Lung adenocarcinoma_LUAD_TCGA-50-5939-01A-11R-1628-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung adenocarcinoma_LUAD (The Cancer Genome Atlas)
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Genes

375 genes with high or low expression in Lung adenocarcinoma_LUAD_TCGA-50-5939-01A-11R-1628-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABLIM2 actin binding LIM protein family, member 2
ACKR3 atypical chemokine receptor 3
ACRV1 acrosomal vesicle protein 1
ACTR3C ARP3 actin-related protein 3 homolog C (yeast)
ADAM17 ADAM metallopeptidase domain 17
ADAM21 ADAM metallopeptidase domain 21
ADAM21P1 ADAM metallopeptidase domain 21 pseudogene 1
ADAM8 ADAM metallopeptidase domain 8
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADCY3 adenylate cyclase 3
ADGRG3 adhesion G protein-coupled receptor G3
ADGRG6 adhesion G protein-coupled receptor G6
ADSSL1 adenylosuccinate synthase like 1
AFAP1 actin filament associated protein 1
AGBL5 ATP/GTP binding protein-like 5
AGFG1 ArfGAP with FG repeats 1
AGRN agrin
AHNAK2 AHNAK nucleoprotein 2
AIG1 androgen-induced 1
AIM1 absent in melanoma 1
ALDOC aldolase C, fructose-bisphosphate
AMOTL2 angiomotin like 2
ANTXR2 anthrax toxin receptor 2
ANXA8 annexin A8
AP1AR adaptor-related protein complex 1 associated regulatory protein
AREG amphiregulin
ARHGAP21 Rho GTPase activating protein 21
ARHGAP23 Rho GTPase activating protein 23
ARHGEF35 Rho guanine nucleotide exchange factor (GEF) 35
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARL13A ADP-ribosylation factor-like 13A
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ASPH aspartate beta-hydroxylase
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BCAR3 breast cancer anti-estrogen resistance 3
BCL9L B-cell CLL/lymphoma 9-like
BIRC3 baculoviral IAP repeat containing 3
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
BTBD1 BTB (POZ) domain containing 1
BZW1 basic leucine zipper and W2 domains 1
C11ORF63 chromosome 11 open reading frame 63
C15ORF39 chromosome 15 open reading frame 39
C16ORF74 chromosome 16 open reading frame 74
C16ORF78 chromosome 16 open reading frame 78
C17ORF51 chromosome 17 open reading frame 51
C1QTNF6 C1q and tumor necrosis factor related protein 6
C20ORF173 chromosome 20 open reading frame 173
C9ORF129 chromosome 9 open reading frame 129
C9ORF69 chromosome 9 open reading frame 69
C9ORF84 chromosome 9 open reading frame 84
CARD6 caspase recruitment domain family, member 6
CASP4 caspase 4, apoptosis-related cysteine peptidase
CBX5 chromobox homolog 5
CD109 CD109 molecule
CD276 CD276 molecule
CD99 CD99 molecule
CDA cytidine deaminase
CDC27 cell division cycle 27
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDCP1 CUB domain containing protein 1
CDK18 cyclin-dependent kinase 18
CEP85L centrosomal protein 85kDa-like
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CHML choroideremia-like (Rab escort protein 2)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLEC3A C-type lectin domain family 3, member A
CLMP CXADR-like membrane protein
COL4A5 collagen, type IV, alpha 5
COL4A6 collagen, type IV, alpha 6
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
COL8A1 collagen, type VIII, alpha 1
CP ceruloplasmin (ferroxidase)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSNK1E casein kinase 1, epsilon
CTAGE4 CTAGE family, member 4
CTAGE9 CTAGE family, member 9
CTBP2 C-terminal binding protein 2
DBIL5P diazepam binding inhibitor-like 5, pseudogene
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DIAPH1 diaphanous-related formin 1
DLG5 discs, large homolog 5 (Drosophila)
DMGDH dimethylglycine dehydrogenase
DNAJB8 DnaJ (Hsp40) homolog, subfamily B, member 8
DSE dermatan sulfate epimerase
DSG2 desmoglein 2
DVL1 dishevelled segment polarity protein 1
EFHD2 EF-hand domain family, member D2
EGFR epidermal growth factor receptor
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF4B eukaryotic translation initiation factor 4B
ELK1 ELK1, member of ETS oncogene family
EMC1 ER membrane protein complex subunit 1
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2
EPHA2 EPH receptor A2
EPPK1 epiplakin 1
ERCC6L2 excision repair cross-complementation group 6-like 2
ERO1L ERO1-like (S. cerevisiae)
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EVA1C eva-1 homolog C (C. elegans)
EXOC4 exocyst complex component 4
F12 coagulation factor XII (Hageman factor)
F3 coagulation factor III (thromboplastin, tissue factor)
FAM189B family with sequence similarity 189, member B
FAM73A family with sequence similarity 73, member A
FAM83A family with sequence similarity 83, member A
FAM83G family with sequence similarity 83, member G
FBXO2 F-box protein 2
FBXO45 F-box protein 45
FICD FIC domain containing
FKTN fukutin
FLII flightless I homolog (Drosophila)
FLNA filamin A, alpha
FLNB filamin B, beta
FLNC filamin C, gamma
FLOT2 flotillin 2
FNDC3B fibronectin type III domain containing 3B
FOSL1 FOS-like antigen 1
FRMD8 FERM domain containing 8
FRRS1 ferric-chelate reductase 1
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
GALC galactosylceramidase
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GBE1 glucan (1,4-alpha-), branching enzyme 1
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GJB3 gap junction protein, beta 3, 31kDa
GPR107 G protein-coupled receptor 107
GPR176 G protein-coupled receptor 176
GUSB glucuronidase, beta
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HACD1 3-hydroxyacyl-CoA dehydratase 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HPCAL1 hippocalcin-like 1
HRK harakiri, BCL2 interacting protein
IFNA8 interferon, alpha 8
IGFBP6 insulin-like growth factor binding protein 6
IL15RA interleukin 15 receptor, alpha
IL1RL1 interleukin 1 receptor-like 1
IL20RB interleukin 20 receptor beta
INF2 inverted formin, FH2 and WH2 domain containing
INSL3 insulin-like 3 (Leydig cell)
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRAK3 interleukin-1 receptor-associated kinase 3
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JKAMP JNK1/MAPK8-associated membrane protein
KIAA1045 KIAA1045
KLF17 Kruppel-like factor 17
KRT7 keratin 7, type II
KRT81 keratin 81, type II
KRT85 keratin 85, type II
KYNU kynureninase
LAMA5 laminin, alpha 5
LAMB3 laminin, beta 3
LAMC2 laminin, gamma 2
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LARP1 La ribonucleoprotein domain family, member 1
LBP lipopolysaccharide binding protein
LINC00111 long intergenic non-protein coding RNA 111
LINC00313 long intergenic non-protein coding RNA 313
LINC00346 long intergenic non-protein coding RNA 346
LMAN1 lectin, mannose-binding, 1
LMLN leishmanolysin-like (metallopeptidase M8 family)
LPAR5 lysophosphatidic acid receptor 5
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRIF1 ligand dependent nuclear receptor interacting factor 1
LRP1 low density lipoprotein receptor-related protein 1
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC61 leucine rich repeat containing 61
LRRK1 leucine-rich repeat kinase 1
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LYZL1 lysozyme-like 1
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MARVELD1 MARVEL domain containing 1
MCF2L2 MCF.2 cell line derived transforming sequence-like 2
MESDC1 mesoderm development candidate 1
MFAP3 microfibrillar-associated protein 3
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MID2 midline 2
MINK1 misshapen-like kinase 1
MIP major intrinsic protein of lens fiber
MLXIP MLX interacting protein
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MPZL3 myelin protein zero-like 3
MSANTD3 Myb/SANT-like DNA-binding domain containing 3
MT1X metallothionein 1X
MT2A metallothionein 2A
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MXD1 MAX dimerization protein 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NDFIP2 Nedd4 family interacting protein 2
NEO1 neogenin 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NLGN4Y neuroligin 4, Y-linked
NMBR neuromedin B receptor
NPC1 Niemann-Pick disease, type C1
OAF OAF homolog (Drosophila)
OR13H1 olfactory receptor, family 13, subfamily H, member 1
OR2A7 olfactory receptor, family 2, subfamily A, member 7
OR51L1 olfactory receptor, family 51, subfamily L, member 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PANX1 pannexin 1
PANX2 pannexin 2
PAPLN papilin, proteoglycan-like sulfated glycoprotein
PAQR7 progestin and adipoQ receptor family member VII
PARP16 poly (ADP-ribose) polymerase family, member 16
PARP6 poly (ADP-ribose) polymerase family, member 6
PCDHA11 protocadherin alpha 11
PCDHA5 protocadherin alpha 5
PCDHGB1 protocadherin gamma subfamily B, 1
PCDHGB4 protocadherin gamma subfamily B, 4
PCDHGB5 protocadherin gamma subfamily B, 5
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PGM1 phosphoglucomutase 1
PGM2 phosphoglucomutase 2
PHC2 polyhomeotic homolog 2 (Drosophila)
PHF10 PHD finger protein 10
PHLDB2 pleckstrin homology-like domain, family B, member 2
PIEZO1 piezo-type mechanosensitive ion channel component 1
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2
PITX1 paired-like homeodomain 1
PKP2 plakophilin 2
PLBD2 phospholipase B domain containing 2
PLCD3 phospholipase C, delta 3
PLEC plectin
PLK2 polo-like kinase 2
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
POPDC3 popeye domain containing 3
PORCN porcupine homolog (Drosophila)
PPL periplakin
PPP1R26 protein phosphatase 1, regulatory subunit 26
PPP1R3G protein phosphatase 1, regulatory subunit 3G
PRDM8 PR domain containing 8
PROSER2 proline and serine rich 2
PRSS23 protease, serine, 23
PTGR1 prostaglandin reductase 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPRM protein tyrosine phosphatase, receptor type, M
PXN paxillin
QSOX2 quiescin Q6 sulfhydryl oxidase 2
RAB31 RAB31, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAD23B RAD23 homolog B (S. cerevisiae)
RAET1G retinoic acid early transcript 1G
RARG retinoic acid receptor, gamma
RASA3 RAS p21 protein activator 3
RASGEF1A RasGEF domain family, member 1A
RC3H2 ring finger and CCCH-type domains 2
RGS20 regulator of G-protein signaling 20
RHBDD1 rhomboid domain containing 1
RHOF ras homolog family member F (in filopodia)
RND3 Rho family GTPase 3
RSPH3 radial spoke 3 homolog (Chlamydomonas)
RXRA retinoid X receptor, alpha
SEC61G Sec61 gamma subunit
SEPT9 septin 9
SERINC3 serine incorporator 3
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SH2D5 SH2 domain containing 5
SH3RF3 SH3 domain containing ring finger 3
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene)
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC35F2 solute carrier family 35, member F2
SLC46A1 solute carrier family 46 (folate transporter), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SLN sarcolipin
SMAD3 SMAD family member 3
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SNAI1 snail family zinc finger 1
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SNORA46 small nucleolar RNA, H/ACA box 46
SNX29 sorting nexin 29
SOD2 superoxide dismutase 2, mitochondrial
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SSH1 slingshot protein phosphatase 1
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STC1 stanniocalcin 1
SUSD3 sushi domain containing 3
SYN1 synapsin I
TAPBP TAP binding protein (tapasin)
TBC1D14 TBC1 domain family, member 14
TCF23 transcription factor 23
TCTN2 tectonic family member 2
TDRD9 tudor domain containing 9
TGFB2 transforming growth factor, beta 2
TGM2 transglutaminase 2
THSD4 thrombospondin, type I, domain containing 4
TIMP1 TIMP metallopeptidase inhibitor 1
TMEM164 transmembrane protein 164
TMEM171 transmembrane protein 171
TMEM181 transmembrane protein 181
TMEM184B transmembrane protein 184B
TMEM194B transmembrane protein 194B
TMEM30B transmembrane protein 30B
TMEM44 transmembrane protein 44
TMEM45A transmembrane protein 45A
TMEM95 transmembrane protein 95
TMIE transmembrane inner ear
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNIP1 TNFAIP3 interacting protein 1
TNIP3 TNFAIP3 interacting protein 3
TNPO1 transportin 1
TNS4 tensin 4
TOR4A torsin family 4, member A
TPBG trophoblast glycoprotein
TRAF3 TNF receptor-associated factor 3
TRAF3IP2 TRAF3 interacting protein 2
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
TRIM29 tripartite motif containing 29
TRIM32 tripartite motif containing 32
TRIM7 tripartite motif containing 7
TTC22 tetratricopeptide repeat domain 22
TUBB6 tubulin, beta 6 class V
TUBGCP2 tubulin, gamma complex associated protein 2
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
UBE2H ubiquitin-conjugating enzyme E2H
UBN1 ubinuclein 1
UNC5A unc-5 homolog A (C. elegans)
VANGL1 VANGL planar cell polarity protein 1
VAV2 vav 2 guanine nucleotide exchange factor
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
VSTM5 V-set and transmembrane domain containing 5
WASF2 WAS protein family, member 2
WDR36 WD repeat domain 36
ZBED6CL ZBED6 C-terminal like
ZBTB38 zinc finger and BTB domain containing 38
ZC3H12C zinc finger CCCH-type containing 12C
ZFY zinc finger protein, Y-linked
ZNF740 zinc finger protein 740
ZNF770 zinc finger protein 770

low expression

Symbol Name
GALT galactose-1-phosphate uridylyltransferase
ZNF155 zinc finger protein 155