LU-99A Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

353 genes with high or low expression in LU-99A relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
PXN paxillin 3.60177
DENR density-regulated protein 3.3824
DIABLO diablo, IAP-binding mitochondrial protein 3.33963
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 3.26533
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 3.20913
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 3.1692
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 2.93428
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 2.9082
INVS inversin 2.72227
SBNO1 strawberry notch homolog 1 (Drosophila) 2.67134
OASL 2'-5'-oligoadenylate synthetase-like 2.65753
ASB1 ankyrin repeat and SOCS box containing 1 2.62595
TRIM21 tripartite motif containing 21 2.59323
CAPRIN2 caprin family member 2 2.56729
CLIP1 CAP-GLY domain containing linker protein 1 2.5262
ZCCHC8 zinc finger, CCHC domain containing 8 2.52227
TTC1 tetratricopeptide repeat domain 1 2.49583
ESM1 endothelial cell-specific molecule 1 2.37329
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 2.35664
PITRM1 pitrilysin metallopeptidase 1 2.35237
ANAPC5 anaphase promoting complex subunit 5 2.33241
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12) 2.31147
RNF10 ring finger protein 10 2.28601
RAB35 RAB35, member RAS oncogene family 2.28256
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 2.24815
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 2.23963
HRK harakiri, BCL2 interacting protein 2.23788
IL13RA2 interleukin 13 receptor, alpha 2 2.21977
INTS8 integrator complex subunit 8 2.18781
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 2.17401
PAPPA2 pappalysin 2 2.16557
FKBP15 FK506 binding protein 15, 133kDa 2.16244
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.15516
NOSIP nitric oxide synthase interacting protein 2.14463
HMGA1 high mobility group AT-hook 1 2.11052
TSG101 tumor susceptibility 101 2.106
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.05379
GSPT2 G1 to S phase transition 2 2.02536
HSPA4 heat shock 70kDa protein 4 2.02064
SENP6 SUMO1/sentrin specific peptidase 6 2.01377
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 1.99317
TP53BP1 tumor protein p53 binding protein 1 1.97217
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 1.95634
RTN4 reticulon 4 1.94728
MTMR11 myotubularin related protein 11 1.94342
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 1.93514
IRF7 interferon regulatory factor 7 1.93161
MRPS10 mitochondrial ribosomal protein S10 1.92374
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 1.90893
SIRT5 sirtuin 5 1.90553
ARHGAP24 Rho GTPase activating protein 24 1.8953
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 1.88672
FGF5 fibroblast growth factor 5 1.8767
EDF1 endothelial differentiation-related factor 1 1.87587
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 1.87048
SDCCAG8 serologically defined colon cancer antigen 8 1.86725
NCOR2 nuclear receptor corepressor 2 1.85856
USP18 ubiquitin specific peptidase 18 1.84601
NTSR1 neurotensin receptor 1 (high affinity) 1.84152
MMP1 matrix metallopeptidase 1 1.84055
MRPS30 mitochondrial ribosomal protein S30 1.83969
WIPI2 WD repeat domain, phosphoinositide interacting 2 1.81515
HIP1R huntingtin interacting protein 1 related 1.81253
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 1.81253
THBD thrombomodulin 1.8123
KRT34 keratin 34, type I 1.80853
MRPS28 mitochondrial ribosomal protein S28 1.80402
WDR37 WD repeat domain 37 1.78279
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 1.78187
TMEM41B transmembrane protein 41B 1.76901
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 1.75984
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.75569
MTG1 mitochondrial ribosome-associated GTPase 1 1.75503
ADARB1 adenosine deaminase, RNA-specific, B1 1.74198
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 1.73529
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 1.73018
TRIM68 tripartite motif containing 68 1.72819
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 1.72609
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 1.72522
DNMBP dynamin binding protein 1.7236
BRD8 bromodomain containing 8 1.71383
PTGDS prostaglandin D2 synthase 21kDa (brain) 1.7138
RPP38 ribonuclease P/MRP 38kDa subunit 1.71329
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 1.7096
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 1.70336
IRF9 interferon regulatory factor 9 1.70229
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 1.70076
MED13L mediator complex subunit 13-like 1.7003
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 1.69491
FOXD1 forkhead box D1 1.68497
ERGIC2 ERGIC and golgi 2 1.66864
CCDC92 coiled-coil domain containing 92 1.66678
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) 1.64637
FGF2 fibroblast growth factor 2 (basic) 1.64363
CYTH2 cytohesin 2 1.63847
ANKHD1 ankyrin repeat and KH domain containing 1 1.63809
IAPP islet amyloid polypeptide 1.61835
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 1.61737
MGMT O-6-methylguanine-DNA methyltransferase 1.61608
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 1.6047
CCT4 chaperonin containing TCP1, subunit 4 (delta) 1.60435
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 1.59979
TUBGCP2 tubulin, gamma complex associated protein 2 1.59969
NME5 NME/NM23 family member 5 1.59475
WBP2 WW domain binding protein 2 1.59312
GTPBP2 GTP binding protein 2 1.5896
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 1.58489
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial 1.58292
CSF3 colony stimulating factor 3 (granulocyte) 1.57975
COQ6 coenzyme Q6 monooxygenase 1.57209
ENY2 enhancer of yellow 2 homolog (Drosophila) 1.56709
NOL7 nucleolar protein 7, 27kDa 1.56423
EHD4 EH-domain containing 4 1.55375
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 1.55315
IFI44L interferon-induced protein 44-like 1.55177
FOSL1 FOS-like antigen 1 1.54357
KIN Kin17 DNA and RNA binding protein 1.54217
TEX10 testis expressed 10 1.5418
ATG7 autophagy related 7 1.54095
AARS alanyl-tRNA synthetase 1.52935
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 1.52825
DYNLL1 dynein, light chain, LC8-type 1 1.52135
MX1 MX dynamin-like GTPase 1 1.51095
GDI2 GDP dissociation inhibitor 2 1.51032
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 1.50872
LHX1 LIM homeobox 1 1.50613
PUF60 poly-U binding splicing factor 60KDa 1.49953
FAM175B family with sequence similarity 175, member B 1.48114
RIOK2 RIO kinase 2 1.47614
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.46952
ATR ATR serine/threonine kinase 1.46863
BAG6 BCL2-associated athanogene 6 1.46588
SPANXC SPANX family, member C 1.46574
LRRC6 leucine rich repeat containing 6 1.46217
CEP170 centrosomal protein 170kDa 1.45925
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 1.45638
CCDC91 coiled-coil domain containing 91 1.45558
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 1.45347
SIRT6 sirtuin 6 1.45231
GTPBP4 GTP binding protein 4 1.45111
MCL1 myeloid cell leukemia 1 1.45056
CDCP1 CUB domain containing protein 1 1.44789
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 1.444
PPP1R26 protein phosphatase 1, regulatory subunit 26 1.43561
SQSTM1 sequestosome 1 1.43552
IPO7 importin 7 1.43392
PLSCR1 phospholipid scramblase 1 1.43044
UBE2B ubiquitin-conjugating enzyme E2B 1.42887
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.42713
KIAA0368 KIAA0368 1.42627
KDR kinase insert domain receptor 1.42604
SP100 SP100 nuclear antigen 1.42542
IFI44 interferon-induced protein 44 1.42538
PDGFA platelet-derived growth factor alpha polypeptide 1.41938

low expression

Symbol Name Standardized Value
GTF2I general transcription factor IIi -3.50711
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -3.14137
ZNF3 zinc finger protein 3 -3.00006
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 -2.58122
YLPM1 YLP motif containing 1 -2.52111
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene -2.51209
HILPDA hypoxia inducible lipid droplet-associated -2.47222
TRIM24 tripartite motif containing 24 -2.43762
UQCRC2 ubiquinol-cytochrome c reductase core protein II -2.38895
FASTK Fas-activated serine/threonine kinase -2.37844
PDIA4 protein disulfide isomerase family A, member 4 -2.36957
PDAP1 PDGFA associated protein 1 -2.3522
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -2.30519
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.26888
HMGN5 high mobility group nucleosome binding domain 5 -2.26432
OR7E37P olfactory receptor, family 7, subfamily E, member 37 pseudogene -2.26391
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -2.25578
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 -2.25447
PRELP proline/arginine-rich end leucine-rich repeat protein -2.24009
RFC2 replication factor C (activator 1) 2, 40kDa -2.23211
PHOX2A paired-like homeobox 2a -2.22603
AKAP9 A kinase (PRKA) anchor protein 9 -2.22505
PHTF2 putative homeodomain transcription factor 2 -2.21654
IRS4 insulin receptor substrate 4 -2.20766
PMS2P3 postmeiotic segregation increased 2 pseudogene 3 -2.2074
WAS Wiskott-Aldrich syndrome -2.20479
MYO1F myosin IF -2.17633
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) -2.17128
ZNF480 zinc finger protein 480 -2.13413
GUSB glucuronidase, beta -2.13375
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -2.09866
HIST1H2BL histone cluster 1, H2bl -2.09644
GP6 glycoprotein VI (platelet) -2.08389
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) -2.0606
MAPK10 mitogen-activated protein kinase 10 -2.05662
TMEM92 transmembrane protein 92 -2.05089
LMO7 LIM domain 7 -2.04363
BUD31 BUD31 homolog (S. cerevisiae) -2.03399
CASD1 CAS1 domain containing 1 -2.03357
AJAP1 adherens junctions associated protein 1 -2.03066
MKRN1 makorin ring finger protein 1 -2.02076
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 -2.00967
CLPS colipase, pancreatic -2.00758
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -2.00368
TGM4 transglutaminase 4 -1.99289
LUC7L2 LUC7-like 2 (S. cerevisiae) -1.98729
NEBL nebulette -1.98567
MAP3K8 mitogen-activated protein kinase kinase kinase 8 -1.97664
ADGRG2 adhesion G protein-coupled receptor G2 -1.97263
GPR85 G protein-coupled receptor 85 -1.96716
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 -1.9617
SND1 staphylococcal nuclease and tudor domain containing 1 -1.95905
PMS2P2 postmeiotic segregation increased 2 pseudogene 2 -1.95496
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 -1.94634
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -1.93498
RMI1 RecQ mediated genome instability 1 -1.91105
MDH2 malate dehydrogenase 2, NAD (mitochondrial) -1.89284
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -1.89202
EPS8L3 EPS8-like 3 -1.88921
WBSCR22 Williams Beuren syndrome chromosome region 22 -1.86562
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 -1.86286
NUP107 nucleoporin 107kDa -1.8601
COPS6 COP9 signalosome subunit 6 -1.84938
SYT12 synaptotagmin XII -1.84255
GCM1 glial cells missing homolog 1 (Drosophila) -1.83656
SRPK2 SRSF protein kinase 2 -1.83264
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 -1.81009
DDT D-dopachrome tautomerase -1.80699
ZNHIT1 zinc finger, HIT-type containing 1 -1.78502
NARFL nuclear prelamin A recognition factor-like -1.78428
SCRN3 secernin 3 -1.77642
PMEPA1 prostate transmembrane protein, androgen induced 1 -1.77333
PMS2P1 postmeiotic segregation increased 2 pseudogene 1 -1.76788
NPY6R neuropeptide Y receptor Y6 (pseudogene) -1.76341
MRPS33 mitochondrial ribosomal protein S33 -1.76293
ZNF668 zinc finger protein 668 -1.74431
LRRC17 leucine rich repeat containing 17 -1.74407
KRIT1 KRIT1, ankyrin repeat containing -1.74355
CD79A CD79a molecule, immunoglobulin-associated alpha -1.73844
ITK IL2-inducible T-cell kinase -1.73192
INSR insulin receptor -1.72818
APOLD1 apolipoprotein L domain containing 1 -1.71752
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 -1.71335
JMJD4 jumonji domain containing 4 -1.70871
TBL2 transducin (beta)-like 2 -1.70789
GAB1 GRB2-associated binding protein 1 -1.70279
CDKN2A cyclin-dependent kinase inhibitor 2A -1.70189
UBE3C ubiquitin protein ligase E3C -1.69431
KIAA1324 KIAA1324 -1.68697
GRTP1 growth hormone regulated TBC protein 1 -1.68628
AMBP alpha-1-microglobulin/bikunin precursor -1.68067
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled -1.67589
RAB11B RAB11B, member RAS oncogene family -1.66997
EEF1G eukaryotic translation elongation factor 1 gamma -1.66978
PRF1 perforin 1 (pore forming protein) -1.65358
ZNF117 zinc finger protein 117 -1.64989
PRKACG protein kinase, cAMP-dependent, catalytic, gamma -1.64395
CAMK2D calcium/calmodulin-dependent protein kinase II delta -1.64169
DGKQ diacylglycerol kinase, theta 110kDa -1.64
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog -1.63327
MRPS34 mitochondrial ribosomal protein S34 -1.63229
CRCP CGRP receptor component -1.62878
CDK5 cyclin-dependent kinase 5 -1.6266
ITGA9 integrin, alpha 9 -1.62493
IFNA2 interferon, alpha 2 -1.62329
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 -1.62251
TMEM80 transmembrane protein 80 -1.62039
RHEB Ras homolog enriched in brain -1.61761
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -1.60951
GLRX5 glutaredoxin 5 -1.60794
PYHIN1 pyrin and HIN domain family, member 1 -1.60459
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 -1.60351
POU3F4 POU class 3 homeobox 4 -1.59713
HOXA10 homeobox A10 -1.59688
ZBTB6 zinc finger and BTB domain containing 6 -1.59638
FMO3 flavin containing monooxygenase 3 -1.59223
CLDN11 claudin 11 -1.59119
UTRN utrophin -1.59053
INSIG1 insulin induced gene 1 -1.58496
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 -1.58156
AOAH acyloxyacyl hydrolase (neutrophil) -1.57776
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 -1.57664
SAG S-antigen; retina and pineal gland (arrestin) -1.57052
PRSS8 protease, serine, 8 -1.5656
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 -1.56499
HOOK2 hook microtubule-tethering protein 2 -1.56395
HADH hydroxyacyl-CoA dehydrogenase -1.56134
CCL22 chemokine (C-C motif) ligand 22 -1.55491
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -1.55397
UPK1B uroplakin 1B -1.54512
OVOL1 ovo-like zinc finger 1 -1.54376
TFF3 trefoil factor 3 (intestinal) -1.54302
NCALD neurocalcin delta -1.53535
DSG3 desmoglein 3 -1.5348
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 -1.5337
GZMK granzyme K (granzyme 3; tryptase II) -1.52614
ARRB2 arrestin, beta 2 -1.5243
TFRC transferrin receptor -1.5243
ORC5 origin recognition complex, subunit 5 -1.52339
VIP vasoactive intestinal peptide -1.52295
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4 -1.5203
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 -1.51946
CCK cholecystokinin -1.5185
WNT16 wingless-type MMTV integration site family, member 16 -1.51557
SOSTDC1 sclerostin domain containing 1 -1.51435
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide -1.51135
EFCAB1 EF-hand calcium binding domain 1 -1.50748
VTCN1 V-set domain containing T cell activation inhibitor 1 -1.5021
ADCK2 aarF domain containing kinase 2 -1.49929
TMPRSS5 transmembrane protease, serine 5 -1.49894
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 -1.49561
MEPCE methylphosphate capping enzyme -1.49166
RBM48 RNA binding motif protein 48 -1.49065
EMD emerin -1.49064
ING3 inhibitor of growth family, member 3 -1.49058
NEUROD4 neuronal differentiation 4 -1.48902
MMP3 matrix metallopeptidase 3 -1.48717
BCL7B B-cell CLL/lymphoma 7B -1.48473
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) -1.48332
USP2 ubiquitin specific peptidase 2 -1.479
CASP2 caspase 2, apoptosis-related cysteine peptidase -1.47772
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 -1.47765
BET1 Bet1 golgi vesicular membrane trafficking protein -1.47755
GJA4 gap junction protein, alpha 4, 37kDa -1.47598
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) -1.47546
FAM3C family with sequence similarity 3, member C -1.47457
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 -1.47091
TRRAP transformation/transcription domain-associated protein -1.46937
S100A1 S100 calcium binding protein A1 -1.46875
PCDH11X protocadherin 11 X-linked -1.46828
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 -1.46495
GPR75 G protein-coupled receptor 75 -1.46419
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -1.463
HIF3A hypoxia inducible factor 3, alpha subunit -1.46267
CRYGD crystallin, gamma D -1.45842
PHF14 PHD finger protein 14 -1.45679
OR2H2 olfactory receptor, family 2, subfamily H, member 2 -1.45646
RBBP4 retinoblastoma binding protein 4 -1.45477
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 -1.45432
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -1.45242
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -1.45209
CX3CL1 chemokine (C-X3-C motif) ligand 1 -1.44907
BCL2L10 BCL2-like 10 (apoptosis facilitator) -1.44718
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F -1.44286
CR1 complement component (3b/4b) receptor 1 (Knops blood group) -1.4414
THRAP3 thyroid hormone receptor associated protein 3 -1.44077
MYOZ3 myozenin 3 -1.44026
COL5A3 collagen, type V, alpha 3 -1.43961
MRS2 MRS2 magnesium transporter -1.4358
IGLL1 immunoglobulin lambda-like polypeptide 1 -1.43408
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -1.43122
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B -1.4309
KLK10 kallikrein-related peptidase 10 -1.42993
UBE2A ubiquitin-conjugating enzyme E2A -1.42726
SOD3 superoxide dismutase 3, extracellular -1.42702
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -1.42685
COL26A1 collagen, type XXVI, alpha 1 -1.42606
WRB tryptophan rich basic protein -1.42306
PPARA peroxisome proliferator-activated receptor alpha -1.41853