavenger receptor cysteine rich family, 5 domains
SSRP1 structure specific recognition protein 1
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
STAR steroidogenic acute regulatory protein
STEAP3 STEAP family member 3, metalloreductase
SURF6 surfeit 6
SUSD4 sushi domain containing 4
SYCP3 synaptonemal complex protein 3
SYK spleen tyrosine kinase
SYNDIG1 synapse differentiation inducing 1
SYNPO2 synaptopodin 2
SYTL3 synaptotagmin-like 3
TAL2 T-cell acute lymphocytic leukemia 2
TASP1 taspase, threonine aspartase, 1
TBC1D3P2 TBC1 domain family, member 3 pseudogene 2
TDRP testis development related protein
TENM4 teneurin transmembrane protein 4
TET2 tet methylcytosine dioxygenase 2
THBS2 thrombospondin 2
TLR5 toll-like receptor 5
TMEM130 transmembrane protein 130
TMEM200A transmembrane protein 200A
TMEM200C transmembrane protein 200C
TMEM8C transmembrane protein 8C
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF19 tumor necrosis factor receptor superfamily, member 19
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TP53I11 tumor protein p53 inducible protein 11
TP53TG5 TP53 target 5
TPR translocated promoter region, nuclear basket protein
TRAF1 TNF receptor-associated factor 1
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRIB2 tribbles pseudokinase 2
TRIM14 tripartite motif containing 14
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TSC2 tuberous sclerosis 2
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
TTF1 transcription termination factor, RNA polymerase I
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
TVP23C trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
TYRP1 tyrosinase-related protein 1
UBXN2B UBX domain protein 2B
UEVLD UEV and lactate/malate dehyrogenase domains
UNC5B unc-5 homolog B (C. elegans)
USP20 ubiquitin specific peptidase 20
VASH2 vasohibin 2
VAV2 vav 2 guanine nucleotide exchange factor
VCAN versican
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
VRK2 vaccinia related kinase 2
VSTM4 V-set and transmembrane domain containing 4
WBSCR17 Williams-Beuren syndrome chromosome region 17
WNK2 WNK lysine deficient protein kinase 2
WNT10B wingless-type MMTV integration site family, member 10B
WNT5B wingless-type MMTV integration site family, member 5B
WRN Werner syndrome, RecQ helicase-like
WSCD1 WSC domain containing 1
XYLT1 xylosyltransferase I
ZBTB46 zinc finger and BTB domain containing 46
ZFP91 ZFP91 zinc finger protein
ZHX2 zinc fingers and homeoboxes 2
ZNF137P zinc finger protein 137, pseudogene
ZNF407 zinc finger protein 407
ZNF418 zinc finger protein 418
ZNF462 zinc finger protein 462
ZNF827 zinc finger protein 827
ZSCAN5A zinc finger and SCAN domain containing 5A