Lung squamous cell carcinoma_LUSC_TCGA-22-5492-01A-01R-1635-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

375 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-22-5492-01A-01R-1635-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ABHD8 abhydrolase domain containing 8
ACOX3 acyl-CoA oxidase 3, pristanoyl
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
ADAM6 ADAM metallopeptidase domain 6 (pseudogene)
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADRBK2 adrenergic, beta, receptor kinase 2
AFTPH aftiphilin
AGFG2 ArfGAP with FG repeats 2
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AGO4 argonaute RISC catalytic component 4
ALAD aminolevulinate dehydratase
ALOX15 arachidonate 15-lipoxygenase
ANKRD36 ankyrin repeat domain 36
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APCDD1 adenomatosis polyposis coli down-regulated 1
ARG2 arginase 2
ATE1 arginyltransferase 1
ATF7IP activating transcription factor 7 interacting protein
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATMIN ATM interactor
ATP9A ATPase, class II, type 9A
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
BAHD1 bromo adjacent homology domain containing 1
BCAR1 breast cancer anti-estrogen resistance 1
BCL2L15 BCL2-like 15
BCO1 beta-carotene oxygenase 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRDT bromodomain, testis-specific
BROX BRO1 domain and CAAX motif containing
BTBD8 BTB (POZ) domain containing 8
BTG3 BTG family, member 3
C2ORF88 chromosome 2 open reading frame 88
C4ORF19 chromosome 4 open reading frame 19
C9ORF106 chromosome 9 open reading frame 106
C9ORF129 chromosome 9 open reading frame 129
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CADM4 cell adhesion molecule 4
CADPS2 Ca++-dependent secretion activator 2
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAPN13 calpain 13
CARD6 caspase recruitment domain family, member 6
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC148 coiled-coil domain containing 148
CCDC149 coiled-coil domain containing 149
CCDC160 coiled-coil domain containing 160
CCDC186 coiled-coil domain containing 186
CCL13 chemokine (C-C motif) ligand 13
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL24 chemokine (C-C motif) ligand 24
CCL26 chemokine (C-C motif) ligand 26
CCL28 chemokine (C-C motif) ligand 28
CCNB3 cyclin B3
CCR2 chemokine (C-C motif) receptor 2
CD1B CD1b molecule
CD209 CD209 molecule
CD69 CD69 molecule
CDC14B cell division cycle 14B
CDC14C cell division cycle 14C
CDH26 cadherin 26
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CECR2 cat eye syndrome chromosome region, candidate 2
CEMIP cell migration inducing protein, hyaluronan binding
CH25H cholesterol 25-hydroxylase
CHRM4 cholinergic receptor, muscarinic 4
CLEC10A C-type lectin domain family 10, member A
CLEC2A C-type lectin domain family 2, member A
CLEC2B C-type lectin domain family 2, member B
CLEC4G C-type lectin domain family 4, member G
CLSTN2 calsyntenin 2
CMYA5 cardiomyopathy associated 5
CNTLN centlein, centrosomal protein
CNTNAP3 contactin associated protein-like 3
COA5 cytochrome c oxidase assembly factor 5
COG5 component of oligomeric golgi complex 5
COL6A5 collagen, type VI, alpha 5
COX5B cytochrome c oxidase subunit Vb
CROT carnitine O-octanoyltransferase
CSRP2 cysteine and glycine-rich protein 2
CTBP2 C-terminal binding protein 2
CXADR coxsackie virus and adenovirus receptor
CYB5B cytochrome b5 type B (outer mitochondrial membrane)
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP4X1 cytochrome P450, family 4, subfamily X, polypeptide 1
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1
CYSLTR1 cysteinyl leukotriene receptor 1
CYYR1 cysteine/tyrosine-rich 1
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DBP D site of albumin promoter (albumin D-box) binding protein
DCAF11 DDB1 and CUL4 associated factor 11
DCAF8L1 DDB1 and CUL4 associated factor 8-like 1
DLG5 discs, large homolog 5 (Drosophila)
DMRTA1 DMRT-like family A1
DMXL2 Dmx-like 2
DPYD dihydropyrimidine dehydrogenase
DRD1 dopamine receptor D1
EDAR ectodysplasin A receptor
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ELN elastin
EML4 echinoderm microtubule associated protein like 4
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERBB3 erb-b2 receptor tyrosine kinase 3
ERMN ermin, ERM-like protein
EXOC4 exocyst complex component 4
F13A1 coagulation factor XIII, A1 polypeptide
F2R coagulation factor II (thrombin) receptor
FAHD2B fumarylacetoacetate hydrolase domain containing 2B
FAM110C family with sequence similarity 110, member C
FAM160A1 family with sequence similarity 160, member A1
FAM161A family with sequence similarity 161, member A
FAM212B family with sequence similarity 212, member B
FBXL7 F-box and leucine-rich repeat protein 7
FMN1 formin 1
FRMPD4 FERM and PDZ domain containing 4
FRRS1 ferric-chelate reductase 1
FSTL4 follistatin-like 4
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GATSL2 GATS protein-like 2
GDNF glial cell derived neurotrophic factor
GLIS3 GLIS family zinc finger 3
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNPDA1 glucosamine-6-phosphate deaminase 1
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPR156 G protein-coupled receptor 156
GPRC5B G protein-coupled receptor, class C, group 5, member B
GPRC6A G protein-coupled receptor, class C, group 6, member A
GRID2 glutamate receptor, ionotropic, delta 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2I general transcription factor IIi
GUCD1 guanylyl cyclase domain containing 1
H2BFM H2B histone family, member M
HCAR1 hydroxycarboxylic acid receptor 1
HIPK1 homeodomain interacting protein kinase 1
HIST1H1T histone cluster 1, H1t
HIST1H3E histone cluster 1, H3e
HMGXB3 HMG box domain containing 3
HOMER2 homer scaffolding protein 2
HPS4 Hermansky-Pudlak syndrome 4
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HSPA2 heat shock 70kDa protein 2
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGFBPL1 insulin-like growth factor binding protein-like 1
IGFL4 IGF-like family member 4
IGSF11 immunoglobulin superfamily, member 11
IL33 interleukin 33
IL5 interleukin 5
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IQGAP2 IQ motif containing GTPase activating protein 2
IRX5 iroquois homeobox 5
IRX6 iroquois homeobox 6
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KDM4A lysine (K)-specific demethylase 4A
KIAA1841 KIAA1841
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
KLHDC10 kelch domain containing 10
KLHL26 kelch-like family member 26
KRT23 keratin 23, type I
LAMB4 laminin, beta 4
LARP1 La ribonucleoprotein domain family, member 1
LDB1 LIM domain binding 1
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LEF1 lymphoid enhancer-binding factor 1
LGI1 leucine-rich, glioma inactivated 1
LGR6 leucine-rich repeat containing G protein-coupled receptor 6
LIPF lipase, gastric
LIPJ lipase, family member J
LMO2 LIM domain only 2 (rhombotin-like 1)
LPAR3 lysophosphatidic acid receptor 3
LRP4 low density lipoprotein receptor-related protein 4
LRRC17 leucine rich repeat containing 17
LRRC3B leucine rich repeat containing 3B
LRRC69 leucine rich repeat containing 69
LURAP1 leucine rich adaptor protein 1
MAGEE2 melanoma antigen family E2
MAN1A2 mannosidase, alpha, class 1A, member 2
MAN1C1 mannosidase, alpha, class 1C, member 1
MC3R melanocortin 3 receptor
MDH1 malate dehydrogenase 1, NAD (soluble)
MEIS1 Meis homeobox 1
MFSD4 major facilitator superfamily domain containing 4
MKL2 MKL/myocardin-like 2
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MOB1A MOB kinase activator 1A
MSX2 msh homeobox 2
MT1X metallothionein 1X
MTIF2 mitochondrial translational initiation factor 2
MTMR12 myotubularin related protein 12
MTMR8 myotubularin related protein 8
MTSS1L metastasis suppressor 1-like
MXD4 MAX dimerization protein 4
MYO10 myosin X
MYOF myoferlin
NCOA2 nuclear receptor coactivator 2
NDN necdin, melanoma antigen (MAGE) family member
NEO1 neogenin 1
NFIA nuclear factor I/A
NGFR nerve growth factor receptor
NHLRC2 NHL repeat containing 2
NIPAL2 NIPA-like domain containing 2
NMUR2 neuromedin U receptor 2
NNT nicotinamide nucleotide transhydrogenase
NOL9 nucleolar protein 9
NOS1 nitric oxide synthase 1 (neuronal)
NPHP3-AS1 NPHP3 antisense RNA 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRAP nebulin-related anchoring protein
NRXN3 neurexin 3
NTF3 neurotrophin 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
NYNRIN NYN domain and retroviral integrase containing
OR56B4 olfactory receptor, family 56, subfamily B, member 4
OR6C4 olfactory receptor, family 6, subfamily C, member 4
OR9K2 olfactory receptor, family 9, subfamily K, member 2
OTOP1 otopetrin 1
OTX1 orthodenticle homeobox 1
PAGE2 P antigen family, member 2 (prostate associated)
PANK3 pantothenate kinase 3
PAPOLG poly(A) polymerase gamma
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PAQR9 progestin and adipoQ receptor family member IX
PCDHA10 protocadherin alpha 10
PCDHA2 protocadherin alpha 2
PCDHA3 protocadherin alpha 3
PCDHB3 protocadherin beta 3
PCDHB5 protocadherin beta 5
PCDHB8 protocadherin beta 8
PCDHGB2 protocadherin gamma subfamily B, 2
PCDHGB5 protocadherin gamma subfamily B, 5
PCP4L1 Purkinje cell protein 4 like 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDGFD platelet derived growth factor D
PDZD8 PDZ domain containing 8
PER3 period circadian clock 3
PEX13 peroxisomal biogenesis factor 13
PEX26 peroxisomal biogenesis factor 26
PIAS2 protein inhibitor of activated STAT, 2
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLS1 plastin 1
PNPT1 polyribonucleotide nucleotidyltransferase 1
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPP1R1C protein phosphatase 1, regulatory (inhibitor) subunit 1C
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRMT9 protein arginine methyltransferase 9
PROKR1 prokineticin receptor 1
PTPDC1 protein tyrosine phosphatase domain containing 1
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PWWP2A PWWP domain containing 2A
RAG1 recombination activating gene 1
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RASL11B RAS-like, family 11, member B
RC3H2 ring finger and CCCH-type domains 2
RDH10 retinol dehydrogenase 10 (all-trans)
REL v-rel avian reticuloendotheliosis viral oncogene homolog
REST RE1-silencing transcription factor
RGS7BP regulator of G-protein signaling 7 binding protein
RNF148 ring finger protein 148
RNLS renalase, FAD-dependent amine oxidase
SAMD8 sterile alpha motif domain containing 8
SBF2 SET binding factor 2
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SERINC5 serine incorporator 5
SERTAD2 SERTA domain containing 2
SEZ6L seizure related 6 homolog (mouse)-like
SH3GL3 SH3-domain GRB2-like 3
SHROOM2 shroom family member 2
SIDT1 SID1 transmembrane family, member 1
SIX1 SIX homeobox 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC25A40 solute carrier family 25, member 40
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLK STE20-like kinase
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMIM3 small integral membrane protein 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNORA4 small nucleolar RNA, H/ACA box 4
SNORA51 small nucleolar RNA, H/ACA box 51
SNORA66 small nucleolar RNA, H/ACA box 66
SP5 Sp5 transcription factor
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
STIM2 stromal interaction molecule 2
STK39 serine threonine kinase 39
STOX1 storkhead box 1
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1
TADA2B transcriptional adaptor 2B
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TBC1D3P1-DHX40P1 TBC1D3P1-DHX40P1 readthrough transcribed pseudogene
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBX3 T-box 3
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TIGD2 tigger transposable element derived 2
TIGD6 tigger transposable element derived 6
TLL1 tolloid-like 1
TMEM131 transmembrane protein 131
TMEM184C transmembrane protein 184C
TMEM252 transmembrane protein 252
TMEM37 transmembrane protein 37
TP53I11 tumor protein p53 inducible protein 11
TRIM62 tripartite motif containing 62
TRIO trio Rho guanine nucleotide exchange factor
TRPS1 trichorhinophalangeal syndrome I
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TUSC1 tumor suppressor candidate 1
UGP2 UDP-glucose pyrophosphorylase 2
UNC50 unc-50 homolog (C. elegans)
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
USP34 ubiquitin specific peptidase 34
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VANGL1 VANGL planar cell polarity protein 1
VAV3 vav 3 guanine nucleotide exchange factor
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
VSTM1 V-set and transmembrane domain containing 1
VWA2 von Willebrand factor A domain containing 2
WDFY1 WD repeat and FYVE domain containing 1
WDPCP WD repeat containing planar cell polarity effector
WDR86 WD repeat domain 86
WNK3 WNK lysine deficient protein kinase 3
WNK4 WNK lysine deficient protein kinase 4
WNT16 wingless-type MMTV integration site family, member 16
WWP1 WW domain containing E3 ubiquitin protein ligase 1
XPO1 exportin 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZHX1 zinc fingers and homeoboxes 1
ZIK1 zinc finger protein interacting with K protein 1
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZNF131 zinc finger protein 131
ZNF134 zinc finger protein 134
ZNF135 zinc finger protein 135
ZNF28 zinc finger protein 28
ZNF347 zinc finger protein 347
ZNF398 zinc finger protein 398
ZNF436 zinc finger protein 436
ZNF468 zinc finger protein 468
ZNF518B zinc finger protein 518B
ZNF552 zinc finger protein 552
ZNF611 zinc finger protein 611
ZNF614 zinc finger protein 614
ZNF658 zinc finger protein 658
ZNF677 zinc finger protein 677
ZNF702P zinc finger protein 702, pseudogene
ZNF704 zinc finger protein 704
ZNF75A zinc finger protein 75a
ZNF772 zinc finger protein 772
ZNF79 zinc finger protein 79
ZNF816 zinc finger protein 816
ZSCAN20 zinc finger and SCAN domain containing 20
ZSWIM8 zinc finger, SWIM-type containing 8