| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the LY-294002-6186 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ACACB | acetyl-CoA carboxylase beta |
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ADAM3A | ADAM metallopeptidase domain 3A (pseudogene) |
| ADCYAP1R1 | adenylate cyclase activating polypeptide 1 (pituitary) receptor type I |
| AQP9 | aquaporin 9 |
| ATN1 | atrophin 1 |
| AURKA | aurora kinase A |
| BAIAP2 | BAI1-associated protein 2 |
| BAIAP3 | BAI1-associated protein 3 |
| BRS3 | bombesin-like receptor 3 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CHGB | chromogranin B |
| CKM | creatine kinase, muscle |
| DAPK3 | death-associated protein kinase 3 |
| DICER1 | dicer 1, ribonuclease type III |
| DLG1 | discs, large homolog 1 (Drosophila) |
| DNMT3L | DNA (cytosine-5-)-methyltransferase 3-like |
| EED | embryonic ectoderm development |
| EPS8L3 | EPS8-like 3 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FBXO31 | F-box protein 31 |
| FGF16 | fibroblast growth factor 16 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GIMAP4 | GTPase, IMAP family member 4 |
| GLRA3 | glycine receptor, alpha 3 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTPBP1 | GTP binding protein 1 |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H2BH | histone cluster 1, H2bh |
| HIST1H3H | histone cluster 1, H3h |
| HOMER2 | homer scaffolding protein 2 |
| IL15RA | interleukin 15 receptor, alpha |
| KCNH1 | potassium channel, voltage gated eag related subfamily H, member 1 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| LILRA5 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MLXIP | MLX interacting protein |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MUC13 | mucin 13, cell surface associated |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NF2 | neurofibromin 2 (merlin) |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NIPAL2 | NIPA-like domain containing 2 |
| NNAT | neuronatin |
| OLFML2B | olfactomedin-like 2B |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCLO | piccolo presynaptic cytomatrix protein |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PKP3 | plakophilin 3 |
| PLD2 | phospholipase D2 |
| PLD3 | phospholipase D family, member 3 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha |
| RAB13 | RAB13, member RAS oncogene family |
| RGS5 | regulator of G-protein signaling 5 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPL7 | ribosomal protein L7 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SERHL2 | serine hydrolase-like 2 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SLC22A17 | solute carrier family 22, member 17 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
| SOX10 | SRY (sex determining region Y)-box 10 |
| STK17A | serine/threonine kinase 17a |
| TEF | thyrotrophic embryonic factor |
| TEK | TEK tyrosine kinase, endothelial |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
| TRIM10 | tripartite motif containing 10 |
| TRIM23 | tripartite motif containing 23 |
| TRIM36 | tripartite motif containing 36 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF132 | zinc finger protein 132 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| ADORA3 | adenosine A3 receptor |
| ANKRD55 | ankyrin repeat domain 55 |
| ANXA3 | annexin A3 |
| ARRB1 | arrestin, beta 1 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| C5 | complement component 5 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 |
| CBS | cystathionine-beta-synthase |
| CCDC86 | coiled-coil domain containing 86 |
| CCDC88C | coiled-coil domain containing 88C |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCNA1 | cyclin A1 |
| CD69 | CD69 molecule |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CTH | cystathionine gamma-lyase |
| CTSG | cathepsin G |
| CUX2 | cut-like homeobox 2 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDN | dendrin |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DIXDC1 | DIX domain containing 1 |
| ECM1 | extracellular matrix protein 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FPGS | folylpolyglutamate synthase |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| HP | haptoglobin |
| IL1R2 | interleukin 1 receptor, type II |
| JMJD4 | jumonji domain containing 4 |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KIAA1024 | KIAA1024 |
| KIF21B | kinesin family member 21B |
| KLF11 | Kruppel-like factor 11 |
| KLHL26 | kelch-like family member 26 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LIN7A | lin-7 homolog A (C. elegans) |
| MDN1 | MDN1, midasin homolog (yeast) |
| MON1B | MON1 secretory trafficking family member B |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NBEAL2 | neurobeachin-like 2 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| ORM1 | orosomucoid 1 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PDZD7 | PDZ domain containing 7 |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| POMZP3 | POM121 and ZP3 fusion |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PSAT1 | phosphoserine aminotransferase 1 |
| PUS7 | pseudouridylate synthase 7 (putative) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS13 | regulator of G-protein signaling 13 |
| RGS16 | regulator of G-protein signaling 16 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RNF122 | ring finger protein 122 |
| S100P | S100 calcium binding protein P |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SIGLEC9 | sialic acid binding Ig-like lectin 9 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
| STC2 | stanniocalcin 2 |
| TERT | telomerase reverse transcriptase |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TGM5 | transglutaminase 5 |
| THBS4 | thrombospondin 4 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TRIB3 | tribbles pseudokinase 3 |
| UPK3A | uroplakin 3A |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| VN1R1 | vomeronasal 1 receptor 1 |
| WDR3 | WD repeat domain 3 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF354A | zinc finger protein 354A |
