Lung squamous cell carcinoma_LUSC_TCGA-22-5482-01A-01R-1635-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

423 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-22-5482-01A-01R-1635-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABLIM2 actin binding LIM protein family, member 2
ACD adrenocortical dysplasia homolog (mouse)
ACKR3 atypical chemokine receptor 3
ACO2 aconitase 2, mitochondrial
ADAMTSL5 ADAMTS-like 5
ADAP1 ArfGAP with dual PH domains 1
AHCYL1 adenosylhomocysteinase-like 1
AKIRIN2 akirin 2
AKR1C3 aldo-keto reductase family 1, member C3
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANKS3 ankyrin repeat and sterile alpha motif domain containing 3
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
ANXA8L1 annexin A8-like 1
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARPC5L actin related protein 2/3 complex, subunit 5-like
ASB6 ankyrin repeat and SOCS box containing 6
ASF1A anti-silencing function 1A histone chaperone
ASS1 argininosuccinate synthase 1
ASTN2 astrotactin 2
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
ATRN attractin
BCAS2 breast carcinoma amplified sequence 2
BCL10 B-cell CLL/lymphoma 10
BFSP1 beaded filament structural protein 1, filensin
BMP1 bone morphogenetic protein 1
BRD2 bromodomain containing 2
BRD7 bromodomain containing 7
C11ORF80 chromosome 11 open reading frame 80
C1ORF226 chromosome 1 open reading frame 226
C3ORF67 chromosome 3 open reading frame 67
C9ORF156 chromosome 9 open reading frame 156
C9ORF40 chromosome 9 open reading frame 40
C9ORF43 chromosome 9 open reading frame 43
C9ORF69 chromosome 9 open reading frame 69
C9ORF78 chromosome 9 open reading frame 78
C9ORF85 chromosome 9 open reading frame 85
C9ORF89 chromosome 9 open reading frame 89
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCDC25 coiled-coil domain containing 25
CD109 CD109 molecule
CD207 CD207 molecule, langerin
CDIP1 cell death-inducing p53 target 1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDK9 cyclin-dependent kinase 9
CENPP centromere protein P
CES2 carboxylesterase 2
CIZ1 CDKN1A interacting zinc finger protein 1
CKMT1A creatine kinase, mitochondrial 1A
CLCA2 chloride channel accessory 2
CLDN20 claudin 20
CNTN5 contactin 5
COL17A1 collagen, type XVII, alpha 1
COQ4 coenzyme Q4
COQ9 coenzyme Q9
COX19 COX19 cytochrome c oxidase assembly factor
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSRP2 cysteine and glycine-rich protein 2
CSRP2BP CSRP2 binding protein
CTSB cathepsin B
CYB561D1 cytochrome b561 family, member D1
CYB5R2 cytochrome b5 reductase 2
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DBNL drebrin-like
DCTN6 dynactin 6
DEAF1 DEAF1 transcription factor
DENND1A DENN/MADD domain containing 1A
DENND2C DENN/MADD domain containing 2C
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DMTN dematin actin binding protein
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
DOC2B double C2-like domains, beta
DOK4 docking protein 4
DPF1 D4, zinc and double PHD fingers family 1
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
DPP7 dipeptidyl-peptidase 7
DSG3 desmoglein 3
DUSP5P1 dual specificity phosphatase 5 pseudogene 1
E2F4 E2F transcription factor 4, p107/p130-binding
EBF4 early B-cell factor 4
ECM1 extracellular matrix protein 1
EDF1 endothelial differentiation-related factor 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF4H eukaryotic translation initiation factor 4H
ELMO3 engulfment and cell motility 3
ELP3 elongator acetyltransferase complex subunit 3
ENDOD1 endonuclease domain containing 1
ENDOG endonuclease G
EPHB3 EPH receptor B3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERMARD ER membrane-associated RNA degradation
ERP44 endoplasmic reticulum protein 44
EYA4 EYA transcriptional coactivator and phosphatase 4
EZR ezrin
FADS1 fatty acid desaturase 1
FAM114A1 family with sequence similarity 114, member A1
FAM120B family with sequence similarity 120B
FAM122A family with sequence similarity 122A
FAM132A family with sequence similarity 132, member A
FAM172A family with sequence similarity 172, member A
FAM192A family with sequence similarity 192, member A
FAM206A family with sequence similarity 206, member A
FAM213A family with sequence similarity 213, member A
FAM57A family with sequence similarity 57, member A
FAM66E family with sequence similarity 66, member E
FAM86B1 family with sequence similarity 86, member B1
FAM89A family with sequence similarity 89, member A
FANCE Fanconi anemia, complementation group E
FBXO25 F-box protein 25
FBXO39 F-box protein 39
FERMT1 fermitin family member 1
FGFBP1 fibroblast growth factor binding protein 1
FKBP1A FK506 binding protein 1A, 12kDa
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOLH1B folate hydrolase 1B
FOXK1 forkhead box K1
FPGS folylpolyglutamate synthase
FRG1 FSHD region gene 1
FSTL4 follistatin-like 4
FTSJ2 FtsJ RNA methyltransferase homolog 2 (E. coli)
GAL3ST4 galactose-3-O-sulfotransferase 4
GATSL2 GATS protein-like 2
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae)
GINM1 glycoprotein integral membrane 1
GINS3 GINS complex subunit 3 (Psf3 homolog)
GJA1 gap junction protein, alpha 1, 43kDa
GJB3 gap junction protein, beta 3, 31kDa
GJB5 gap junction protein, beta 5, 31.1kDa
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GPC1 glypican 1
GPR135 G protein-coupled receptor 135
GPRC5D G protein-coupled receptor, class C, group 5, member D
GSR glutathione reductase
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTM2P1 glutathione S-transferase mu 2 (muscle) pseudogene 1
GSTM4 glutathione S-transferase mu 4
GTDC1 glycosyltransferase-like domain containing 1
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
HAUS2 HAUS augmin-like complex, subunit 2
HKDC1 hexokinase domain containing 1
HM13 histocompatibility (minor) 13
HMOX2 heme oxygenase 2
HN1 hematological and neurological expressed 1
HR hair growth associated
HRAS Harvey rat sarcoma viral oncogene homolog
HRASLS HRAS-like suppressor
HSPB3 heat shock 27kDa protein 3
IARS isoleucyl-tRNA synthetase
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
IGSF3 immunoglobulin superfamily, member 3
IL31RA interleukin 31 receptor A
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
INTS10 integrator complex subunit 10
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ITFG1 integrin alpha FG-GAP repeat containing 1
ITGA6 integrin, alpha 6
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JUP junction plakoglobin
KATNA1 katanin p60 (ATPase containing) subunit A 1
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCTD9 potassium channel tetramerization domain containing 9
KHDC1 KH homology domain containing 1
KIAA0368 KIAA0368
KIF16B kinesin family member 16B
KPNA4 karyopherin alpha 4 (importin alpha 3)
KPRP keratinocyte proline-rich protein
KRT17 keratin 17, type I
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT6C keratin 6C, type II
KRTAP20-2 keratin associated protein 20-2
KRTAP21-2 keratin associated protein 21-2
LAMA3 laminin, alpha 3
LAMB3 laminin, beta 3
LAMC2 laminin, gamma 2
LCE3C late cornified envelope 3C
LOC285696 uncharacterized LOC285696
LOC401127 WD repeat domain 5 pseudogene
LOC440173 uncharacterized LOC440173
LOC646999 akirin 1 pseudogene
LONP2 lon peptidase 2, peroxisomal
LOXL4 lysyl oxidase-like 4
LPCAT2 lysophosphatidylcholine acyltransferase 2
LRP12 low density lipoprotein receptor-related protein 12
LRRC8A leucine rich repeat containing 8 family, member A
LTB4R leukotriene B4 receptor
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAN1B1 mannosidase, alpha, class 1B, member 1
MAP2 microtubule-associated protein 2
MAPKAP1 mitogen-activated protein kinase associated protein 1
MATN2 matrilin 2
MCPH1 microcephalin 1
MCTS2P malignant T cell amplified sequence 2, pseudogene
MED27 mediator complex subunit 27
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MFSD1 major facilitator superfamily domain containing 1
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MKKS McKusick-Kaufman syndrome
MKNK1 MAP kinase interacting serine/threonine kinase 1
MOB2 MOB kinase activator 2
MRPL18 mitochondrial ribosomal protein L18
MSANTD3 Myb/SANT-like DNA-binding domain containing 3
MTMR9 myotubularin related protein 9
MTRF1L mitochondrial translational release factor 1-like
MYO5A myosin VA (heavy chain 12, myoxin)
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit
NAE1 NEDD8 activating enzyme E1 subunit 1
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NCS1 neuronal calcium sensor 1
NDRG1 N-myc downstream regulated 1
NDRG4 NDRG family member 4
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NELFB negative elongation factor complex member B
NELL2 NEL-like 2 (chicken)
NGEF neuronal guanine nucleotide exchange factor
NGF nerve growth factor (beta polypeptide)
NMRK1 nicotinamide riboside kinase 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOV nephroblastoma overexpressed
NR1D1 nuclear receptor subfamily 1, group D, member 1
NRARP NOTCH-regulated ankyrin repeat protein
NRSN2 neurensin 2
NSFL1C NSFL1 (p97) cofactor (p47)
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NT5M 5',3'-nucleotidase, mitochondrial
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OR10R2 olfactory receptor, family 10, subfamily R, member 2
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene)
OR2W1 olfactory receptor, family 2, subfamily W, member 1
OTOP2 otopetrin 2
OTOP3 otopetrin 3
P3H2 prolyl 3-hydroxylase 2
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae)
PANK2 pantothenate kinase 2
PAX8 paired box 8
PC pyruvate carboxylase
PCBP3 poly(rC) binding protein 3
PCDHB14 protocadherin beta 14
PCDHB6 protocadherin beta 6
PCDHGB1 protocadherin gamma subfamily B, 1
PCSK5 proprotein convertase subtilisin/kexin type 5
PEX6 peroxisomal biogenesis factor 6
PGA4 pepsinogen 4, group I (pepsinogen A)
PHKB phosphorylase kinase, beta
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PIR pirin (iron-binding nuclear protein)
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
PITPNM3 PITPNM family member 3
PKLR pyruvate kinase, liver and RBC
PLD5 phospholipase D family, member 5
PNPLA1 patatin-like phospholipase domain containing 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
POMZP3 POM121 and ZP3 fusion
POPDC3 popeye domain containing 3
PORCN porcupine homolog (Drosophila)
PPARD peroxisome proliferator-activated receptor delta
PPIF peptidylprolyl isomerase F
PPL periplakin
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme
PPP6C protein phosphatase 6, catalytic subunit
PRNP prion protein
PRRX2 paired related homeobox 2
PSD3 pleckstrin and Sec7 domain containing 3
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PSMG3 proteasome (prosome, macropain) assembly chaperone 3
PTGFRN prostaglandin F2 receptor inhibitor
PTGR1 prostaglandin reductase 1
PTPDC1 protein tyrosine phosphatase domain containing 1
PYGB phosphorylase, glycogen; brain
RAB14 RAB14, member RAS oncogene family
RABEPK Rab9 effector protein with kelch motifs
RABGGTB Rab geranylgeranyltransferase, beta subunit
RAET1G retinoic acid early transcript 1G
RAET1K retinoic acid early transcript 1K pseudogene
RAET1L retinoic acid early transcript 1L
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALGDS ral guanine nucleotide dissociation stimulator
RAP2B RAP2B, member of RAS oncogene family
RARS2 arginyl-tRNA synthetase 2, mitochondrial
RASA2 RAS p21 protein activator 2
REEP1 receptor accessory protein 1
REEP4 receptor accessory protein 4
RGPD8 RANBP2-like and GRIP domain containing 8
RHBDD2 rhomboid domain containing 2
RHOD ras homolog family member D
RIC8A RIC8 guanine nucleotide exchange factor A
RIOK3 RIO kinase 3
RNF13 ring finger protein 13
RNF7 ring finger protein 7
RNH1 ribonuclease/angiogenin inhibitor 1
ROGDI rogdi homolog (Drosophila)
RPF1 ribosome production factor 1 homolog (S. cerevisiae)
RPL7L1 ribosomal protein L7-like 1
RPS4Y1 ribosomal protein S4, Y-linked 1
RRM1 ribonucleotide reductase M1
RSPRY1 ring finger and SPRY domain containing 1
SARS seryl-tRNA synthetase
SCN9A sodium channel, voltage gated, type IX alpha subunit
SDK1 sidekick cell adhesion molecule 1
SEPT5 septin 5
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFN stratifin
SGK223 homolog of rat pragma of Rnd2
SH3BP1 SH3-domain binding protein 1
SIRT3 sirtuin 3
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SLC35F3 solute carrier family 35, member F3
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMOC2 SPARC related modular calcium binding 2
SNORA11 small nucleolar RNA, H/ACA box 11
SNORA2B small nucleolar RNA, H/ACA box 2B
SNORA41 small nucleolar RNA, H/ACA box 41
SNRPB2 small nuclear ribonucleoprotein polypeptide B
SORBS3 sorbin and SH3 domain containing 3
SOX15 SRY (sex determining region Y)-box 15
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SRRM3 serine/arginine repetitive matrix 3
SRXN1 sulfiredoxin 1
ST7L suppression of tumorigenicity 7 like
STC2 stanniocalcin 2
STK32B serine/threonine kinase 32B
SUN1 Sad1 and UNC84 domain containing 1
SURF4 surfeit 4
SYK spleen tyrosine kinase
SYNDIG1 synapse differentiation inducing 1
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TBC1D14 TBC1 domain family, member 14
TCTEX1D2 Tctex1 domain containing 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFBI transforming growth factor, beta-induced, 68kDa
THBD thrombomodulin
TLK1 tousled-like kinase 1
TMEM105 transmembrane protein 105
TMEM200B transmembrane protein 200B
TMEM203 transmembrane protein 203
TMEM54 transmembrane protein 54
TMEM87A transmembrane protein 87A
TNC tenascin C
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TNNI3K TNNI3 interacting kinase
TOR1A torsin family 1, member A (torsin A)
TP63 tumor protein p63
TRA2B transformer 2 beta homolog (Drosophila)
TRADD TNFRSF1A-associated via death domain
TREML3P triggering receptor expressed on myeloid cells-like 3, pseudogene
TRIM16L tripartite motif containing 16-like
TRIM29 tripartite motif containing 29
TRIM32 tripartite motif containing 32
TRIM35 tripartite motif containing 35
TRIM7 tripartite motif containing 7
TSPAN14 tetraspanin 14
TSPAN7 tetraspanin 7
TTC4 tetratricopeptide repeat domain 4
TTLL11 tubulin tyrosine ligase-like family member 11
TTYH2 tweety family member 2
TXN thioredoxin
UBALD1 UBA-like domain containing 1
UBAP1 ubiquitin associated protein 1
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2
UBN1 ubinuclein 1
UBQLN1 ubiquilin 1
ULBP2 UL16 binding protein 2
ULBP3 UL16 binding protein 3
URM1 ubiquitin related modifier 1
USH1G Usher syndrome 1G (autosomal recessive)
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
VDAC2 voltage-dependent anion channel 2
VN1R5 vomeronasal 1 receptor 5 (gene/pseudogene)
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WNT2B wingless-type MMTV integration site family, member 2B
XPA xeroderma pigmentosum, complementation group A
XRN2 5'-3' exoribonuclease 2
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBED2 zinc finger, BED-type containing 2
ZBTB41 zinc finger and BTB domain containing 41
ZDHHC1 zinc finger, DHHC-type containing 1
ZDHHC18 zinc finger, DHHC-type containing 18
ZFAND2A zinc finger, AN1-type domain 2A
ZNF143 zinc finger protein 143
ZNF319 zinc finger protein 319
ZNF395 zinc finger protein 395
ZNF500 zinc finger protein 500
ZNF596 zinc finger protein 596
ZNF706 zinc finger protein 706

low expression

Symbol Name
ZMYM3 zinc finger, MYM-type 3