Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11D-01A-11R-A131-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Liver hepatocellular carcinoma_LIHC (The Cancer Genome Atlas)
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Genes

346 genes with high or low expression in Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11D-01A-11R-A131-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACOX1 acyl-CoA oxidase 1, palmitoyl
ACP2 acid phosphatase 2, lysosomal
ADAMTSL4 ADAMTS-like 4
ADGRG2 adhesion G protein-coupled receptor G2
AGBL1 ATP/GTP binding protein-like 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHNAK AHNAK nucleoprotein
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANGPT2 angiopoietin 2
ANO6 anoctamin 6
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
ANPEP alanyl (membrane) aminopeptidase
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APLN apelin
APLP2 amyloid beta (A4) precursor-like protein 2
APOB apolipoprotein B
AQP4-AS1 AQP4 antisense RNA 1
AQP8 aquaporin 8
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASCC2 activating signal cointegrator 1 complex subunit 2
ATG10 autophagy related 10
ATP13A4 ATPase type 13A4
ATXN7L1 ataxin 7-like 1
AWAT2 acyl-CoA wax alcohol acyltransferase 2
BCAS1 breast carcinoma amplified sequence 1
BDKRB2 bradykinin receptor B2
BHMT betaine--homocysteine S-methyltransferase
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1
C15ORF48 chromosome 15 open reading frame 48
C2ORF61 chromosome 2 open reading frame 61
C7ORF43 chromosome 7 open reading frame 43
CALD1 caldesmon 1
CASKIN2 CASK interacting protein 2
CAST calpastatin
CCDC116 coiled-coil domain containing 116
CCDC125 coiled-coil domain containing 125
CCDC177 coiled-coil domain containing 177
CCND3 cyclin D3
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CES2 carboxylesterase 2
CES4A carboxylesterase 4A
CGN cingulin
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
CLDN15 claudin 15
CLDN16 claudin 16
CLPTM1L CLPTM1-like
CLU clusterin
CNOT4 CCR4-NOT transcription complex, subunit 4
CNTFR ciliary neurotrophic factor receptor
COL18A1 collagen, type XVIII, alpha 1
CPB2 carboxypeptidase B2 (plasma)
CPEB4 cytoplasmic polyadenylation element binding protein 4
CPT1A carnitine palmitoyltransferase 1A (liver)
CRHR2 corticotropin releasing hormone receptor 2
CSMD1 CUB and Sushi multiple domains 1
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTSD cathepsin D
CUX1 cut-like homeobox 1
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
CYB5R3 cytochrome b5 reductase 3
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
DEPDC5 DEP domain containing 5
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHCR24 24-dehydrocholesterol reductase
DHFRL1 dihydrofolate reductase-like 1
DIAPH1 diaphanous-related formin 1
DIRC1 disrupted in renal carcinoma 1
DISP2 dispatched homolog 2 (Drosophila)
DOPEY2 dopey family member 2
DPCR1 diffuse panbronchiolitis critical region 1
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1
EIF4H eukaryotic translation initiation factor 4H
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPHA1 EPH receptor A1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
ERLIN2 ER lipid raft associated 2
ESYT1 extended synaptotagmin-like protein 1
F12 coagulation factor XII (Hageman factor)
F2 coagulation factor II (thrombin)
FAHD2B fumarylacetoacetate hydrolase domain containing 2B
FAM174A family with sequence similarity 174, member A
FAM184A family with sequence similarity 184, member A
FBN3 fibrillin 3
FBXO38 F-box protein 38
FER1L6 fer-1-like family member 6
FGFR2 fibroblast growth factor receptor 2
FMR1NB fragile X mental retardation 1 neighbor
FRY furry homolog (Drosophila)
FURIN furin (paired basic amino acid cleaving enzyme)
FZD3 frizzled class receptor 3
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GALC galactosylceramidase
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GANAB glucosidase, alpha; neutral AB
GCKR glucokinase (hexokinase 4) regulator
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1
GGCX gamma-glutamyl carboxylase
GLDC glycine dehydrogenase (decarboxylating)
GLDN gliomedin
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR155 G protein-coupled receptor 155
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GUCA1A guanylate cyclase activator 1A (retina)
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HAL histidine ammonia-lyase
HDAC10 histone deacetylase 10
HEXB hexosaminidase B (beta polypeptide)
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HYDIN HYDIN, axonemal central pair apparatus protein
IFNK interferon, kappa
IGIP IgA-inducing protein
IL10RB interleukin 10 receptor, beta
IL1F10 interleukin 1 family, member 10 (theta)
IL1RL2 interleukin 1 receptor-like 2
IL3 interleukin 3
ILDR2 immunoglobulin-like domain containing receptor 2
INF2 inverted formin, FH2 and WH2 domain containing
INHBC inhibin, beta C
INSIG1 insulin induced gene 1
IQGAP2 IQ motif containing GTPase activating protein 2
ITGA1 integrin, alpha 1
ITGA7 integrin, alpha 7
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
ITPK1 inositol-tetrakisphosphate 1-kinase
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KDM4E lysine (K)-specific demethylase 4E
KIAA0825 KIAA0825
KIAA1161 KIAA1161
KIAA1467 KIAA1467
KIF17 kinesin family member 17
KLHDC10 kelch domain containing 10
KLHL34 kelch-like family member 34
KRT20 keratin 20, type I
LAMP1 lysosomal-associated membrane protein 1
LARGE like-glycosyltransferase
LDHAL6B lactate dehydrogenase A-like 6B
LGALS3 lectin, galactoside-binding, soluble, 3
LINC00271 long intergenic non-protein coding RNA 271
LIPH lipase, member H
LMBRD1 LMBR1 domain containing 1
LMF2 lipase maturation factor 2
LONP2 lon peptidase 2, peroxisomal
LPPR2 lipid phosphate phosphatase-related protein type 2
LRRC31 leucine rich repeat containing 31
LRWD1 leucine-rich repeats and WD repeat domain containing 1
LTBP3 latent transforming growth factor beta binding protein 3
MAN2A2 mannosidase, alpha, class 2A, member 2
MAN2B2 mannosidase, alpha, class 2B, member 2
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MCC mutated in colorectal cancers
MEF2D myocyte enhancer factor 2D
METTL7B methyltransferase like 7B
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MGLL monoglyceride lipase
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP28 matrix metallopeptidase 28
MPZL3 myelin protein zero-like 3
MSH4 mutS homolog 4
MUC21 mucin 21, cell surface associated
MYH14 myosin, heavy chain 14, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
NAGA N-acetylgalactosaminidase, alpha-
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D
NAT8 N-acetyltransferase 8 (GCN5-related, putative)
NAV2 neuron navigator 2
NDFIP1 Nedd4 family interacting protein 1
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NGEF neuronal guanine nucleotide exchange factor
NLN neurolysin (metallopeptidase M3 family)
NOS2 nitric oxide synthase 2, inducible
NRG2 neuregulin 2
NRG4 neuregulin 4
NRTN neurturin
NT5E 5'-nucleotidase, ecto (CD73)
NUDCD3 NudC domain containing 3
NUDT12 nudix (nucleoside diphosphate linked moiety X)-type motif 12
NXT2 nuclear transport factor 2-like export factor 2
OLFM2 olfactomedin 2
OOEP oocyte expressed protein
OR13D1 olfactory receptor, family 13, subfamily D, member 1
OR52E6 olfactory receptor, family 52, subfamily E, member 6
ORC5 origin recognition complex, subunit 5
ORM2 orosomucoid 2
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PANX2 pannexin 2
PCDHA13 protocadherin alpha 13
PCDHB14 protocadherin beta 14
PCDHGA2 protocadherin gamma subfamily A, 2
PCSK4 proprotein convertase subtilisin/kexin type 4
PEX11A peroxisomal biogenesis factor 11 alpha
PIGM phosphatidylinositol glycan anchor biosynthesis, class M
PIGR polymeric immunoglobulin receptor
PITPNB phosphatidylinositol transfer protein, beta
PLEK2 pleckstrin 2
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PLXDC2 plexin domain containing 2
PLXNA2 plexin A2
PLXNC1 plexin C1
PNKD paroxysmal nonkinesigenic dyskinesia
PNPLA2 patatin-like phospholipase domain containing 2
POF1B premature ovarian failure, 1B
POR P450 (cytochrome) oxidoreductase
PP2D1 protein phosphatase 2C-like domain containing 1
PRG4 proteoglycan 4
PRRC1 proline-rich coiled-coil 1
PTK6 protein tyrosine kinase 6
RAB3B RAB3B, member RAS oncogene family
RAI2 retinoic acid induced 2
RBPMS2 RNA binding protein with multiple splicing 2
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RFESD Rieske (Fe-S) domain containing
RFK riboflavin kinase
RHBDD1 rhomboid domain containing 1
RHOA ras homolog family member A
RNF130 ring finger protein 130
RNF185 ring finger protein 185
ROPN1 rhophilin associated tail protein 1
ROPN1B rhophilin associated tail protein 1B
RRBP1 ribosome binding protein 1
RTN4R reticulon 4 receptor
S100P S100 calcium binding protein P
SAR1B secretion associated, Ras related GTPase 1B
SATB2 SATB homeobox 2
SCAMP1 secretory carrier membrane protein 1
SCARB2 scavenger receptor class B, member 2
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SDC1 syndecan 1
SEC24A SEC24 family member A
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SERINC1 serine incorporator 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SHC4 SHC (Src homology 2 domain containing) family, member 4
SHISA6 shisa family member 6
SIAE sialic acid acetylesterase
SIGMAR1 sigma non-opioid intracellular receptor 1
SIRPA signal-regulatory protein alpha
SIRPB1 signal-regulatory protein beta 1
SKAP2 src kinase associated phosphoprotein 2
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC38A3 solute carrier family 38, member 3
SLC39A11 solute carrier family 39, member 11
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC51B solute carrier family 51, beta subunit
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLPI secretory leukocyte peptidase inhibitor
SND1 staphylococcal nuclease and tudor domain containing 1
SNORA52 small nucleolar RNA, H/ACA box 52
SNX18 sorting nexin 18
SORT1 sortilin 1
SREBF2 sterol regulatory element binding transcription factor 2
SRPR signal recognition particle receptor (docking protein)
SSMEM1 serine-rich single-pass membrane protein 1
SUMF2 sulfatase modifying factor 2
SURF4 surfeit 4
SYNPO synaptopodin
SYPL1 synaptophysin-like 1
SYTL4 synaptotagmin-like 4
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TBL1X transducin (beta)-like 1X-linked
TCEB3C transcription elongation factor B polypeptide 3C (elongin A3)
TFR2 transferrin receptor 2
THRB thyroid hormone receptor, beta
THSD7A thrombospondin, type I, domain containing 7A
TJP3 tight junction protein 3
TLE6 transducin-like enhancer of split 6
TM6SF2 transmembrane 6 superfamily member 2
TMCO3 transmembrane and coiled-coil domains 3
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMEM106B transmembrane protein 106B
TMEM135 transmembrane protein 135
TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough
TMEM214 transmembrane protein 214
TMEM232 transmembrane protein 232
TMEM248 transmembrane protein 248
TMEM45B transmembrane protein 45B
TMEM82 transmembrane protein 82
TMPRSS6 transmembrane protease, serine 6
TNIP3 TNFAIP3 interacting protein 3
TOB2 transducer of ERBB2, 2
TOM1 target of myb1 (chicken)
TPI1P2 triosephosphate isomerase 1 pseudogene 2
TPK1 thiamin pyrophosphokinase 1
TSG1 tumor suppressor TSG1
TXNDC11 thioredoxin domain containing 11
TXNDC15 thioredoxin domain containing 15
TYMP thymidine phosphorylase
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
UBA1 ubiquitin-like modifier activating enzyme 1
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4
VSIG2 V-set and immunoglobulin domain containing 2
VWA3B von Willebrand factor A domain containing 3B
VWA8 von Willebrand factor A domain containing 8
VWF von Willebrand factor
WDR7 WD repeat domain 7
WNT5B wingless-type MMTV integration site family, member 5B
XDH xanthine dehydrogenase
XK X-linked Kx blood group
XKR8 XK, Kell blood group complex subunit-related family, member 8
YIPF3 Yip1 domain family, member 3
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZC2HC1B zinc finger, C2HC-type containing 1B
ZDHHC8 zinc finger, DHHC-type containing 8
ZFHX3 zinc finger homeobox 3
ZFPM1 zinc finger protein, FOG family member 1
ZFYVE28 zinc finger, FYVE domain containing 28
ZNF720 zinc finger protein 720

low expression

Symbol Name
ANAPC5 anaphase promoting complex subunit 5
BRAP BRCA1 associated protein
C12ORF43 chromosome 12 open reading frame 43
C12ORF65 chromosome 12 open reading frame 65
DIABLO diablo, IAP-binding mitochondrial protein
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MIS12 MIS12 kinetochore complex component
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
SPPL3 signal peptide peptidase like 3
TRIAP1 TP53 regulated inhibitor of apoptosis 1