LCLC-97TM1 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: carcinoma, large cell (Cell Line Ontology, CLO_0007283)
Similar Terms
Downloads & Tools

Genes

303 genes with high or low expression in LCLC-97TM1 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
XDH xanthine dehydrogenase 3.03267
SPRR2C small proline-rich protein 2C (pseudogene) 2.60923
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.53783
LTA4H leukotriene A4 hydrolase 2.44385
OAT ornithine aminotransferase 2.40582
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 2.35671
PRSS3P2 protease, serine, 3 pseudogene 2 2.34878
PRSS1 protease, serine, 1 (trypsin 1) 2.33345
BMP3 bone morphogenetic protein 3 2.27743
CPD carboxypeptidase D 2.23504
PRSS2 protease, serine, 2 (trypsin 2) 2.21829
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa 2.20565
CCL20 chemokine (C-C motif) ligand 20 2.19766
POLB polymerase (DNA directed), beta 2.18202
ADAM15 ADAM metallopeptidase domain 15 2.12474
ASPH aspartate beta-hydroxylase 2.10874
LYN LYN proto-oncogene, Src family tyrosine kinase 2.06792
LPCAT1 lysophosphatidylcholine acyltransferase 1 2.06677
CNOT8 CCR4-NOT transcription complex, subunit 8 2.04652
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 2.0204
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 1.99736
SRD5A3 steroid 5 alpha-reductase 3 1.96941
KCTD5 potassium channel tetramerization domain containing 5 1.95707
ACAD8 acyl-CoA dehydrogenase family, member 8 1.9308
SFTPB surfactant protein B 1.92161
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.88087
LCN2 lipocalin 2 1.86871
RPL35A ribosomal protein L35a 1.8611
EIF4H eukaryotic translation initiation factor 4H 1.84011
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.79108
ADGRF1 adhesion G protein-coupled receptor F1 1.77589
MAP3K8 mitogen-activated protein kinase kinase kinase 8 1.76651
TMBIM6 transmembrane BAX inhibitor motif containing 6 1.7545
LRRC59 leucine rich repeat containing 59 1.75187
ERO1L ERO1-like (S. cerevisiae) 1.73823
CAB39 calcium binding protein 39 1.72887
NOTCH2 notch 2 1.7242
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 1.71754
NTHL1 nth endonuclease III-like 1 (E. coli) 1.70987
MET MET proto-oncogene, receptor tyrosine kinase 1.70653
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 1.6845
FAM3C family with sequence similarity 3, member C 1.67443
CAPN2 calpain 2, (m/II) large subunit 1.67437
ADGRF5 adhesion G protein-coupled receptor F5 1.67139
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.66714
PGLYRP4 peptidoglycan recognition protein 4 1.64673
FNDC3B fibronectin type III domain containing 3B 1.64482
CLTC clathrin, heavy chain (Hc) 1.64131
PHB prohibitin 1.63787
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 1.63545
ARFIP1 ADP-ribosylation factor interacting protein 1 1.6232
PTRH2 peptidyl-tRNA hydrolase 2 1.61922
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 1.58881
OVOL1 ovo-like zinc finger 1 1.58721
ILF2 interleukin enhancer binding factor 2 1.58365
IFI44 interferon-induced protein 44 1.57612
TMEM165 transmembrane protein 165 1.54866
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 1.53087
PLAU plasminogen activator, urokinase 1.5287
CLDN6 claudin 6 1.52069
CXCL8 chemokine (C-X-C motif) ligand 8 1.51927
PLAT plasminogen activator, tissue 1.51921
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.51827
SPRR2B small proline-rich protein 2B 1.51673
TLK2 tousled-like kinase 2 1.4955
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 1.49458
SAA1 serum amyloid A1 1.4802
SPRR1B small proline-rich protein 1B 1.47622
MRPL3 mitochondrial ribosomal protein L3 1.47011
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.46852
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.4628
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.4598
PON2 paraoxonase 2 1.44938
STEAP4 STEAP family member 4 1.44213
TMED2 transmembrane emp24 domain trafficking protein 2 1.43867
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 1.43392
UBE2D3 ubiquitin-conjugating enzyme E2D 3 1.42676
PON3 paraoxonase 3 1.42391
CTSC cathepsin C 1.42262
LMAN1 lectin, mannose-binding, 1 1.41811

low expression

Symbol Name Standardized Value
JAG1 jagged 1 -3.08589
GUSB glucuronidase, beta -2.88648
FOXO4 forkhead box O4 -2.84137
PODNL1 podocan-like 1 -2.74765
MC3R melanocortin 3 receptor -2.71959
CCDC106 coiled-coil domain containing 106 -2.61292
MKKS McKusick-Kaufman syndrome -2.60001
CLEC4A C-type lectin domain family 4, member A -2.59786
PTPRG protein tyrosine phosphatase, receptor type, G -2.56322
GZMK granzyme K (granzyme 3; tryptase II) -2.54147
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 -2.51123
MTCP1 mature T-cell proliferation 1 -2.50819
SRY sex determining region Y -2.50656
ZNF580 zinc finger protein 580 -2.50564
TFIP11 tuftelin interacting protein 11 -2.48751
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 -2.47205
HIST2H2AA3 histone cluster 2, H2aa3 -2.45059
LZTS1 leucine zipper, putative tumor suppressor 1 -2.41475
GUCY2C guanylate cyclase 2C -2.41026
ALOX12B arachidonate 12-lipoxygenase, 12R type -2.40881
FBXO22 F-box protein 22 -2.4085
MATN2 matrilin 2 -2.38558
HSDL2 hydroxysteroid dehydrogenase like 2 -2.36171
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) -2.2898
SCN3B sodium channel, voltage gated, type III beta subunit -2.22427
CORO7 coronin 7 -2.22408
MEG3 maternally expressed 3 (non-protein coding) -2.19284
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 -2.18301
CPNE1 copine I -2.17886
MAGED2 melanoma antigen family D2 -2.17754
JAK3 Janus kinase 3 -2.16773
IL36A interleukin 36, alpha -2.15836
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 -2.14675
ADCY8 adenylate cyclase 8 (brain) -2.13517
MTA2 metastasis associated 1 family, member 2 -2.12642
PLCE1 phospholipase C, epsilon 1 -2.12369
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -2.11294
MDC1 mediator of DNA-damage checkpoint 1 -2.10754
C2 complement component 2 -2.08358
KCTD7 potassium channel tetramerization domain containing 7 -2.08115
OMD osteomodulin -2.08009
OLFML2B olfactomedin-like 2B -2.04983
IGLL1 immunoglobulin lambda-like polypeptide 1 -2.0407
LRRC3 leucine rich repeat containing 3 -2.03886
FMOD fibromodulin -2.02853
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.02818
STIM1 stromal interaction molecule 1 -2.02486
ARID3B AT rich interactive domain 3B (BRIGHT-like) -2.02356
FBXO2 F-box protein 2 -2.02196
ZNF324 zinc finger protein 324 -2.01521
LOC155060 AI894139 pseudogene -2.01399
CCDC64 coiled-coil domain containing 64 -2.00944
PHKG1 phosphorylase kinase, gamma 1 (muscle) -1.99731
DXO decapping exoribonuclease -1.99087
FEZF2 FEZ family zinc finger 2 -1.9724
SFRP4 secreted frizzled-related protein 4 -1.96547
CD163 CD163 molecule -1.96095
CUTA cutA divalent cation tolerance homolog (E. coli) -1.95663
PSD pleckstrin and Sec7 domain containing -1.94802
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 -1.94772
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene -1.94555
GALR3 galanin receptor 3 -1.94032
KALRN kalirin, RhoGEF kinase -1.93157
BCO1 beta-carotene oxygenase 1 -1.92781
PHF1 PHD finger protein 1 -1.92171
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 -1.91905
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 -1.90935
HIST1H2BJ histone cluster 1, H2bj -1.90564
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 -1.89933
SPTBN4 spectrin, beta, non-erythrocytic 4 -1.88918
GOLGA8A golgin A8 family, member A -1.88603
CRISP2 cysteine-rich secretory protein 2 -1.88433
ICAM5 intercellular adhesion molecule 5, telencephalin -1.87366
FGFR1 fibroblast growth factor receptor 1 -1.87239
KRT84 keratin 84, type II -1.86838
SPINK1 serine peptidase inhibitor, Kazal type 1 -1.86384
LAMA1 laminin, alpha 1 -1.85663
GPATCH1 G patch domain containing 1 -1.84211
MAP1A microtubule-associated protein 1A -1.83401
CCDC130 coiled-coil domain containing 130 -1.82705
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -1.82359
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) -1.82013
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide -1.81582
TLR4 toll-like receptor 4 -1.80963
MTMR10 myotubularin related protein 10 -1.80588
IGFBP7 insulin-like growth factor binding protein 7 -1.80216
BAMBI BMP and activin membrane-bound inhibitor -1.79318
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -1.78645
OCEL1 occludin/ELL domain containing 1 -1.77876
HCRT hypocretin (orexin) neuropeptide precursor -1.76727
PGBD5 piggyBac transposable element derived 5 -1.75887
NECAB2 N-terminal EF-hand calcium binding protein 2 -1.75845
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 -1.74633
EIF3FP2 eukaryotic translation initiation factor 3, subunit F pseudogene 2 -1.74546
PXMP4 peroxisomal membrane protein 4, 24kDa -1.73782
ACTG2 actin, gamma 2, smooth muscle, enteric -1.73319
POPDC2 popeye domain containing 2 -1.73049
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -1.72867
TSPYL2 TSPY-like 2 -1.72855
KLK8 kallikrein-related peptidase 8 -1.72758
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 -1.71636
TEX13A testis expressed 13A -1.71619
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 -1.71153
EFNB3 ephrin-B3 -1.69983
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 -1.68207
AOC3 amine oxidase, copper containing 3 -1.68167
VPS33B vacuolar protein sorting 33 homolog B (yeast) -1.66725
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta -1.66591
TRH thyrotropin-releasing hormone -1.66579
ESRRB estrogen-related receptor beta -1.6634
NPPC natriuretic peptide C -1.66162
TTBK2 tau tubulin kinase 2 -1.6567
IRS4 insulin receptor substrate 4 -1.65605
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 -1.65482
CFDP1 craniofacial development protein 1 -1.65391
PLA2G5 phospholipase A2, group V -1.64829
ELMO2 engulfment and cell motility 2 -1.6459
LGI1 leucine-rich, glioma inactivated 1 -1.63886
MAPRE1 microtubule-associated protein, RP/EB family, member 1 -1.63724
ILK integrin-linked kinase -1.63626
AMH anti-Mullerian hormone -1.63063
TBCB tubulin folding cofactor B -1.62999
IFNA2 interferon, alpha 2 -1.62885
MAGEA11 melanoma antigen family A11 -1.62352
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -1.62286
ZEB1 zinc finger E-box binding homeobox 1 -1.61768
AQP1 aquaporin 1 (Colton blood group) -1.61662
HOXD10 homeobox D10 -1.61611
CCL11 chemokine (C-C motif) ligand 11 -1.61482
PDZK1 PDZ domain containing 1 -1.61268
DGCR14 DiGeorge syndrome critical region gene 14 -1.60393
ACTR5 ARP5 actin-related protein 5 homolog (yeast) -1.60163
RNF114 ring finger protein 114 -1.59368
DIO1 deiodinase, iodothyronine, type I -1.59303
OR7C2 olfactory receptor, family 7, subfamily C, member 2 -1.59163
SCN9A sodium channel, voltage gated, type IX alpha subunit -1.59061
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -1.58851
FAM3A family with sequence similarity 3, member A -1.58601
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 -1.58597
BEST1 bestrophin 1 -1.5857
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -1.58529
ZNRF4 zinc and ring finger 4 -1.58487
RBMX2 RNA binding motif protein, X-linked 2 -1.58433
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) -1.58401
DSC1 desmocollin 1 -1.57737
LIN7A lin-7 homolog A (C. elegans) -1.57364
NMBR neuromedin B receptor -1.57073
SIM2 single-minded family bHLH transcription factor 2 -1.56633
ZNF749 zinc finger protein 749 -1.56511
GPX2 glutathione peroxidase 2 -1.55958
SCAND1 SCAN domain containing 1 -1.55955
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -1.55851
NRL neural retina leucine zipper -1.55847
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 -1.55166
PLVAP plasmalemma vesicle associated protein -1.54756
MBNL3 muscleblind-like splicing regulator 3 -1.54733
ZNF215 zinc finger protein 215 -1.54631
HBA2 hemoglobin, alpha 2 -1.54614
PSG6 pregnancy specific beta-1-glycoprotein 6 -1.54552
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 -1.54536
PRKACA protein kinase, cAMP-dependent, catalytic, alpha -1.53932
USH1C Usher syndrome 1C (autosomal recessive, severe) -1.53672
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F -1.53496
RAB40A RAB40A, member RAS oncogene family -1.53372
FBN1 fibrillin 1 -1.53236
ANKRD55 ankyrin repeat domain 55 -1.5317
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma -1.52687
TESC tescalcin -1.52637
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 -1.51527
CDK5RAP1 CDK5 regulatory subunit associated protein 1 -1.51445
NT5M 5',3'-nucleotidase, mitochondrial -1.50926
CR1 complement component (3b/4b) receptor 1 (Knops blood group) -1.5077
SPP2 secreted phosphoprotein 2, 24kDa -1.50651
MYLK myosin light chain kinase -1.50363
TACC1 transforming, acidic coiled-coil containing protein 1 -1.49676
ZNF337 zinc finger protein 337 -1.49636
ETV2 ets variant 2 -1.49614
ZNF334 zinc finger protein 334 -1.49605
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 -1.49284
ENO3 enolase 3 (beta, muscle) -1.49007
PTH2R parathyroid hormone 2 receptor -1.48867
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B -1.4865
IL13RA2 interleukin 13 receptor, alpha 2 -1.48587
CRYBB3 crystallin, beta B3 -1.48546
FOXC2 forkhead box C2 -1.48199
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 -1.481
PPP1R3D protein phosphatase 1, regulatory subunit 3D -1.48062
KDM4D lysine (K)-specific demethylase 4D -1.48042
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit -1.48004
FSD1 fibronectin type III and SPRY domain containing 1 -1.47937
BNC2 basonuclin 2 -1.47681
RFXAP regulatory factor X-associated protein -1.4741
BCORL1 BCL6 corepressor-like 1 -1.47267
GPR1 G protein-coupled receptor 1 -1.47009
MAPKBP1 mitogen-activated protein kinase binding protein 1 -1.46989
TAS2R3 taste receptor, type 2, member 3 -1.46915
GNMT glycine N-methyltransferase -1.46633
KLHL41 kelch-like family member 41 -1.4633
CNR2 cannabinoid receptor 2 (macrophage) -1.46172
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 -1.45725
KPTN kaptin (actin binding protein) -1.45502
MAP3K10 mitogen-activated protein kinase kinase kinase 10 -1.44951
GFRA1 GDNF family receptor alpha 1 -1.4486
ZSWIM1 zinc finger, SWIM-type containing 1 -1.44774
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene) -1.44697
RAP2A RAP2A, member of RAS oncogene family -1.44347
RANBP3 RAN binding protein 3 -1.43979
KRBOX4 KRAB box domain containing 4 -1.43916
NSFL1C NSFL1 (p97) cofactor (p47) -1.43906
FAM50A family with sequence similarity 50, member A -1.43596
PEX16 peroxisomal biogenesis factor 16 -1.43577
NDRG3 NDRG family member 3 -1.43494
MRPS18C mitochondrial ribosomal protein S18C -1.43465
ARTN artemin -1.43107
OR5I1 olfactory receptor, family 5, subfamily I, member 1 -1.42882
RABAC1 Rab acceptor 1 (prenylated) -1.4277
CYBRD1 cytochrome b reductase 1 -1.42694
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit -1.42563
FOXN3 forkhead box N3 -1.42388
PIGT phosphatidylinositol glycan anchor biosynthesis, class T -1.41936
PTOV1 prostate tumor overexpressed 1 -1.4171
RCVRN recoverin -1.41696
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) -1.41598