Lung adenocarcinoma_LUAD_TCGA-91-6849-01A-11R-1949-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung adenocarcinoma_LUAD (The Cancer Genome Atlas)
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Genes

442 genes with high or low expression in Lung adenocarcinoma_LUAD_TCGA-91-6849-01A-11R-1949-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABHD14A abhydrolase domain containing 14A
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACOT1 acyl-CoA thioesterase 1
ACOT2 acyl-CoA thioesterase 2
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTR3C ARP3 actin-related protein 3 homolog C (yeast)
ADI1 acireductone dioxygenase 1
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ADRA2C adrenoceptor alpha 2C
AGA aspartylglucosaminidase
AGPAT4-IT1 AGPAT4 intronic transcript 1
AKR1C1 aldo-keto reductase family 1, member C1
ALAS2 5'-aminolevulinate synthase 2
ALCAM activated leukocyte cell adhesion molecule
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALDH9A1 aldehyde dehydrogenase 9 family, member A1
ALOX15B arachidonate 15-lipoxygenase, type B
ALPL alkaline phosphatase, liver/bone/kidney
ANG angiogenin, ribonuclease, RNase A family, 5
ANKRD28 ankyrin repeat domain 28
ANKRD9 ankyrin repeat domain 9
ANO10 anoctamin 10
ANP32C acidic (leucine-rich) nuclear phosphoprotein 32 family, member C
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
APOD apolipoprotein D
AR androgen receptor
ARPIN actin-related protein 2/3 complex inhibitor
ARSA arylsulfatase A
ARSE arylsulfatase E (chondrodysplasia punctata 1)
AS3MT arsenite methyltransferase
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide
ATRAID all-trans retinoic acid-induced differentiation factor
ATXN7L1 ataxin 7-like 1
AVP arginine vasopressin
AVPI1 arginine vasopressin-induced 1
BHLHE40 basic helix-loop-helix family, member e40
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BRD7P3 bromodomain containing 7 pseudogene 3
BRDT bromodomain, testis-specific
BRSK2 BR serine/threonine kinase 2
BTD biotinidase
BTNL2 butyrophilin-like 2
C10ORF32 chromosome 10 open reading frame 32
C11ORF54 chromosome 11 open reading frame 54
C14ORF1 chromosome 14 open reading frame 1
C16ORF89 chromosome 16 open reading frame 89
C17ORF107 chromosome 17 open reading frame 107
C1ORF56 chromosome 1 open reading frame 56
C20ORF173 chromosome 20 open reading frame 173
C3ORF18 chromosome 3 open reading frame 18
C5AR1 complement component 5a receptor 1
C5AR2 complement component 5a receptor 2
C8ORF4 chromosome 8 open reading frame 4
C9ORF64 chromosome 9 open reading frame 64
CAB39L calcium binding protein 39-like
CABP5 calcium binding protein 5
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CBR1 carbonyl reductase 1
CBR3 carbonyl reductase 3
CCL16 chemokine (C-C motif) ligand 16
CCL22 chemokine (C-C motif) ligand 22
CCPG1 cell cycle progression 1
CCR3 chemokine (C-C motif) receptor 3
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2
CD300LB CD300 molecule-like family member b
CD38 CD38 molecule
CD63 CD63 molecule
CDH23 cadherin-related 23
CDNF cerebral dopamine neurotrophic factor
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CEP70 centrosomal protein 70kDa
CFI complement factor I
CH25H cholesterol 25-hydroxylase
CHI3L2 chitinase 3-like 2
CHID1 chitinase domain containing 1
CHIT1 chitinase 1 (chitotriosidase)
CHMP1B charged multivesicular body protein 1B
CLDN10 claudin 10
CLDND2 claudin domain containing 2
CLIC3 chloride intracellular channel 3
CLN5 ceroid-lipofuscinosis, neuronal 5
CLU clusterin
CNGA1 cyclic nucleotide gated channel alpha 1
CNTN3 contactin 3 (plasmacytoma associated)
CPQ carboxypeptidase Q
CREG1 cellular repressor of E1A-stimulated genes 1
CRELD1 cysteine-rich with EGF-like domains 1
CRELD2 cysteine-rich with EGF-like domains 2
CREM cAMP responsive element modulator
CRLF1 cytokine receptor-like factor 1
CRY2 cryptochrome circadian clock 2
CRYZ crystallin, zeta (quinone reductase)
CTNS cystinosin, lysosomal cystine transporter
CXCL16 chemokine (C-X-C motif) ligand 16
CYB5D2 cytochrome b5 domain containing 2
CYCSP52 cytochrome c, somatic pseudogene 52
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3
DCXR dicarbonyl/L-xylulose reductase
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae)
DESI2 desumoylating isopeptidase 2
DKFZP779M0652 uncharacterized DKFZp779M0652
DMGDH dimethylglycine dehydrogenase
DNASE1L1 deoxyribonuclease I-like 1
DOCK5 dedicator of cytokinesis 5
DUSP5 dual specificity phosphatase 5
EBPL emopamil binding protein-like
EGFL7 EGF-like-domain, multiple 7
EIF3IP1 eukaryotic translation initiation factor 3, subunit I pseudogene 1
ELL2 elongation factor, RNA polymerase II, 2
EMC10 ER membrane protein complex subunit 10
EML2 echinoderm microtubule associated protein like 2
ENOSF1 enolase superfamily member 1
EPDR1 ependymin related 1
EPHX2 epoxide hydrolase 2, cytoplasmic
ERGIC3 ERGIC and golgi 3
ERO1LB ERO1-like beta (S. cerevisiae)
ETFB electron-transfer-flavoprotein, beta polypeptide
F3 coagulation factor III (thromboplastin, tissue factor)
FAM149A family with sequence similarity 149, member A
FAM213A family with sequence similarity 213, member A
FAM46A family with sequence similarity 46, member A
FAM86B1 family with sequence similarity 86, member B1
FASN fatty acid synthase
FBXO2 F-box protein 2
FECH ferrochelatase
FFAR3 free fatty acid receptor 3
FKBP11 FK506 binding protein 11, 19 kDa
FKBP2 FK506 binding protein 2, 13kDa
FKBP5 FK506 binding protein 5
FLRT3 fibronectin leucine rich transmembrane protein 3
FOLR1 folate receptor 1 (adult)
FOXD4L5 forkhead box D4-like 5
FOXO1 forkhead box O1
FOXQ1 forkhead box Q1
FPGS folylpolyglutamate synthase
FUNDC2P2 FUN14 domain containing 2 pseudogene 2
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GCH1 GTP cyclohydrolase 1
GDF3 growth differentiation factor 3
GEM GTP binding protein overexpressed in skeletal muscle
GGN gametogenetin
GGT6 gamma-glutamyltransferase 6
GHDC GH3 domain containing
GKN2 gastrokine 2
GLB1 galactosidase, beta 1
GLIPR1L1 GLI pathogenesis-related 1 like 1
GLUL glutamate-ammonia ligase
GNB5 guanine nucleotide binding protein (G protein), beta 5
GNMT glycine N-methyltransferase
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit
GNRHR gonadotropin-releasing hormone receptor
GOLGA2P3Y golgin A2 pseudogene 3, Y-linked
GPR183 G protein-coupled receptor 183
GPR52 G protein-coupled receptor 52
GPRC5C G protein-coupled receptor, class C, group 5, member C
GREB1 growth regulation by estrogen in breast cancer 1
GYG2 glycogenin 2
HACD1 3-hydroxyacyl-CoA dehydratase 1
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HEXB hexosaminidase B (beta polypeptide)
HGD homogentisate 1,2-dioxygenase
HMGB3P1 high mobility group box 3 pseudogene 1
HMGN5 high mobility group nucleosome binding domain 5
HOMER2 homer scaffolding protein 2
HPN hepsin
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HUNK hormonally up-regulated Neu-associated kinase
IDNK idnK, gluconokinase homolog (E. coli)
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL17RE interleukin 17 receptor E
ING2 inhibitor of growth family, member 2
INO80C INO80 complex subunit C
IRS2 insulin receptor substrate 2
ITGA10 integrin, alpha 10
JADE1 jade family PHD finger 1
KATNBL1 katanin p80 subunit B-like 1
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KCTD3 potassium channel tetramerization domain containing 3
KIAA1109 KIAA1109
KIAA1324 KIAA1324
KLF15 Kruppel-like factor 15
KRTCAP2 keratinocyte associated protein 2
KRTCAP3 keratinocyte associated protein 3
LCN9 lipocalin 9
LMAN2 lectin, mannose-binding 2
LMF1 lipase maturation factor 1
LMO4 LIM domain only 4
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase
LNX2 ligand of numb-protein X 2
LOC100132831 A20-binding inhibitor of NF-kappaB activation 2 pseudogene
LOC643486
LOC649330
LONRF1 LON peptidase N-terminal domain and ring finger 1
LONRF3 LON peptidase N-terminal domain and ring finger 3
LPL lipoprotein lipase
LRP1B low density lipoprotein receptor-related protein 1B
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LY6D lymphocyte antigen 6 complex, locus D
LY9 lymphocyte antigen 9
MAN2B2 mannosidase, alpha, class 2B, member 2
MANF mesencephalic astrocyte-derived neurotrophic factor
MAOA monoamine oxidase A
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK11 mitogen-activated protein kinase 11
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MBD2 methyl-CpG binding domain protein 2
MCL1 myeloid cell leukemia 1
MDK midkine (neurite growth-promoting factor 2)
MED9 mediator complex subunit 9
MFSD7 major facilitator superfamily domain containing 7
MIR22HG MIR22 host gene
MMP9 matrix metallopeptidase 9
MOCS2 molybdenum cofactor synthesis 2
MORF4 mortality factor 4 (pseudogene)
MOSPD1 motile sperm domain containing 1
MSLN mesothelin
MSRA methionine sulfoxide reductase A
MTNR1A melatonin receptor 1A
MUC1 mucin 1, cell surface associated
NBEA neurobeachin
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NENF neudesin neurotrophic factor
NFIA nuclear factor I/A
NFIL3 nuclear factor, interleukin 3 regulated
NICN1 nicolin 1
NKIRAS1 NFKB inhibitor interacting Ras-like 1
NNMT nicotinamide N-methyltransferase
NOG noggin
NOTCH2NL notch 2 N-terminal like
NQO1 NAD(P)H dehydrogenase, quinone 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NTPCR nucleoside-triphosphatase, cancer-related
NUCB1 nucleobindin 1
NUCB2 nucleobindin 2
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
OCA2 oculocutaneous albinism II
OCSTAMP osteoclast stimulatory transmembrane protein
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3
OPRK1 opioid receptor, kappa 1
OR2B11 olfactory receptor, family 2, subfamily B, member 11
OR56B1 olfactory receptor, family 56, subfamily B, member 1
ORM2 orosomucoid 2
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PAX7 paired box 7
PBX3 pre-B-cell leukemia homeobox 3
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCCA propionyl CoA carboxylase, alpha polypeptide
PCDHGB2 protocadherin gamma subfamily B, 2
PCNT pericentrin
PCSK2 proprotein convertase subtilisin/kexin type 2
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFRL platelet-derived growth factor receptor-like
PDIA3 protein disulfide isomerase family A, member 3
PDIA3P1 protein disulfide isomerase family A, member 3 pseudogene 1
PELI1 pellino E3 ubiquitin protein ligase 1
PER1 period circadian clock 1
PEX11A peroxisomal biogenesis factor 11 alpha
PHF23 PHD finger protein 23
PHPT1 phosphohistidine phosphatase 1
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PIR pirin (iron-binding nuclear protein)
PLA2G10 phospholipase A2, group X
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLD3 phospholipase D family, member 3
PMM1 phosphomannomutase 1
PMVK phosphomevalonate kinase
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPIAL4D peptidylprolyl isomerase A (cyclophilin A)-like 4D
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPP1R3B protein phosphatase 1, regulatory subunit 3B
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PSEN2 presenilin 2
PTCHD4 patched domain containing 4
PTGR2 prostaglandin reductase 2
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PYROXD2 pyridine nucleotide-disulphide oxidoreductase domain 2
RAB27A RAB27A, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RANBP9 RAN binding protein 9
RAP1GAP RAP1 GTPase activating protein
RASD1 RAS, dexamethasone-induced 1
RASGEF1A RasGEF domain family, member 1A
RBMXL2 RNA binding motif protein, X-linked-like 2
REC114 REC114 meiotic recombination protein
REEP5 receptor accessory protein 5
RGS7 regulator of G-protein signaling 7
RHOB ras homolog family member B
RILP Rab interacting lysosomal protein
RND1 Rho family GTPase 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF167 ring finger protein 167
RPE65 retinal pigment epithelium-specific protein 65kDa
RPL29P2 ribosomal protein L29 pseudogene 2
SBF2 SET binding factor 2
SCGB2A1 secretoglobin, family 2A, member 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SDF2L1 stromal cell-derived factor 2-like 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SFN stratifin
SFTA2 surfactant associated 2
SFTPB surfactant protein B
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SHPK sedoheptulokinase
SIK1 salt-inducible kinase 1
SIL1 SIL1 nucleotide exchange factor
SIPA1L2 signal-induced proliferation-associated 1 like 2
SLC16A12 solute carrier family 16, member 12
SLC16A14 solute carrier family 16, member 14
SLC16A4 solute carrier family 16, member 4
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC25A18 solute carrier family 25 (glutamate carrier), member 18
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC26A9 solute carrier family 26 (anion exchanger), member 9
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SMAP2 small ArfGAP2
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMIM11 small integral membrane protein 11
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SMYD4 SET and MYND domain containing 4
SNORA21 small nucleolar RNA, H/ACA box 21
SNORA47 small nucleolar RNA, H/ACA box 47
SNX29 sorting nexin 29
SOCS3 suppressor of cytokine signaling 3
SORBS2 sorbin and SH3 domain containing 2
SOWAHC sosondowah ankyrin repeat domain family member C
SPAG7 sperm associated antigen 7
SPATA45 spermatogenesis associated 45
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae)
SPDYA speedy/RINGO cell cycle regulator family member A
SPDYE2 speedy/RINGO cell cycle regulator family member E2
SPDYE4 speedy/RINGO cell cycle regulator family member E4
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPPL2A signal peptide peptidase like 2A
SPRY4 sprouty homolog 4 (Drosophila)
SPTSSA serine palmitoyltransferase, small subunit A
SRP19 signal recognition particle 19kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK26 serine/threonine protein kinase 26
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SWI5 SWI5 recombination repair homolog (yeast)
SYBU syntabulin (syntaxin-interacting)
SYCP3 synaptonemal complex protein 3
TALDO1 transaldolase 1
TARP TCR gamma alternate reading frame protein
TCTA T-cell leukemia translocation altered
TCTN3 tectonic family member 3
TECTB tectorin beta
TEX38 testis expressed 38
THEM4 thioesterase superfamily member 4
TLR5 toll-like receptor 5
TMED3 transmembrane emp24 protein transport domain containing 3
TMEM108 transmembrane protein 108
TMEM114 transmembrane protein 114
TMEM59 transmembrane protein 59
TMEM59L transmembrane protein 59-like
TMEM89 transmembrane protein 89
TMEM9 transmembrane protein 9
TMEM91 transmembrane protein 91
TMPRSS6 transmembrane protease, serine 6
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TOB1 transducer of ERBB2, 1
TOB2 transducer of ERBB2, 2
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like
TPI1P3 triosephosphate isomerase 1 pseudogene 3
TRAPPC1 trafficking protein particle complex 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TSC22D3 TSC22 domain family, member 3
TSPAN1 tetraspanin 1
TSPAN7 tetraspanin 7
TSPEAR-AS2 TSPEAR antisense RNA 2
TUBB7P tubulin, beta 7, pseudogene
TUBBP5 tubulin, beta pseudogene 5
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP27X ubiquitin specific peptidase 27, X-linked
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VKORC1 vitamin K epoxide reductase complex, subunit 1
WDR81 WD repeat domain 81
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C
ZC3H7A zinc finger CCCH-type containing 7A
ZDHHC9 zinc finger, DHHC-type containing 9
ZFAND5 zinc finger, AN1-type domain 5
ZFP36 ZFP36 ring finger protein
ZNF281 zinc finger protein 281
ZNF330 zinc finger protein 330
ZNF331 zinc finger protein 331
ZNF645 zinc finger protein 645

low expression

Symbol Name
C11ORF57 chromosome 11 open reading frame 57
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
TRAFD1 TRAF-type zinc finger domain containing 1
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF20 zinc finger protein 20
ZNF416 zinc finger protein 416
ZNF543 zinc finger protein 543
ZNF562 zinc finger protein 562
ZNF71 zinc finger protein 71
ZNF776 zinc finger protein 776
ZNF823 zinc finger protein 823
ZNF845 zinc finger protein 845