Lung adenocarcinoma_LUAD_TCGA-69-7978-01A-11R-2187-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung adenocarcinoma_LUAD (The Cancer Genome Atlas)
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Genes

403 genes with high or low expression in Lung adenocarcinoma_LUAD_TCGA-69-7978-01A-11R-2187-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACOT11 acyl-CoA thioesterase 11
ACSM4 acyl-CoA synthetase medium-chain family member 4
ADAM21P1 ADAM metallopeptidase domain 21 pseudogene 1
ADAM22 ADAM metallopeptidase domain 22
ADAP2 ArfGAP with dual PH domains 2
ADGRE2 adhesion G protein-coupled receptor E2
ADRB3 adrenoceptor beta 3
AGRN agrin
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALPK1 alpha-kinase 1
ANKIB1 ankyrin repeat and IBR domain containing 1
ANO6 anoctamin 6
APLF aprataxin and PNKP like factor
APOA4 apolipoprotein A-IV
ARHGAP20 Rho GTPase activating protein 20
ARHGEF35 Rho guanine nucleotide exchange factor (GEF) 35
ARL10 ADP-ribosylation factor-like 10
ASPH aspartate beta-hydroxylase
ATP10A ATPase, class V, type 10A
ATP11C ATPase, class VI, type 11C
ATP8B4 ATPase, class I, type 8B, member 4
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BBX bobby sox homolog (Drosophila)
BCL9L B-cell CLL/lymphoma 9-like
BEST1 bestrophin 1
BMP2K BMP2 inducible kinase
BRD4 bromodomain containing 4
BTBD8 BTB (POZ) domain containing 8
C12ORF43 chromosome 12 open reading frame 43
C16ORF72 chromosome 16 open reading frame 72
C16ORF82 chromosome 16 open reading frame 82
C17ORF51 chromosome 17 open reading frame 51
C1R complement component 1, r subcomponent
C2CD4C C2 calcium-dependent domain containing 4C
C2ORF16 chromosome 2 open reading frame 16
C2ORF61 chromosome 2 open reading frame 61
C3ORF79 chromosome 3 open reading frame 79
C5ORF58 chromosome 5 open reading frame 58
C6ORF223 chromosome 6 open reading frame 223
C7ORF72 chromosome 7 open reading frame 72
C9ORF129 chromosome 9 open reading frame 129
CALU calumenin
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CASP5 caspase 5, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCDC83 coiled-coil domain containing 83
CCDC88A coiled-coil domain containing 88A
CCL13 chemokine (C-C motif) ligand 13
CCL8 chemokine (C-C motif) ligand 8
CCR8 chemokine (C-C motif) receptor 8
CD163L1 CD163 molecule-like 1
CD209 CD209 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD84 CD84 molecule
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CEP290 centrosomal protein 290kDa
CFB complement factor B
CFLAR CASP8 and FADD-like apoptosis regulator
CHERP calcium homeostasis endoplasmic reticulum protein
CHIT1 chitinase 1 (chitotriosidase)
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CLEC5A C-type lectin domain family 5, member A
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CNOT3 CCR4-NOT transcription complex, subunit 3
CNOT4 CCR4-NOT transcription complex, subunit 4
COLGALT1 collagen beta(1-O)galactosyltransferase 1
CORO1C coronin, actin binding protein, 1C
CRLF2 cytokine receptor-like factor 2
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CST7 cystatin F (leukocystatin)
CTSB cathepsin B
CTSC cathepsin C
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYSLTR2 cysteinyl leukotriene receptor 2
DAW1 dynein assembly factor with WDR repeat domains 1
DCBLD1 discoidin, CUB and LCCL domain containing 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DPRXP4 divergent-paired related homeobox pseudogene 4
DSC2 desmocollin 2
DSE dermatan sulfate epimerase
DSP desmoplakin
DTX2 deltex 2, E3 ubiquitin ligase
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DTX3L deltex 3 like, E3 ubiquitin ligase
EDN2 endothelin 2
EIF5A2 eukaryotic translation initiation factor 5A2
EME2 essential meiotic structure-specific endonuclease subunit 2
EP400 E1A binding protein p400
EPHA1 EPH receptor A1
EPHB2 EPH receptor B2
ERCC6L2 excision repair cross-complementation group 6-like 2
ERO1L ERO1-like (S. cerevisiae)
FAM129B family with sequence similarity 129, member B
FAM134C family with sequence similarity 134, member C
FAM168A family with sequence similarity 168, member A
FAM205A family with sequence similarity 205, member A
FAM206A family with sequence similarity 206, member A
FAM225B family with sequence similarity 225, member B (non-protein coding)
FAM83B family with sequence similarity 83, member B
FAM90A7P putative protein FAM90A7
FAXDC2 fatty acid hydroxylase domain containing 2
FBXL13 F-box and leucine-rich repeat protein 13
FBXO32 F-box protein 32
FBXO41 F-box protein 41
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FDPSP2 farnesyl diphosphate synthase pseudogene 2
FGF11 fibroblast growth factor 11
FICD FIC domain containing
FITM2 fat storage-inducing transmembrane protein 2
FIZ1 FLT3-interacting zinc finger 1
FKTN fukutin
FLJ37201 tigger transposable element derived 2 pseudogene
FLT1 fms-related tyrosine kinase 1
FMO1 flavin containing monooxygenase 1
FOXP3 forkhead box P3
FSCN2 fascin actin-bundling protein 2, retinal
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
FYN FYN proto-oncogene, Src family tyrosine kinase
GATSL2 GATS protein-like 2
GBP1 guanylate binding protein 1, interferon-inducible
GCC1 GRIP and coiled-coil domain containing 1
GDF5 growth differentiation factor 5
GEMIN5 gem (nuclear organelle) associated protein 5
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLS glutaminase
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GOLIM4 golgi integral membrane protein 4
GPATCH11 G patch domain containing 11
GPATCH2L G patch domain containing 2-like
GPC6 glypican 6
GPR15 G protein-coupled receptor 15
GPR158 G protein-coupled receptor 158
GPR174 G protein-coupled receptor 174
GPR84 G protein-coupled receptor 84
GPRIN1 G protein regulated inducer of neurite outgrowth 1
GREB1L growth regulation by estrogen in breast cancer-like
GRM5 glutamate receptor, metabotropic 5
HDX highly divergent homeobox
HELB helicase (DNA) B
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HHIPL2 HHIP-like 2
HIST1H3J histone cluster 1, H3j
HIST2H2BA histone cluster 2, H2ba (pseudogene)
HIST2H3D histone cluster 2, H3d
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-B major histocompatibility complex, class I, B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HSPA1L heat shock 70kDa protein 1-like
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
HVCN1 hydrogen voltage gated channel 1
IFITM4P interferon induced transmembrane protein 4 pseudogene
IFNK interferon, kappa
IGF2R insulin-like growth factor 2 receptor
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL12RB2 interleukin 12 receptor, beta 2
IL15RA interleukin 15 receptor, alpha
IL20RB interleukin 20 receptor beta
IL21R interleukin 21 receptor
IL2RA interleukin 2 receptor, alpha
IL9R interleukin 9 receptor
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IRS1 insulin receptor substrate 1
ISM2 isthmin 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB7 integrin, beta 7
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
IVL involucrin
JAK1 Janus kinase 1
JAK3 Janus kinase 3
KIAA0226 KIAA0226
KIAA1107 KIAA1107
KIAA1147 KIAA1147
KIAA1217 KIAA1217
KIRREL kin of IRRE like (Drosophila)
KLC3 kinesin light chain 3
KLHDC10 kelch domain containing 10
LAMB3 laminin, beta 3
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LHFPL2 lipoma HMGIC fusion partner-like 2
LHFPL4 lipoma HMGIC fusion partner-like 4
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LIMK1 LIM domain kinase 1
LINC00158 long intergenic non-protein coding RNA 158
LMLN leishmanolysin-like (metallopeptidase M8 family)
LNPEP leucyl/cystinyl aminopeptidase
LOC100131496 uncharacterized LOC100131496
LOX lysyl oxidase
LRFN1 leucine rich repeat and fibronectin type III domain containing 1
LRRC42 leucine rich repeat containing 42
LRRN4 leucine rich repeat neuronal 4
LSM11 LSM11, U7 small nuclear RNA associated
LTN1 listerin E3 ubiquitin protein ligase 1
LY75 lymphocyte antigen 75
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP1S microtubule-associated protein 1S
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAST3 microtubule associated serine/threonine kinase 3
MBOAT7 membrane bound O-acyltransferase domain containing 7
MEGF8 multiple EGF-like-domains 8
MET MET proto-oncogene, receptor tyrosine kinase
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MGC45800
MMP12 matrix metallopeptidase 12
MPZL3 myelin protein zero-like 3
MSN moesin
MYADML myeloid-associated differentiation marker-like (pseudogene)
MYF6 myogenic factor 6 (herculin)
MYO1G myosin IG
NABP1 nucleic acid binding protein 1
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAIP NLR family, apoptosis inhibitory protein
NCS1 neuronal calcium sensor 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NGEF neuronal guanine nucleotide exchange factor
NLRP2 NLR family, pyrin domain containing 2
NMT2 N-myristoyltransferase 2
NOMO1 NODAL modulator 1
NOTCH3 notch 3
NRP2 neuropilin 2
NTAN1 N-terminal asparagine amidase
NUB1 negative regulator of ubiquitin-like proteins 1
NUMBL numb homolog (Drosophila)-like
OGFR opioid growth factor receptor
OR12D3 olfactory receptor, family 12, subfamily D, member 3
OR13G1 olfactory receptor, family 13, subfamily G, member 1
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene)
OR1J2 olfactory receptor, family 1, subfamily J, member 2
OR1J4 olfactory receptor, family 1, subfamily J, member 4
OR2L2 olfactory receptor, family 2, subfamily L, member 2
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
OR2T5 olfactory receptor, family 2, subfamily T, member 5
OR4D1 olfactory receptor, family 4, subfamily D, member 1
OR52B4 olfactory receptor, family 52, subfamily B, member 4 (gene/pseudogene)
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAPLN papilin, proteoglycan-like sulfated glycoprotein
PCDHGB3 protocadherin gamma subfamily B, 3
PCDHGB6 protocadherin gamma subfamily B, 6
PCNX pecanex homolog (Drosophila)
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDIA5 protein disulfide isomerase family A, member 5
PFN4 profilin family, member 4
PHLDB2 pleckstrin homology-like domain, family B, member 2
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PLBD2 phospholipase B domain containing 2
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCXD2 phosphatidylinositol-specific phospholipase C, X domain containing 2
PLD5 phospholipase D family, member 5
PLEKHN1 pleckstrin homology domain containing, family N member 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLXNA1 plexin A1
PLXNC1 plexin C1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POM121 POM121 transmembrane nucleoporin
POM121C POM121 transmembrane nucleoporin C
PON1 paraoxonase 1
PORCN porcupine homolog (Drosophila)
POU2F2 POU class 2 homeobox 2
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R12C protein phosphatase 1, regulatory subunit 12C
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PPP6R1 protein phosphatase 6, regulatory subunit 1
PRDM4 PR domain containing 4
PRO0628 uncharacterized LOC29053
PRR23C proline rich 23C
PRRC2A proline-rich coiled-coil 2A
PRSS37 protease, serine, 37
PRSS42 protease, serine, 42
PTBP3 polypyrimidine tract binding protein 3
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPRF protein tyrosine phosphatase, receptor type, F
PTPRH protein tyrosine phosphatase, receptor type, H
PWRN2 Prader-Willi region non-protein coding RNA 2
QSOX2 quiescin Q6 sulfhydryl oxidase 2
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RASA2 RAS p21 protein activator 2
RASAL2 RAS protein activator like 2
RC3H2 ring finger and CCCH-type domains 2
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RDH13 retinol dehydrogenase 13 (all-trans/9-cis)
RHBDD1 rhomboid domain containing 1
RHO rhodopsin
RIMS3 regulating synaptic membrane exocytosis 3
RNF149 ring finger protein 149
RNF24 ring finger protein 24
SAMD9L sterile alpha motif domain containing 9-like
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SERINC3 serine incorporator 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SH2D2A SH2 domain containing 2A
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene)
SIGLEC15 sialic acid binding Ig-like lectin 15
SIMC1 SUMO-interacting motifs containing 1
SIN3B SIN3 transcription regulator family member B
SIRPG signal-regulatory protein gamma
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLAMF8 SLAM family member 8
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC25A43 solute carrier family 25, member 43
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC35E1 solute carrier family 35, member E1
SLC35E2 solute carrier family 35, member E2
SLC43A3 solute carrier family 43, member 3
SLC7A5P2 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SLFN12L schlafen family member 12-like
SLX4IP SLX4 interacting protein
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMN1 survival of motor neuron 1, telomeric
SOX30 SRY (sex determining region Y)-box 30
SPATA2 spermatogenesis associated 2
SPIN2A spindlin family, member 2A
SPRED3 sprouty-related, EVH1 domain containing 3
SSTR3 somatostatin receptor 3
STAB2 stabilin 2
STARD6 StAR-related lipid transfer (START) domain containing 6
STAT5B signal transducer and activator of transcription 5B
STEAP1 six transmembrane epithelial antigen of the prostate 1
STEAP2 STEAP family member 2, metalloreductase
STK35 serine/threonine kinase 35
TAOK3 TAO kinase 3
TAS2R3 taste receptor, type 2, member 3
TAS2R31 taste receptor, type 2, member 31
TAS2R4 taste receptor, type 2, member 4
TAS2R5 taste receptor, type 2, member 5
TBC1D3P2 TBC1 domain family, member 3 pseudogene 2
TCAF1 TRPM8 channel-associated factor 1
TESPA1 thymocyte expressed, positive selection associated 1
TGFBI transforming growth factor, beta-induced, 68kDa
TICAM2 toll-like receptor adaptor molecule 2
TIGIT T cell immunoreceptor with Ig and ITIM domains
TLDC2 TBC/LysM-associated domain containing 2
TM9SF4 transmembrane 9 superfamily protein member 4
TMEM106A transmembrane protein 106A
TMEM185B transmembrane protein 185B
TMEM86B transmembrane protein 86B
TNNT1 troponin T type 1 (skeletal, slow)
TNPO3 transportin 3
TPCN1 two pore segment channel 1
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
TRABD2A TraB domain containing 2A
TRAF1 TNF receptor-associated factor 1
TRIM56 tripartite motif containing 56
TSC22D2 TSC22 domain family, member 2
TSNAX-DISC1 TSNAX-DISC1 readthrough (NMD candidate)
TTBK2 tau tubulin kinase 2
TTPAL tocopherol (alpha) transfer protein-like
UBE2S ubiquitin-conjugating enzyme E2S
UBE3B ubiquitin protein ligase E3B
UBQLN2 ubiquilin 2
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP24 ubiquitin specific peptidase 24
VSX1 visual system homeobox 1
VWA7 von Willebrand factor A domain containing 7
WFDC13 WAP four-disulfide core domain 13
WIPF1 WAS/WASL interacting protein family, member 1
WIZ widely interspaced zinc finger motifs
WNK1 WNK lysine deficient protein kinase 1
WNT10A wingless-type MMTV integration site family, member 10A
XRN1 5'-3' exoribonuclease 1
ZBED2 zinc finger, BED-type containing 2
ZBTB20 zinc finger and BTB domain containing 20
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF135 zinc finger protein 135
ZNF142 zinc finger protein 142
ZNF280C zinc finger protein 280C
ZNF430 zinc finger protein 430
ZNF524 zinc finger protein 524
ZNF526 zinc finger protein 526
ZNF532 zinc finger protein 532
ZNF579 zinc finger protein 579
ZNF628 zinc finger protein 628
ZNF699 zinc finger protein 699
ZNF784 zinc finger protein 784
ZNF880 zinc finger protein 880
ZNFX1 zinc finger, NFX1-type containing 1
ZSCAN22 zinc finger and SCAN domain containing 22

low expression

Symbol Name
RNF10 ring finger protein 10