Leukemia, Myeloid, Acute Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

369 genes associated with the Leukemia, Myeloid, Acute phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABHD16A abhydrolase domain containing 16A
ACAA1 acetyl-CoA acyltransferase 1
ACAD11 acyl-CoA dehydrogenase family, member 11
ACE angiotensin I converting enzyme
ADAM19 ADAM metallopeptidase domain 19
ADAP1 ArfGAP with dual PH domains 1
AKR1C3 aldo-keto reductase family 1, member C3
ALOX12 arachidonate 12-lipoxygenase
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALOX15 arachidonate 15-lipoxygenase
ALOX15B arachidonate 15-lipoxygenase, type B
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ALOXE3 arachidonate lipoxygenase 3
APOA2 apolipoprotein A-II
ARID5B AT rich interactive domain 5B (MRF1-like)
ASXL1 additional sex combs like transcriptional regulator 1
ATG9B autophagy related 9B
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
BPI bactericidal/permeability-increasing protein
BRD7 bromodomain containing 7
C1D C1D nuclear receptor corepressor
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QBP complement component 1, q subcomponent binding protein
C1QC complement component 1, q subcomponent, C chain
C1RL complement component 1, r subcomponent-like
C1S complement component 1, s subcomponent
C2 complement component 2
C3 complement component 3
C4BPA complement component 4 binding protein, alpha
C4BPB complement component 4 binding protein, beta
C5 complement component 5
C5AR1 complement component 5a receptor 1
C6 complement component 6
C7 complement component 7
C8A complement component 8, alpha polypeptide
C8B complement component 8, beta polypeptide
C8G complement component 8, gamma polypeptide
C9 complement component 9
CASP9 caspase 9, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL1 chemokine (C-C motif) ligand 1
CCL11 chemokine (C-C motif) ligand 11
CCL13 chemokine (C-C motif) ligand 13
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL24 chemokine (C-C motif) ligand 24
CCL26 chemokine (C-C motif) ligand 26
CCL5 chemokine (C-C motif) ligand 5
CCL7 chemokine (C-C motif) ligand 7
CCL8 chemokine (C-C motif) ligand 8
CCNH cyclin H
CCR1 chemokine (C-C motif) receptor 1
CCR3 chemokine (C-C motif) receptor 3
CCR4 chemokine (C-C motif) receptor 4
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CCR8 chemokine (C-C motif) receptor 8
CCR9 chemokine (C-C motif) receptor 9
CD14 CD14 molecule
CD180 CD180 molecule
CD209 CD209 molecule
CD33 CD33 molecule
CD46 CD46 molecule, complement regulatory protein
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD93 CD93 molecule
CDA cytidine deaminase
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2B-AS1 CDKN2B antisense RNA 1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CFB complement factor B
CHIT1 chitinase 1 (chitotriosidase)
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
CLCA1 chloride channel accessory 1
CLCA2 chloride channel accessory 2
CNTNAP1 contactin associated protein 1
CORO1C coronin, actin binding protein, 1C
CRP C-reactive protein, pentraxin-related
CSF3R colony stimulating factor 3 receptor (granulocyte)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXXC5 CXXC finger protein 5
CYBA cytochrome b-245, alpha polypeptide
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DCK deoxycytidine kinase
DDR1 discoidin domain receptor tyrosine kinase 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DEFA3 defensin, alpha 3, neutrophil-specific
DEFA4 defensin, alpha 4, corticostatin
DEFA5 defensin, alpha 5, Paneth cell-specific
DEFA6 defensin, alpha 6, Paneth cell-specific
DEFB1 defensin, beta 1
DEFB118 defensin, beta 118
DEFB119 defensin, beta 119
DEFB126 defensin, beta 126
DEFB127 defensin, beta 127
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DLG5 discs, large homolog 5 (Drosophila)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOK2 docking protein 2, 56kDa
EED embryonic ectoderm development
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPO erythropoietin
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC5 excision repair cross-complementation group 5
ETV6 ets variant 6
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F5 coagulation factor V (proaccelerin, labile factor)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FES FES proto-oncogene, tyrosine kinase
FGF2 fibroblast growth factor 2 (basic)
FLJ90680 FLJ90680 protein
FLT3 fms-related tyrosine kinase 3
FOXJ2 forkhead box J2
GATA1 GATA binding protein 1 (globin transcription factor 1)
GFI1 growth factor independent 1 transcription repressor
GGCT gamma-glutamylcyclotransferase
GLS glutaminase
GPR108 G protein-coupled receptor 108
GSTM1 glutathione S-transferase mu 1
GSTM5 glutathione S-transferase mu 5
GSTO2 glutathione S-transferase omega 2
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HES7 hes family bHLH transcription factor 7
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICAM1 intercellular adhesion molecule 1
ICAM2 intercellular adhesion molecule 2
ICAM3 intercellular adhesion molecule 3
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
ICAM5 intercellular adhesion molecule 5, telencephalin
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL11RA interleukin 11 receptor, alpha
IL17A interleukin 17A
IL17C interleukin 17C
IL17F interleukin 17F
IL23R interleukin 23 receptor
IL6 interleukin 6
INSL3 insulin-like 3 (Leydig cell)
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
IRF1 interferon regulatory factor 1
IRF3 interferon regulatory factor 3
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR2DL5B killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5B
KIR2DP1 killer cell immunoglobulin-like receptor, two domains, pseudogene 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KIR3DP1 killer cell immunoglobulin-like receptor, three domains, pseudogene 1
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK1 kallikrein 1
KLK15 kallikrein-related peptidase 15
KLK2 kallikrein-related peptidase 2
KLK4 kallikrein-related peptidase 4
KLK6 kallikrein-related peptidase 6
KLK7 kallikrein-related peptidase 7
KLKB1 kallikrein B, plasma (Fletcher factor) 1
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
LBP lipopolysaccharide binding protein
LMAN1 lectin, mannose-binding, 1
LPO lactoperoxidase
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LY6G6D lymphocyte antigen 6 complex, locus G6D
LY96 lymphocyte antigen 96
MAL mal, T-cell differentiation protein
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MBP myelin basic protein
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEFV Mediterranean fever
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MPO myeloperoxidase
MTAP methylthioadenosine phosphorylase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MUC6 mucin 6, oligomeric mucus/gel-forming
MUC7 mucin 7, secreted
MYD88 myeloid differentiation primary response 88
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NBN nibrin
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NIPAL4 NIPA-like domain containing 4
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NQO1 NAD(P)H dehydrogenase, quinone 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NT5C2 5'-nucleotidase, cytosolic II
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OR10J3 olfactory receptor, family 10, subfamily J, member 3
PDCD10 programmed cell death 10
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHF6 PHD finger protein 6
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLK2 polo-like kinase 2
PML promyelocytic leukemia
PTGDR prostaglandin D2 receptor (DP)
PTGDR2 prostaglandin D2 receptor 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAD51 RAD51 recombinase
RARA retinoic acid receptor, alpha
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RAVER1 ribonucleoprotein, PTB-binding 1
RBBP4 retinoblastoma binding protein 4
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RGS6 regulator of G-protein signaling 6
RPS4XP13 ribosomal protein S4X pseudogene 13
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
RUNX1 runt-related transcription factor 1
SCAF4 SR-related CTD-associated factor 4
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SECTM1 secreted and transmembrane 1
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SF3B1 splicing factor 3b, subunit 1, 155kDa
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SMC1A structural maintenance of chromosomes 1A
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOCS4 suppressor of cytokine signaling 4
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
SOS1 son of sevenless homolog 1 (Drosophila)
SPI1 Spi-1 proto-oncogene
STAG1 stromal antigen 1
STAG2 stromal antigen 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK19 serine/threonine kinase 19
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUZ12 SUZ12 polycomb repressive complex 2 subunit
TAL1 T-cell acute lymphocytic leukemia 1
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TET1 tet methylcytosine dioxygenase 1
TET2 tet methylcytosine dioxygenase 2
TET3 tet methylcytosine dioxygenase 3
TICAM1 toll-like receptor adaptor molecule 1
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLR9 toll-like receptor 9
TMCO6 transmembrane and coiled-coil domains 6
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOLLIP toll interacting protein
TP53 tumor protein p53
TPMT thiopurine S-methyltransferase
TRAM1 translocation associated membrane protein 1
TSLP thymic stromal lymphopoietin
TWF1 twinfilin actin binding protein 1
TWF2 twinfilin actin binding protein 2
TYK2 tyrosine kinase 2
TYMS thymidylate synthetase
U2AF1 U2 small nuclear RNA auxiliary factor 1
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
WDHD1 WD repeat and HMG-box DNA binding protein 1
WT1 Wilms tumor 1
XDH xanthine dehydrogenase
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF76 zinc finger protein 76
ZP1 zona pellucida glycoprotein 1 (sperm receptor)