Lung Diseases, Interstitial Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D017563
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Genes

99 genes/proteins associated with the disease Lung Diseases, Interstitial from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
SOD2 superoxide dismutase 2, mitochondrial 2.88009
IL6 interleukin 6 1.74561
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.71255
TNF tumor necrosis factor 1.67441
IFNG interferon, gamma 1.66382
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.65358
BCL2 B-cell CLL/lymphoma 2 1.62268
PARP1 poly (ADP-ribose) polymerase 1 1.58959
CAT catalase 1.58303
MPO myeloperoxidase 1.54159
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.47813
IL10 interleukin 10 1.46986
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.4612
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.43157
DDIT3 DNA-damage-inducible transcript 3 1.4202
IL4 interleukin 4 1.40568
TP53 tumor protein p53 1.38669
BAX BCL2-associated X protein 1.37303
BIRC5 baculoviral IAP repeat containing 5 1.37189
H2AFX H2A histone family, member X 1.34782
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.34401
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.33731
CCL2 chemokine (C-C motif) ligand 2 1.32993
CXCL8 chemokine (C-X-C motif) ligand 8 1.32518
FAS Fas cell surface death receptor 1.32162
RAD51 RAD51 recombinase 1.32074
IL2 interleukin 2 1.31566
ATF5 activating transcription factor 5 1.30543
TGFB1 transforming growth factor, beta 1 1.30543
F3 coagulation factor III (thromboplastin, tissue factor) 1.27782
VEGFA vascular endothelial growth factor A 1.27751
JUN jun proto-oncogene 1.2772
XBP1 X-box binding protein 1 1.27657
IGFBP3 insulin-like growth factor binding protein 3 1.23328
GSTP1 glutathione S-transferase pi 1 1.23233
ICAM1 intercellular adhesion molecule 1 1.22469
VCAM1 vascular cell adhesion molecule 1 1.21599
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.20784
MBP myelin basic protein 1.19999
PCNA proliferating cell nuclear antigen 1.19966
MMP9 matrix metallopeptidase 9 1.19966
IL1B interleukin 1, beta 1.19737
CLU clusterin 1.19737
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.19672
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.19509
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.19445
EGR1 early growth response 1 1.19213
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.19146
DUSP1 dual specificity phosphatase 1 1.18193
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.17794
MAPK1 mitogen-activated protein kinase 1 1.169
CXCL10 chemokine (C-X-C motif) ligand 10 1.16833
ITGB5 integrin, beta 5 1.15695
CCNA2 cyclin A2 1.15627
EGFR epidermal growth factor receptor 1.15425
NOS2 nitric oxide synthase 2, inducible 1.14919
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.1485
RRM2 ribonucleotide reductase M2 1.14541
DUSP10 dual specificity phosphatase 10 1.14507
ATF3 activating transcription factor 3 1.14268
CCND3 cyclin D3 1.14234
ALAS2 5'-aminolevulinate synthase 2 1.13929
HSPA1B heat shock 70kDa protein 1B 1.13484
BRCA1 breast cancer 1, early onset 1.13484
ERBB2 erb-b2 receptor tyrosine kinase 2 1.12048
C3 complement component 3 1.11081
BCL2L1 BCL2-like 1 1.11081
MAGED1 melanoma antigen family D1 1.10069
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.10033
GFAP glial fibrillary acidic protein 1.09083
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.08797
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.08091
RB1 retinoblastoma 1 1.07234
GSTT1 glutathione S-transferase theta 1 1.06771
GSTM1 glutathione S-transferase mu 1 1.06625
CYCS cytochrome c, somatic 1.06552
MAPK3 mitogen-activated protein kinase 3 1.06333
APP amyloid beta (A4) precursor protein 1.0608
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.06044
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.05461
ENC1 ectodermal-neural cortex 1 (with BTB domain) 1.05386
IL5 interleukin 5 1.05237
TOP2A topoisomerase (DNA) II alpha 170kDa 1.05237
ACVR1C activin A receptor, type IC 1.05163
CDC14B cell division cycle 14B 1.05126
KLF4 Kruppel-like factor 4 (gut) 1.04794
CXCR6 chemokine (C-X-C motif) receptor 6 1.04088
HMOX1 heme oxygenase 1 1.04088
NRP1 neuropilin 1 1.03827
NAMPT nicotinamide phosphoribosyltransferase 1.03827
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.03493
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.03493
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.03456
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.02336
CCND1 cyclin D1 1.02188
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.01814
POR P450 (cytochrome) oxidoreductase 1.01701
EGR2 early growth response 2 1.01474
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.01062