Lung adenocarcinoma_LUAD_TCGA-05-4410-01A-21R-1858-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung adenocarcinoma_LUAD (The Cancer Genome Atlas)
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Genes

350 genes with high or low expression in Lung adenocarcinoma_LUAD_TCGA-05-4410-01A-21R-1858-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABHD15 abhydrolase domain containing 15
ACACA acetyl-CoA carboxylase alpha
ACPP acid phosphatase, prostate
ADM2 adrenomedullin 2
ADRBK1 adrenergic, beta, receptor kinase 1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGK acylglycerol kinase
AGMAT agmatine ureohydrolase (agmatinase)
AHR aryl hydrocarbon receptor
AHRR aryl-hydrocarbon receptor repressor
AK3 adenylate kinase 3
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKRD36BP1 ankyrin repeat domain 36B pseudogene 1
ANKRD44 ankyrin repeat domain 44
ANTXR2 anthrax toxin receptor 2
ARHGAP12 Rho GTPase activating protein 12
ARHGAP42 Rho GTPase activating protein 42
ARHGAP8 Rho GTPase activating protein 8
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATG2A autophagy related 2A
ATP13A4 ATPase type 13A4
ATXN7 ataxin 7
B3GAT1 beta-1,3-glucuronyltransferase 1
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BRD1 bromodomain containing 1
BRPF3 bromodomain and PHD finger containing, 3
C11ORF54 chromosome 11 open reading frame 54
C11ORF94 chromosome 11 open reading frame 94
C20ORF144 chromosome 20 open reading frame 144
C9ORF41 chromosome 9 open reading frame 41
CAMK1D calcium/calmodulin-dependent protein kinase ID
CAPN5 calpain 5
CCDC112 coiled-coil domain containing 112
CCDC134 coiled-coil domain containing 134
CCDC27 coiled-coil domain containing 27
CCDC88C coiled-coil domain containing 88C
CCNYL1 cyclin Y-like 1
CD27 CD27 molecule
CDC37L1 cell division cycle 37-like 1
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CEP152 centrosomal protein 152kDa
CEP19 centrosomal protein 19kDa
CHAD chondroadherin
CKM creatine kinase, muscle
CLCN2 chloride channel, voltage-sensitive 2
CMTM4 CKLF-like MARVEL transmembrane domain containing 4
CMYA5 cardiomyopathy associated 5
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CORO2A coronin, actin binding protein, 2A
CRAT carnitine O-acetyltransferase
CTAGE9 CTAGE family, member 9
CTNNBIP1 catenin, beta interacting protein 1
CTRC chymotrypsin C (caldecrin)
CTTN cortactin
DCAF10 DDB1 and CUL4 associated factor 10
DCAF12 DDB1 and CUL4 associated factor 12
DDAH1 dimethylarginine dimethylaminohydrolase 1
DENND1B DENN/MADD domain containing 1B
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DNAJB8 DnaJ (Hsp40) homolog, subfamily B, member 8
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21
DOCK8 dedicator of cytokinesis 8
DPP4 dipeptidyl-peptidase 4
DSCAML1 Down syndrome cell adhesion molecule like 1
DUPD1 dual specificity phosphatase and pro isomerase domain containing 1
DUSP5P1 dual specificity phosphatase 5 pseudogene 1
ECHDC3 enoyl CoA hydratase domain containing 3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2
EN2 engrailed homeobox 2
ENDOD1 endonuclease domain containing 1
EP300 E1A binding protein p300
EPDR1 ependymin related 1
FAM114A1 family with sequence similarity 114, member A1
FAM117B family with sequence similarity 117, member B
FAM129A family with sequence similarity 129, member A
FAM222B family with sequence similarity 222, member B
FAM225A family with sequence similarity 225, member A (non-protein coding)
FAM225B family with sequence similarity 225, member B (non-protein coding)
FAM46C family with sequence similarity 46, member C
FAM86C1 family with sequence similarity 86, member C1
FAM86DP family with sequence similarity 86, member D, pseudogene
FLVCR1-AS1 FLVCR1 antisense RNA 1 (head to head)
FMN1 formin 1
FNBP1 formin binding protein 1
FREM1 FRAS1 related extracellular matrix 1
FRK fyn-related Src family tyrosine kinase
FUT2 fucosyltransferase 2 (secretor status included)
FYCO1 FYVE and coiled-coil domain containing 1
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GAREM GRB2 associated, regulator of MAPK1
GBA2 glucosidase, beta (bile acid) 2
GCAT glycine C-acetyltransferase
GCC1 GRIP and coiled-coil domain containing 1
GDE1 glycerophosphodiester phosphodiesterase 1
GFM1 G elongation factor, mitochondrial 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLB1L2 galactosidase, beta 1-like 2
GLCCI1 glucocorticoid induced 1
GLIS3 GLIS family zinc finger 3
GOLIM4 golgi integral membrane protein 4
GPR107 G protein-coupled receptor 107
GPR15 G protein-coupled receptor 15
GPR31 G protein-coupled receptor 31
GSK3A glycogen synthase kinase 3 alpha
GTF2IRD1 GTF2I repeat domain containing 1
HIBADH 3-hydroxyisobutyrate dehydrogenase
HIPK2 homeodomain interacting protein kinase 2
HIST2H3D histone cluster 2, H3d
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
HLA-E major histocompatibility complex, class I, E
HLA-H major histocompatibility complex, class I, H (pseudogene)
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HOOK1 hook microtubule-tethering protein 1
HOXA10 homeobox A10
HOXA3 homeobox A3
HOXA6 homeobox A6
HOXD1 homeobox D1
HOXD3 homeobox D3
HSDL2 hydroxysteroid dehydrogenase like 2
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
ICMT isoprenylcysteine carboxyl methyltransferase
IFNK interferon, kappa
IFT74 intraflagellar transport 74
IKZF3 IKAROS family zinc finger 3 (Aiolos)
ILDR1 immunoglobulin-like domain containing receptor 1
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IQCF6 IQ motif containing F6
IRF7 interferon regulatory factor 7
ISPD isoprenoid synthase domain containing
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNK7 potassium channel, two pore domain subfamily K, member 7
KDM2A lysine (K)-specific demethylase 2A
KDM7A lysine (K)-specific demethylase 7A
KIAA0100 KIAA0100
KIAA0226 KIAA0226
KIAA0930 KIAA0930
KIAA1257 KIAA1257
KIAA1522 KIAA1522
KIAA1804 mixed lineage kinase 4
KIAA1958 KIAA1958
KIF16B kinesin family member 16B
KLHDC10 kelch domain containing 10
KLHL11 kelch-like family member 11
KLHL12 kelch-like family member 12
KLHL2 kelch-like family member 2
KLHL23 kelch-like family member 23
KLHL5 kelch-like family member 5
KLRG2 killer cell lectin-like receptor subfamily G, member 2
KRTAP4-2 keratin associated protein 4-2
LAD1 ladinin 1
LAX1 lymphocyte transmembrane adaptor 1
LDOC1L leucine zipper, down-regulated in cancer 1-like
LIAS lipoic acid synthetase
LIMK1 LIM domain kinase 1
LINC01558 long intergenic non-protein coding RNA 1558
LMLN leishmanolysin-like (metallopeptidase M8 family)
LOC100129034 uncharacterized LOC100129034
LOC100133669 uncharacterized LOC100133669
LOC283070
LOC340017 uncharacterized LOC340017
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRP5 low density lipoprotein receptor-related protein 5
LY75 lymphocyte antigen 75
LYPD5 LY6/PLAUR domain containing 5
MANBA mannosidase, beta A, lysosomal
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MFSD9 major facilitator superfamily domain containing 9
MGC15885 uncharacterized protein MGC15885
MIOX myo-inositol oxygenase
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYO6 myosin VI
N4BP2 NEDD4 binding protein 2
NCMAP noncompact myelin associated protein
NEU3 sialidase 3 (membrane sialidase)
NOL4L nucleolar protein 4-like
NOL6 nucleolar protein 6 (RNA-associated)
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPAS2 neuronal PAS domain protein 2
NUMBL numb homolog (Drosophila)-like
NUP50 nucleoporin 50kDa
NUTM1 NUT midline carcinoma, family member 1
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OMP olfactory marker protein
OR2A14 olfactory receptor, family 2, subfamily A, member 14
OR2A25 olfactory receptor, family 2, subfamily A, member 25
OR5B21 olfactory receptor, family 5, subfamily B, member 21
OR6S1 olfactory receptor, family 6, subfamily S, member 1
ORAI2 ORAI calcium release-activated calcium modulator 2
OSBP oxysterol binding protein
OVOL1 ovo-like zinc finger 1
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PARD3 par-3 family cell polarity regulator
PARM1 prostate androgen-regulated mucin-like protein 1
PARP14 poly (ADP-ribose) polymerase family, member 14
PCNXL3 pecanex-like 3 (Drosophila)
PDCD2L programmed cell death 2-like
PDIA2 protein disulfide isomerase family A, member 2
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PDS5A PDS5 cohesin associated factor A
PER3 period circadian clock 3
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PLA2G2C phospholipase A2, group IIC
PLAA phospholipase A2-activating protein
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PLXNA1 plexin A1
PLXND1 plexin D1
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
POM121C POM121 transmembrane nucleoporin C
PON3 paraoxonase 3
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2
PPARA peroxisome proliferator-activated receptor alpha
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP6R2 protein phosphatase 6, regulatory subunit 2
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PROCA1 protein interacting with cyclin A1
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PVR poliovirus receptor
RAB11FIP4 RAB11 family interacting protein 4 (class II)
RAB19 RAB19, member RAS oncogene family
RAB38 RAB38, member RAS oncogene family
RAB43 RAB43, member RAS oncogene family
RABL3 RAB, member of RAS oncogene family-like 3
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RASEF RAS and EF-hand domain containing
RBBP8 retinoblastoma binding protein 8
RBM47 RNA binding motif protein 47
RCAN2 regulator of calcineurin 2
RCAN3 RCAN family member 3
RCL1 RNA terminal phosphate cyclase-like 1
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHBDD2 rhomboid domain containing 2
RHOXF1 Rhox homeobox family, member 1
RIMS3 regulating synaptic membrane exocytosis 3
RNF115 ring finger protein 115
RNF133 ring finger protein 133
RNF135 ring finger protein 135
RNF38 ring finger protein 38
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RSBN1L round spermatid basic protein 1-like
RTN4RL2 reticulon 4 receptor-like 2
SBF1 SET binding factor 1
SCARNA9L small Cajal body-specific RNA 9-like
SCRN1 secernin 1
SCYL1 SCY1-like 1 (S. cerevisiae)
SERHL serine hydrolase-like (pseudogene)
SERTAD4 SERTA domain containing 4
SETD2 SET domain containing 2
SHB Src homology 2 domain containing adaptor protein B
SIDT1 SID1 transmembrane family, member 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SIGMAR1 sigma non-opioid intracellular receptor 1
SIK3 SIK family kinase 3
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLAIN1 SLAIN motif family, member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SLC37A3 solute carrier family 37, member 3
SLC41A2 solute carrier family 41 (magnesium transporter), member 2
SMIM14 small integral membrane protein 14
SNX15 sorting nexin 15
SNX27 sorting nexin family member 27
SPDYE3 speedy/RINGO cell cycle regulator family member E3
SPTBN2 spectrin, beta, non-erythrocytic 2
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SREBF2 sterol regulatory element binding transcription factor 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STK35 serine/threonine kinase 35
STRADB STE20-related kinase adaptor beta
STX3 syntaxin 3
SYT12 synaptotagmin XII
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAS2R50 taste receptor, type 2, member 50
TATDN2 TatD DNase domain containing 2
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TBC1D16 TBC1 domain family, member 16
TCF20 transcription factor 20 (AR1)
TEF thyrotrophic embryonic factor
TGFB1 transforming growth factor, beta 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM184B transmembrane protein 184B
TMEM41A transmembrane protein 41A
TMIGD1 transmembrane and immunoglobulin domain containing 1
TNIK TRAF2 and NCK interacting kinase
TNNI1 troponin I type 1 (skeletal, slow)
TOP1 topoisomerase (DNA) I
TOP1P1 topoisomerase (DNA) I pseudogene 1
TRIM25 tripartite motif containing 25
TRIM69 tripartite motif containing 69
TRIOBP TRIO and F-actin binding protein
TSPAN16 tetraspanin 16
TTC39B tetratricopeptide repeat domain 39B
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
TXNIP thioredoxin interacting protein
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UBE2K ubiquitin-conjugating enzyme E2K
UBE3C ubiquitin protein ligase E3C
UNC13B unc-13 homolog B (C. elegans)
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
USP25 ubiquitin specific peptidase 25
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1
VPS26B vacuolar protein sorting 26 homolog B (S. pombe)
VSTM2L V-set and transmembrane domain containing 2 like
VSX1 visual system homeobox 1
WDR26 WD repeat domain 26
XRRA1 X-ray radiation resistance associated 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZBED4 zinc finger, BED-type containing 4
ZC3H7B zinc finger CCCH-type containing 7B
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFAND4 zinc finger, AN1-type domain 4
ZFP91 ZFP91 zinc finger protein
ZMYND11 zinc finger, MYND-type containing 11
ZNF148 zinc finger protein 148
ZNF280B zinc finger protein 280B
ZNF283 zinc finger protein 283
ZNF295-AS1 ZNF295 antisense RNA 1
ZNF341 zinc finger protein 341
ZNF628 zinc finger protein 628
ZNF790 zinc finger protein 790
ZNF827 zinc finger protein 827
ZNF835 zinc finger protein 835
ZSCAN31 zinc finger and SCAN domain containing 31

low expression

Symbol Name
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
PCBP1 poly(rC) binding protein 1
RNF8 ring finger protein 8, E3 ubiquitin protein ligase