Lung squamous cell carcinoma_LUSC_TCGA-21-1070-01A-01R-0692-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

324 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-21-1070-01A-01R-0692-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABHD17C abhydrolase domain containing 17C
ACER3 alkaline ceramidase 3
ACOT11 acyl-CoA thioesterase 11
ADAM28 ADAM metallopeptidase domain 28
ADGRF3 adhesion G protein-coupled receptor F3
ADGRF4 adhesion G protein-coupled receptor F4
AFAP1L2 actin filament associated protein 1-like 2
AIM2 absent in melanoma 2
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2
ANKRD22 ankyrin repeat domain 22
ANKRD36 ankyrin repeat domain 36
ANO4 anoctamin 4
APOL6 apolipoprotein L, 6
AQP3 aquaporin 3 (Gill blood group)
AQP7P3 aquaporin 7 pseudogene 3
ARHGAP32 Rho GTPase activating protein 32
ASMTL-AS1 ASMTL antisense RNA 1
ATL2 atlastin GTPase 2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BATF2 basic leucine zipper transcription factor, ATF-like 2
BCAS4 breast carcinoma amplified sequence 4
BDKRB2 bradykinin receptor B2
BLNK B-cell linker
BORA bora, aurora kinase A activator
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BUB3 BUB3 mitotic checkpoint protein
C10ORF12 chromosome 10 open reading frame 12
C10ORF55 chromosome 10 open reading frame 55
C12ORF4 chromosome 12 open reading frame 4
C1QL1 complement component 1, q subcomponent-like 1
C1R complement component 1, r subcomponent
C20ORF197 chromosome 20 open reading frame 197
C5ORF52 chromosome 5 open reading frame 52
C6ORF62 chromosome 6 open reading frame 62
CA13 carbonic anhydrase XIII
CACUL1 CDK2-associated, cullin domain 1
CAMTA1 calmodulin binding transcription activator 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CCDC109B coiled-coil domain containing 109B
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CCNE1 cyclin E1
CCNE2 cyclin E2
CD2AP CD2-associated protein
CD300LD CD300 molecule-like family member d
CD47 CD47 molecule
CD6 CD6 molecule
CDC16 cell division cycle 16
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CFAP46 cilia and flagella associated protein 46
CGGBP1 CGG triplet repeat binding protein 1
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CHUK conserved helix-loop-helix ubiquitous kinase
CLEC2B C-type lectin domain family 2, member B
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
COL22A1 collagen, type XXII, alpha 1
CPEB3 cytoplasmic polyadenylation element binding protein 3
CST13P cystatin 13, pseudogene
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1
CXORF58 chromosome X open reading frame 58
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DCLRE1C DNA cross-link repair 1C
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
DEFB124 defensin, beta 124
DEFB131 defensin, beta 131
DENR density-regulated protein
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
DTX3L deltex 3 like, E3 ubiquitin ligase
DUSP22 dual specificity phosphatase 22
DUSP5 dual specificity phosphatase 5
E2F2 E2F transcription factor 2
ECM1 extracellular matrix protein 1
EFNA5 ephrin-A5
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EPSTI1 epithelial stromal interaction 1 (breast)
EQTN equatorin, sperm acrosome associated
ERAP2 endoplasmic reticulum aminopeptidase 2
ERMP1 endoplasmic reticulum metallopeptidase 1
ESPN espin
ETV7 ets variant 7
FAM111B family with sequence similarity 111, member B
FAM126B family with sequence similarity 126, member B
FAM169B family with sequence similarity 169, member B
FAM178A family with sequence similarity 178, member A
FAM213A family with sequence similarity 213, member A
FAM71F2 family with sequence similarity 71, member F2
FFAR2 free fatty acid receptor 2
FNBP4 formin binding protein 4
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GBP1 guanylate binding protein 1, interferon-inducible
GBP2 guanylate binding protein 2, interferon-inducible
GBP4 guanylate binding protein 4
GBP5 guanylate binding protein 5
GLB1L2 galactosidase, beta 1-like 2
GLDC glycine dehydrogenase (decarboxylating)
GOLGA6L1 golgin A6 family-like 1
GOLGA6L6 golgin A6 family-like 6
GPR143 G protein-coupled receptor 143
GPR150 G protein-coupled receptor 150
GPR180 G protein-coupled receptor 180
GPR25 G protein-coupled receptor 25
GSDMC gasdermin C
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HAPLN3 hyaluronan and proteoglycan link protein 3
HCAR2 hydroxycarboxylic acid receptor 2
HCAR3 hydroxycarboxylic acid receptor 3
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HEATR9 HEAT repeat containing 9
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HES2 hes family bHLH transcription factor 2
HIATL2 hippocampus abundant transcript-like 2
HMGN2 high mobility group nucleosomal binding domain 2
HSP90AB4P heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene
ICOS inducible T-cell co-stimulator
IDO1 indoleamine 2,3-dioxygenase 1
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFIH1 interferon induced with helicase C domain 1
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKZF2 IKAROS family zinc finger 2 (Helios)
IL12B interleukin 12B
IL12RB2 interleukin 12 receptor, beta 2
IL15RA interleukin 15 receptor, alpha
IL18 interleukin 18
INGX inhibitor of growth family, X-linked, pseudogene
IQSEC3 IQ motif and Sec7 domain 3
IRAK2 interleukin-1 receptor-associated kinase 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KLHL21 kelch-like family member 21
KLHL24 kelch-like family member 24
KRT39 keratin 39, type I
KRT78 keratin 78, type II
LAMP3 lysosomal-associated membrane protein 3
LAP3 leucine aminopeptidase 3
LGALS8 lectin, galactoside-binding, soluble, 8
LINC00242 long intergenic non-protein coding RNA 242
LOC284632 uncharacterized LOC284632
LRP11 low density lipoprotein receptor-related protein 11
LRRC1 leucine rich repeat containing 1
LYPD5 LY6/PLAUR domain containing 5
MAP6D1 MAP6 domain containing 1
MB21D1 Mab-21 domain containing 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MCFD2 multiple coagulation factor deficiency 2
MDFI MyoD family inhibitor
MED14 mediator complex subunit 14
MED20 mediator complex subunit 20
METTL10 methyltransferase like 10
MGC15885 uncharacterized protein MGC15885
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MLKL mixed lineage kinase domain-like
MOB3B MOB kinase activator 3B
MPZL2 myelin protein zero-like 2
MRS2P2 MRS2 pseudogene 2
MSH2 mutS homolog 2
MSL3 male-specific lethal 3 homolog (Drosophila)
MTAP methylthioadenosine phosphorylase
MYLK4 myosin light chain kinase family, member 4
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit
NEUROG1 neurogenin 1
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2
NMI N-myc (and STAT) interactor
NOL9 nucleolar protein 9
NOTCH2NL notch 2 N-terminal like
NT5C2 5'-nucleotidase, cytosolic II
NT5C3A 5'-nucleotidase, cytosolic IIIA
NUAK2 NUAK family, SNF1-like kinase, 2
OAF OAF homolog (Drosophila)
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OFD1 oral-facial-digital syndrome 1
OPTN optineurin
OR10G2 olfactory receptor, family 10, subfamily G, member 2
OR10H1 olfactory receptor, family 10, subfamily H, member 1
OR10H5 olfactory receptor, family 10, subfamily H, member 5
OR5B21 olfactory receptor, family 5, subfamily B, member 21
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARL presenilin associated, rhomboid-like
PARP11 poly (ADP-ribose) polymerase family, member 11
PARP14 poly (ADP-ribose) polymerase family, member 14
PARP9 poly (ADP-ribose) polymerase family, member 9
PATL1 protein associated with topoisomerase II homolog 1 (yeast)
PATL2 protein associated with topoisomerase II homolog 2 (yeast)
PDCD10 programmed cell death 10
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PHF13 PHD finger protein 13
PICALM phosphatidylinositol binding clathrin assembly protein
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PLA2G2F phospholipase A2, group IIF
PLBD1 phospholipase B domain containing 1
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
PLSCR1 phospholipid scramblase 1
POLH polymerase (DNA directed), eta
PPA1 pyrophosphatase (inorganic) 1
PPIAL4G peptidylprolyl isomerase A (cyclophilin A)-like 4G
PPIF peptidylprolyl isomerase F
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRDM1 PR domain containing 1, with ZNF domain
PRKCQ protein kinase C, theta
PRKD3 protein kinase D3
PRO0628 uncharacterized LOC29053
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PTP4A2 protein tyrosine phosphatase type IVA, member 2
RAB10 RAB10, member RAS oncogene family
RAB9A RAB9A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD9A RAD9 homolog A (S. pombe)
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RAPSN receptor-associated protein of the synapse
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RBBP7 retinoblastoma binding protein 7
RBM26 RNA binding motif protein 26
RBM45 RNA binding motif protein 45
RCOR1 REST corepressor 1
REXO2 RNA exonuclease 2
RHD Rh blood group, D antigen
RPS26 ribosomal protein S26
RRM2 ribonucleotide reductase M2
RSAD2 radical S-adenosyl methionine domain containing 2
RTN3 reticulon 3
SAMD9L sterile alpha motif domain containing 9-like
SATL1 spermidine/spermine N1-acetyl transferase-like 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SHROOM2 shroom family member 2
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC25A46 solute carrier family 25, member 46
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SLK STE20-like kinase
SMNDC1 survival motor neuron domain containing 1
SMTNL1 smoothelin-like 1
SNORA62 small nucleolar RNA, H/ACA box 62
SNX16 sorting nexin 16
SP1 Sp1 transcription factor
SP110 SP110 nuclear body protein
SPDYE2 speedy/RINGO cell cycle regulator family member E2
SPOCD1 SPOC domain containing 1
ST7-OT3 ST7 overlapping transcript 3
STAMBPL1 STAM binding protein-like 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STRADB STE20-related kinase adaptor beta
STRIP2 striatin interacting protein 2
STS steroid sulfatase (microsomal), isozyme S
STYK1 serine/threonine/tyrosine kinase 1
SYCP3 synaptonemal complex protein 3
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TARSL2 threonyl-tRNA synthetase-like 2
TBC1D12 TBC1 domain family, member 12
TEAD4 TEA domain family member 4
TEX30 testis expressed 30
TEX40 testis expressed 40
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
TLL2 tolloid-like 2
TMCC3 transmembrane and coiled-coil domain family 3
TMEM145 transmembrane protein 145
TMEM171 transmembrane protein 171
TMEM253 transmembrane protein 253
TMEM27 transmembrane protein 27
TPM3 tropomyosin 3
TPP2 tripeptidyl peptidase II
TRERF1 transcriptional regulating factor 1
TRIB2 tribbles pseudokinase 2
TRIM22 tripartite motif containing 22
TRIM34 tripartite motif containing 34
TRIM69 tripartite motif containing 69
TTLL13P tubulin tyrosine ligase-like family member 13, pseudogene
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
USP15 ubiquitin specific peptidase 15
USP18 ubiquitin specific peptidase 18
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
WARS tryptophanyl-tRNA synthetase
WDR64 WD repeat domain 64
WFDC8 WAP four-disulfide core domain 8
WRNIP1 Werner helicase interacting protein 1
WWC3 WWC family member 3
XAF1 XIAP associated factor 1
XIST X inactive specific transcript (non-protein coding)
XRN1 5'-3' exoribonuclease 1
YEATS2 YEATS domain containing 2
YOD1 YOD1 deubiquitinase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZBP1 Z-DNA binding protein 1
ZDHHC6 zinc finger, DHHC-type containing 6
ZNF114 zinc finger protein 114
ZNF487 zinc finger protein 487
ZNF654 zinc finger protein 654
ZNF80 zinc finger protein 80
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2