LU-135 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description A immortal human cell line cell that has the characteristics: Small cell carcinoma, variant type (Cell Line Ontology, CLO_0050030)
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Genes

129 genes with high or low copy number in LU-135 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa 3.12177
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 3.12177
MIR3192 microRNA 3192 3.12177
LINC00493 long intergenic non-protein coding RNA 493 3.12177
RBBP9 retinoblastoma binding protein 9 3.12177
SEC23B Sec23 homolog B (S. cerevisiae) 3.12177
BMP2 bone morphogenetic protein 2 2.93899
DZANK1 double zinc ribbon and ankyrin repeat domains 1 2.93899
OVOL2 ovo-like zinc finger 2 2.93899
NKX2-2 NK2 homeobox 2 2.93899
CRNKL1 crooked neck pre-mRNA splicing factor 1 2.93899
NKX2-4 NK2 homeobox 4 2.93899
LINC00851 long intergenic non-protein coding RNA 851 2.93899
LAMP5 lysosomal-associated membrane protein family, member 5 2.93899
HAO1 hydroxyacid oxidase (glycolate oxidase) 1 2.93899
TMX4 thioredoxin-related transmembrane protein 4 2.93899
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 2.76305
FERMT1 fermitin family member 1 2.76305
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 2.76305
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 2.76305
SNAP25 synaptosomal-associated protein, 25kDa 2.76305
SNX5 sorting nexin 5 2.76305
XRN2 5'-3' exoribonuclease 2 2.76305
TRMT6 tRNA methyltransferase 6 2.76305
CSRP2BP CSRP2 binding protein 2.76305
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 2.76305
PET117 PET117 homolog (S. cerevisiae) 2.76305
BTBD3 BTB (POZ) domain containing 3 2.76305
CHGB chromogranin B 2.76305
CRLS1 cardiolipin synthase 1 2.76305
C20ORF196 chromosome 20 open reading frame 196 2.76305
ZNF133 zinc finger protein 133 2.76305
INSM1 insulinoma-associated 1 2.76305
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans) 2.76305
SNORD17 small nucleolar RNA, C/D box 17 2.76305
LRRN4 leucine rich repeat neuronal 4 2.76305
MGME1 mitochondrial genome maintenance exonuclease 1 2.76305
MCM8 minichromosome maintenance complex component 8 2.76305
PCSK2 proprotein convertase subtilisin/kexin type 2 2.64759
BFSP1 beaded filament structural protein 1, filensin 2.64759
SNRPB2 small nuclear ribonucleoprotein polypeptide B 2.64759
ANKEF1 ankyrin repeat and EF-hand domain containing 1 2.64759
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 2.64759
SNAP25-AS1 SNAP25 antisense RNA 1 2.64759
ISM1-AS1 ISM1 antisense RNA 1 2.59653
ISM1 isthmin 1, angiogenesis inhibitor 2.59653
OTOR otoraplin 2.59653
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 2.59653
TASP1 taspase, threonine aspartase, 1 2.49065
GGTLC1 gamma-glutamyltransferase light chain 1 2.49065
CST5 cystatin D 2.49065
CST2 cystatin SA 2.44392
CST4 cystatin S 2.44392
CST9 cystatin 9 (testatin) 2.44392
CST1 cystatin SN 2.44392
CST3 cystatin C 2.44392
CST9L cystatin 9-like 2.44392
CST8 cystatin 8 (cystatin-related epididymal specific) 2.41451
CST13P cystatin 13, pseudogene 2.41451
NXT1 nuclear transport factor 2-like export factor 1 2.39327
NAPB N-ethylmaleimide-sensitive factor attachment protein, beta 2.39327
CST11 cystatin 11 2.39327
CSTL1 cystatin-like 1 2.39327
GZF1 GDNF-inducible zinc finger protein 1 2.39327
LOC100130298 hCG1816373-like 2.36889
CLVS1 clavesin 1 2.36889
ASPH aspartate beta-hydroxylase 2.35236
MIR4470 microRNA 4470 2.35236
SLC45A4 solute carrier family 45, member 4 2.30944
DENND3 DENN/MADD domain containing 3 2.25904
PTK2 protein tyrosine kinase 2 2.23324
DTD1 D-tyrosyl-tRNA deacylase 1 2.14116
LOC100130264 uncharacterized LOC100130264 2.14116
LOC100270804 uncharacterized LOC100270804 2.14116
SCP2D1 SCP2 sterol-binding domain containing 1 2.14116
LINC00652 long intergenic non-protein coding RNA 652 2.14116
C20ORF78 chromosome 20 open reading frame 78 2.14116
MACROD2-AS1 MACROD2 antisense RNA 1 2.13748
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 2.12703
PAX1 paired box 1 2.12703
RIN2 Ras and Rab interactor 2 2.12703
JAG1 jagged 1 2.12439
SLX4IP SLX4 interacting protein 2.12439
MKKS McKusick-Kaufman syndrome 2.12225
PLCB4 phospholipase C, beta 4 2.12225
LOC339593 uncharacterized LOC339593 2.12225
FLRT3 fibronectin leucine rich transmembrane protein 3 2.12225
KIF16B kinesin family member 16B 2.11167
BANF2 barrier to autointegration factor 2 2.11167
RRBP1 ribosome binding protein 1 2.11167
ACSS1 acyl-CoA synthetase short-chain family member 1 2.10992
APMAP adipocyte plasma membrane associated protein 2.10992
DSTN destrin (actin depolymerizing factor) 2.10992
VSX1 visual system homeobox 1 2.10992
FAM182B family with sequence similarity 182, member B 2.10992
CST7 cystatin F (leukocystatin) 2.10992
SYNDIG1 synapse differentiation inducing 1 2.10177
ABHD12 abhydrolase domain containing 12 2.10038
LOC284798 uncharacterized LOC284798 2.10038
NANP N-acetylneuraminic acid phosphatase 2.10038
PYGB phosphorylase, glycogen; brain 2.10038
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) 2.10038
GINS1 GINS complex subunit 1 (Psf1 homolog) 2.10038
NINL ninein-like 2.10038
ZNF337 zinc finger protein 337 2.10038
FLJ33581 uncharacterized LOC400839 2.09431
MACROD2 MACRO domain containing 2 2.09385
LOC284788 uncharacterized LOC284788 2.08781
LINC00261 long intergenic non-protein coding RNA 261 2.08712
SSTR4 somatostatin receptor 4 2.08712
THBD thrombomodulin 2.08712
CD93 CD93 molecule 2.08712
FOXA2 forkhead box A2 2.08712
LINC00656 long intergenic non-protein coding RNA 656 2.08712
CHD7 chromodomain helicase DNA binding protein 7 2.08021
MIR1204 microRNA 1204 2.04661
PVT1 Pvt1 oncogene (non-protein coding) 2.04585

low copy number

Symbol Name Standardized Value
MIR3179-2 microRNA 3179-2 -3.11641
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 -3.11641
NOMO3 NODAL modulator 3 -3.05196
MIR3180-3 microRNA 3180-3 -3.00044
GSTTP1 glutathione S-transferase theta pseudogene 1 -2.86117
OR52N5 olfactory receptor, family 52, subfamily N, member 5 -2.84224
LOC391322 D-dopachrome tautomerase-like -2.78432
GSTTP2 glutathione S-transferase theta pseudogene 2 -2.78432
GSTT1 glutathione S-transferase theta 1 -2.78432
CES1P1 carboxylesterase 1 pseudogene 1 -2.74485
OR52N1 olfactory receptor, family 52, subfamily N, member 1 -2.73524
BTNL3 butyrophilin-like 3 -2.72661