Lung squamous cell carcinoma_LUSC_TCGA-33-A5GW-01A-11R-A27Q-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

406 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-33-A5GW-01A-11R-A27Q-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A2ML1 alpha-2-macroglobulin-like 1
AADAC arylacetamide deacetylase
AAMP angio-associated, migratory cell protein
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABHD2 abhydrolase domain containing 2
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ABRACL ABRA C-terminal like
ACE2 angiotensin I converting enzyme 2
ACKR3 atypical chemokine receptor 3
ACO2 aconitase 2, mitochondrial
ACOT13 acyl-CoA thioesterase 13
ACTL10 actin-like 10
ACYP2 acylphosphatase 2, muscle type
ADGRF1 adhesion G protein-coupled receptor F1
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AES amino-terminal enhancer of split
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AKT1S1 AKT1 substrate 1 (proline-rich)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase
AMN amnion associated transmembrane protein
ANKRD13C ankyrin repeat domain 13C
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6
ANP32C acidic (leucine-rich) nuclear phosphoprotein 32 family, member C
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
APOL1 apolipoprotein L, 1
APOL2 apolipoprotein L, 2
APRT adenine phosphoribosyltransferase
ARFIP2 ADP-ribosylation factor interacting protein 2
ARHGAP32 Rho GTPase activating protein 32
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
ASPH aspartate beta-hydroxylase
ATG4D autophagy related 4D, cysteine peptidase
ATP10B ATPase, class V, type 10B
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
ATP5EP2 ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
ATP5L2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
AXDND1 axonemal dynein light chain domain containing 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BCL6 B-cell CLL/lymphoma 6
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BID BH3 interacting domain death agonist
BMP7 bone morphogenetic protein 7
BMPR1B bone morphogenetic protein receptor, type IB
C10ORF99 chromosome 10 open reading frame 99
C1ORF177 chromosome 1 open reading frame 177
C20ORF24 chromosome 20 open reading frame 24
C21ORF33 chromosome 21 open reading frame 33
C4ORF17 chromosome 4 open reading frame 17
C6ORF136 chromosome 6 open reading frame 136
C8G complement component 8, gamma polypeptide
CA12 carbonic anhydrase XII
CAGE1 cancer antigen 1
CAPNS2 calpain, small subunit 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBR1 carbonyl reductase 1
CBR3 carbonyl reductase 3
CCDC80 coiled-coil domain containing 80
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDK9 cyclin-dependent kinase 9
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CES1 carboxylesterase 1
CES1P1 carboxylesterase 1 pseudogene 1
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10
CHID1 chitinase domain containing 1
CHP2 calcineurin-like EF-hand protein 2
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CIRBP-AS1 CIRBP antisense RNA 1
CLCN1 chloride channel, voltage-sensitive 1
CLDN8 claudin 8
CLINT1 clathrin interactor 1
CLU clusterin
CMIP c-Maf inducing protein
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
CNGA1 cyclic nucleotide gated channel alpha 1
CNOT2 CCR4-NOT transcription complex, subunit 2
COLCA1 colorectal cancer associated 1
COPG1 coatomer protein complex, subunit gamma 1
COQ4 coenzyme Q4
COQ9 coenzyme Q9
CORO2A coronin, actin binding protein, 2A
COX4I1 cytochrome c oxidase subunit IV isoform 1
COX5A cytochrome c oxidase subunit Va
COX5B cytochrome c oxidase subunit Vb
COX6C cytochrome c oxidase subunit VIc
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRAT carnitine O-acetyltransferase
CSTA cystatin A (stefin A)
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
CTR9 CTR9, Paf1/RNA polymerase II complex component
CTSC cathepsin C
CUL3 cullin 3
CXCL17 chemokine (C-X-C motif) ligand 17
CYCS cytochrome c, somatic
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1
DAB2IP DAB2 interacting protein
DAZAP2 DAZ associated protein 2
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DEXI Dexi homolog (mouse)
DGCR6 DiGeorge syndrome critical region gene 6
DHFRL1 dihydrofolate reductase-like 1
DNAJC25 DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
DOLK dolichol kinase
DUOX2 dual oxidase 2
DYNLL2 dynein, light chain, LC8-type 2
EEA1 early endosome antigen 1
EI24 etoposide induced 2.4
EIF3J eukaryotic translation initiation factor 3, subunit J
ELMO3 engulfment and cell motility 3
EMC8 ER membrane protein complex subunit 8
EPHA1 EPH receptor A1
EPHA4 EPH receptor A4
EPHB3 EPH receptor B3
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPHX3 epoxide hydrolase 3
EPN3 epsin 3
ERMP1 endoplasmic reticulum metallopeptidase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ERP44 endoplasmic reticulum protein 44
ESR1 estrogen receptor 1
ESRRA estrogen-related receptor alpha
EVA1C eva-1 homolog C (C. elegans)
EVPL envoplakin
EXT1 exostosin glycosyltransferase 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP5P3 fatty acid binding protein 5 pseudogene 3
FADS2 fatty acid desaturase 2
FAHD1 fumarylacetoacetate hydrolase domain containing 1
FAM114A1 family with sequence similarity 114, member A1
FAM120B family with sequence similarity 120B
FAM181B family with sequence similarity 181, member B
FAM192A family with sequence similarity 192, member A
FAM3D family with sequence similarity 3, member D
FAM47A family with sequence similarity 47, member A
FAM83A family with sequence similarity 83, member A
FEM1A fem-1 homolog a (C. elegans)
FGFBP1 fibroblast growth factor binding protein 1
FGFBP2 fibroblast growth factor binding protein 2
FMO4 flavin containing monooxygenase 4
FMO6P flavin containing monooxygenase 6 pseudogene
FUT2 fucosyltransferase 2 (secretor status included)
G6PC3 glucose 6 phosphatase, catalytic, 3
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GAL3ST2 galactose-3-O-sulfotransferase 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GAN gigaxonin
GAR1 GAR1 ribonucleoprotein
GCLC glutamate-cysteine ligase, catalytic subunit
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GGNBP2 gametogenetin binding protein 2
GJA9 gap junction protein, alpha 9, 59kDa
GLUL glutamate-ammonia ligase
GMDS GDP-mannose 4,6-dehydratase
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GOLGB1 golgin B1
GORASP2 golgi reassembly stacking protein 2, 55kDa
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPR137 G protein-coupled receptor 137
GPR158 G protein-coupled receptor 158
GPRC5C G protein-coupled receptor, class C, group 5, member C
GRHL2 grainyhead-like 2 (Drosophila)
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
GSTA1 glutathione S-transferase alpha 1
GSTM2P1 glutathione S-transferase mu 2 (muscle) pseudogene 1
GSTP1 glutathione S-transferase pi 1
GTF2A2 general transcription factor IIA, 2, 12kDa
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HHLA3 HERV-H LTR-associating 3
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HSPB1 heat shock 27kDa protein 1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HYPK huntingtin interacting protein K
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDUA iduronidase, alpha-L-
IGFBP3 insulin-like growth factor binding protein 3
IKZF2 IKAROS family zinc finger 2 (Helios)
IL20RA interleukin 20 receptor, alpha
ILDR1 immunoglobulin-like domain containing receptor 1
IPO13 importin 13
ITFG3 integrin alpha FG-GAP repeat containing 3
IVD isovaleryl-CoA dehydrogenase
IVL involucrin
JUP junction plakoglobin
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIAA1522 KIAA1522
KLF3 Kruppel-like factor 3 (basic)
KRT13 keratin 13, type I
KRT15 keratin 15, type I
KRT4 keratin 4, type II
KRT5 keratin 5, type II
LCMT2 leucine carboxyl methyltransferase 2
LENG9 leukocyte receptor cluster (LRC) member 9
LHX6 LIM homeobox 6
LINC00474 long intergenic non-protein coding RNA 474
LINC01548 long intergenic non-protein coding RNA 1548
LOC285593 uncharacterized LOC285593
LOC285629 uncharacterized LOC285629
LOC93622 Morf4 family associated protein 1-like 1 pseudogene
LRG1 leucine-rich alpha-2-glycoprotein 1
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC40 leucine rich repeat containing 40
LRRC41 leucine rich repeat containing 41
LYNX1 Ly6/neurotoxin 1
LYPD3 LY6/PLAUR domain containing 3
MAB21L3 mab-21-like 3 (C. elegans)
MAOA monoamine oxidase A
MAPK10 mitogen-activated protein kinase 10
MARC1 mitochondrial amidoxime reducing component 1
MARVELD3 MARVEL domain containing 3
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1
MECOM MDS1 and EVI1 complex locus
METAP1 methionyl aminopeptidase 1
MFSD5 major facilitator superfamily domain containing 5
MOB2 MOB kinase activator 2
MPZL2 myelin protein zero-like 2
MREG melanoregulin
MRFAP1 Morf4 family associated protein 1
MRFAP1L1 Morf4 family associated protein 1-like 1
MRPS18C mitochondrial ribosomal protein S18C
MUC20 mucin 20, cell surface associated
MUC4 mucin 4, cell surface associated
MYL5 myosin, light chain 5, regulatory
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NACA2 nascent polypeptide-associated complex alpha subunit 2
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NAIF1 nuclear apoptosis inducing factor 1
NAMPT nicotinamide phosphoribosyltransferase
NANS N-acetylneuraminic acid synthase
NAP1L4 nucleosome assembly protein 1-like 4
NCDN neurochondrin
NCL nucleolin
NCOA3 nuclear receptor coactivator 3
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)
NFE2L2 nuclear factor, erythroid 2-like 2
NOMO2 NODAL modulator 2
NOTCH3 notch 3
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRG4 neuregulin 4
NUCB2 nucleobindin 2
OCM2 oncomodulin 2
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
OR9A4 olfactory receptor, family 9, subfamily A, member 4
OSBPL2 oxysterol binding protein-like 2
OSGIN1 oxidative stress induced growth inhibitor 1
PCNXL3 pecanex-like 3 (Drosophila)
PDGFD platelet derived growth factor D
PGD phosphogluconate dehydrogenase
PGLYRP3 peptidoglycan recognition protein 3
PGM2 phosphoglucomutase 2
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIGP phosphatidylinositol glycan anchor biosynthesis, class P
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y
PLBD1 phospholipase B domain containing 1
PMFBP1 polyamine modulated factor 1 binding protein 1
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
POR P450 (cytochrome) oxidoreductase
PPA2 pyrophosphatase (inorganic) 2
PPAP2C phosphatidic acid phosphatase type 2C
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2
PPIC peptidylprolyl isomerase C (cyclophilin C)
PPL periplakin
PRCP prolylcarboxypeptidase (angiotensinase C)
PRDX1 peroxiredoxin 1
PRODH proline dehydrogenase (oxidase) 1
PROM2 prominin 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTGR1 prostaglandin reductase 1
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAB10 RAB10, member RAS oncogene family
RAB21 RAB21, member RAS oncogene family
RAB38 RAB38, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RARG retinoic acid receptor, gamma
RHBDL2 rhomboid, veinlet-like 2 (Drosophila)
RHOV ras homolog family member V
RIPK4 receptor-interacting serine-threonine kinase 4
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RNF135 ring finger protein 135
RNF141 ring finger protein 141
RNF217-AS1 RNF217 antisense RNA 1 (head to head)
RPL29P2 ribosomal protein L29 pseudogene 2
RRBP1 ribosome binding protein 1
RTN3 reticulon 3
RXRA retinoid X receptor, alpha
S1PR5 sphingosine-1-phosphate receptor 5
SAT1 spermidine/spermine N1-acetyltransferase 1
SCAMP2 secretory carrier membrane protein 2
SCARNA15 small Cajal body-specific RNA 15
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SDC1 syndecan 1
SEC61B Sec61 beta subunit
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SHBG sex hormone-binding globulin
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC22A18 solute carrier family 22, member 18
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC39A11 solute carrier family 39, member 11
SLC51A solute carrier family 51, alpha subunit
SLURP1 secreted LY6/PLAUR domain containing 1
SMAD3 SMAD family member 3
SNORA5C small nucleolar RNA, H/ACA box 5C
SOD1 superoxide dismutase 1, soluble
SORD sorbitol dehydrogenase
SPAG16 sperm associated antigen 16
SPATA2 spermatogenesis associated 2
SPDYE4 speedy/RINGO cell cycle regulator family member E4
SPINK8 serine peptidase inhibitor, Kazal type 8 (putative)
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPP1 secreted phosphoprotein 1
SREBF1 sterol regulatory element binding transcription factor 1
SRPR signal recognition particle receptor (docking protein)
SRPRB signal recognition particle receptor, B subunit
SRSF11 serine/arginine-rich splicing factor 11
STC2 stanniocalcin 2
STIM1 stromal interaction molecule 1
STIM2 stromal interaction molecule 2
STK38 serine/threonine kinase 38
STX19 syntaxin 19
SUSD4 sushi domain containing 4
SYK spleen tyrosine kinase
TALDO1 transaldolase 1
TBC1D15 TBC1 domain family, member 15
TBC1D2 TBC1 domain family, member 2
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
TECR trans-2,3-enoyl-CoA reductase
TEF thyrotrophic embryonic factor
TFG TRK-fused gene
TGM5 transglutaminase 5
THAP2 THAP domain containing, apoptosis associated protein 2
TJP3 tight junction protein 3
TKFC triokinase/FMN cyclase
TMC4 transmembrane channel-like 4
TMEM129 transmembrane protein 129, E3 ubiquitin protein ligase
TMEM132A transmembrane protein 132A
TMEM19 transmembrane protein 19
TMEM33 transmembrane protein 33
TMEM37 transmembrane protein 37
TMEM41B transmembrane protein 41B
TMEM9B TMEM9 domain family, member B
TMPRSS4 transmembrane protease, serine 4
TOLLIP toll interacting protein
TP53I3 tumor protein p53 inducible protein 3
TRIM29 tripartite motif containing 29
TRIM7 tripartite motif containing 7
TSKU tsukushi, small leucine rich proteoglycan
TSPAN7 tetraspanin 7
TSSC4 tumor suppressing subtransferable candidate 4
TUBBP5 tubulin, beta pseudogene 5
TXN thioredoxin
UBE2K ubiquitin-conjugating enzyme E2K
UBQLN2 ubiquilin 2
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UPK1B uroplakin 1B
UQCRB ubiquinol-cytochrome c reductase binding protein
UQCRH ubiquinol-cytochrome c reductase hinge protein
UQCRHL ubiquinol-cytochrome c reductase hinge protein-like
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae)
WFDC2 WAP four-disulfide core domain 2
WNT4 wingless-type MMTV integration site family, member 4
WNT5A wingless-type MMTV integration site family, member 5A
WNT7B wingless-type MMTV integration site family, member 7B
YBEY ybeY metallopeptidase (putative)
ZBTB7A zinc finger and BTB domain containing 7A
ZBTB8OS zinc finger and BTB domain containing 8 opposite strand
ZDHHC13 zinc finger, DHHC-type containing 13
ZDHHC24 zinc finger, DHHC-type containing 24
ZDHHC5 zinc finger, DHHC-type containing 5
ZNF229 zinc finger protein 229
ZNF480 zinc finger protein 480
ZNF91 zinc finger protein 91

low expression

Symbol Name
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
KIAA1033 KIAA1033
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
PTEN phosphatase and tensin homolog
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional)
UHRF1BP1L UHRF1 binding protein 1-like