Lung squamous cell carcinoma_LUSC_TCGA-18-3414-01A-01R-0980-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

389 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-18-3414-01A-01R-0980-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACO2 aconitase 2, mitochondrial
ACSF3 acyl-CoA synthetase family member 3
ACYP2 acylphosphatase 2, muscle type
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2
ANKK1 ankyrin repeat and kinase domain containing 1
APIP APAF1 interacting protein
ARFIP1 ADP-ribosylation factor interacting protein 1
ARL14EP ADP-ribosylation factor-like 14 effector protein
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARSF arylsulfatase F
ASB6 ankyrin repeat and SOCS box containing 6
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
AUH AU RNA binding protein/enoyl-CoA hydratase
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAALC brain and acute leukemia, cytoplasmic
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BDNF-AS BDNF antisense RNA
BID BH3 interacting domain death agonist
BIN3 bridging integrator 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BRIX1 BRX1, biogenesis of ribosomes
C15ORF40 chromosome 15 open reading frame 40
C16ORF70 chromosome 16 open reading frame 70
C2ORF68 chromosome 2 open reading frame 68
C3ORF30 chromosome 3 open reading frame 30
C4ORF33 chromosome 4 open reading frame 33
C5ORF28 chromosome 5 open reading frame 28
C7ORF33 chromosome 7 open reading frame 33
C9ORF40 chromosome 9 open reading frame 40
C9ORF41 chromosome 9 open reading frame 41
C9ORF85 chromosome 9 open reading frame 85
CA13 carbonic anhydrase XIII
CAPG capping protein (actin filament), gelsolin-like
CAPNS2 calpain, small subunit 2
CAPRIN1 cell cycle associated protein 1
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBWD3 COBW domain containing 3
CBWD6 COBW domain containing 6
CCDC152 coiled-coil domain containing 152
CCDC6 coiled-coil domain containing 6
CCDC73 coiled-coil domain containing 73
CCL28 chemokine (C-C motif) ligand 28
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CCR3 chemokine (C-C motif) receptor 3
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CD99 CD99 molecule
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5
CDH18 cadherin 18, type 2
CDK20 cyclin-dependent kinase 20
CENPBD1 CENPB DNA-binding domains containing 1
CHKB choline kinase beta
CHODL-AS1 CHODL antisense RNA 1
CIAPIN1 cytokine induced apoptosis inhibitor 1
CIB2 calcium and integrin binding family member 2
CLCA3P chloride channel accessory 3, pseudogene
CLEC2L C-type lectin domain family 2, member L
CMTM1 CKLF-like MARVEL transmembrane domain containing 1
CNOT7 CCR4-NOT transcription complex, subunit 7
COG4 component of oligomeric golgi complex 4
COMMD1 copper metabolism (Murr1) domain containing 1
COMMD9 COMM domain containing 9
CORO2A coronin, actin binding protein, 2A
CPNE2 copine II
CTF1 cardiotrophin 1
CTNNA2 catenin (cadherin-associated protein), alpha 2
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe)
CXCL6 chemokine (C-X-C motif) ligand 6
CXCR2 chemokine (C-X-C motif) receptor 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DCAF4 DDB1 and CUL4 associated factor 4
DCTN6 dynactin 6
DEFB1 defensin, beta 1
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
ELMOD3 ELMO/CED-12 domain containing 3
ELP3 elongator acetyltransferase complex subunit 3
ELP4 elongator acetyltransferase complex subunit 4
EMC8 ER membrane protein complex subunit 8
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7
EPHA4 EPH receptor A4
ERP44 endoplasmic reticulum protein 44
EXOC3 exocyst complex component 3
FAM120A family with sequence similarity 120A
FAM120AOS family with sequence similarity 120A opposite strand
FAM122A family with sequence similarity 122A
FAM133A family with sequence similarity 133, member A
FAM173B family with sequence similarity 173, member B
FAM192A family with sequence similarity 192, member A
FAM228A family with sequence similarity 228, member A
FANCF Fanconi anemia, complementation group F
FASTKD3 FAST kinase domains 3
FBXO3 F-box protein 3
FBXO4 F-box protein 4
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FMO3 flavin containing monooxygenase 3
FMO4 flavin containing monooxygenase 4
FOXD4L3 forkhead box D4-like 3
FOXD4L6 forkhead box D4-like 6
FSD2 fibronectin type III and SPRY domain containing 2
FXN frataxin
GAGE13 G antigen 13
GGCX gamma-glutamyl carboxylase
GHR growth hormone receptor
GLUL glutamate-ammonia ligase
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPR137B G protein-coupled receptor 137B
GPR89B G protein-coupled receptor 89B
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
HADH hydroxyacyl-CoA dehydrogenase
HAPLN1 hyaluronan and proteoglycan link protein 1
HIST1H1T histone cluster 1, H1t
HIST1H2AB histone cluster 1, H2ab
HIST1H2AC histone cluster 1, H2ac
HIST1H2AD histone cluster 1, H2ad
HIST1H2AE histone cluster 1, H2ae
HIST1H2AG histone cluster 1, H2ag
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AK histone cluster 1, H2ak
HIST1H2AL histone cluster 1, H2al
HIST1H2AM histone cluster 1, H2am
HIST1H2BC histone cluster 1, H2bc
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BG histone cluster 1, H2bg
HIST1H2BK histone cluster 1, H2bk
HIST1H2BM histone cluster 1, H2bm
HIST1H2BO histone cluster 1, H2bo
HIST1H3A histone cluster 1, H3a
HIST1H3B histone cluster 1, H3b
HIST1H3C histone cluster 1, H3c
HIST1H3D histone cluster 1, H3d
HIST1H3E histone cluster 1, H3e
HIST1H3G histone cluster 1, H3g
HIST1H3H histone cluster 1, H3h
HIST1H3J histone cluster 1, H3j
HIST1H4D histone cluster 1, H4d
HIST1H4E histone cluster 1, H4e
HIST1H4F histone cluster 1, H4f
HIST1H4H histone cluster 1, H4h
HIST1H4I histone cluster 1, H4i
HIST2H2AA3 histone cluster 2, H2aa3
HIST2H2AB histone cluster 2, H2ab
HIST2H2BA histone cluster 2, H2ba (pseudogene)
HIST2H2BE histone cluster 2, H2be
HIST2H2BF histone cluster 2, H2bf
HIST2H3D histone cluster 2, H3d
HIST2H4A histone cluster 2, H4a
HIST3H2A histone cluster 3, H2a
HIST3H2BB histone cluster 3, H2bb
HOXB2 homeobox B2
HOXD3 homeobox D3
HOXD4 homeobox D4
HTN3 histatin 3
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IGSF22 immunoglobulin superfamily, member 22
IL1RL2 interleukin 1 receptor-like 2
IMMT inner membrane protein, mitochondrial
INTS10 integrator complex subunit 10
IRX5 iroquois homeobox 5
ISCA1 iron-sulfur cluster assembly 1
ISOC2 isochorismatase domain containing 2
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KBTBD12 kelch repeat and BTB (POZ) domain containing 12
KCMF1 potassium channel modulatory factor 1
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCTD9 potassium channel tetramerization domain containing 9
KGFLP1 fibroblast growth factor 7 pseudogene
KIAA1841 KIAA1841
KNCN kinocilin
KRT72 keratin 72, type II
KRTAP10-2 keratin associated protein 10-2
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
LGALS8 lectin, galactoside-binding, soluble, 8
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LIN7C lin-7 homolog C (C. elegans)
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC284798 uncharacterized LOC284798
LOC440173 uncharacterized LOC440173
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1
LRRN4CL LRRN4 C-terminal like
LSMEM2 leucine-rich single-pass membrane protein 2
MACC1 metastasis associated in colon cancer 1
MAGEA4 melanoma antigen family A4
MAGEA5 melanoma antigen family A5
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MCPH1 microcephalin 1
MCU mitochondrial calcium uniporter
MDH1 malate dehydrogenase 1, NAD (soluble)
MECR mitochondrial trans-2-enoyl-CoA reductase
MED10 mediator complex subunit 10
MORC2-AS1 MORC2 antisense RNA 1
MORF4L1 mortality factor 4 like 1
MPPED2 metallophosphoesterase domain containing 2
MRGPRX2 MAS-related GPR, member X2
MRPL50 mitochondrial ribosomal protein L50
MRPS11 mitochondrial ribosomal protein S11
MRPS30 mitochondrial ribosomal protein S30
MTHFSD methenyltetrahydrofolate synthetase domain containing
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NIP7 NIP7, nucleolar pre-rRNA processing protein
NIPSNAP3A nipsnap homolog 3A (C. elegans)
NKX6-3 NK6 homeobox 3
NLGN4Y neuroligin 4, Y-linked
NPAS3 neuronal PAS domain protein 3
NSG1 neuron specific gene family member 1
NT5C2 5'-nucleotidase, cytosolic II
NUTF2 nuclear transport factor 2
NXT2 nuclear transport factor 2-like export factor 2
ODF3L1 outer dense fiber of sperm tails 3-like 1
OR1L6 olfactory receptor, family 1, subfamily L, member 6
OR8D2 olfactory receptor, family 8, subfamily D, member 2 (gene/pseudogene)
OR9K2 olfactory receptor, family 9, subfamily K, member 2
PAIP1 poly(A) binding protein interacting protein 1
PANX3 pannexin 3
PAPOLG poly(A) polymerase gamma
PAX1 paired box 1
PAX6 paired box 6
PCDHB14 protocadherin beta 14
PCDHGA11 protocadherin gamma subfamily A, 11
PDCD6 programmed cell death 6
PEX11A peroxisomal biogenesis factor 11 alpha
PEX13 peroxisomal biogenesis factor 13
PEX2 peroxisomal biogenesis factor 2
PGPEP1L pyroglutamyl-peptidase I-like
PHKB phosphorylase kinase, beta
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PLGLA plasminogen-like A (pseudogene)
PNMA5 paraneoplastic Ma antigen family member 5
PPAPDC3 phosphatidic acid phosphatase type 2 domain containing 3
PPIAL4E peptidylprolyl isomerase A (cyclophilin A)-like 4E
PPP1R21 protein phosphatase 1, regulatory subunit 21
PPP1R3B protein phosphatase 1, regulatory subunit 3B
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRMT1 protein arginine methyltransferase 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSKH1 protein serine kinase H1
PTAR1 protein prenyltransferase alpha subunit repeat containing 1
PTCD3 pentatricopeptide repeat domain 3
PTPN20 protein tyrosine phosphatase, non-receptor type 20
PUS10 pseudouridylate synthase 10
R3HCC1 R3H domain and coiled-coil containing 1
RAB25 RAB25, member RAS oncogene family
RABL3 RAB, member of RAS oncogene family-like 3
RAD1 RAD1 checkpoint DNA exonuclease
RALYL RALY RNA binding protein-like
RBMY1A3P RNA binding motif protein, Y-linked, family 1, member A3 pseudogene
REG1B regenerating islet-derived 1 beta
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RERG RAS-like, estrogen-regulated, growth inhibitor
RESP18 regulated endocrine-specific protein 18
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RMI1 RecQ mediated genome instability 1
RNF181 ring finger protein 181
RNF2 ring finger protein 2
RNFT2 ring finger protein, transmembrane 2
RSPRY1 ring finger and SPRY domain containing 1
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1
SENP7 SUMO1/sentrin specific peptidase 7
SEPW1 selenoprotein W, 1
SERHL2 serine hydrolase-like 2
SETMAR SET domain and mariner transposase fusion gene
SH2D4A SH2 domain containing 4A
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3
SLC9B1 solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
SMC5 structural maintenance of chromosomes 5
SMEK3P SMEK homolog 3, suppressor of mek1 (Dictyostelium) pseudogene
SPHAR S-phase response (cyclin related)
SPIN1 spindlin 1
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SRY sex determining region Y
STOML1 stomatin (EPB72)-like 1
SUB1 SUB1 homolog (S. cerevisiae)
SUCLG1 succinate-CoA ligase, alpha subunit
SYNGR1 synaptogyrin 1
TACR1 tachykinin receptor 1
TBC1D10A TBC1 domain family, member 10A
TBCK TBC1 domain containing kinase
TBR1 T-box, brain, 1
TCF25 transcription factor 25 (basic helix-loop-helix)
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TDRD1 tudor domain containing 1
TDRG1 testis development related 1 (non-protein coding)
TEX10 testis expressed 10
TGIF2LX TGFB-induced factor homeobox 2-like, X-linked
TGIF2LY TGFB-induced factor homeobox 2-like, Y-linked
THAP2 THAP domain containing, apoptosis associated protein 2
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TINCR tissue differentiation-inducing non-protein coding RNA
TJP2 tight junction protein 2
TLE4 transducin-like enhancer of split 4
TMED3 transmembrane emp24 protein transport domain containing 3
TMEM143 transmembrane protein 143
TMEM150A transmembrane protein 150A
TMEM19 transmembrane protein 19
TMEM230 transmembrane protein 230
TMEM71 transmembrane protein 71
TMSB4Y thymosin beta 4, Y-linked
TOP1P1 topoisomerase (DNA) I pseudogene 1
TRAM1L1 translocation associated membrane protein 1-like 1
TRIM32 tripartite motif containing 32
TRIM43 tripartite motif containing 43
TRIM61 tripartite motif containing 61
TSPO translocator protein (18kDa)
TTC33 tetratricopeptide repeat domain 33
TXN2 thioredoxin 2
TXNL4B thioredoxin-like 4B
UBQLN1 ubiquilin 1
UGP2 UDP-glucose pyrophosphorylase 2
UPK1B uroplakin 1B
USP10 ubiquitin specific peptidase 10
USP39 ubiquitin specific peptidase 39
UTS2 urotensin 2
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
VAMP8 vesicle-associated membrane protein 8
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDPCP WD repeat containing planar cell polarity effector
WDR61 WD repeat domain 61
WDR70 WD repeat domain 70
WDR72 WD repeat domain 72
WISP3 WNT1 inducible signaling pathway protein 3
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZFAND6 zinc finger, AN1-type domain 6
ZFP37 ZFP37 zinc finger protein
ZFY zinc finger protein, Y-linked
ZIK1 zinc finger protein interacting with K protein 1
ZNF131 zinc finger protein 131
ZNF134 zinc finger protein 134
ZNF155 zinc finger protein 155
ZNF189 zinc finger protein 189
ZNF211 zinc finger protein 211
ZNF222 zinc finger protein 222
ZNF223 zinc finger protein 223
ZNF230 zinc finger protein 230
ZNF233 zinc finger protein 233
ZNF28 zinc finger protein 28
ZNF285 zinc finger protein 285
ZNF320 zinc finger protein 320
ZNF321P zinc finger protein 321, pseudogene
ZNF350 zinc finger protein 350
ZNF404 zinc finger protein 404
ZNF415 zinc finger protein 415
ZNF468 zinc finger protein 468
ZNF484 zinc finger protein 484
ZNF518A zinc finger protein 518A
ZNF530 zinc finger protein 530
ZNF542P zinc finger protein 542, pseudogene
ZNF575 zinc finger protein 575
ZNF576 zinc finger protein 576
ZNF582 zinc finger protein 582
ZNF583 zinc finger protein 583
ZNF586 zinc finger protein 586
ZNF596 zinc finger protein 596
ZNF610 zinc finger protein 610
ZNF614 zinc finger protein 614
ZNF615 zinc finger protein 615
ZNF648 zinc finger protein 648
ZNF658 zinc finger protein 658
ZNF701 zinc finger protein 701
ZNF702P zinc finger protein 702, pseudogene
ZNF75A zinc finger protein 75a
ZNF772 zinc finger protein 772
ZNF788 zinc finger family member 788
ZNF808 zinc finger protein 808
ZNF816 zinc finger protein 816

low expression

Symbol Name
GGNBP2 gametogenetin binding protein 2
NF1 neurofibromin 1
NSRP1 nuclear speckle splicing regulatory protein 1
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
THADA thyroid adenoma associated