Lung squamous cell carcinoma_LUSC_TCGA-33-A4WN-01A-11R-A262-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

412 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-33-A4WN-01A-11R-A262-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A2ML1 alpha-2-macroglobulin-like 1
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABLIM1 actin binding LIM protein 1
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ADAM15 ADAM metallopeptidase domain 15
ADAM9 ADAM metallopeptidase domain 9
ADGRF1 adhesion G protein-coupled receptor F1
ADGRF2 adhesion G protein-coupled receptor F2
AFF1 AF4/FMR2 family, member 1
AGAP11 ankyrin repeat and GTPase domain Arf GTPase activating protein 11
AIM1L absent in melanoma 1-like
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALMS1 Alstrom syndrome protein 1
ALOXE3 arachidonate lipoxygenase 3
ANXA9 annexin A9
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
APOL1 apolipoprotein L, 1
APOO apolipoprotein O
ARAF A-Raf proto-oncogene, serine/threonine kinase
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ASIC1 acid sensing (proton gated) ion channel 1
ATMIN ATM interactor
ATP10B ATPase, class V, type 10B
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1
ATR ATR serine/threonine kinase
BBX bobby sox homolog (Drosophila)
BCO1 beta-carotene oxygenase 1
BCO2 beta-carotene oxygenase 2
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BIRC6 baculoviral IAP repeat containing 6
BMP7 bone morphogenetic protein 7
BNIPL BCL2/adenovirus E1B 19kD interacting protein like
C10ORF90 chromosome 10 open reading frame 90
C10ORF99 chromosome 10 open reading frame 99
C15ORF59 chromosome 15 open reading frame 59
C16ORF74 chromosome 16 open reading frame 74
C1ORF106 chromosome 1 open reading frame 106
C1ORF61 chromosome 1 open reading frame 61
C5ORF52 chromosome 5 open reading frame 52
CA5BP1 carbonic anhydrase VB pseudogene 1
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
CAPN1 calpain 1, (mu/I) large subunit
CAPN14 calpain 14
CAPN2 calpain 2, (m/II) large subunit
CARD14 caspase recruitment domain family, member 14
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CC2D1A coiled-coil and C2 domain containing 1A
CCBL2 cysteine conjugate-beta lyase 2
CCDC120 coiled-coil domain containing 120
CCDC22 coiled-coil domain containing 22
CCR3 chemokine (C-C motif) receptor 3
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDK16 cyclin-dependent kinase 16
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CDV3 CDV3 homolog (mouse)
CENPC centromere protein C
CES1 carboxylesterase 1
CFAP47 cilia and flagella associated protein 47
CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLCN5 chloride channel, voltage-sensitive 5
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLUH clustered mitochondria (cluA/CLU1) homolog
CNOT6L CCR4-NOT transcription complex, subunit 6-like
COA6 cytochrome c oxidase assembly factor 6
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
CPEB2 cytoplasmic polyadenylation element binding protein 2
CPOX coproporphyrinogen oxidase
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRYBG3 beta-gamma crystallin domain containing 3
CSTA cystatin A (stefin A)
CTAG2 cancer/testis antigen 2
CUL4B cullin 4B
CXORF23 chromosome X open reading frame 23
CXORF38 chromosome X open reading frame 38
CXORF58 chromosome X open reading frame 58
DAPL1 death associated protein-like 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCAF4L2 DDB1 and CUL4 associated factor 4-like 2
DCAF6 DDB1 and CUL4 associated factor 6
DHRS9 dehydrogenase/reductase (SDR family) member 9
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32
DIRC2 disrupted in renal carcinoma 2
DNAAF5 dynein, axonemal, assembly factor 5
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DSC1 desmocollin 1
DSC2 desmocollin 2
DSG3 desmoglein 3
DUSP21 dual specificity phosphatase 21
DYNLT3 dynein, light chain, Tctex-type 3
EBP emopamil binding protein (sterol isomerase)
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EHD3 EH-domain containing 3
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELK1 ELK1, member of ETS oncogene family
ELL2 elongation factor, RNA polymerase II, 2
EPN3 epsin 3
EPRS glutamyl-prolyl-tRNA synthetase
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
EPS8L1 EPS8-like 1
EPS8L2 EPS8-like 2
ERICH5 glutamate-rich 5
ESRP2 epithelial splicing regulatory protein 2
EVPL envoplakin
EXOC3 exocyst complex component 3
EXOC6B exocyst complex component 6B
FAM102A family with sequence similarity 102, member A
FAM131C family with sequence similarity 131, member C
FAM156A family with sequence similarity 156, member A
FAM84A family with sequence similarity 84, member A
FANCB Fanconi anemia, complementation group B
FBF1 Fas (TNFRSF6) binding factor 1
FDPS farnesyl diphosphate synthase
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF1 fibroblast growth factor 1 (acidic)
FGFR1 fibroblast growth factor receptor 1
FGFR1OP FGFR1 oncogene partner
FH fumarate hydratase
FLJ23867 uncharacterized protein FLJ23867
FNTA farnesyltransferase, CAAX box, alpha
FOXN1 forkhead box N1
FRRS1L ferric-chelate reductase 1-like
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli)
FUNDC1 FUN14 domain containing 1
GALNT4 polypeptide N-acetylgalactosaminyltransferase 4
GBP6 guanylate binding protein family, member 6
GEN1 GEN1 Holliday junction 5' flap endonuclease
GFAP glial fibrillary acidic protein
GFM1 G elongation factor, mitochondrial 1
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GGT6 gamma-glutamyltransferase 6
GID4 GID complex subunit 4
GLUD2 glutamate dehydrogenase 2
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GOLGA7 golgin A7
GOLGB1 golgin B1
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPKOW G patch domain and KOW motifs
GPR173 G protein-coupled receptor 173
GPRC5C G protein-coupled receptor, class C, group 5, member C
GPRC5D G protein-coupled receptor, class C, group 5, member D
GRAMD1C GRAM domain containing 1C
GREB1 growth regulation by estrogen in breast cancer 1
GRHL3 grainyhead-like 3 (Drosophila)
GRIPAP1 GRIP1 associated protein 1
GRSF1 G-rich RNA sequence binding factor 1
GSK3B glycogen synthase kinase 3 beta
GTPBP8 GTP-binding protein 8 (putative)
GULP1 GULP, engulfment adaptor PTB domain containing 1
H1FX H1 histone family, member X
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HCCS holocytochrome c synthase
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific
HOOK3 hook microtubule-tethering protein 3
HPS3 Hermansky-Pudlak syndrome 3
HPSE heparanase
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
HSPA12A heat shock 70kDa protein 12A
HSPB1 heat shock 27kDa protein 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
IDE insulin-degrading enzyme
IKZF2 IKAROS family zinc finger 2 (Helios)
IQCG IQ motif containing G
IQGAP3 IQ motif containing GTPase activating protein 3
IQSEC2 IQ motif and Sec7 domain 2
IVL involucrin
JADE3 jade family PHD finger 3
JAZF1 JAZF zinc finger 1
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1
KCTD21 potassium channel tetramerization domain containing 21
KDM5C lysine (K)-specific demethylase 5C
KDM6A lysine (K)-specific demethylase 6A
KIAA1211 KIAA1211
KIAA1468 KIAA1468
KIAA1598
KIAA2018 KIAA2018
KLF8 Kruppel-like factor 8
KPNA1 karyopherin alpha 1 (importin alpha 5)
KPNA4 karyopherin alpha 4 (importin alpha 3)
KRT19 keratin 19, type I
KRT77 keratin 77, type II
KRT78 keratin 78, type II
KRTAP4-12 keratin associated protein 4-12
L3MBTL3 l(3)mbt-like 3 (Drosophila)
LAD1 ladinin 1
LGALS9B lectin, galactoside-binding, soluble, 9B
LIN54 lin-54 DREAM MuvB core complex component
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LOC221122 uncharacterized LOC221122
LOC285629 uncharacterized LOC285629
LOC646762 uncharacterized LOC646762
LOX lysyl oxidase
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC58 leucine rich repeat containing 58
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAOA monoamine oxidase A
MAP2 microtubule-associated protein 2
MAPK10 mitogen-activated protein kinase 10
MARVELD3 MARVEL domain containing 3
MBP myelin basic protein
MED13 mediator complex subunit 13
MED14 mediator complex subunit 14
MFN1 mitofusin 1
MID1IP1 MID1 interacting protein 1
MINA MYC induced nuclear antigen
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MKNK1 MAP kinase interacting serine/threonine kinase 1
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MOB1A MOB kinase activator 1A
MOG myelin oligodendrocyte glycoprotein
MOSPD2 motile sperm domain containing 2
MRPL19 mitochondrial ribosomal protein L19
MRPS18C mitochondrial ribosomal protein S18C
MSTO1 misato 1, mitochondrial distribution and morphology regulator
MYO18A myosin XVIIIA
MYO5B myosin VB
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2
NBEAL2 neurobeachin-like 2
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
NLRP2 NLR family, pyrin domain containing 2
NMB neuromedin B
NPEPPS aminopeptidase puromycin sensitive
NPFFR2 neuropeptide FF receptor 2
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NR0B1 nuclear receptor subfamily 0, group B, member 1
NRBP1 nuclear receptor binding protein 1
NUAK2 NUAK family, SNF1-like kinase, 2
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16
NUP88 nucleoporin 88kDa
NXF3 nuclear RNA export factor 3
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1
OLIG2 oligodendrocyte lineage transcription factor 2
OPA1 optic atrophy 1 (autosomal dominant)
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
OR2A14 olfactory receptor, family 2, subfamily A, member 14
OR56A3 olfactory receptor, family 56, subfamily A, member 3
OTUD5 OTU deubiquitinase 5
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PABPC1L2A poly(A) binding protein, cytoplasmic 1-like 2A
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B
PADI6 peptidyl arginine deiminase, type VI
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAQR6 progestin and adipoQ receptor family member VI
PAQR7 progestin and adipoQ receptor family member VII
PAQR8 progestin and adipoQ receptor family member VIII
PC pyruvate carboxylase
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PGLYRP3 peptidoglycan recognition protein 3
PHF8 PHD finger protein 8
PIAS3 protein inhibitor of activated STAT, 3
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIR pirin (iron-binding nuclear protein)
PITPNM3 PITPNM family member 3
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHA7 pleckstrin homology domain containing, family A member 7
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
PLEKHN1 pleckstrin homology domain containing, family N member 1
PNPLA1 patatin-like phospholipase domain containing 1
POF1B premature ovarian failure, 1B
POLQ polymerase (DNA directed), theta
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPIAL4E peptidylprolyl isomerase A (cyclophilin A)-like 4E
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PPP1R3F protein phosphatase 1, regulatory subunit 3F
PRICKLE3 prickle homolog 3 (Drosophila)
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRMT7 protein arginine methyltransferase 7
PROM2 prominin 2
PROSC proline synthetase co-transcribed homolog (bacterial)
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PTGR1 prostaglandin reductase 1
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PVRL4 poliovirus receptor-related 4
RAB10 RAB10, member RAS oncogene family
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB25 RAB25, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBMXL1 RNA binding motif protein, X-linked-like 1
RDH13 retinol dehydrogenase 13 (all-trans/9-cis)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHBDL2 rhomboid, veinlet-like 2 (Drosophila)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF170 ring finger protein 170
RNF39 ring finger protein 39
RNPEP arginyl aminopeptidase (aminopeptidase B)
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPP40 ribonuclease P/MRP 40kDa subunit
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RRAGD Ras-related GTP binding D
RUFY3 RUN and FYVE domain containing 3
SAGE1 sarcoma antigen 1
SAMD12 sterile alpha motif domain containing 12
SCIN scinderin
SCN3B sodium channel, voltage gated, type III beta subunit
SCRN1 secernin 1
SDAD1 SDA1 domain containing 1
SDC1 syndecan 1
SEPT11 septin 11
SERPINB12 serpin peptidase inhibitor, clade B (ovalbumin), member 12
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SH3YL1 SH3 and SYLF domain containing 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SMC1A structural maintenance of chromosomes 1A
SMG7 SMG7 nonsense mediated mRNA decay factor
SND1-IT1 SND1 intronic transcript 1
SNORA15 small nucleolar RNA, H/ACA box 15
SNORA72 small nucleolar RNA, H/ACA box 72
SOWAHB sosondowah ankyrin repeat domain family member B
SOX13 SRY (sex determining region Y)-box 13
SPRR1A small proline-rich protein 1A
SRSF12 serine/arginine-rich splicing factor 12
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STON1 stonin 1
STRBP spermatid perinuclear RNA binding protein
STRN striatin, calmodulin binding protein
STX6 syntaxin 6
SUN1 Sad1 and UNC84 domain containing 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYT2 synaptotagmin II
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TBC1D25 TBC1 domain family, member 25
TCEA3 transcription elongation factor A (SII), 3
TDRD5 tudor domain containing 5
TET3 tet methylcytosine dioxygenase 3
TEX2 testis expressed 2
TFE3 transcription factor binding to IGHM enhancer 3
TGM5 transglutaminase 5
THAP9 THAP domain containing 9
THSD7A thrombospondin, type I, domain containing 7A
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1
TJP2 tight junction protein 2
TM2D2 TM2 domain containing 2
TMEM102 transmembrane protein 102
TMEM106B transmembrane protein 106B
TMEM79 transmembrane protein 79
TMPRSS11A transmembrane protease, serine 11A
TMPRSS11BNL TMPRSS11B N-terminal like, pseudogene
TMPRSS11D transmembrane protease, serine 11D
TMPRSS11F transmembrane protease, serine 11F
TNK2 tyrosine kinase, non-receptor, 2
TRAPPC2 trafficking protein particle complex 2
TRIM29 tripartite motif containing 29
TRNP1 TMF1-regulated nuclear protein 1
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC13 tetratricopeptide repeat domain 13
TTC22 tetratricopeptide repeat domain 22
TTC27 tetratricopeptide repeat domain 27
TTC9 tetratricopeptide repeat domain 9
TTLL12 tubulin tyrosine ligase-like family member 12
UBA1 ubiquitin-like modifier activating enzyme 1
UBA5 ubiquitin-like modifier activating enzyme 5
UBA6 ubiquitin-like modifier activating enzyme 6
UBQLN2 ubiquilin 2
UBXN2A UBX domain protein 2A
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
UGDH UDP-glucose 6-dehydrogenase
UPK3BL uroplakin 3B-like
USO1 USO1 vesicle transport factor
USP46 ubiquitin specific peptidase 46
USP9X ubiquitin specific peptidase 9, X-linked
VDAC3 voltage-dependent anion channel 3
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
WDFY3 WD repeat and FYVE domain containing 3
WDR13 WD repeat domain 13
WDR45 WD repeat domain 45
WDR60 WD repeat domain 60
WNK3 WNK lysine deficient protein kinase 3
YIPF4 Yip1 domain family, member 4
ZDHHC23 zinc finger, DHHC-type containing 23
ZNF148 zinc finger protein 148
ZNF182 zinc finger protein 182
ZNF41 zinc finger protein 41
ZNF674 zinc finger protein 674
ZNF81 zinc finger protein 81
ZNF823 zinc finger protein 823
ZXDC ZXD family zinc finger C

low expression

Symbol Name
CDADC1 cytidine and dCMP deaminase domain containing 1
GLT8D1 glycosyltransferase 8 domain containing 1
KIAA1143 KIAA1143