LY-294002-6953 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the LY-294002-6953 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADARB1 adenosine deaminase, RNA-specific, B1
ADCK3 aarF domain containing kinase 3
ADGRE3 adhesion G protein-coupled receptor E3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AMH anti-Mullerian hormone
ASPHD1 aspartate beta-hydroxylase domain containing 1
BCL6 B-cell CLL/lymphoma 6
BRD1 bromodomain containing 1
BTD biotinidase
BTG1 B-cell translocation gene 1, anti-proliferative
C14ORF93 chromosome 14 open reading frame 93
C21ORF91 chromosome 21 open reading frame 91
CALCOCO1 calcium binding and coiled-coil domain 1
CALHM2 calcium homeostasis modulator 2
CCDC25 coiled-coil domain containing 25
CCDC28A coiled-coil domain containing 28A
CCNG2 cyclin G2
CDK12 cyclin-dependent kinase 12
CDON cell adhesion associated, oncogene regulated
CFLAR CASP8 and FADD-like apoptosis regulator
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
COL5A1 collagen, type V, alpha 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DEPTOR DEP domain containing MTOR-interacting protein
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DRD2 dopamine receptor D2
DUSP10 dual specificity phosphatase 10
EGR1 early growth response 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GLS glutaminase
GMPR guanosine monophosphate reductase
GPR1 G protein-coupled receptor 1
GRIK5 glutamate receptor, ionotropic, kainate 5
HAUS5 HAUS augmin-like complex, subunit 5
HBP1 HMG-box transcription factor 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2AE histone cluster 1, H2ae
HIST1H2AG histone cluster 1, H2ag
HIST1H2BD histone cluster 1, H2bd
HIST1H2BG histone cluster 1, H2bg
HIST1H2BH histone cluster 1, H2bh
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HIST1H3H histone cluster 1, H3h
HIST2H2BE histone cluster 2, H2be
HLA-E major histocompatibility complex, class I, E
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
IGLJ3 immunoglobulin lambda joining 3
ING4 inhibitor of growth family, member 4
IRS2 insulin receptor substrate 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KIAA0319L KIAA0319-like
KLF5 Kruppel-like factor 5 (intestinal)
KLHL24 kelch-like family member 24
KRT33A keratin 33A, type I
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC157562 uncharacterized LOC157562
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MNT MAX network transcriptional repressor
MXD4 MAX dimerization protein 4
MYOF myoferlin
N4BP2L2 NEDD4 binding protein 2-like 2
NDE1 nudE neurodevelopment protein 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NIPAL3 NIPA-like domain containing 3
PCLO piccolo presynaptic cytomatrix protein
PDE4DIP phosphodiesterase 4D interacting protein
PNRC1 proline-rich nuclear receptor coactivator 1
PPAP2B phosphatidic acid phosphatase type 2B
RCAN3 RCAN family member 3
RGS10 regulator of G-protein signaling 10
RNF19B ring finger protein 19B
RPL23AP32 ribosomal protein L23a pseudogene 32
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SIX2 SIX homeobox 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SPTBN1 spectrin, beta, non-erythrocytic 1
SYNJ2 synaptojanin 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
YPEL1 yippee-like 1 (Drosophila)
ZNF204P zinc finger protein 204, pseudogene
ZNF211 zinc finger protein 211
ZNF292 zinc finger protein 292
ZNF318 zinc finger protein 318
ZNF44 zinc finger protein 44
ZNF510 zinc finger protein 510
ZNF79 zinc finger protein 79
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACKR3 atypical chemokine receptor 3
ADORA2B adenosine A2b receptor
APIP APAF1 interacting protein
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARMC6 armadillo repeat containing 6
ASTE1 asteroid homolog 1 (Drosophila)
ATAD3A ATPase family, AAA domain containing 3A
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
C16ORF59 chromosome 16 open reading frame 59
C1ORF106 chromosome 1 open reading frame 106
C2CD2 C2 calcium-dependent domain containing 2
C9ORF91 chromosome 9 open reading frame 91
CA2 carbonic anhydrase II
CLDN9 claudin 9
COA7 cytochrome c oxidase assembly factor 7 (putative)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DOLK dolichol kinase
EGR3 early growth response 3
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERCC5 excision repair cross-complementation group 5
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC5 exocyst complex component 5
EXOSC9 exosome component 9
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAIM Fas apoptotic inhibitory molecule
FJX1 four jointed box 1 (Drosophila)
GFOD1 glucose-fructose oxidoreductase domain containing 1
GINS1 GINS complex subunit 1 (Psf1 homolog)
GLB1L2 galactosidase, beta 1-like 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GRWD1 glutamate-rich WD repeat containing 1
HEATR3 HEAT repeat containing 3
HMOX1 heme oxygenase 1
HOXC11 homeobox C11
HPS5 Hermansky-Pudlak syndrome 5
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA4L heat shock 70kDa protein 4-like
IPP intracisternal A particle-promoted polypeptide
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIAA0753 KIAA0753
KIN Kin17 DNA and RNA binding protein
LACTB2 lactamase, beta 2
LAMA3 laminin, alpha 3
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MANEA mannosidase, endo-alpha
MAP7D1 MAP7 domain containing 1
MCM10 minichromosome maintenance complex component 10
MYD88 myeloid differentiation primary response 88
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NFS1 NFS1 cysteine desulfurase
NUAK1 NUAK family, SNF1-like kinase, 1
NUP85 nucleoporin 85kDa
ORC1 origin recognition complex, subunit 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PACS1 phosphofurin acidic cluster sorting protein 1
PHF10 PHD finger protein 10
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRR15L proline rich 15-like
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAI14 retinoic acid induced 14
RANBP17 RAN binding protein 17
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RGS16 regulator of G-protein signaling 16
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SFN stratifin
SLC16A6 solute carrier family 16, member 6
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPAG1 sperm associated antigen 1
SPC25 SPC25, NDC80 kinetochore complex component
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYNGR3 synaptogyrin 3
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TGFB3 transforming growth factor, beta 3
TGIF2 TGFB-induced factor homeobox 2
TIPIN TIMELESS interacting protein
TMEM104 transmembrane protein 104
TMEM168 transmembrane protein 168
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TTC27 tetratricopeptide repeat domain 27
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
ZDHHC6 zinc finger, DHHC-type containing 6
ZIC1 Zic family member 1
ZNF107 zinc finger protein 107
ZNF165 zinc finger protein 165
ZNF232 zinc finger protein 232
ZNF268 zinc finger protein 268
ZNF692 zinc finger protein 692