Lung squamous cell carcinoma_LUSC_TCGA-22-5473-01A-01R-1635-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

299 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-22-5473-01A-01R-1635-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACBD5 acyl-CoA binding domain containing 5
ACSL6 acyl-CoA synthetase long-chain family member 6
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
ADAM23 ADAM metallopeptidase domain 23
ADCK2 aarF domain containing kinase 2
ADCY3 adenylate cyclase 3
ADCY8 adenylate cyclase 8 (brain)
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AK3 adenylate kinase 3
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AKR1E2 aldo-keto reductase family 1, member E2
ANKMY2 ankyrin repeat and MYND domain containing 2
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOBEC3D apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
ARMC10 armadillo repeat containing 10
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
ASF1A anti-silencing function 1A histone chaperone
ASPH aspartate beta-hydroxylase
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3
B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3
BAIAP2L2 BAI1-associated protein 2-like 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BMS1 BMS1 ribosome biogenesis factor
BTBD2 BTB (POZ) domain containing 2
BTBD6 BTB (POZ) domain containing 6
C12ORF56 chromosome 12 open reading frame 56
C16ORF13 chromosome 16 open reading frame 13
C17ORF105 chromosome 17 open reading frame 105
C7ORF50 chromosome 7 open reading frame 50
C9ORF114 chromosome 9 open reading frame 114
C9ORF89 chromosome 9 open reading frame 89
CABP5 calcium binding protein 5
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CALML3 calmodulin-like 3
CBR1 carbonyl reductase 1
CD9 CD9 molecule
CDC123 cell division cycle 123
CDC37L1 cell division cycle 37-like 1
CERS5 ceramide synthase 5
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2
CHRM3 cholinergic receptor, muscarinic 3
CNPY4 canopy FGF signaling regulator 4
CNTLN centlein, centrosomal protein
COPS5 COP9 signalosome subunit 5
COPS7A COP9 signalosome subunit 7A
CPA6 carboxypeptidase A6
CPNE8 copine VIII
CRMP1 collapsin response mediator protein 1
CRYGS crystallin, gamma S
CSTL1 cystatin-like 1
CUX1 cut-like homeobox 1
CYB561D2 cytochrome b561 family, member D2
DBF4 DBF4 zinc finger
DBNL drebrin-like
DCC DCC netrin 1 receptor
DCDC1 doublecortin domain containing 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEXI Dexi homolog (mouse)
DHRSX dehydrogenase/reductase (SDR family) X-linked
DLD dihydrolipoamide dehydrogenase
DMRT2 doublesex and mab-3 related transcription factor 2
DMRT3 doublesex and mab-3 related transcription factor 3
DMRTA1 DMRT-like family A1
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DUSP14 dual specificity phosphatase 14
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
EIF1 eukaryotic translation initiation factor 1
EIF3B eukaryotic translation initiation factor 3, subunit B
EMD emerin
EPS8 epidermal growth factor receptor pathway substrate 8
ERMP1 endoplasmic reticulum metallopeptidase 1
ETFB electron-transfer-flavoprotein, beta polypeptide
EXT1 exostosin glycosyltransferase 1
FAM134C family with sequence similarity 134, member C
FAM201A family with sequence similarity 201, member A
FLOT2 flotillin 2
FLYWCH1 FLYWCH-type zinc finger 1
FNTA farnesyltransferase, CAAX box, alpha
FREM2 FRAS1 related extracellular matrix protein 2
FRRS1L ferric-chelate reductase 1-like
FSCN1 fascin actin-bundling protein 1
FSTL4 follistatin-like 4
FUT10 fucosyltransferase 10 (alpha (1,3) fucosyltransferase)
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GCSH glycine cleavage system protein H (aminomethyl carrier)
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GPR26 G protein-coupled receptor 26
HCRTR2 hypocretin (orexin) receptor 2
HNRNPF heterogeneous nuclear ribonucleoprotein F
HOXA10 homeobox A10
HOXA4 homeobox A4
HOXA7 homeobox A7
HPRT1 hypoxanthine phosphoribosyltransferase 1
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5
HSPA14 heat shock 70kDa protein 14
IGFBP3 insulin-like growth factor binding protein 3
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
JOSD1 Josephin domain containing 1
KCMF1 potassium channel modulatory factor 1
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KDM4C lysine (K)-specific demethylase 4C
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA1549L KIAA1549-like
KIAA2026 KIAA2026
KLHL42 kelch-like family member 42
KRT13 keratin 13, type I
KRT15 keratin 15, type I
KRTAP21-2 keratin associated protein 21-2
KRTAP4-1 keratin associated protein 4-1
KRTAP4-8 keratin associated protein 4-8
KRTCAP3 keratinocyte associated protein 3
LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
LARP4B La ribonucleoprotein domain family, member 4B
LCE1F late cornified envelope 1F
LCE3B late cornified envelope 3B
LINGO2 leucine rich repeat and Ig domain containing 2
LMF1 lipase maturation factor 1
LOC374443 C-type lectin domain family 2, member D pseudogene
LOH12CR1 loss of heterozygosity, 12, chromosomal region 1
LPCAT3 lysophosphatidylcholine acyltransferase 3
LPPR1 lipid phosphate phosphatase-related protein type 1
LRRC28 leucine rich repeat containing 28
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LUZP2 leucine zipper protein 2
M6PR mannose-6-phosphate receptor (cation dependent)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEB6 melanoma antigen family B6
MANSC1 MANSC domain containing 1
MASTL microtubule associated serine/threonine kinase-like
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MEPCE methylphosphate capping enzyme
METTL22 methyltransferase like 22
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MMP11 matrix metallopeptidase 11
MRAP2 melanocortin 2 receptor accessory protein 2
MSANTD3 Myb/SANT-like DNA-binding domain containing 3
MTFMT mitochondrial methionyl-tRNA formyltransferase
MYO19 myosin XIX
NAMPT nicotinamide phosphoribosyltransferase
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NECAB2 N-terminal EF-hand calcium binding protein 2
NELL2 NEL-like 2 (chicken)
NKAIN2 Na+/K+ transporting ATPase interacting 2
NKAIN3 Na+/K+ transporting ATPase interacting 3
NKD2 naked cuticle homolog 2 (Drosophila)
NME4 NME/NM23 nucleoside diphosphate kinase 4
NMRAL1 NmrA-like family domain containing 1
NRBP1 nuclear receptor binding protein 1
NRN1 neuritin 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5
ODC1 ornithine decarboxylase 1
OLFM1 olfactomedin 1
PARD3 par-3 family cell polarity regulator
PCBP3 poly(rC) binding protein 3
PCDHGA10 protocadherin gamma subfamily A, 10
PDAP1 PDGFA associated protein 1
PEPD peptidase D
PFKP phosphofructokinase, platelet
PHTF2 putative homeodomain transcription factor 2
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLA2R1 phospholipase A2 receptor 1, 180kDa
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PMM2 phosphomannomutase 2
PMS2P1 postmeiotic segregation increased 2 pseudogene 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PMS2P4 postmeiotic segregation increased 2 pseudogene 4
PPAP2C phosphatidic acid phosphatase type 2C
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2
PPHLN1 periphilin 1
PPP1R35 protein phosphatase 1, regulatory subunit 35
PRDX2 peroxiredoxin 2
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PTDSS1 phosphatidylserine synthase 1
PTHLH parathyroid hormone-like hormone
PTPRD protein tyrosine phosphatase, receptor type, D
PYCR2 pyrroline-5-carboxylate reductase family, member 2
RAB18 RAB18, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RANBP6 RAN binding protein 6
RBM17 RNA binding motif protein 17
RCL1 RNA terminal phosphate cyclase-like 1
RELL2 RELT-like 2
REPS1 RALBP1 associated Eps domain containing 1
RFX3 regulatory factor X, 3 (influences HLA class II expression)
RGS20 regulator of G-protein signaling 20
RGS8 regulator of G-protein signaling 8
RHBDD2 rhomboid domain containing 2
RIC1 RAB6A GEF complex partner 1
RNF126 ring finger protein 126
RNF170 ring finger protein 170
RNF216 ring finger protein 216
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
RPS2 ribosomal protein S2
RPS28 ribosomal protein S28
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SDK1 sidekick cell adhesion molecule 1
SEPHS1 selenophosphate synthetase 1
SH3BP1 SH3-domain binding protein 1
SHISA9 shisa family member 9
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC16A14 solute carrier family 16, member 14
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A40 solute carrier family 25, member 40
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC35G1 solute carrier family 35, member G1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMIM19 small integral membrane protein 19
SMO smoothened, frizzled class receptor
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SNHG20 small nucleolar RNA host gene 20
SNORA44 small nucleolar RNA, H/ACA box 44
SNX17 sorting nexin 17
SPATA19 spermatogenesis associated 19
SPDYE3 speedy/RINGO cell cycle regulator family member E3
SRPK2 SRSF protein kinase 2
SRY sex determining region Y
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STK32B serine/threonine kinase 32B
STOML1 stomatin (EPB72)-like 1
SYCE1 synaptonemal complex central element protein 1
SYNDIG1 synapse differentiation inducing 1
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TBX20 T-box 20
TCEA1 transcription elongation factor A (SII), 1
TCTEX1D2 Tctex1 domain containing 2
TEAD2 TEA domain family member 2
TEX264 testis expressed 264
TFRC transferrin receptor
TGS1 trimethylguanosine synthase 1
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast)
TKT transketolase
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLX3 T-cell leukemia homeobox 3
TMED4 transmembrane emp24 protein transport domain containing 4
TMEM116 transmembrane protein 116
TMEM261 transmembrane protein 261
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast)
TOR1A torsin family 1, member A (torsin A)
TPI1 triosephosphate isomerase 1
TRAF4 TNF receptor-associated factor 4
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
TREX1 three prime repair exonuclease 1
TRIM16L tripartite motif containing 16-like
TRIP6 thyroid hormone receptor interactor 6
TTC39B tetratricopeptide repeat domain 39B
TTI2 TELO2 interacting protein 2
TTL tubulin tyrosine ligase
TUBA1C tubulin, alpha 1c
TYRP1 tyrosinase-related protein 1
UFSP1 UFM1-specific peptidase 1 (non-functional)
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
UNC119 unc-119 homolog (C. elegans)
URM1 ubiquitin related modifier 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
UST uronyl-2-sulfotransferase
UXS1 UDP-glucuronate decarboxylase 1
VDAC3 voltage-dependent anion channel 3
VLDLR very low density lipoprotein receptor
WAC WW domain containing adaptor with coiled-coil
WBP11 WW domain binding protein 11
WDR24 WD repeat domain 24
WDR54 WD repeat domain 54
WNT5B wingless-type MMTV integration site family, member 5B
XPOT exportin, tRNA
ZC3HC1 zinc finger, C3HC-type containing 1
ZDHHC4 zinc finger, DHHC-type containing 4
ZNF12 zinc finger protein 12
ZNF174 zinc finger protein 174
ZNF414 zinc finger protein 414
ZP3 zona pellucida glycoprotein 3 (sperm receptor)

low expression

Symbol Name
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
PARG poly (ADP-ribose) glycohydrolase