LGLL - Large granular lymphocytic leukemia_Peripheral blood mononuclear cell_GSE10631 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE10631
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Genes

600 genes differentially expressed during LGLL - Large granular lymphocytic leukemia_Peripheral blood mononuclear cell_GSE10631 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 2.76202
SFT2D2 SFT2 domain containing 2 2.61769
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 2.6065
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.59018
SON SON DNA binding protein 2.56133
C12ORF49 chromosome 12 open reading frame 49 2.55975
TMUB2 transmembrane and ubiquitin-like domain containing 2 2.52939
LYPLA2 lysophospholipase II 2.5124
CTBP1 C-terminal binding protein 1 2.48529
GPR153 G protein-coupled receptor 153 2.48434
PIAS3 protein inhibitor of activated STAT, 3 2.46167
RCN1 reticulocalbin 1, EF-hand calcium binding domain 2.46036
TXNL4B thioredoxin-like 4B 2.42723
RNASEH2B ribonuclease H2, subunit B 2.40591
CD81 CD81 molecule 2.37457
NEK3 NIMA-related kinase 3 2.36136
SEPT7 septin 7 2.34381
TPMT thiopurine S-methyltransferase 2.34168
CD63 CD63 molecule 2.32925
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 2.3096
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 2.27593
FICD FIC domain containing 2.25674
RBM25 RNA binding motif protein 25 2.24992
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 2.23553
ZNF710 zinc finger protein 710 2.23451
CNOT7 CCR4-NOT transcription complex, subunit 7 2.23151
MTDH metadherin 2.22839
MTF1 metal-regulatory transcription factor 1 2.21715
RAD17 RAD17 homolog (S. pombe) 2.21533
GOLGB1 golgin B1 2.21072
ARL1 ADP-ribosylation factor-like 1 2.19062
MRPS10 mitochondrial ribosomal protein S10 2.18049
PDS5B PDS5 cohesin associated factor B 2.17959
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 2.16849
SCLY selenocysteine lyase 2.16388
FAM35A family with sequence similarity 35, member A 2.15458
CLIP1 CAP-GLY domain containing linker protein 1 2.14339
CLASP1 cytoplasmic linker associated protein 1 2.12143
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 2.11823
PPP1R12A protein phosphatase 1, regulatory subunit 12A 2.11552
CAPN2 calpain 2, (m/II) large subunit 2.11145
EPS15 epidermal growth factor receptor pathway substrate 15 2.11118
PIGCP1 phosphatidylinositol glycan anchor biosynthesis, class C, pseudogene 1 2.10068
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 2.09206
ZCCHC6 zinc finger, CCHC domain containing 6 2.07883
TCP10L t-complex 10-like 2.07824
ERP44 endoplasmic reticulum protein 44 2.04944
KIAA0196 KIAA0196 2.0481
LYPLA1 lysophospholipase I 2.04701
RAB11FIP5 RAB11 family interacting protein 5 (class I) 2.04691
PGPEP1 pyroglutamyl-peptidase I 2.04319
CHMP1A charged multivesicular body protein 1A 2.04043
TOX thymocyte selection-associated high mobility group box 2.03583
CES2 carboxylesterase 2 2.01433
MOGS mannosyl-oligosaccharide glucosidase 2.01296
DHDDS dehydrodolichyl diphosphate synthase 2.0069
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 1.99805
ERBB2IP erbb2 interacting protein 1.99749
MFSD10 major facilitator superfamily domain containing 10 1.98318
SREBF2 sterol regulatory element binding transcription factor 2 1.98111
DENND4B DENN/MADD domain containing 4B 1.97046
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.96205
HMGN4 high mobility group nucleosomal binding domain 4 1.95993
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 1.95586
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 1.95316
CACTIN cactin, spliceosome C complex subunit 1.94119
SLC46A3 solute carrier family 46, member 3 1.93849
TCF20 transcription factor 20 (AR1) 1.93261
MIA3 melanoma inhibitory activity family, member 3 1.93173
CYB561D2 cytochrome b561 family, member D2 1.92983
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 1.92393
DCTN5 dynactin 5 (p25) 1.92391
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 1.91378
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 1.912
ARID5B AT rich interactive domain 5B (MRF1-like) 1.91095
MAP3K11 mitogen-activated protein kinase kinase kinase 11 1.91017
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 1.90816
RBBP6 retinoblastoma binding protein 6 1.90321
SGPP1 sphingosine-1-phosphate phosphatase 1 1.89967
TANK TRAF family member-associated NFKB activator 1.8969
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 1.89392
TRAPPC2L trafficking protein particle complex 2-like 1.88647
GOLPH3 golgi phosphoprotein 3 (coat-protein) 1.88642
TMEM222 transmembrane protein 222 1.87903
AAMP angio-associated, migratory cell protein 1.87535
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.87161
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) 1.86964
ISOC1 isochorismatase domain containing 1 1.86529
SP100 SP100 nuclear antigen 1.85532
RAB11A RAB11A, member RAS oncogene family 1.85202
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 1.84669
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 1.84286
CROT carnitine O-octanoyltransferase 1.83893
ZNF80 zinc finger protein 80 1.83875
TRAPPC9 trafficking protein particle complex 9 1.83795
SAMD14 sterile alpha motif domain containing 14 1.83509
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 1.83047
HACD2 3-hydroxyacyl-CoA dehydratase 2 1.82794
ACTA2 actin, alpha 2, smooth muscle, aorta 1.82622
COPS7B COP9 signalosome subunit 7B 1.82527
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 1.82354
ANKRD17 ankyrin repeat domain 17 1.81894
ITSN2 intersectin 2 1.81781
DYNLRB1 dynein, light chain, roadblock-type 1 1.80509
SIRT5 sirtuin 5 1.80426
LRP10 low density lipoprotein receptor-related protein 10 1.80309
LARP7 La ribonucleoprotein domain family, member 7 1.79501
DUSP12 dual specificity phosphatase 12 1.79109
SCYL2 SCY1-like 2 (S. cerevisiae) 1.79006
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 1.79
CSRP1 cysteine and glycine-rich protein 1 1.78723
C2 complement component 2 1.78255
FAM127A family with sequence similarity 127, member A 1.77548
NTAN1 N-terminal asparagine amidase 1.77486
MYD88 myeloid differentiation primary response 88 1.77464
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 1.77453
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa 1.77449
B3GNT1 1.77432
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 1.77257
MR1 major histocompatibility complex, class I-related 1.77226
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 1.77161
NOTCH1 notch 1 1.76662
GOLGA7 golgin A7 1.76463
AQP6 aquaporin 6, kidney specific 1.76434
EML2 echinoderm microtubule associated protein like 2 1.75892
MCM3AP minichromosome maintenance complex component 3 associated protein 1.75877
POTEKP POTE ankyrin domain family, member K, pseudogene 1.75808
TNIP2 TNFAIP3 interacting protein 2 1.75723
AATF apoptosis antagonizing transcription factor 1.75681
TBK1 TANK-binding kinase 1 1.75677
BRD4 bromodomain containing 4 1.75025
RABEP2 rabaptin, RAB GTPase binding effector protein 2 1.74913
MOB1A MOB kinase activator 1A 1.74756
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 1.74548
FAM134A family with sequence similarity 134, member A 1.74142
MCM9 minichromosome maintenance complex component 9 1.73803
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 1.73418
TDRD7 tudor domain containing 7 1.73179
RAB1B RAB1B, member RAS oncogene family 1.72357
NKG7 natural killer cell granule protein 7 1.71705
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 1.71676
NFX1 nuclear transcription factor, X-box binding 1 1.71276
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 1.71203
SDF2 stromal cell-derived factor 2 1.71146
CASC3 cancer susceptibility candidate 3 1.71058
ZNF277 zinc finger protein 277 1.70882
PANK3 pantothenate kinase 3 1.70828
CEP350 centrosomal protein 350kDa 1.70705
UFM1 ubiquitin-fold modifier 1 1.70413
MAP3K7 mitogen-activated protein kinase kinase kinase 7 1.70233
PFDN1 prefoldin subunit 1 1.70004
LASP1 LIM and SH3 protein 1 1.69597
COPS7A COP9 signalosome subunit 7A 1.69548
OPA1 optic atrophy 1 (autosomal dominant) 1.69491
SCAMP1 secretory carrier membrane protein 1 1.69402
CCDC88C coiled-coil domain containing 88C 1.69228
ZC3H11A zinc finger CCCH-type containing 11A 1.68862
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 1.68638
GBP2 guanylate binding protein 2, interferon-inducible 1.68184
TRAM2 translocation associated membrane protein 2 1.68012
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 1.67564
TRIM21 tripartite motif containing 21 1.67524
PGAP3 post-GPI attachment to proteins 3 1.67429
PWP1 PWP1 homolog (S. cerevisiae) 1.6713
DGCR8 DGCR8 microprocessor complex subunit 1.6689
GEMIN7 gem (nuclear organelle) associated protein 7 1.66809
SYT11 synaptotagmin XI 1.66664
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 1.66344
MAML1 mastermind-like 1 (Drosophila) 1.66321
DIABLO diablo, IAP-binding mitochondrial protein 1.65908
HEATR6 HEAT repeat containing 6 1.65803
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 1.6566
EFHD2 EF-hand domain family, member D2 1.65641
RPP38 ribonuclease P/MRP 38kDa subunit 1.65561
GAGE6 G antigen 6 1.65274
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.65266
NOTCH2 notch 2 1.64987
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 1.6491
PTP4A2 protein tyrosine phosphatase type IVA, member 2 1.64726
PLEKHJ1 pleckstrin homology domain containing, family J member 1 1.64317
MAP4 microtubule-associated protein 4 1.64281
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 1.62748
ZNF430 zinc finger protein 430 1.62741
CYTH4 cytohesin 4 1.62472
PRDM1 PR domain containing 1, with ZNF domain 1.62448
VEZF1 vascular endothelial zinc finger 1 1.62375
ZNF839 zinc finger protein 839 1.62245
ZNF195 zinc finger protein 195 1.62201
SLC16A6 solute carrier family 16, member 6 1.62147
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 1.61826
PCGF1 polycomb group ring finger 1 1.61686
RRAGA Ras-related GTP binding A 1.61614
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 1.61084
ATG5 autophagy related 5 1.60578
JAKMIP2 janus kinase and microtubule interacting protein 2 1.6016
MUL1 mitochondrial E3 ubiquitin protein ligase 1 1.60012
CSK c-src tyrosine kinase 1.59956
UBN1 ubinuclein 1 1.59906
FAM160B2 family with sequence similarity 160, member B2 1.5984
BECN1 beclin 1, autophagy related 1.59787
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.59762
ZNF16 zinc finger protein 16 1.59747
GJB3 gap junction protein, beta 3, 31kDa 1.59587
ZNF137P zinc finger protein 137, pseudogene 1.59264
KRT32 keratin 32, type I 1.59224
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 1.59224
MCRS1 microspherule protein 1 1.58946
TMEM163 transmembrane protein 163 1.5802
DMPK dystrophia myotonica-protein kinase 1.57996
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 1.57954
UFD1L ubiquitin fusion degradation 1 like (yeast) 1.57907
RGS3 regulator of G-protein signaling 3 1.57746
WWOX WW domain containing oxidoreductase 1.57733
PTCD1 pentatricopeptide repeat domain 1 1.57346
TBC1D13 TBC1 domain family, member 13 1.57211
POLG polymerase (DNA directed), gamma 1.57158
UBE3A ubiquitin protein ligase E3A 1.56935
IFITM3 interferon induced transmembrane protein 3 1.56896
ACAT2 acetyl-CoA acetyltransferase 2 1.56709
RFESD Rieske (Fe-S) domain containing 1.56507
TRIP4 thyroid hormone receptor interactor 4 1.56374
SRPRB signal recognition particle receptor, B subunit 1.56051
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.56032
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 1.55978
PCF11 PCF11 cleavage and polyadenylation factor subunit 1.55761
ARHGAP25 Rho GTPase activating protein 25 1.55498
GOSR1 golgi SNAP receptor complex member 1 1.55448
TBX21 T-box 21 1.55382
BRD3 bromodomain containing 3 1.55286
ATG13 autophagy related 13 1.54894
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 1.54819
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 1.54425
TMED3 transmembrane emp24 protein transport domain containing 3 1.5418
GRM4 glutamate receptor, metabotropic 4 1.54014
KPNA3 karyopherin alpha 3 (importin alpha 4) 1.54007
ANXA11 annexin A11 1.53972
ZNF468 zinc finger protein 468 1.53873
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 1.53779
PXK PX domain containing serine/threonine kinase 1.5351
BMI1 BMI1 proto-oncogene, polycomb ring finger 1.53498
C2ORF42 chromosome 2 open reading frame 42 1.53262
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase 1.53015
MTMR9 myotubularin related protein 9 1.53007
UBE2W ubiquitin-conjugating enzyme E2W (putative) 1.52978
STOM stomatin 1.52966
TMEM53 transmembrane protein 53 1.52761
PTPRC protein tyrosine phosphatase, receptor type, C 1.52748
LPCAT1 lysophosphatidylcholine acyltransferase 1 1.52662
WSB2 WD repeat and SOCS box containing 2 1.52534
ZNF148 zinc finger protein 148 1.52435
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 1.52004
USP8 ubiquitin specific peptidase 8 1.51919
GAK cyclin G associated kinase 1.51832
GPC3 glypican 3 1.51646
NTSR1 neurotensin receptor 1 (high affinity) 1.51619
RSF1 remodeling and spacing factor 1 1.51511
ELMO2 engulfment and cell motility 2 1.51447
TTC38 tetratricopeptide repeat domain 38 1.51076
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) 1.50901
PRPH peripherin 1.50457
PTPN2 protein tyrosine phosphatase, non-receptor type 2 1.50186
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 1.50181
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 1.49963
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 1.49844
FOXN2 forkhead box N2 1.49738
TMCO1 transmembrane and coiled-coil domains 1 1.4968
FUBP3 far upstream element (FUSE) binding protein 3 1.49452
UGCG UDP-glucose ceramide glucosyltransferase 1.49184
AGFG1 ArfGAP with FG repeats 1 1.49105
PRDM4 PR domain containing 4 1.48708
ZNF438 zinc finger protein 438 1.48677
CFL1 cofilin 1 (non-muscle) 1.48465
CPT1A carnitine palmitoyltransferase 1A (liver) 1.48414
C18ORF8 chromosome 18 open reading frame 8 1.48327
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense 1.48215
ANKMY2 ankyrin repeat and MYND domain containing 2 1.4809
CCL5 chemokine (C-C motif) ligand 5 1.47944
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 1.47815
GSE1 Gse1 coiled-coil protein 1.47722
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 1.47147
RBM23 RNA binding motif protein 23 1.47025
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa 1.47014
IL27RA interleukin 27 receptor, alpha 1.46974
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.46799
BAZ1A bromodomain adjacent to zinc finger domain, 1A 1.4674
SNW1 SNW domain containing 1 1.46712
ZNF778 zinc finger protein 778 1.4655
POLR1B polymerase (RNA) I polypeptide B, 128kDa 1.46503
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 1.46317
MLN motilin 1.46317
ACBD3 acyl-CoA binding domain containing 3 1.46096
FBXL15 F-box and leucine-rich repeat protein 15 1.46079
INPP5F inositol polyphosphate-5-phosphatase F 1.4584
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.45815
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 1.45539
ZNF473 zinc finger protein 473 1.44957
RAB14 RAB14, member RAS oncogene family 1.44887
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 1.4484
NBN nibrin 1.44765
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 1.44696

decreased expression

Symbol Name Standardized Value
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G -3.02689
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -2.92188
RPLP0 ribosomal protein, large, P0 -2.88785
LDHB lactate dehydrogenase B -2.75072
RBMX RNA binding motif protein, X-linked -2.72768
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa -2.70945
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 -2.68538
ERGIC3 ERGIC and golgi 3 -2.66856
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -2.63405
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa -2.62318
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -2.58124
DGKA diacylglycerol kinase, alpha 80kDa -2.53286
RPL36A ribosomal protein L36a -2.52769
NONO non-POU domain containing, octamer-binding -2.51747
LYRM4 LYR motif containing 4 -2.43261
KARS lysyl-tRNA synthetase -2.4122
C19ORF53 chromosome 19 open reading frame 53 -2.37265
TOR1A torsin family 1, member A (torsin A) -2.37039
CLK3 CDC-like kinase 3 -2.33971
SETD3 SET domain containing 3 -2.31867
TRIAP1 TP53 regulated inhibitor of apoptosis 1 -2.31751
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 -2.31596
NOSIP nitric oxide synthase interacting protein -2.28143
GTF3A general transcription factor IIIA -2.27786
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -2.26163
CMC2 C-x(9)-C motif containing 2 -2.25802
ERP29 endoplasmic reticulum protein 29 -2.25554
FBL fibrillarin -2.24302
CALU calumenin -2.24063
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -2.23371
EIF6 eukaryotic translation initiation factor 6 -2.22733
PHB2 prohibitin 2 -2.21891
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent -2.21063
COX7C cytochrome c oxidase subunit VIIc -2.20463
LUC7L LUC7-like (S. cerevisiae) -2.19937
MALT1 MALT1 paracaspase -2.19271
RPS13 ribosomal protein S13 -2.19066
VDAC2 voltage-dependent anion channel 2 -2.19029
CCT8 chaperonin containing TCP1, subunit 8 (theta) -2.17382
SLC38A2 solute carrier family 38, member 2 -2.13316
PANK4 pantothenate kinase 4 -2.11523
FXR1 fragile X mental retardation, autosomal homolog 1 -2.10667
CLINT1 clathrin interactor 1 -2.09356
UXT ubiquitously-expressed, prefoldin-like chaperone -2.09204
RANBP9 RAN binding protein 9 -2.07351
LGALS8 lectin, galactoside-binding, soluble, 8 -2.06966
QARS glutaminyl-tRNA synthetase -2.06954
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.04109
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 -2.03123
LEPROTL1 leptin receptor overlapping transcript-like 1 -2.0276
SERP1 stress-associated endoplasmic reticulum protein 1 -2.01287
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.00463
RPL28 ribosomal protein L28 -1.99319
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -1.97912
PHYH phytanoyl-CoA 2-hydroxylase -1.97493
RPS15 ribosomal protein S15 -1.96986
PABPC1 poly(A) binding protein, cytoplasmic 1 -1.95995
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -1.95693
GNAS GNAS complex locus -1.95328
EIF3E eukaryotic translation initiation factor 3, subunit E -1.94937
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -1.93293
NKRF NFKB repressing factor -1.91832
PLCG1 phospholipase C, gamma 1 -1.91705
HINT1 histidine triad nucleotide binding protein 1 -1.91252
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 -1.89948
IST1 increased sodium tolerance 1 homolog (yeast) -1.89747
EIF4B eukaryotic translation initiation factor 4B -1.87742
NDEL1 nudE neurodevelopment protein 1-like 1 -1.87317
PCYOX1L prenylcysteine oxidase 1 like -1.86793
LGTN ligatin -1.86474
RPLP1 ribosomal protein, large, P1 -1.86316
CCNG1 cyclin G1 -1.85999
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -1.85934
RPL31 ribosomal protein L31 -1.8445
RPL32 ribosomal protein L32 -1.83918
FLT3LG fms-related tyrosine kinase 3 ligand -1.83473
C14ORF93 chromosome 14 open reading frame 93 -1.83026
OSGEP O-sialoglycoprotein endopeptidase -1.82975
RRP1B ribosomal RNA processing 1B -1.82081
CSNK1A1 casein kinase 1, alpha 1 -1.81944
C14ORF2 chromosome 14 open reading frame 2 -1.81766
SFMBT1 Scm-like with four mbt domains 1 -1.81187
COX7CP1 cytochrome c oxidase subunit VIIc pseudogene 1 -1.7996
SERBP1 SERPINE1 mRNA binding protein 1 -1.7973
UBE4B ubiquitination factor E4B -1.78928
RPL22 ribosomal protein L22 -1.7825
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa -1.78232
PRKCA protein kinase C, alpha -1.77577
CCDC109B coiled-coil domain containing 109B -1.77523
TRPC4 transient receptor potential cation channel, subfamily C, member 4 -1.77114
C12ORF10 chromosome 12 open reading frame 10 -1.76937
ZNF142 zinc finger protein 142 -1.76836
H2AFV H2A histone family, member V -1.76768
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -1.76294
UQCRH ubiquinol-cytochrome c reductase hinge protein -1.76226
EIF3H eukaryotic translation initiation factor 3, subunit H -1.76137
EEF2 eukaryotic translation elongation factor 2 -1.75668
RPL19 ribosomal protein L19 -1.75463
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 -1.75425
PJA1 praja ring finger 1, E3 ubiquitin protein ligase -1.7509
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -1.74383
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -1.7427
RPS10 ribosomal protein S10 -1.74148
CASP9 caspase 9, apoptosis-related cysteine peptidase -1.741
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -1.74089
SF3A3 splicing factor 3a, subunit 3, 60kDa -1.73394
MRPS7 mitochondrial ribosomal protein S7 -1.72954
RPS20 ribosomal protein S20 -1.72535
RPSA ribosomal protein SA -1.72208
EEF1B2 eukaryotic translation elongation factor 1 beta 2 -1.72083
CD48 CD48 molecule -1.72015
CRLF3 cytokine receptor-like factor 3 -1.71969
RPS16 ribosomal protein S16 -1.71885
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa -1.71429
TFIP11 tuftelin interacting protein 11 -1.71145
GOLGA8B golgin A8 family, member B -1.70957
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -1.70179
ELMO1 engulfment and cell motility 1 -1.69926
EIF3B eukaryotic translation initiation factor 3, subunit B -1.69524
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 -1.69456
POLR1D polymerase (RNA) I polypeptide D, 16kDa -1.68194
AQP3 aquaporin 3 (Gill blood group) -1.6808
ADSL adenylosuccinate lyase -1.67923
ACTG1 actin gamma 1 -1.67904
RPL29 ribosomal protein L29 -1.67669
FOXJ2 forkhead box J2 -1.67518
CMC4 C-x(9)-C motif containing 4 -1.67491
PQBP1 polyglutamine binding protein 1 -1.6727
TXK TXK tyrosine kinase -1.6673
YIPF5 Yip1 domain family, member 5 -1.66672
HUS1 HUS1 checkpoint homolog (S. pombe) -1.66084
ATG3 autophagy related 3 -1.6582
ZBTB16 zinc finger and BTB domain containing 16 -1.65615
RPL4 ribosomal protein L4 -1.64793
SSR4 signal sequence receptor, delta -1.64508
RPS19 ribosomal protein S19 -1.64149
PTEN phosphatase and tensin homolog -1.63722
HEBP2 heme binding protein 2 -1.6352
CCNI cyclin I -1.62827
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) -1.62532
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) -1.61861
EIF5 eukaryotic translation initiation factor 5 -1.61621
PARL presenilin associated, rhomboid-like -1.61582
RPS18 ribosomal protein S18 -1.61176
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -1.6096
C6ORF48 chromosome 6 open reading frame 48 -1.60854
AHCY adenosylhomocysteinase -1.60557
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -1.60124
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 -1.60103
SND1 staphylococcal nuclease and tudor domain containing 1 -1.59922
EML4 echinoderm microtubule associated protein like 4 -1.59807
RPL10A ribosomal protein L10a -1.59187
CCDC130 coiled-coil domain containing 130 -1.58988
ZMYM4 zinc finger, MYM-type 4 -1.58925
R3HDM1 R3H domain containing 1 -1.58659
ZDHHC3 zinc finger, DHHC-type containing 3 -1.58215
RPS8 ribosomal protein S8 -1.58086
POLR1E polymerase (RNA) I polypeptide E, 53kDa -1.58015
PNP purine nucleoside phosphorylase -1.57141
SNX4 sorting nexin 4 -1.56894
RPL12 ribosomal protein L12 -1.56799
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) -1.56717
RPL13 ribosomal protein L13 -1.56646
EIF3D eukaryotic translation initiation factor 3, subunit D -1.56537
PRDX6 peroxiredoxin 6 -1.5648
C14ORF166 chromosome 14 open reading frame 166 -1.56283
RPS24 ribosomal protein S24 -1.56254
NMD3 NMD3 ribosome export adaptor -1.56173
AP3M2 adaptor-related protein complex 3, mu 2 subunit -1.56086
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) -1.54853
ACAA1 acetyl-CoA acyltransferase 1 -1.54812
CACYBP calcyclin binding protein -1.54607
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) -1.5408
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) -1.54059
POLB polymerase (DNA directed), beta -1.5362
CD248 CD248 molecule, endosialin -1.53443
RPL24 ribosomal protein L24 -1.53166
SPTBN1 spectrin, beta, non-erythrocytic 1 -1.52715
TRIT1 tRNA isopentenyltransferase 1 -1.52589
METAP1 methionyl aminopeptidase 1 -1.5233
MZT2B mitotic spindle organizing protein 2B -1.52168
MAN1C1 mannosidase, alpha, class 1C, member 1 -1.51659
GPX7 glutathione peroxidase 7 -1.51615
EIF3L eukaryotic translation initiation factor 3, subunit L -1.51555
RPL7A ribosomal protein L7a -1.50805
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 -1.50147
RIT1 Ras-like without CAAX 1 -1.50127
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -1.50047
RHOH ras homolog family member H -1.50045
MORC4 MORC family CW-type zinc finger 4 -1.49956
GRHPR glyoxylate reductase/hydroxypyruvate reductase -1.49482
LRRC37A leucine rich repeat containing 37A -1.49382
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -1.49299
DRG1 developmentally regulated GTP binding protein 1 -1.49292
NCKIPSD NCK interacting protein with SH3 domain -1.48667
UXS1 UDP-glucuronate decarboxylase 1 -1.48648
MYDGF myeloid-derived growth factor -1.4861
CCT4 chaperonin containing TCP1, subunit 4 (delta) -1.48601
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 -1.48508
ENY2 enhancer of yellow 2 homolog (Drosophila) -1.48259
KIF5B kinesin family member 5B -1.48168
HSPA8 heat shock 70kDa protein 8 -1.48
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -1.47275
NARS asparaginyl-tRNA synthetase -1.46838
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -1.46563
PDK3 pyruvate dehydrogenase kinase, isozyme 3 -1.46491
RPS7 ribosomal protein S7 -1.46139
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -1.46046
JTB jumping translocation breakpoint -1.46042
SIAH1 siah E3 ubiquitin protein ligase 1 -1.4603
ATXN7L3B ataxin 7-like 3B -1.45577
TWF2 twinfilin actin binding protein 2 -1.45445
RAX retina and anterior neural fold homeobox -1.45367
JAM3 junctional adhesion molecule 3 -1.4515
CLTA clathrin, light chain A -1.45077
RPS3A ribosomal protein S3A -1.45031
SLC44A5 solute carrier family 44, member 5 -1.44984
RPL11 ribosomal protein L11 -1.44535
RPL3 ribosomal protein L3 -1.44476
SNRPE small nuclear ribonucleoprotein polypeptide E -1.43721
RPL27 ribosomal protein L27 -1.43483
BBC3 BCL2 binding component 3 -1.43335
RPS21 ribosomal protein S21 -1.43307
MCAM melanoma cell adhesion molecule -1.4329
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) -1.43063
CCNH cyclin H -1.43051
TRIM28 tripartite motif containing 28 -1.42678
CLNS1A chloride channel, nucleotide-sensitive, 1A -1.42264
FIP1L1 factor interacting with PAPOLA and CPSF1 -1.42038
LPP LIM domain containing preferred translocation partner in lipoma -1.42016
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -1.41952
MAPRE1 microtubule-associated protein, RP/EB family, member 1 -1.41644
AKAP7 A kinase (PRKA) anchor protein 7 -1.41261
ZFAND1 zinc finger, AN1-type domain 1 -1.41256
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 -1.41195
TTC19 tetratricopeptide repeat domain 19 -1.40883
ATF4 activating transcription factor 4 -1.40766
KIAA0391 KIAA0391 -1.40564
PPIA peptidylprolyl isomerase A (cyclophilin A) -1.40545
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -1.40532
RBM19 RNA binding motif protein 19 -1.40438
DCTN4 dynactin 4 (p62) -1.40245
RPS5 ribosomal protein S5 -1.40173
YBX1 Y box binding protein 1 -1.40086
UBE2D3 ubiquitin-conjugating enzyme E2D 3 -1.40017
ADK adenosine kinase -1.39664
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -1.39505
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -1.39493
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -1.39393
RAB33A RAB33A, member RAS oncogene family -1.39321
MTMR1 myotubularin related protein 1 -1.3929
KLHL3 kelch-like family member 3 -1.39066
AIM1 absent in melanoma 1 -1.39021
GSS glutathione synthetase -1.38984
SLC30A5 solute carrier family 30 (zinc transporter), member 5 -1.38941
MAX MYC associated factor X -1.38482
SELT selenoprotein T -1.38385
HIST1H1C histone cluster 1, H1c -1.3825
TRIB2 tribbles pseudokinase 2 -1.38214
TPK1 thiamin pyrophosphokinase 1 -1.38095
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -1.38081
ZNF706 zinc finger protein 706 -1.38061
THPO thrombopoietin -1.37506
SEPT6 septin 6 -1.37467
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 -1.37429
FAM102A family with sequence similarity 102, member A -1.37408
MRPL34 mitochondrial ribosomal protein L34 -1.36683
NPM3 nucleophosmin/nucleoplasmin 3 -1.36173
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -1.36024
AGBL5 ATP/GTP binding protein-like 5 -1.35939
C11ORF95 chromosome 11 open reading frame 95 -1.35912
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -1.35508
PLXDC1 plexin domain containing 1 -1.35445
RPL23A ribosomal protein L23a -1.35341
PGK1 phosphoglycerate kinase 1 -1.35222
LUZP1 leucine zipper protein 1 -1.35208
COPS6 COP9 signalosome subunit 6 -1.35143
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit -1.35018
TRDMT1 tRNA aspartic acid methyltransferase 1 -1.34599
IL4R interleukin 4 receptor -1.34552
SFXN1 sideroflexin 1 -1.34256
ATHL1 ATH1, acid trehalase-like 1 (yeast) -1.34152
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -1.33964
PITRM1 pitrilysin metallopeptidase 1 -1.3369
RPL13A ribosomal protein L13a -1.3346
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -1.3343
GMCL1 germ cell-less, spermatogenesis associated 1 -1.33342
SAP130 Sin3A-associated protein, 130kDa -1.33309
CENPN centromere protein N -1.33219
IVNS1ABP influenza virus NS1A binding protein -1.33102
TAZ tafazzin -1.32922
CRYBA2 crystallin, beta A2 -1.32255
EIF4A1 eukaryotic translation initiation factor 4A1 -1.32204
CCDC64 coiled-coil domain containing 64 -1.32036
CCBL2 cysteine conjugate-beta lyase 2 -1.31962
ABHD5 abhydrolase domain containing 5 -1.31798
CERS6 ceramide synthase 6 -1.31655
CREM cAMP responsive element modulator -1.31582
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) -1.31432
NXT1 nuclear transport factor 2-like export factor 1 -1.3094