Laryngeal Neoplasms Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

114 genes associated with the Laryngeal Neoplasms phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AHR aryl hydrocarbon receptor
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANKK1 ankyrin repeat and kinase domain containing 1
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
BCL2 B-cell CLL/lymphoma 2
CAPN10 calpain 10
CCND1 cyclin D1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CHEK2 checkpoint kinase 2
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLPTM1L CLPTM1-like
COMT catechol-O-methyltransferase
CTNNA2 catenin (cadherin-associated protein), alpha 2
CTNNA3 catenin (cadherin-associated protein), alpha 3
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DEC1 deleted in esophageal cancer 1
DLEC1 deleted in lung and esophageal cancer 1
DRD2 dopamine receptor D2
EGFR epidermal growth factor receptor
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
ERCC6 excision repair cross-complementation group 6
FANCG Fanconi anemia, complementation group G
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FHIT fragile histidine triad
GJB5 gap junction protein, beta 5, 31.1kDa
GNAS GNAS complex locus
GSTA2 glutathione S-transferase alpha 2
GSTM1 glutathione S-transferase mu 1
GSTM3 glutathione S-transferase mu 3 (brain)
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HYKK hydroxylysine kinase
IL10 interleukin 10
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL6 interleukin 6
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM4C lysine (K)-specific demethylase 4C
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LIG3 ligase III, DNA, ATP-dependent
LTBP1 latent transforming growth factor beta binding protein 1
LZTS1 leucine zipper, putative tumor suppressor 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGMT O-6-methylguanine-DNA methyltransferase
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MPO myeloperoxidase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MUS81 MUS81 structure-specific endonuclease subunit
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NBN nibrin
NQO1 NAD(P)H dehydrogenase, quinone 1
OGG1 8-oxoguanine DNA glycosylase
PCNA proliferating cell nuclear antigen
POLB polymerase (DNA directed), beta
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAD23B RAD23 homolog B (S. cerevisiae)
RAD50 RAD50 homolog (S. cerevisiae)
RECQL5 RecQ protein-like 5
SOD2 superoxide dismutase 2, mitochondrial
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNF tumor necrosis factor
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TP53 tumor protein p53
TYMS thymidylate synthetase
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
VEGFA vascular endothelial growth factor A
WRAP53 WD repeat containing, antisense to TP53
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3