Lung squamous cell carcinoma_LUSC_TCGA-34-5236-01A-21R-1820-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

346 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-34-5236-01A-21R-1820-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A1BG-AS1 A1BG antisense RNA 1
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ABHD15 abhydrolase domain containing 15
ACTA2 actin, alpha 2, smooth muscle, aorta
ADD2 adducin 2 (beta)
ADGRL1 adhesion G protein-coupled receptor L1
ADRA2C adrenoceptor alpha 2C
AIDA axin interactor, dorsalization associated
AKAP8 A kinase (PRKA) anchor protein 8
AKAP8L A kinase (PRKA) anchor protein 8-like
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALOXE3 arachidonate lipoxygenase 3
ANTXR1 anthrax toxin receptor 1
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ARHGAP28 Rho GTPase activating protein 28
ARSI arylsulfatase family, member I
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
ASB10 ankyrin repeat and SOCS box containing 10
ATOX1 antioxidant 1 copper chaperone
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BMP8A bone morphogenetic protein 8a
BMP8B bone morphogenetic protein 8b
BPGM 2,3-bisphosphoglycerate mutase
BRD4 bromodomain containing 4
C18ORF21 chromosome 18 open reading frame 21
C1ORF100 chromosome 1 open reading frame 100
C1ORF216 chromosome 1 open reading frame 216
C1ORF68 chromosome 1 open reading frame 68
C1QTNF3 C1q and tumor necrosis factor related protein 3
C20ORF195 chromosome 20 open reading frame 195
C2ORF27A chromosome 2 open reading frame 27A
C6ORF223 chromosome 6 open reading frame 223
C7ORF26 chromosome 7 open reading frame 26
C7ORF49 chromosome 7 open reading frame 49
CALD1 caldesmon 1
CAMTA2 calmodulin binding transcription activator 2
CARD10 caspase recruitment domain family, member 10
CC2D1A coiled-coil and C2 domain containing 1A
CCDC184 coiled-coil domain containing 184
CCIN calicin
CCL11 chemokine (C-C motif) ligand 11
CCL24 chemokine (C-C motif) ligand 24
CCNA1 cyclin A1
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD1B CD1b molecule
CD207 CD207 molecule, langerin
CD248 CD248 molecule, endosialin
CEP170P1 centrosomal protein 170kDa pseudogene 1
CEP295 centrosomal protein 295kDa
CERCAM cerebral endothelial cell adhesion molecule
CES5A carboxylesterase 5A
CGB2 chorionic gonadotropin, beta polypeptide 2
CHN1 chimerin 1
CKMT1A creatine kinase, mitochondrial 1A
CLEC11A C-type lectin domain family 11, member A
CLEC5A C-type lectin domain family 5, member A
CNOT4 CCR4-NOT transcription complex, subunit 4
CNPY4 canopy FGF signaling regulator 4
CNTN3 contactin 3 (plasmacytoma associated)
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COL12A1 collagen, type XII, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
COL6A3 collagen, type VI, alpha 3
CT45A1 cancer/testis antigen family 45, member A1
CT45A3 cancer/testis antigen family 45, member A3
CT55 cancer/testis antigen 55
CTCFL CCCTC-binding factor (zinc finger protein)-like
CTHRC1 collagen triple helix repeat containing 1
CTIF CBP80/20-dependent translation initiation factor
CTNS cystinosin, lysosomal cystine transporter
CTSK cathepsin K
CWC15 CWC15 spliceosome-associated protein
CYB561D1 cytochrome b561 family, member D1
DACT3 dishevelled-binding antagonist of beta-catenin 3
DCAF15 DDB1 and CUL4 associated factor 15
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DEFB132 defensin, beta 132
DIO2 deiodinase, iodothyronine, type II
DIRC1 disrupted in renal carcinoma 1
DKFZP434J0226 uncharacterized LOC93429
DNAAF5 dynein, axonemal, assembly factor 5
DPEP3 dipeptidase 3
DPH3P1 diphthamide biosynthesis 3 pseudogene 1
DPT dermatopontin
DUSP18 dual specificity phosphatase 18
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
EIF3B eukaryotic translation initiation factor 3, subunit B
ELOVL1 ELOVL fatty acid elongase 1
ELP2 elongator acetyltransferase complex subunit 2
EPHA1 EPH receptor A1
F12 coagulation factor XII (Hageman factor)
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
FAM20C family with sequence similarity 20, member C
FAM25A family with sequence similarity 25, member A
FAM72A family with sequence similarity 72, member A
FBLN2 fibulin 2
FOXD3 forkhead box D3
FTSJ2 FtsJ RNA methyltransferase homolog 2 (E. coli)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAGE12D G antigen 12D
GAGE12F G antigen 12F
GAGE2D G antigen 2D
GAGE4 G antigen 4
GALNS galactosamine (N-acetyl)-6-sulfatase
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GAS2L1 growth arrest-specific 2 like 1
GAST gastrin
GATSL2 GATS protein-like 2
GCC1 GRIP and coiled-coil domain containing 1
GCK glucokinase (hexokinase 4)
GEMIN4 gem (nuclear organelle) associated protein 4
GGACT gamma-glutamylamine cyclotransferase
GJA3 gap junction protein, alpha 3, 46kDa
GJB2 gap junction protein, beta 2, 26kDa
GLT8D2 glycosyltransferase 8 domain containing 2
GML glycosylphosphatidylinositol anchored molecule like
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNAS-AS1 GNAS antisense RNA 1
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPRIN1 G protein regulated inducer of neurite outgrowth 1
GREM1 gremlin 1, DAN family BMP antagonist
GTF2A1L general transcription factor IIA, 1-like
HARS2 histidyl-tRNA synthetase 2, mitochondrial
HEATR1 HEAT repeat containing 1
HMX2 H6 family homeobox 2
HOXA7 homeobox A7
HSPA12A heat shock 70kDa protein 12A
HTRA1 HtrA serine peptidase 1
HTRA3 HtrA serine peptidase 3
IBSP integrin-binding sialoprotein
IER3IP1 immediate early response 3 interacting protein 1
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4
IGFL2 IGF-like family member 2
IGFL4 IGF-like family member 4
IL36RN interleukin 36 receptor antagonist
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INO80C INO80 complex subunit C
IPO13 importin 13
IQCF2 IQ motif containing F2
ISLR immunoglobulin superfamily containing leucine-rich repeat
ISM1 isthmin 1, angiogenesis inhibitor
ITGA11 integrin, alpha 11
ITGB5 integrin, beta 5
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KIAA0226 KIAA0226
KIF1C kinesin family member 1C
L3MBTL2 l(3)mbt-like 2 (Drosophila)
LAMC2 laminin, gamma 2
LCE1F late cornified envelope 1F
LCE3E late cornified envelope 3E
LCN1 lipocalin 1
LGALS1 lectin, galactoside-binding, soluble, 1
LIMK1 LIM domain kinase 1
LINC00152 long intergenic non-protein coding RNA 152
LINC00520 long intergenic non-protein coding RNA 520
LIPG lipase, endothelial
LIPM lipase, family member M
LMLN leishmanolysin-like (metallopeptidase M8 family)
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC15 leucine rich repeat containing 15
LRRC59 leucine rich repeat containing 59
LRWD1 leucine-rich repeats and WD repeat domain containing 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAGEB2 melanoma antigen family B2
MAGEC1 melanoma antigen family C1
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MED17 mediator complex subunit 17
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MIR99AHG mir-99a-let-7c cluster host gene
MLNR motilin receptor
MMP1 matrix metallopeptidase 1
MMP11 matrix metallopeptidase 11
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MORC1 MORC family CW-type zinc finger 1
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSC musculin
MTMR2 myotubularin related protein 2
MXRA8 matrix-remodelling associated 8
MYBBP1A MYB binding protein (P160) 1a
MYH16 myosin, heavy chain 16 pseudogene
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit
NBL1 neuroblastoma 1, DAN family BMP antagonist
NBPF3 neuroblastoma breakpoint family, member 3
NDP Norrie disease (pseudoglioma)
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NES nestin
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1
NEU2 sialidase 2 (cytosolic sialidase)
NIPAL4 NIPA-like domain containing 4
NKD2 naked cuticle homolog 2 (Drosophila)
NMB neuromedin B
NOTCH3 notch 3
NRP2 neuropilin 2
OR2C3 olfactory receptor, family 2, subfamily C, member 3
OR2T8 olfactory receptor, family 2, subfamily T, member 8
OR2W3 olfactory receptor, family 2, subfamily W, member 3
ORAI2 ORAI calcium release-activated calcium modulator 2
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PANX1 pannexin 1
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PELP1 proline, glutamate and leucine rich protein 1
PFN1 profilin 1
PGLYRP2 peptidoglycan recognition protein 2
PHF14 PHD finger protein 14
PHF7 PHD finger protein 7
PI3 peptidase inhibitor 3, skin-derived
PITPNA phosphatidylinositol transfer protein, alpha
PLCXD2 phosphatidylinositol-specific phospholipase C, X domain containing 2
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
PLEKHA8P1 pleckstrin homology domain containing, family A member 8 pseudogene 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PNPLA3 patatin-like phospholipase domain containing 3
PNPLA5 patatin-like phospholipase domain containing 5
PODNL1 podocan-like 1
POM121 POM121 transmembrane nucleoporin
POM121C POM121 transmembrane nucleoporin C
POMZP3 POM121 and ZP3 fusion
POPDC3 popeye domain containing 3
PPAPDC1A phosphatidic acid phosphatase type 2 domain containing 1A
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRSS50 protease, serine, 50
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RADIL Ras association and DIL domains
RBAK RB-associated KRAB zinc finger
RBBP5 retinoblastoma binding protein 5
REP15 RAB15 effector protein
RHOXF1 Rhox homeobox family, member 1
RNF167 ring finger protein 167
RNF187 ring finger protein 187
RNF216P1 ring finger protein 216 pseudogene 1
RNF24 ring finger protein 24
RPL23AP82 ribosomal protein L23a pseudogene 82
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
RPSAP52 ribosomal protein SA pseudogene 52
SAGE1 sarcoma antigen 1
SAMD1 sterile alpha motif domain containing 1
SCN9A sodium channel, voltage gated, type IX alpha subunit
SCT secretin
SDAD1 SDA1 domain containing 1
SDK1 sidekick cell adhesion molecule 1
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SEPT8 septin 8
SERTAD4-AS1 SERTAD4 antisense RNA 1
SFRP4 secreted frizzled-related protein 4
SH2D5 SH2 domain containing 5
SH3BP5L SH3-binding domain protein 5-like
SH3PXD2B SH3 and PX domains 2B
SHH sonic hedgehog
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC41A1 solute carrier family 41 (magnesium transporter), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMAD2 SMAD family member 2
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNORA14A small nucleolar RNA, H/ACA box 14A
SNORA84 small nucleolar RNA, H/ACA box 84
SPDYE3 speedy/RINGO cell cycle regulator family member E3
SRRM3 serine/arginine repetitive matrix 3
SRSF8 serine/arginine-rich splicing factor 8
SULF1 sulfatase 1
SUN5 Sad1 and UNC84 domain containing 5
SUSD1 sushi domain containing 1
SZT2 seizure threshold 2 homolog (mouse)
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TBX20 T-box 20
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THBS2 thrombospondin 2
THOC5 THO complex 5
THY1 Thy-1 cell surface antigen
TIGD6 tigger transposable element derived 6
TIMP2 TIMP metallopeptidase inhibitor 2
TLL2 tolloid-like 2
TM4SF19 transmembrane 4 L six family member 19
TM6SF2 transmembrane 6 superfamily member 2
TMED7-TICAM2 TMED7-TICAM2 readthrough
TMEM255B transmembrane protein 255B
TMEM45A transmembrane protein 45A
TMEM81 transmembrane protein 81
TNNI1 troponin I type 1 (skeletal, slow)
TNPO3 transportin 3
TPGS2 tubulin polyglutamylase complex subunit 2
TPM2 tropomyosin 2 (beta)
TPRG1 tumor protein p63 regulated 1
TRIM58 tripartite motif containing 58
TRIM7 tripartite motif containing 7
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC26 tetratricopeptide repeat domain 26
TTLL13P tubulin tyrosine ligase-like family member 13, pseudogene
TUBB6 tubulin, beta 6 class V
TYRO3 TYRO3 protein tyrosine kinase
UBE2DNL ubiquitin-conjugating enzyme E2D N-terminal like (pseudogene)
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UNC93A unc-93 homolog A (C. elegans)
UPP1 uridine phosphorylase 1
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP42 ubiquitin specific peptidase 42
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
WDR53 WD repeat domain 53
WFDC1 WAP four-disulfide core domain 1
WIZ widely interspaced zinc finger motifs
WNT2 wingless-type MMTV integration site family member 2
WNT7A wingless-type MMTV integration site family, member 7A
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZBED2 zinc finger, BED-type containing 2
ZBTB7C zinc finger and BTB domain containing 7C
ZBTB9 zinc finger and BTB domain containing 9
ZC3H11A zinc finger CCCH-type containing 11A
ZC3HC1 zinc finger, C3HC-type containing 1
ZDHHC4 zinc finger, DHHC-type containing 4
ZFP42 ZFP42 zinc finger protein
ZFPM1 zinc finger protein, FOG family member 1
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF24 zinc finger protein 24
ZNF271P zinc finger protein 271, pseudogene
ZNF280A zinc finger protein 280A
ZNF396 zinc finger protein 396
ZNF397 zinc finger protein 397
ZNF398 zinc finger protein 398
ZNF454 zinc finger protein 454
ZNF469 zinc finger protein 469
ZNF672 zinc finger protein 672
ZNF786 zinc finger protein 786
ZNF815P zinc finger protein 815, pseudogene
ZSCAN21 zinc finger and SCAN domain containing 21

low expression

Symbol Name
PPP1R7 protein phosphatase 1, regulatory subunit 7