Leukemia, Lymphoid Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D007945
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Genes

300 genes/proteins associated with the disease Leukemia, Lymphoid from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
POT1 protection of telomeres 1 2.88009
CLPTM1L CLPTM1-like 2.88009
MECOM MDS1 and EVI1 complex locus 2.88009
TERT telomerase reverse transcriptase 2.88009
KMT2A lysine (K)-specific methyltransferase 2A 2.88009
AICDA activation-induced cytidine deaminase 2.88009
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 2.88009
IPCEF1 interaction protein for cytohesin exchange factors 1 2.88009
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.93444
BCL2L1 BCL2-like 1 1.89845
PARP1 poly (ADP-ribose) polymerase 1 1.88589
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.85712
BCL2 B-cell CLL/lymphoma 2 1.81447
FAS Fas cell surface death receptor 1.81111
H2AFX H2A histone family, member X 1.77724
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.75954
TYMS thymidylate synthetase 1.70927
BIRC3 baculoviral IAP repeat containing 3 1.6993
BAX BCL2-associated X protein 1.69888
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.69825
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.68996
PRC1 protein regulator of cytokinesis 1 1.68443
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.6621
RRM2 ribonucleotide reductase M2 1.66124
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.65045
GSTM1 glutathione S-transferase mu 1 1.63698
TP53 tumor protein p53 1.62579
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.62106
CDK2 cyclin-dependent kinase 2 1.61529
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.61084
TNF tumor necrosis factor 1.60547
MAPK8 mitogen-activated protein kinase 8 1.56923
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.56681
MCL1 myeloid cell leukemia 1 1.54961
IL1B interleukin 1, beta 1.54523
CCNB1 cyclin B1 1.54499
VCAM1 vascular cell adhesion molecule 1 1.54184
RB1 retinoblastoma 1 1.53772
BRCA1 breast cancer 1, early onset 1.53036
CAT catalase 1.52914
IFNG interferon, gamma 1.51759
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.51657
MAPK9 mitogen-activated protein kinase 9 1.51607
ERBB2 erb-b2 receptor tyrosine kinase 2 1.51481
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.51305
BTG2 BTG family, member 2 1.51055
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.50675
MAPK14 mitogen-activated protein kinase 14 1.49787
CCL2 chemokine (C-C motif) ligand 2 1.49019
NAMPT nicotinamide phosphoribosyltransferase 1.47838
IL4 interleukin 4 1.47686
TIMP1 TIMP metallopeptidase inhibitor 1 1.45962
BUB3 BUB3 mitotic checkpoint protein 1.45803
JUN jun proto-oncogene 1.45273
GADD45A growth arrest and DNA-damage-inducible, alpha 1.44653
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.43293
COL1A1 collagen, type I, alpha 1 1.43021
BBC3 BCL2 binding component 3 1.42616
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.41829
BIRC2 baculoviral IAP repeat containing 2 1.41613
GLS glutaminase 1.41559
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 1.41285
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.41008
CCNE1 cyclin E1 1.40036
CCNA2 cyclin A2 1.39198
F3 coagulation factor III (thromboplastin, tissue factor) 1.38752
E2F1 E2F transcription factor 1 1.38441
CXCL8 chemokine (C-X-C motif) ligand 8 1.38327
MGMT O-6-methylguanine-DNA methyltransferase 1.38015
ATF3 activating transcription factor 3 1.37761
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.37619
PKP2 plakophilin 2 1.3759
TGFB1 transforming growth factor, beta 1 1.3736
BRCA2 breast cancer 2, early onset 1.3682
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.35934
CDK1 cyclin-dependent kinase 1 1.35821
VEGFA vascular endothelial growth factor A 1.34547
IGFBP3 insulin-like growth factor binding protein 3 1.34111
CCND1 cyclin D1 1.34024
UBE2C ubiquitin-conjugating enzyme E2C 1.33612
SOD2 superoxide dismutase 2, mitochondrial 1.33583
MAPK3 mitogen-activated protein kinase 3 1.33346
BIRC5 baculoviral IAP repeat containing 5 1.33287
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.33287
AURKB aurora kinase B 1.32607
MAPK1 mitogen-activated protein kinase 1 1.32458
IL6 interleukin 6 1.32132
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.31956
CTSL cathepsin L 1.31837
BMP4 bone morphogenetic protein 4 1.31626
BAD BCL2-associated agonist of cell death 1.31119
IL10 interleukin 10 1.31089
LMCD1 LIM and cysteine-rich domains 1 1.30881
IGFBP5 insulin-like growth factor binding protein 5 1.30881
CLU clusterin 1.3039
FASLG Fas ligand (TNF superfamily, member 6) 1.30177
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.29966
S100P S100 calcium binding protein P 1.29595
CYCS cytochrome c, somatic 1.29595
DUSP10 dual specificity phosphatase 10 1.29256
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.29225
PCNA proliferating cell nuclear antigen 1.29011
RAD51 RAD51 recombinase 1.28889
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.28703
FOS FBJ murine osteosarcoma viral oncogene homolog 1.28641
THBS1 thrombospondin 1 1.28364
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.28333
CCNG1 cyclin G1 1.27533
CXCL10 chemokine (C-X-C motif) ligand 10 1.27347
CFLAR CASP8 and FADD-like apoptosis regulator 1.27039
IRS1 insulin receptor substrate 1 1.26856
BID BH3 interacting domain death agonist 1.26607
CCND3 cyclin D3 1.26545
MPO myeloperoxidase 1.26421
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.2599
IL1RN interleukin 1 receptor antagonist 1.25929
GPX3 glutathione peroxidase 3 1.25929
DDIT3 DNA-damage-inducible transcript 3 1.25619
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.25463
KDM4B lysine (K)-specific demethylase 4B 1.25121
SESN1 sestrin 1 1.25028
SGK1 serum/glucocorticoid regulated kinase 1 1.24843
NOS3 nitric oxide synthase 3 (endothelial cell) 1.24307
LMNB1 lamin B1 1.24056
CD14 CD14 molecule 1.23074
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.23042
GPX1 glutathione peroxidase 1 1.22979
CD44 CD44 molecule (Indian blood group) 1.22948
COL1A2 collagen, type I, alpha 2 1.21951
PTPRE protein tyrosine phosphatase, receptor type, E 1.21727
MCM4 minichromosome maintenance complex component 4 1.21631
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.21501
DCN decorin 1.21206
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.21076
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.20881
SPP1 secreted phosphoprotein 1 1.20848
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.20295
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.20097
UNG uracil-DNA glycosylase 1.20064
CDC25B cell division cycle 25B 1.19868
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.19835
DIABLO diablo, IAP-binding mitochondrial protein 1.19672
PDE4B phosphodiesterase 4B, cAMP-specific 1.19213
NFE2L1 nuclear factor, erythroid 2-like 1 1.19113
BTG1 B-cell translocation gene 1, anti-proliferative 1.19014
BECN1 beclin 1, autophagy related 1.19014
GSTP1 glutathione S-transferase pi 1 1.18882
STK17B serine/threonine kinase 17b 1.18718
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.18293
NRP1 neuropilin 1 1.17993
NASP nuclear autoantigenic sperm protein (histone-binding) 1.17959
DHRS2 dehydrogenase/reductase (SDR family) member 2 1.17926
E2F3 E2F transcription factor 3 1.17926
CDKN2A cyclin-dependent kinase inhibitor 2A 1.17827
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.17629
AURKA aurora kinase A 1.17596
HTRA2 HtrA serine peptidase 2 1.17563
EEF2 eukaryotic translation elongation factor 2 1.17399
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.17235
RGS1 regulator of G-protein signaling 1 1.17202
PLAT plasminogen activator, tissue 1.17134
GDF15 growth differentiation factor 15 1.17101
TOP2A topoisomerase (DNA) II alpha 170kDa 1.17101
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.16866
CCNE2 cyclin E2 1.16666
TAGLN transgelin 1.16666
FLT1 fms-related tyrosine kinase 1 1.16633
STAT1 signal transducer and activator of transcription 1, 91kDa 1.16533
VIM vimentin 1.16302
NKAIN1 Na+/K+ transporting ATPase interacting 1 1.16269
MIR29A microRNA 29a 1.16269
RAD51C RAD51 paralog C 1.16137
TP53I3 tumor protein p53 inducible protein 3 1.16104
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.15627
PRDX2 peroxiredoxin 2 1.15526
EIF4A1 eukaryotic translation initiation factor 4A1 1.15425
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.15425
GFRA1 GDNF family receptor alpha 1 1.15425
EGR1 early growth response 1 1.15256
S100A9 S100 calcium binding protein A9 1.15156
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.15156
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 1.15089
CREBBP CREB binding protein 1.14989
ODC1 ornithine decarboxylase 1 1.1485
IL2 interleukin 2 1.14507
MELK maternal embryonic leucine zipper kinase 1.1437
CALR calreticulin 1.14098
BTG3 BTG family, member 3 1.14098
CDK4 cyclin-dependent kinase 4 1.14064
CDC25C cell division cycle 25C 1.13586
TRAF1 TNF receptor-associated factor 1 1.13109
RARA retinoic acid receptor, alpha 1.1294
ANXA2 annexin A2 1.12906
BAG1 BCL2-associated athanogene 1.12838
C1QA complement component 1, q subcomponent, A chain 1.12219
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.12219
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.11809
IER3 immediate early response 3 1.11639
DONSON downstream neighbor of SON 1.11606
RNF144A ring finger protein 144A 1.11571
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.11466
RFC3 replication factor C (activator 1) 3, 38kDa 1.11325
MAP2K3 mitogen-activated protein kinase kinase 3 1.11325
SRXN1 sulfiredoxin 1 1.11325
TXNIP thioredoxin interacting protein 1.1129
CCNB2 cyclin B2 1.11151
CDCA8 cell division cycle associated 8 1.10803
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.10769
ACHE acetylcholinesterase (Yt blood group) 1.10631
EDNRB endothelin receptor type B 1.10527
CHEK2 checkpoint kinase 2 1.10527
TGFB2 transforming growth factor, beta 2 1.10388
RBM17 RNA binding motif protein 17 1.10317
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 1.10317
BAK1 BCL2-antagonist/killer 1 1.10246
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 1.10211
SDC2 syndecan 2 1.09646
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 1.09646
CXCR4 chemokine (C-X-C motif) receptor 4 1.0919
CCND2 cyclin D2 1.09047
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 1.08868
LBP lipopolysaccharide binding protein 1.08619
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 1.08584
NREP neuronal regeneration related protein 1.08584
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 1.08584
CHEK1 checkpoint kinase 1 1.08478
SP1 Sp1 transcription factor 1.08478
ESR1 estrogen receptor 1 1.08442
DOK4 docking protein 4 1.08442
KIF23 kinesin family member 23 1.08337
TYMP thymidine phosphorylase 1.08337
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 1.08091
BMP7 bone morphogenetic protein 7 1.08091
ATM ATM serine/threonine kinase 1.08055
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.08019
CAV1 caveolin 1, caveolae protein, 22kDa 1.07911
HMMR hyaluronan-mediated motility receptor (RHAMM) 1.07553
SP4 Sp4 transcription factor 1.07305
ASS1 argininosuccinate synthase 1 1.06844
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.06844
RAD50 RAD50 homolog (S. cerevisiae) 1.06625
FYN FYN proto-oncogene, Src family tyrosine kinase 1.06406
PTGER4 prostaglandin E receptor 4 (subtype EP4) 1.0637
CP ceruloplasmin (ferroxidase) 1.06261
RGL1 ral guanine nucleotide dissociation stimulator-like 1 1.06225
MT1X metallothionein 1X 1.06116
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.06116
CD68 CD68 molecule 1.059
IGFBP4 insulin-like growth factor binding protein 4 1.059
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.05685
CDC25A cell division cycle 25A 1.05685
EP300 E1A binding protein p300 1.05685
HSPA2 heat shock 70kDa protein 2 1.05685
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 1.05648
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.05648
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.05648
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.05461
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.05423
BCL2A1 BCL2-related protein A1 1.05423
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.05349
ICAM1 intercellular adhesion molecule 1 1.05274
PARP2 poly (ADP-ribose) polymerase 2 1.05163
SESN2 sestrin 2 1.04978
CLDN1 claudin 1 1.04978
NUSAP1 nucleolar and spindle associated protein 1 1.04721
SRI sorcin 1.04721
MT2A metallothionein 2A 1.04721
MMP16 matrix metallopeptidase 16 (membrane-inserted) 1.04684
PMP22 peripheral myelin protein 22 1.04538
SIRT1 sirtuin 1 1.04465
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.04314
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.04276
MAP2K6 mitogen-activated protein kinase kinase 6 1.04276
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 1.04126
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.04088
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.04051
UROD uroporphyrinogen decarboxylase 1.03752
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 1.03715
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.03641
MIR34A microRNA 34a 1.03345
KIF20A kinesin family member 20A 1.03235
PLK1 polo-like kinase 1 1.03009
CDKN3 cyclin-dependent kinase inhibitor 3 1.03009
CCNG2 cyclin G2 1.03009
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.02858
GHR growth hormone receptor 1.02783
ALB albumin 1.02447
SMAD2 SMAD family member 2 1.02188
GSN gelsolin 1.02003
CSTA cystatin A (stefin A) 1.01928
PTEN phosphatase and tensin homolog 1.0189
G0S2 G0/G1 switch 2 1.01814
TSC22D3 TSC22 domain family, member 3 1.01776
HBB hemoglobin, beta 1.01776
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.01739
PPARG peroxisome proliferator-activated receptor gamma 1.01587
CDC6 cell division cycle 6 1.01587
NOX4 NADPH oxidase 4 1.01174
BST2 bone marrow stromal cell antigen 2 1.01137
LGALS1 lectin, galactoside-binding, soluble, 1 1.01025