Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25Z-01A-11R-A16W-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Liver hepatocellular carcinoma_LIHC (The Cancer Genome Atlas)
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341 genes with high or low expression in Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25Z-01A-11R-A16W-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AARS alanyl-tRNA synthetase
AARSD1 alanyl-tRNA synthetase domain containing 1
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ACBD4 acyl-CoA binding domain containing 4
ACMSD aminocarboxymuconate semialdehyde decarboxylase
ACOX3 acyl-CoA oxidase 3, pristanoyl
ACP1 acid phosphatase 1, soluble
ADAM30 ADAM metallopeptidase domain 30
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C4 aldo-keto reductase family 1, member C4
AKTIP AKT interacting protein
ALDOC aldolase C, fructose-bisphosphate
ALKBH6 alkB, alkylation repair homolog 6 (E. coli)
AMZ2 archaelysin family metallopeptidase 2
ARID5A AT rich interactive domain 5A (MRF1-like)
ARL17A ADP-ribosylation factor-like 17A
ASCC2 activating signal cointegrator 1 complex subunit 2
ASCL3 achaete-scute family bHLH transcription factor 3
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG3 autophagy related 3
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
BCAS2 breast carcinoma amplified sequence 2
BCCIP BRCA2 and CDKN1A interacting protein
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
BECN1 beclin 1, autophagy related
BIN3 bridging integrator 3
BOLA3 bolA family member 3
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BSDC1 BSD domain containing 1
C11ORF65 chromosome 11 open reading frame 65
C11ORF74 chromosome 11 open reading frame 74
C1D C1D nuclear receptor corepressor
C1ORF189 chromosome 1 open reading frame 189
C2ORF47 chromosome 2 open reading frame 47
C2ORF49 chromosome 2 open reading frame 49
C4A complement component 4A (Rodgers blood group)
C4BPB complement component 4 binding protein, beta
C5 complement component 5
C9ORF43 chromosome 9 open reading frame 43
CBWD3 COBW domain containing 3
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC148 coiled-coil domain containing 148
CCDC25 coiled-coil domain containing 25
CCL16 chemokine (C-C motif) ligand 16
CCNH cyclin H
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC26 cell division cycle 26
CDK18 cyclin-dependent kinase 18
CEACAM20 carcinoembryonic antigen-related cell adhesion molecule 20
CFHR3 complement factor H-related 3
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4
CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5
CHD1L chromodomain helicase DNA binding protein 1-like
CHMP7 charged multivesicular body protein 7
CHURC1 churchill domain containing 1
CIAO1 cytosolic iron-sulfur assembly component 1
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CLNS1A chloride channel, nucleotide-sensitive, 1A
CLTCL1 clathrin, heavy chain-like 1
CLU clusterin
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COA5 cytochrome c oxidase assembly factor 5
COMT catechol-O-methyltransferase
COPRS coordinator of PRMT5, differentiation stimulator
COPS8 COP9 signalosome subunit 8
COQ10B coenzyme Q10 homolog B (S. cerevisiae)
COQ9 coenzyme Q9
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
CPM carboxypeptidase M
CPN1 carboxypeptidase N, polypeptide 1
CRELD1 cysteine-rich with EGF-like domains 1
CWC15 CWC15 spliceosome-associated protein
CXORF58 chromosome X open reading frame 58
CYB5R2 cytochrome b5 reductase 2
CYCS cytochrome c, somatic
DACH2 dachshund family transcription factor 2
DAPK3 death-associated protein kinase 3
DARS aspartyl-tRNA synthetase
DCTN6 dynactin 6
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DEFB1 defensin, beta 1
DESI1 desumoylating isopeptidase 1
DHRS11 dehydrogenase/reductase (SDR family) member 11
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
DISP2 dispatched homolog 2 (Drosophila)
DNAH6 dynein, axonemal, heavy chain 6
DNPEP aspartyl aminopeptidase
DNTTIP1 deoxynucleotidyltransferase, terminal, interacting protein 1
DTNA dystrobrevin, alpha
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
DUSP3 dual specificity phosphatase 3
DUSP8 dual specificity phosphatase 8
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
EGLN1 egl-9 family hypoxia-inducible factor 1
EIF1 eukaryotic translation initiation factor 1
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
EIF3I eukaryotic translation initiation factor 3, subunit I
EIF4A3 eukaryotic translation initiation factor 4A3
ELP3 elongator acetyltransferase complex subunit 3
ENOSF1 enolase superfamily member 1
ERICH1 glutamate-rich 1
ESD esterase D
ESPNL espin-like
FAM192A family with sequence similarity 192, member A
FAM229B family with sequence similarity 229, member B
FBXO16 F-box protein 16
FBXO25 F-box protein 25
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDXACB1 ferredoxin-fold anticodon binding domain containing 1
FGF12 fibroblast growth factor 12
FGL1 fibrinogen-like 1
FH fumarate hydratase
FNDC4 fibronectin type III domain containing 4
FOXR1 forkhead box R1
GAA glucosidase, alpha; acid
GCKR glucokinase (hexokinase 4) regulator
GHDC GH3 domain containing
GMPPA GDP-mannose pyrophosphorylase A
GPKOW G patch domain and KOW motifs
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa
HLA-L major histocompatibility complex, class I, L (pseudogene)
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific
HMGB3P1 high mobility group box 3 pseudogene 1
HMOX2 heme oxygenase 2
HPCAL1 hippocalcin-like 1
HPR haptoglobin-related protein
HS1BP3 HCLS1 binding protein 3
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HSPE1 heat shock 10kDa protein 1
HTRA2 HtrA serine peptidase 2
ICA1 islet cell autoantigen 1, 69kDa
ICAM2 intercellular adhesion molecule 2
IFI35 interferon-induced protein 35
IFITM4P interferon induced transmembrane protein 4 pseudogene
IFT43 intraflagellar transport 43
IGFBP4 insulin-like growth factor binding protein 4
IL10RB interleukin 10 receptor, beta
IL1R2 interleukin 1 receptor, type II
ILK integrin-linked kinase
IMP4 IMP4, U3 small nucleolar ribonucleoprotein
IQCD IQ motif containing D
ISCA2 iron-sulfur cluster assembly 2
IWS1 IWS1 homolog (S. cerevisiae)
JUP junction plakoglobin
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LBP lipopolysaccharide binding protein
LCN6 lipocalin 6
LEAP2 liver expressed antimicrobial peptide 2
LINC00240 long intergenic non-protein coding RNA 240
LINC00303 long intergenic non-protein coding RNA 303
LINC00467 long intergenic non-protein coding RNA 467
LMNTD2 lamin tail domain containing 2
LOC100133985 uncharacterized LOC100133985
LRRC46 leucine rich repeat containing 46
LRRC6 leucine rich repeat containing 6
LSM1 LSM1, U6 small nuclear RNA associated
LYAR Ly1 antibody reactive
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MARCH2 membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
MCEE methylmalonyl CoA epimerase
MDH1 malate dehydrogenase 1, NAD (soluble)
MEAF6 MYST/Esa1-associated factor 6
MED28 mediator complex subunit 28
MED9 mediator complex subunit 9
METAP1D methionyl aminopeptidase type 1D (mitochondrial)
METTL5 methyltransferase like 5
MIEN1 migration and invasion enhancer 1
MLX MLX, MAX dimerization protein
MORN2 MORN repeat containing 2
MRFAP1 Morf4 family associated protein 1
MRPL18 mitochondrial ribosomal protein L18
MRPL33 mitochondrial ribosomal protein L33
MRPL35 mitochondrial ribosomal protein L35
MRPL40 mitochondrial ribosomal protein L40
MRPS22 mitochondrial ribosomal protein S22
MRPS5 mitochondrial ribosomal protein S5
MRPS9 mitochondrial ribosomal protein S9
MSH4 mutS homolog 4
MTIF2 mitochondrial translational initiation factor 2
MTO1 mitochondrial tRNA translation optimization 1
MTRF1 mitochondrial translational release factor 1
MYO7B myosin VIIB
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NFU1 NFU1 iron-sulfur cluster scaffold
NIFK nucleolar protein interacting with the FHA domain of MKI67
NKAIN2 Na+/K+ transporting ATPase interacting 2
NMT1 N-myristoyltransferase 1
NOP14 NOP14 nucleolar protein
NOS2 nitric oxide synthase 2, inducible
NPM2 nucleophosmin/nucleoplasmin 2
NRG1 neuregulin 1
NUBP1 nucleotide binding protein 1
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OTOL1 otolin 1
PACRGL PARK2 co-regulated-like
PCBP1 poly(rC) binding protein 1
PCGF1 polycomb group ring finger 1
PCM1 pericentriolar material 1
PEX10 peroxisomal biogenesis factor 10
PEX12 peroxisomal biogenesis factor 12
PHF7 PHD finger protein 7
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase
PID1 phosphotyrosine interaction domain containing 1
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PIWIL2 piwi-like RNA-mediated gene silencing 2
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
PLGLA plasminogen-like A (pseudogene)
PLGLB2 plasminogen-like B2
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PLSCR2 phospholipid scramblase 2
PNO1 partner of NOB1 homolog (S. cerevisiae)
PNPO pyridoxamine 5'-phosphate oxidase
PNPT1 polyribonucleotide nucleotidyltransferase 1
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POLR1A polymerase (RNA) I polypeptide A, 194kDa
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PPP4R4 protein phosphatase 4, regulatory subunit 4
PQLC1 PQ loop repeat containing 1
PRAMEF1 PRAME family member 1
PRAMEF10 PRAME family member 10
PRAMEF11 PRAME family member 11
PRAMEF17 PRAME family member 17
PRAMEF2 PRAME family member 2
PRAMEF4 PRAME family member 4
PRAMEF5 PRAME family member 5
PRAMEF6 PRAME family member 6
PRAMEF9 PRAME family member 9
PRMT5 protein arginine methyltransferase 5
PROSC proline synthetase co-transcribed homolog (bacterial)
PRR19 proline rich 19
PRR34 proline rich 34
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTGR2 prostaglandin reductase 2
PVR poliovirus receptor
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
QSOX2 quiescin Q6 sulfhydryl oxidase 2
R3HCC1 R3H domain and coiled-coil containing 1
RAB1A RAB1A, member RAS oncogene family
RAB32 RAB32, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RABEPK Rab9 effector protein with kelch motifs
RBKS ribokinase
RITA1 RBPJ interacting and tubulin associated 1
RNF181 ring finger protein 181
RPF1 ribosome production factor 1 homolog (S. cerevisiae)
RPF2 ribosome production factor 2 homolog (S. cerevisiae)
RPGR retinitis pigmentosa GTPase regulator
RPRD1B regulation of nuclear pre-mRNA domain containing 1B
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae)
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
RTN4IP1 reticulon 4 interacting protein 1
SCLY selenocysteine lyase
SCRN3 secernin 3
SDS serine dehydratase
SDSL serine dehydratase-like
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SH3BGR SH3 domain binding glutamate-rich protein
SLAIN1 SLAIN motif family, member 1
SLAMF9 SLAM family member 9
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35B1 solute carrier family 35, member B1
SLC35G2 solute carrier family 35, member G2
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SNX17 sorting nexin 17
SPATA2L spermatogenesis associated 2-like
SPATA6L spermatogenesis associated 6-like
SPINK9 serine peptidase inhibitor, Kazal type 9
SPRYD7 SPRY domain containing 7
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAMBP STAM binding protein
STK16 serine/threonine kinase 16
STK39 serine threonine kinase 39
STX11 syntaxin 11
STX12 syntaxin 12
SUCLG1 succinate-CoA ligase, alpha subunit
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SUSD3 sushi domain containing 3
SYCE1 synaptonemal complex central element protein 1
TCP10L t-complex 10-like
TGM2 transglutaminase 2
TGM3 transglutaminase 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM126A transmembrane protein 126A
TMEM176A transmembrane protein 176A
TMEM198 transmembrane protein 198
TMEM199 transmembrane protein 199
TMEM218 transmembrane protein 218
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TOM1L1 target of myb1 (chicken)-like 1
TPRKB TP53RK binding protein
TRABD2A TraB domain containing 2A
TRAF4 TNF receptor-associated factor 4
TRIM55 tripartite motif containing 55
TTC27 tetratricopeptide repeat domain 27
TTC9B tetratricopeptide repeat domain 9B
TTLL13P tubulin tyrosine ligase-like family member 13, pseudogene
TUBG1 tubulin, gamma 1
TXNDC9 thioredoxin domain containing 9
TYW5 tRNA-yW synthesizing protein 5
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
USP2 ubiquitin specific peptidase 2
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae)
WBP2 WW domain binding protein 2
WDR1 WD repeat domain 1
WDR12 WD repeat domain 12
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZBTB8OS zinc finger and BTB domain containing 8 opposite strand
ZCRB1 zinc finger CCHC-type and RNA binding motif 1
ZFAT zinc finger and AT hook domain containing
ZFYVE19 zinc finger, FYVE domain containing 19
ZNF165 zinc finger protein 165
ZNF513 zinc finger protein 513
ZNF584 zinc finger protein 584
ZNF684 zinc finger protein 684

low expression

Symbol Name
DDB1 damage-specific DNA binding protein 1, 127kDa
INTS5 integrator complex subunit 5
KDM5A lysine (K)-specific demethylase 5A
USP10 ubiquitin specific peptidase 10
USP9X ubiquitin specific peptidase 9, X-linked