Leukemia, Chronic T-Cell_T lymphocyte_GSE5788 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE5788
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Genes

600 genes differentially expressed during Leukemia, Chronic T-Cell_T lymphocyte_GSE5788 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
DDRGK1 DDRGK domain containing 1 3.48068
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 3.33602
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 3.22735
CSPP1 centrosome and spindle pole associated protein 1 3.14773
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 3.03559
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 2.96187
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 2.88543
SCAP SREBF chaperone 2.80106
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 2.77246
GCLC glutamate-cysteine ligase, catalytic subunit 2.71557
RRP1B ribosomal RNA processing 1B 2.62796
TAOK2 TAO kinase 2 2.61843
PGAP2 post-GPI attachment to proteins 2 2.60295
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 2.57571
DEDD death effector domain containing 2.56698
PDCD6IP programmed cell death 6 interacting protein 2.55957
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 2.54929
PUF60 poly-U binding splicing factor 60KDa 2.53858
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 2.50917
CHD4 chromodomain helicase DNA binding protein 4 2.50398
HMBS hydroxymethylbilane synthase 2.48651
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 2.48355
ZNF263 zinc finger protein 263 2.47516
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 2.47039
WIPI2 WD repeat domain, phosphoinositide interacting 2 2.44507
DESI1 desumoylating isopeptidase 1 2.43731
FAM50B family with sequence similarity 50, member B 2.39071
MEST mesoderm specific transcript 2.37557
RBM42 RNA binding motif protein 42 2.37368
ADNP activity-dependent neuroprotector homeobox 2.36477
GAL3ST4 galactose-3-O-sulfotransferase 4 2.34369
LARP1 La ribonucleoprotein domain family, member 1 2.30161
PMS2P3 postmeiotic segregation increased 2 pseudogene 3 2.29247
KAT2A K(lysine) acetyltransferase 2A 2.27866
ZNF7 zinc finger protein 7 2.26544
ZZZ3 zinc finger, ZZ-type containing 3 2.23725
PMS2P1 postmeiotic segregation increased 2 pseudogene 1 2.23407
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 2.21224
SCN11A sodium channel, voltage gated, type XI alpha subunit 2.20984
UBAP2L ubiquitin associated protein 2-like 2.19749
CCNG2 cyclin G2 2.17133
UBAP2 ubiquitin associated protein 2 2.16797
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 2.15456
CLCN1 chloride channel, voltage-sensitive 1 2.144
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 2.14157
STK19 serine/threonine kinase 19 2.13973
SEPT9 septin 9 2.12718
GPAA1 glycosylphosphatidylinositol anchor attachment 1 2.11287
RBMS1 RNA binding motif, single stranded interacting protein 1 2.10862
DOLPP1 dolichyldiphosphatase 1 2.10456
CAPN5 calpain 5 2.09201
RCOR1 REST corepressor 1 2.09037
VDAC3 voltage-dependent anion channel 3 2.09021
FKBP1A FK506 binding protein 1A, 12kDa 2.0826
AMPD2 adenosine monophosphate deaminase 2 2.04212
IPO4 importin 4 2.04102
RABEP2 rabaptin, RAB GTPase binding effector protein 2 2.03993
C18ORF25 chromosome 18 open reading frame 25 2.03604
C12ORF10 chromosome 12 open reading frame 10 2.03358
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 2.02843
WWC1 WW and C2 domain containing 1 2.0125
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 2.0092
TLE2 transducin-like enhancer of split 2 1.99765
BRMS1 breast cancer metastasis suppressor 1 1.99731
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 1.99715
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 1.99441
AAMP angio-associated, migratory cell protein 1.97671
MBOAT1 membrane bound O-acyltransferase domain containing 1 1.97275
CPSF3L cleavage and polyadenylation specific factor 3-like 1.9614
NEO1 neogenin 1 1.96042
SRPK1 SRSF protein kinase 1 1.95794
CCHCR1 coiled-coil alpha-helical rod protein 1 1.95549
ANAPC1 anaphase promoting complex subunit 1 1.95496
MTDH metadherin 1.94956
MDM1 Mdm1 nuclear protein homolog (mouse) 1.94198
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 1.93422
FZD6 frizzled class receptor 6 1.93191
TMED3 transmembrane emp24 protein transport domain containing 3 1.92862
TMEM147 transmembrane protein 147 1.92306
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 1.92074
GGT1 gamma-glutamyltransferase 1 1.91742
MCM2 minichromosome maintenance complex component 2 1.91531
ROGDI rogdi homolog (Drosophila) 1.91093
POLB polymerase (DNA directed), beta 1.91025
HAUS4 HAUS augmin-like complex, subunit 4 1.9102
TARBP2 TAR (HIV-1) RNA binding protein 2 1.90822
FBXO46 F-box protein 46 1.90627
XKR8 XK, Kell blood group complex subunit-related family, member 8 1.90325
MPP1 membrane protein, palmitoylated 1, 55kDa 1.90296
CAMTA2 calmodulin binding transcription activator 2 1.90209
AGPS alkylglycerone phosphate synthase 1.89433
PRMT3 protein arginine methyltransferase 3 1.88884
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 1.88836
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 1.88477
POLD2 polymerase (DNA directed), delta 2, accessory subunit 1.88247
PTDSS1 phosphatidylserine synthase 1 1.8793
NUTF2 nuclear transport factor 2 1.87486
RBM28 RNA binding motif protein 28 1.86452
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 1.86356
APOO apolipoprotein O 1.86328
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 1.8632
MYDGF myeloid-derived growth factor 1.86055
DUT deoxyuridine triphosphatase 1.85671
ZMYM4 zinc finger, MYM-type 4 1.84708
C1QTNF3 C1q and tumor necrosis factor related protein 3 1.84701
PDIA5 protein disulfide isomerase family A, member 5 1.84685
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 1.84518
DNPEP aspartyl aminopeptidase 1.83554
CCND3 cyclin D3 1.83245
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A 1.83103
MYL5 myosin, light chain 5, regulatory 1.82658
UBE3B ubiquitin protein ligase E3B 1.82541
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 1.82315
CNTFR ciliary neurotrophic factor receptor 1.82284
ZNF593 zinc finger protein 593 1.82033
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 1.81559
TRAPPC3 trafficking protein particle complex 3 1.81518
ATXN10 ataxin 10 1.81447
ATAD3A ATPase family, AAA domain containing 3A 1.80885
COMMD10 COMM domain containing 10 1.804
SPEN spen family transcriptional repressor 1.79857
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 1.79806
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.79726
FAM149A family with sequence similarity 149, member A 1.77875
UIMC1 ubiquitin interaction motif containing 1 1.77084
STOML2 stomatin (EPB72)-like 2 1.77051
DGAT1 diacylglycerol O-acyltransferase 1 1.76955
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 1.76894
IPO13 importin 13 1.76487
QARS glutaminyl-tRNA synthetase 1.75926
ANAPC15 anaphase promoting complex subunit 15 1.75879
ZNF592 zinc finger protein 592 1.75759
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 1.75494
TCEA1 transcription elongation factor A (SII), 1 1.75268
MKL2 MKL/myocardin-like 2 1.752
TRAPPC9 trafficking protein particle complex 9 1.74844
BRD4 bromodomain containing 4 1.74709
PGK1 phosphoglycerate kinase 1 1.74689
TMCC2 transmembrane and coiled-coil domain family 2 1.74475
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.74421
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 1.74264
PRKCZ protein kinase C, zeta 1.74074
RPL35 ribosomal protein L35 1.73952
NFS1 NFS1 cysteine desulfurase 1.73382
CRELD2 cysteine-rich with EGF-like domains 2 1.73261
RFX5 regulatory factor X, 5 (influences HLA class II expression) 1.72658
ARF4 ADP-ribosylation factor 4 1.72093
KIAA0753 KIAA0753 1.70937
C17ORF85 chromosome 17 open reading frame 85 1.7075
OR7E38P olfactory receptor, family 7, subfamily E, member 38 pseudogene 1.70295
OVGP1 oviductal glycoprotein 1, 120kDa 1.70179
E2F1 E2F transcription factor 1 1.70084
E2F4 E2F transcription factor 4, p107/p130-binding 1.70032
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 1.69753
BCR breakpoint cluster region 1.69694
BLMH bleomycin hydrolase 1.69588
MRPS12 mitochondrial ribosomal protein S12 1.69543
TNRC6B trinucleotide repeat containing 6B 1.69542
PRPF31 pre-mRNA processing factor 31 1.69283
VPS13B vacuolar protein sorting 13 homolog B (yeast) 1.69135
NBN nibrin 1.68896
TEX10 testis expressed 10 1.68474
CHPF chondroitin polymerizing factor 1.67706
TBC1D13 TBC1 domain family, member 13 1.6748
GPS2 G protein pathway suppressor 2 1.67305
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 1.67255
VWA8 von Willebrand factor A domain containing 8 1.66934
MYBBP1A MYB binding protein (P160) 1a 1.6573
GCAT glycine C-acetyltransferase 1.65687
WDR70 WD repeat domain 70 1.65535
FLOT1 flotillin 1 1.65389
TMEM5 transmembrane protein 5 1.65251
ZNF783 zinc finger family member 783 1.65185
CDK13 cyclin-dependent kinase 13 1.6481
CHGB chromogranin B 1.64577
CPNE3 copine III 1.64532
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 1.63927
FAM63A family with sequence similarity 63, member A 1.63753
TATDN2 TatD DNase domain containing 2 1.63609
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 1.63576
MTA1 metastasis associated 1 1.63394
PQLC1 PQ loop repeat containing 1 1.62801
LYST lysosomal trafficking regulator 1.62385
RABAC1 Rab acceptor 1 (prenylated) 1.6235
RPSAP20 ribosomal protein SA pseudogene 20 1.61974
AHCY adenosylhomocysteinase 1.61653
SIK3 SIK family kinase 3 1.6148
ZFAND3 zinc finger, AN1-type domain 3 1.6139
ZMYM3 zinc finger, MYM-type 3 1.60788
U2AF2 U2 small nuclear RNA auxiliary factor 2 1.60657
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) 1.60413
WDR61 WD repeat domain 61 1.60187
TJAP1 tight junction associated protein 1 (peripheral) 1.59797
MRPS35 mitochondrial ribosomal protein S35 1.59661
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 1.59295
METTL1 methyltransferase like 1 1.59261
KLHDC4 kelch domain containing 4 1.59256
PRR14 proline rich 14 1.59248
ETHE1 ethylmalonic encephalopathy 1 1.58991
TUBGCP4 tubulin, gamma complex associated protein 4 1.5866
PDCD11 programmed cell death 11 1.58616
COL6A2 collagen, type VI, alpha 2 1.58262
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 1.58245
RHOT2 ras homolog family member T2 1.58114
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 1.58012
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 1.57618
DEAF1 DEAF1 transcription factor 1.57579
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 1.57388
MBTPS1 membrane-bound transcription factor peptidase, site 1 1.57388
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 1.57224
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 1.57152
TOP2B topoisomerase (DNA) II beta 180kDa 1.56978
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 1.56631
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 1.5648
METTL9 methyltransferase like 9 1.56469
UBN1 ubinuclein 1 1.56352
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 1.56339
UROS uroporphyrinogen III synthase 1.55926
ZNF629 zinc finger protein 629 1.55779
ARMCX3 armadillo repeat containing, X-linked 3 1.55485
C19ORF54 chromosome 19 open reading frame 54 1.55267
UBE2H ubiquitin-conjugating enzyme E2H 1.54909
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 1.54537
NOL10 nucleolar protein 10 1.54429
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 1.54429
RAB1B RAB1B, member RAS oncogene family 1.5435
PTPRU protein tyrosine phosphatase, receptor type, U 1.54302
THADA thyroid adenoma associated 1.5403
NDRG2 NDRG family member 2 1.53537
LYPLA1 lysophospholipase I 1.53524
XYLT1 xylosyltransferase I 1.53509
SYNGR2 synaptogyrin 2 1.53212
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 1.53073
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 1.52917
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 1.52815
PGLS 6-phosphogluconolactonase 1.52555
PRY PTPN13-like, Y-linked 1.52223
ACF Asymmetric crying facies (Cayler cardiofacial syndrome) 1.52102
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 1.51758
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 1.51414
MFN2 mitofusin 2 1.50993
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1.50667
MRPS2 mitochondrial ribosomal protein S2 1.50607
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.50454
CYC1 cytochrome c-1 1.50217
FAM102A family with sequence similarity 102, member A 1.49971
RING1 ring finger protein 1 1.49868
TXN2 thioredoxin 2 1.4952
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 1.49242
ANGEL1 angel homolog 1 (Drosophila) 1.49092
MTFR1 mitochondrial fission regulator 1 1.48748
NSFL1C NSFL1 (p97) cofactor (p47) 1.48732
POLR3B polymerase (RNA) III (DNA directed) polypeptide B 1.48572
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 1.48572
PRMT5 protein arginine methyltransferase 5 1.48457
GUCA1B guanylate cyclase activator 1B (retina) 1.48078
AMPD1 adenosine monophosphate deaminase 1 1.47784
EIF3B eukaryotic translation initiation factor 3, subunit B 1.47747
PKNOX2 PBX/knotted 1 homeobox 2 1.47444
AFG3L2 AFG3-like AAA ATPase 2 1.47296
NECAB3 N-terminal EF-hand calcium binding protein 3 1.47276
TMEM131 transmembrane protein 131 1.47198
G6PC3 glucose 6 phosphatase, catalytic, 3 1.47041
C9ORF16 chromosome 9 open reading frame 16 1.46991
SETD5 SET domain containing 5 1.46779
CNOT4 CCR4-NOT transcription complex, subunit 4 1.4635
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 1.46325
MYO5C myosin VC 1.45938
H2AFY H2A histone family, member Y 1.45643
TOR1A torsin family 1, member A (torsin A) 1.45548
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 1.45088
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.44935
LETMD1 LETM1 domain containing 1 1.44775
AATF apoptosis antagonizing transcription factor 1.4475
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 1.44731
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 1.44686
CARM1 coactivator-associated arginine methyltransferase 1 1.44549
CYB5A cytochrome b5 type A (microsomal) 1.44304
GAK cyclin G associated kinase 1.44228
DMXL2 Dmx-like 2 1.4393
BBS1 Bardet-Biedl syndrome 1 1.43907
TAZ tafazzin 1.43861
ERGIC3 ERGIC and golgi 3 1.43854
RFX7 regulatory factor X, 7 1.43775
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 1.43712
EIF3I eukaryotic translation initiation factor 3, subunit I 1.43599
PCCB propionyl CoA carboxylase, beta polypeptide 1.43577
ABHD4 abhydrolase domain containing 4 1.43546
C7ORF49 chromosome 7 open reading frame 49 1.435
PINK1 PTEN induced putative kinase 1 1.43416
ZNF32 zinc finger protein 32 1.43227
MRPL15 mitochondrial ribosomal protein L15 1.42862
TMEM14B transmembrane protein 14B 1.42839
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 1.4278
TRAPPC6A trafficking protein particle complex 6A 1.42653
ILF3 interleukin enhancer binding factor 3, 90kDa 1.4251
BOLA1 bolA family member 1 1.4227
SIRT2 sirtuin 2 1.42253
MPI mannose phosphate isomerase 1.42136
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 1.42091

decreased expression

Symbol Name Standardized Value
CD59 CD59 molecule, complement regulatory protein -4.04052
GCH1 GTP cyclohydrolase 1 -3.64408
CALM1 calmodulin 1 (phosphorylase kinase, delta) -3.55132
PTGES3 prostaglandin E synthase 3 (cytosolic) -3.27299
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -3.10083
SON SON DNA binding protein -3.07325
RABGAP1L RAB GTPase activating protein 1-like -3.05934
RNF114 ring finger protein 114 -3.04858
HMGB1 high mobility group box 1 -2.90284
RBBP7 retinoblastoma binding protein 7 -2.89194
CHN1 chimerin 1 -2.87052
KLHL2 kelch-like family member 2 -2.81887
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 -2.8001
ZNF350 zinc finger protein 350 -2.79142
PHIP pleckstrin homology domain interacting protein -2.75208
CFLAR CASP8 and FADD-like apoptosis regulator -2.6681
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -2.65277
CLINT1 clathrin interactor 1 -2.63745
EVI2B ecotropic viral integration site 2B -2.60947
FAM45A family with sequence similarity 45, member A -2.60302
PRPF38B pre-mRNA processing factor 38B -2.56601
TROVE2 TROVE domain family, member 2 -2.51641
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 -2.48707
GBP2 guanylate binding protein 2, interferon-inducible -2.48423
CDK11A cyclin-dependent kinase 11A -2.47344
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa -2.46319
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -2.44945
DCLRE1C DNA cross-link repair 1C -2.37561
TNPO3 transportin 3 -2.36636
TRAV8-3 T cell receptor alpha variable 8-3 -2.34354
BUB3 BUB3 mitotic checkpoint protein -2.32606
MT1X metallothionein 1X -2.30233
C1ORF174 chromosome 1 open reading frame 174 -2.29229
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -2.29076
CMC2 C-x(9)-C motif containing 2 -2.27866
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.23987
FAM21A family with sequence similarity 21, member A -2.23933
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -2.23434
MED13 mediator complex subunit 13 -2.20106
TGFBR3 transforming growth factor, beta receptor III -2.19611
ZNF292 zinc finger protein 292 -2.18513
KIAA0430 KIAA0430 -2.18202
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -2.17229
KIF3A kinesin family member 3A -2.16401
SCAF11 SR-related CTD-associated factor 11 -2.15938
NRBP1 nuclear receptor binding protein 1 -2.13611
ZDHHC6 zinc finger, DHHC-type containing 6 -2.13249
LAX1 lymphocyte transmembrane adaptor 1 -2.11753
TMEM87A transmembrane protein 87A -2.11353
TBK1 TANK-binding kinase 1 -2.11223
SNURF SNRPN upstream reading frame -2.08664
SUSD6 sushi domain containing 6 -2.07799
KAT2B K(lysine) acetyltransferase 2B -2.07557
LMBRD1 LMBR1 domain containing 1 -2.07015
CNOT2 CCR4-NOT transcription complex, subunit 2 -2.06626
MGEA5 meningioma expressed antigen 5 (hyaluronidase) -2.05715
CASP4 caspase 4, apoptosis-related cysteine peptidase -2.05429
CLEC2B C-type lectin domain family 2, member B -2.05201
GMFG glia maturation factor, gamma -2.04651
ARF6 ADP-ribosylation factor 6 -2.0432
PHF11 PHD finger protein 11 -2.042
GNB5 guanine nucleotide binding protein (G protein), beta 5 -2.01963
KRAS Kirsten rat sarcoma viral oncogene homolog -2.01223
FAM32A family with sequence similarity 32, member A -2.00668
TRIP11 thyroid hormone receptor interactor 11 -1.98995
FAM21C family with sequence similarity 21, member C -1.98836
CYLD cylindromatosis (turban tumor syndrome) -1.97673
MBP myelin basic protein -1.97072
SET SET nuclear proto-oncogene -1.96561
PNRC2 proline-rich nuclear receptor coactivator 2 -1.96296
RSBN1 round spermatid basic protein 1 -1.95603
TMEM59 transmembrane protein 59 -1.9559
OFD1 oral-facial-digital syndrome 1 -1.9444
TRAPPC10 trafficking protein particle complex 10 -1.94405
MKRN1 makorin ring finger protein 1 -1.93804
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -1.92949
FYN FYN proto-oncogene, Src family tyrosine kinase -1.91915
ACSL3 acyl-CoA synthetase long-chain family member 3 -1.91341
SAV1 salvador family WW domain containing protein 1 -1.90578
TTC36 tetratricopeptide repeat domain 36 -1.90427
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -1.89861
RAD17 RAD17 homolog (S. pombe) -1.89809
RNF4 ring finger protein 4 -1.89079
MSL3 male-specific lethal 3 homolog (Drosophila) -1.8869
PGRMC1 progesterone receptor membrane component 1 -1.88305
CALM2 calmodulin 2 (phosphorylase kinase, delta) -1.88007
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.87915
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -1.87805
TRAPPC4 trafficking protein particle complex 4 -1.87533
MALT1 MALT1 paracaspase -1.872
CUL2 cullin 2 -1.86867
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) -1.86776
VEZF1 vascular endothelial zinc finger 1 -1.86758
CCDC28A coiled-coil domain containing 28A -1.85592
ANXA7 annexin A7 -1.85587
THAP11 THAP domain containing 11 -1.8489
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) -1.84664
YME1L1 YME1-like 1 ATPase -1.84319
C9ORF78 chromosome 9 open reading frame 78 -1.83735
NTAN1 N-terminal asparagine amidase -1.83693
SOCS5 suppressor of cytokine signaling 5 -1.83178
TRPC1 transient receptor potential cation channel, subfamily C, member 1 -1.82879
FUBP1 far upstream element (FUSE) binding protein 1 -1.82476
THUMPD1 THUMP domain containing 1 -1.81498
FBXO7 F-box protein 7 -1.81018
H2AFZ H2A histone family, member Z -1.80051
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -1.79718
COIL coilin -1.79217
ZNF24 zinc finger protein 24 -1.78738
IMP3 IMP3, U3 small nucleolar ribonucleoprotein -1.78614
WSB2 WD repeat and SOCS box containing 2 -1.7819
PNMA1 paraneoplastic Ma antigen 1 -1.78134
ANKRD12 ankyrin repeat domain 12 -1.77954
TCAF1 TRPM8 channel-associated factor 1 -1.77785
MPC1 mitochondrial pyruvate carrier 1 -1.77067
PIKFYVE phosphoinositide kinase, FYVE finger containing -1.76997
AKIRIN1 akirin 1 -1.76943
DPP8 dipeptidyl-peptidase 8 -1.7692
HLA-E major histocompatibility complex, class I, E -1.76468
RAB35 RAB35, member RAS oncogene family -1.74015
PRPF3 pre-mRNA processing factor 3 -1.73975
SERINC1 serine incorporator 1 -1.73964
ITK IL2-inducible T-cell kinase -1.7395
MBD4 methyl-CpG binding domain protein 4 -1.73045
ATG5 autophagy related 5 -1.72424
WDR37 WD repeat domain 37 -1.71644
CCL5 chemokine (C-C motif) ligand 5 -1.71634
BTD biotinidase -1.71338
SECISBP2 SECIS binding protein 2 -1.70707
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -1.70415
PPAP2A phosphatidic acid phosphatase type 2A -1.70057
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -1.69976
MOB1A MOB kinase activator 1A -1.69904
LPIN1 lipin 1 -1.69471
GMEB1 glucocorticoid modulatory element binding protein 1 -1.6929
ARRB1 arrestin, beta 1 -1.6887
UBE2N ubiquitin-conjugating enzyme E2N -1.67909
PCF11 PCF11 cleavage and polyadenylation factor subunit -1.6761
CNOT7 CCR4-NOT transcription complex, subunit 7 -1.67606
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -1.67513
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -1.65866
AIP aryl hydrocarbon receptor interacting protein -1.6582
SRP19 signal recognition particle 19kDa -1.65791
ANKRD49 ankyrin repeat domain 49 -1.65768
SEC23A Sec23 homolog A (S. cerevisiae) -1.65712
PGRMC2 progesterone receptor membrane component 2 -1.65559
CTR9 CTR9, Paf1/RNA polymerase II complex component -1.65552
RSRC1 arginine/serine-rich coiled-coil 1 -1.63939
USP1 ubiquitin specific peptidase 1 -1.63756
JAK1 Janus kinase 1 -1.63421
LGALS8 lectin, galactoside-binding, soluble, 8 -1.62251
ADAM17 ADAM metallopeptidase domain 17 -1.61903
DUSP12 dual specificity phosphatase 12 -1.61705
TPR translocated promoter region, nuclear basket protein -1.60977
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -1.60778
GALC galactosylceramidase -1.60567
GOLGA8H golgin A8 family, member H -1.60563
EIF3A eukaryotic translation initiation factor 3, subunit A -1.6044
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -1.60223
TSC1 tuberous sclerosis 1 -1.56361
ANKRD6 ankyrin repeat domain 6 -1.55715
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -1.5561
SNX2 sorting nexin 2 -1.55241
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa -1.54778
CNBP CCHC-type zinc finger, nucleic acid binding protein -1.54625
MT1F metallothionein 1F -1.54598
ZNF43 zinc finger protein 43 -1.54595
RIT1 Ras-like without CAAX 1 -1.54358
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -1.54354
PSME4 proteasome (prosome, macropain) activator subunit 4 -1.54132
ZBED5 zinc finger, BED-type containing 5 -1.53937
STK24 serine/threonine kinase 24 -1.53862
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 -1.53148
RFC5 replication factor C (activator 1) 5, 36.5kDa -1.52408
RANBP6 RAN binding protein 6 -1.52319
HECA headcase homolog (Drosophila) -1.51775
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa -1.51705
CIB1 calcium and integrin binding 1 (calmyrin) -1.51251
TIGAR TP53 induced glycolysis regulatory phosphatase -1.51063
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 -1.50993
CLSTN1 calsyntenin 1 -1.50864
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria -1.5075
CDC14B cell division cycle 14B -1.50339
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -1.50245
CD84 CD84 molecule -1.49734
FDX1 ferredoxin 1 -1.49483
PARP12 poly (ADP-ribose) polymerase family, member 12 -1.49289
SRSF7 serine/arginine-rich splicing factor 7 -1.48735
SELT selenoprotein T -1.48732
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -1.4838
CUTC cutC copper transporter -1.48127
ANAPC5 anaphase promoting complex subunit 5 -1.47817
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -1.47777
HTRA2 HtrA serine peptidase 2 -1.47699
WIPF2 WAS/WASL interacting protein family, member 2 -1.47665
PNISR PNN-interacting serine/arginine-rich protein -1.47035
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 -1.46855
RDX radixin -1.4676
ACAT1 acetyl-CoA acetyltransferase 1 -1.46604
DYNLT3 dynein, light chain, Tctex-type 3 -1.45936
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) -1.45406
ADAR adenosine deaminase, RNA-specific -1.45075
UBXN7 UBX domain protein 7 -1.44894
LUZP1 leucine zipper protein 1 -1.4483
DDB2 damage-specific DNA binding protein 2, 48kDa -1.44677
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -1.44419
HOPX HOP homeobox -1.44257
PPIA peptidylprolyl isomerase A (cyclophilin A) -1.43857
THAP7 THAP domain containing 7 -1.43778
WAC WW domain containing adaptor with coiled-coil -1.43208
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 -1.43168
AIM1 absent in melanoma 1 -1.42569
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 -1.42449
UBE2G1 ubiquitin-conjugating enzyme E2G 1 -1.42395
TMEM127 transmembrane protein 127 -1.42271
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 -1.42236
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -1.42192
PCM1 pericentriolar material 1 -1.42104
SERF1B small EDRK-rich factor 1B (centromeric) -1.42084
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -1.41382
TCP1 t-complex 1 -1.41324
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2 -1.4108
TAPBP TAP binding protein (tapasin) -1.41073
LYRM1 LYR motif containing 1 -1.40967
PHF10 PHD finger protein 10 -1.40711
COX5B cytochrome c oxidase subunit Vb -1.40549
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.40107
BECN1 beclin 1, autophagy related -1.39981
ADRB2 adrenoceptor beta 2, surface -1.39949
C6ORF120 chromosome 6 open reading frame 120 -1.39804
TMEM50A transmembrane protein 50A -1.39494
PAM peptidylglycine alpha-amidating monooxygenase -1.39323
STX8 syntaxin 8 -1.38749
TMEM109 transmembrane protein 109 -1.38686
EED embryonic ectoderm development -1.38067
CUL5 cullin 5 -1.37697
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 -1.37544
SNX6 sorting nexin 6 -1.37482
CRTAM cytotoxic and regulatory T cell molecule -1.37414
KPNA6 karyopherin alpha 6 (importin alpha 7) -1.37154
MORC3 MORC family CW-type zinc finger 3 -1.37123
RRAGA Ras-related GTP binding A -1.36717
MED17 mediator complex subunit 17 -1.36378
DERL2 derlin 2 -1.36045
SRSF9 serine/arginine-rich splicing factor 9 -1.36007
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -1.35725
SDF2 stromal cell-derived factor 2 -1.35593
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa -1.3558
SREK1IP1 SREK1-interacting protein 1 -1.35464
N4BP2L2 NEDD4 binding protein 2-like 2 -1.35456
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -1.35409
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -1.35389
C12ORF29 chromosome 12 open reading frame 29 -1.35235
C14ORF169 chromosome 14 open reading frame 169 -1.35195
ENO2 enolase 2 (gamma, neuronal) -1.35109
RNF25 ring finger protein 25 -1.35071
TBX21 T-box 21 -1.34969
NUP205 nucleoporin 205kDa -1.34844
KDM6A lysine (K)-specific demethylase 6A -1.34764
C1ORF50 chromosome 1 open reading frame 50 -1.34195
LAPTM4A lysosomal protein transmembrane 4 alpha -1.34168
ISCU iron-sulfur cluster assembly enzyme -1.34044
APOL6 apolipoprotein L, 6 -1.33886
PNRC1 proline-rich nuclear receptor coactivator 1 -1.33857
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa -1.33545
TULP4 tubby like protein 4 -1.3296
ZBTB38 zinc finger and BTB domain containing 38 -1.32847
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 -1.32565
SYT11 synaptotagmin XI -1.3251
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -1.32227
ZMPSTE24 zinc metallopeptidase STE24 -1.3169
MAN2A1 mannosidase, alpha, class 2A, member 1 -1.31628
USP15 ubiquitin specific peptidase 15 -1.31567
RPS27L ribosomal protein S27-like -1.31359
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -1.3123
AES amino-terminal enhancer of split -1.31152
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -1.31091
RNF113A ring finger protein 113A -1.30899
PEX26 peroxisomal biogenesis factor 26 -1.30872
CDV3 CDV3 homolog (mouse) -1.30631
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 -1.30474
ZBED1 zinc finger, BED-type containing 1 -1.30428
GZMK granzyme K (granzyme 3; tryptase II) -1.30281
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 -1.30177
UFL1 UFM1-specific ligase 1 -1.29917
FCHSD2 FCH and double SH3 domains 2 -1.29878
ZNF506 zinc finger protein 506 -1.29727
WDR55 WD repeat domain 55 -1.29537
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 -1.28987
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -1.28537
PPP6C protein phosphatase 6, catalytic subunit -1.27906
TRDV3 T cell receptor delta variable 3 -1.27638
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma -1.27549
PIAS1 protein inhibitor of activated STAT, 1 -1.27319
MT2A metallothionein 2A -1.27318
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa -1.26733
RAP1B RAP1B, member of RAS oncogene family -1.26731
CD6 CD6 molecule -1.26603
SMYD2 SET and MYND domain containing 2 -1.26558
IL2RB interleukin 2 receptor, beta -1.2654