Lung squamous cell carcinoma_LUSC_TCGA-18-4721-01A-01R-1443-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

298 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-18-4721-01A-01R-1443-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ABHD4 abhydrolase domain containing 4
ACAT2 acetyl-CoA acetyltransferase 2
ACLY ATP citrate lyase
ACTL6A actin-like 6A
ADAM23 ADAM metallopeptidase domain 23
ADAMDEC1 ADAM-like, decysin 1
ADAT1 adenosine deaminase, tRNA-specific 1
ADCY8 adenylate cyclase 8 (brain)
ADD2 adducin 2 (beta)
AFF2 AF4/FMR2 family, member 2
AGA aspartylglucosaminidase
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALG3 ALG3, alpha-1,3- mannosyltransferase
ALKBH3 alkB, alkylation repair homolog 3 (E. coli)
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APOL4 apolipoprotein L, 4
APTX aprataxin
ARF4 ADP-ribosylation factor 4
ARPP21 cAMP-regulated phosphoprotein, 21kDa
ASF1A anti-silencing function 1A histone chaperone
ATF6 activating transcription factor 6
ATP10D ATPase, class V, type 10D
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
BAG5 BCL2-associated athanogene 5
BEND4 BEN domain containing 4
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BRAP BRCA1 associated protein
BRS3 bombesin-like receptor 3
C10ORF120 chromosome 10 open reading frame 120
C10ORF131 chromosome 10 open reading frame 131
C4ORF50 chromosome 4 open reading frame 50
C5ORF47 chromosome 5 open reading frame 47
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CALB1 calbindin 1, 28kDa
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CCNT1 cyclin T1
CCR9 chemokine (C-C motif) receptor 9
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDC40 cell division cycle 40
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDKN2AIP CDKN2A interacting protein
CES1P1 carboxylesterase 1 pseudogene 1
CFAP97 cilia and flagella associated protein 97
CFHR3 complement factor H-related 3
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COBLL1 cordon-bleu WH2 repeat protein-like 1
COMMD8 COMM domain containing 8
COPA coatomer protein complex, subunit alpha
CPLX4 complexin 4
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CPXCR1 CPX chromosome region, candidate 1
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CREB3 cAMP responsive element binding protein 3
CRMP1 collapsin response mediator protein 1
CSNK1G1 casein kinase 1, gamma 1
DCAF10 DDB1 and CUL4 associated factor 10
DCC DCC netrin 1 receptor
DCDC1 doublecortin domain containing 1
DCTD dCMP deaminase
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DERL1 derlin 1
DESI1 desumoylating isopeptidase 1
DICER1 dicer 1, ribonuclease type III
DIRC3 disrupted in renal carcinoma 3
DLD dihydrolipoamide dehydrogenase
DMRT2 doublesex and mab-3 related transcription factor 2
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNAJC25 DnaJ (Hsp40) homolog, subfamily C , member 25
DOLK dolichol kinase
DPF2 D4, zinc and double PHD fingers family 2
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
DYTN dystrotelin
ECE2 endothelin converting enzyme 2
ECT2 epithelial cell transforming 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF5 eukaryotic translation initiation factor 5
EIF5A2 eukaryotic translation initiation factor 5A2
EOMES eomesodermin
EXOSC3 exosome component 3
FAM120AOS family with sequence similarity 120A opposite strand
FAM91A1 family with sequence similarity 91, member A1
FBXL5 F-box and leucine-rich repeat protein 5
FBXO8 F-box protein 8
FCRLB Fc receptor-like B
FDPS farnesyl diphosphate synthase
FECH ferrochelatase
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FNDC3B fibronectin type III domain containing 3B
FRK fyn-related Src family tyrosine kinase
FSD2 fibronectin type III and SPRY domain containing 2
FSTL4 follistatin-like 4
FUT10 fucosyltransferase 10 (alpha (1,3) fucosyltransferase)
FXR1 fragile X mental retardation, autosomal homolog 1
GABPB2 GA binding protein transcription factor, beta subunit 2
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1
GAN gigaxonin
GAS2L3 growth arrest-specific 2 like 3
GATAD2B GATA zinc finger domain containing 2B
GCSH glycine cleavage system protein H (aminomethyl carrier)
GJB7 gap junction protein, beta 7, 25kDa
GLRX5 glutaredoxin 5
GMCL1 germ cell-less, spermatogenesis associated 1
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GOLGA5 golgin A5
GOLIM4 golgi integral membrane protein 4
GORASP2 golgi reassembly stacking protein 2, 55kDa
GOSR2 golgi SNAP receptor complex member 2
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPR85 G protein-coupled receptor 85
GPR89A G protein-coupled receptor 89A
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HACL1 2-hydroxyacyl-CoA lyase 1
HCRTR2 hypocretin (orexin) receptor 2
HINT2 histidine triad nucleotide binding protein 2
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IL17F interleukin 17F
INA internexin neuronal intermediate filament protein, alpha
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
KCNIP4 Kv channel interacting protein 4
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1
KCTD8 potassium channel tetramerization domain containing 8
KIAA2026 KIAA2026
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KLHL11 kelch-like family member 11
KLHL5 kelch-like family member 5
KRTAP4-1 keratin associated protein 4-1
LCLAT1 lysocardiolipin acyltransferase 1
LIN7A lin-7 homolog A (C. elegans)
LOC100130691 uncharacterized LOC100130691
LOC200726 hCG1657980
LPAR1 lysophosphatidic acid receptor 1
LPCAT3 lysophosphatidylcholine acyltransferase 3
LUZP2 leucine zipper protein 2
MAB21L1 mab-21-like 1 (C. elegans)
MAGEB18 melanoma antigen family B18
MAGEB2 melanoma antigen family B2
MAGEF1 melanoma antigen family F1
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MELK maternal embryonic leucine zipper kinase
MERTK MER proto-oncogene, tyrosine kinase
METAP2 methionyl aminopeptidase 2
MFN1 mitofusin 1
MRPL47 mitochondrial ribosomal protein L47
MSMO1 methylsterol monooxygenase 1
MTO1 mitochondrial tRNA translation optimization 1
NAIP NLR family, apoptosis inhibitory protein
NAMPT nicotinamide phosphoribosyltransferase
NCEH1 neutral cholesterol ester hydrolase 1
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
NEK1 NIMA-related kinase 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFXL1 nuclear transcription factor, X-box binding-like 1
NIPAL1 NIPA-like domain containing 1
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NLGN1 neuroligin 1
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NRCAM neuronal cell adhesion molecule
NUP98 nucleoporin 98kDa
OBP2A odorant binding protein 2A
OCIAD1 OCIA domain containing 1
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1
OLFM1 olfactomedin 1
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR1J2 olfactory receptor, family 1, subfamily J, member 2
OR1L8 olfactory receptor, family 1, subfamily L, member 8
OR2L1P olfactory receptor, family 2, subfamily L, member 1 pseudogene
OR6T1 olfactory receptor, family 6, subfamily T, member 1
OSBP oxysterol binding protein
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
PALLD palladin, cytoskeletal associated protein
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative)
PCDH17 protocadherin 17
PCDHGB5 protocadherin gamma subfamily B, 5
PDCD10 programmed cell death 10
PDE11A phosphodiesterase 11A
PEX12 peroxisomal biogenesis factor 12
PGM3 phosphoglucomutase 3
PHEX phosphate regulating endopeptidase homolog, X-linked
PHKB phosphorylase kinase, beta
PI4K2B phosphatidylinositol 4-kinase type 2 beta
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PIGW phosphatidylinositol glycan anchor biosynthesis, class W
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
PNPO pyridoxamine 5'-phosphate oxidase
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POLR1E polymerase (RNA) I polypeptide E, 53kDa
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
POU3F2 POU class 3 homeobox 2
PRDM13 PR domain containing 13
PRDX6 peroxiredoxin 6
PROX2 prospero homeobox 2
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PTDSS1 phosphatidylserine synthase 1
PTER phosphotriesterase related
RAD54L2 RAD54-like 2 (S. cerevisiae)
RC3H2 ring finger and CCCH-type domains 2
RELN reelin
RGS6 regulator of G-protein signaling 6
RIMBP3 RIMS binding protein 3
RIMBP3C RIMS binding protein 3C
RLN2 relaxin 2
RNF217 ring finger protein 217
RNF4 ring finger protein 4
RORB RAR-related orphan receptor B
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase
SC5D sterol-C5-desaturase
SCIN scinderin
SCYL2 SCY1-like 2 (S. cerevisiae)
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SESN3 sestrin 3
SGPP2 sphingosine-1-phosphate phosphatase 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SIPA1L2 signal-induced proliferation-associated 1 like 2
SLAIN2 SLAIN motif family, member 2
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC25A51 solute carrier family 25, member 51
SLC25A51P1 solute carrier family 25, member 51 pseudogene 1
SLC25A52 solute carrier family 25, member 52
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC35G1 solute carrier family 35, member G1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLFN5 schlafen family member 5
SMAP1 small ArfGAP 1
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SNX19 sorting nexin 19
SRPR signal recognition particle receptor (docking protein)
SRPRB signal recognition particle receptor, B subunit
STARD5 StAR-related lipid transfer (START) domain containing 5
STOX2 storkhead box 2
STRAP serine/threonine kinase receptor associated protein
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
SV2B synaptic vesicle glycoprotein 2B
SYT10 synaptotagmin X
SYT9 synaptotagmin IX
TBCEL tubulin folding cofactor E-like
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBL2 transducin (beta)-like 2
TEX261 testis expressed 261
THEMIS thymocyte selection associated
THSD7A thrombospondin, type I, domain containing 7A
TIGAR TP53 induced glycolysis regulatory phosphatase
TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough
TMEM229A transmembrane protein 229A
TMEM33 transmembrane protein 33
TMEM87A transmembrane protein 87A
TMTC1 transmembrane and tetratricopeptide repeat containing 1
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TNIK TRAF2 and NCK interacting kinase
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast)
TOR1A torsin family 1, member A (torsin A)
TRAF3 TNF receptor-associated factor 3
TRIM32 tripartite motif containing 32
TRIM4 tripartite motif containing 4
TTI2 TELO2 interacting protein 2
TXNL4A thioredoxin-like 4A
TXNL4B thioredoxin-like 4B
TYRP1 tyrosinase-related protein 1
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
UHMK1 U2AF homology motif (UHM) kinase 1
UHRF1BP1L UHRF1 binding protein 1-like
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
UST uronyl-2-sulfotransferase
VAMP4 vesicle-associated membrane protein 4
VCP valosin containing protein
WASF1 WAS protein family, member 1
XKR9 XK, Kell blood group complex subunit-related family, member 9
XPOT exportin, tRNA
YIPF7 Yip1 domain family, member 7
ZBTB38 zinc finger and BTB domain containing 38
ZBTB5 zinc finger and BTB domain containing 5
ZC3H14 zinc finger CCCH-type containing 14
ZCCHC7 zinc finger, CCHC domain containing 7
ZMAT3 zinc finger, matrin-type 3
ZNF639 zinc finger protein 639

low expression

Symbol Name
E4F1 E4F transcription factor 1