Liver Cirrhosis, Alcoholic Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

61 genes associated with the Liver Cirrhosis, Alcoholic phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ACE angiotensin I converting enzyme
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APOE apolipoprotein E
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DRD2 dopamine receptor D2
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HFE hemochromatosis
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
IL10 interleukin 10
IL12B interleukin 12B
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL4 interleukin 4
IL6 interleukin 6
KDR kinase insert domain receptor
KRT8 keratin 8, type II
MMP3 matrix metallopeptidase 3
MPO myeloperoxidase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
PNPLA3 patatin-like phospholipase domain containing 3
PPARG peroxisome proliferator-activated receptor gamma
RGS4 regulator of G-protein signaling 4
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SOD2 superoxide dismutase 2, mitochondrial
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1