LCLC-103H Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: carcinoma, large cell (Cell Line Ontology, CLO_0007282)
Similar Terms
Downloads & Tools


129 genes mutated in the LCLC-103H cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ACKR3 atypical chemokine receptor 3
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16
ADGRG2 adhesion G protein-coupled receptor G2
ALMS1 Alstrom syndrome protein 1
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6
ARHGAP32 Rho GTPase activating protein 32
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARID1B AT rich interactive domain 1B (SWI1-like)
ARSE arylsulfatase E (chondrodysplasia punctata 1)
ASTN1 astrotactin 1
ATF6 activating transcription factor 6
ATF7IP activating transcription factor 7 interacting protein
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATXN1 ataxin 1
BRWD1 bromodomain and WD repeat domain containing 1
C16ORF93 chromosome 16 open reading frame 93
C1ORF35 chromosome 1 open reading frame 35
CABIN1 calcineurin binding protein 1
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CD109 CD109 molecule
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CENPF centromere protein F, 350/400kDa
CORO2A coronin, actin binding protein, 2A
DGKI diacylglycerol kinase, iota
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37
DLG5 discs, large homolog 5 (Drosophila)
DOCK1 dedicator of cytokinesis 1
DOCK10 dedicator of cytokinesis 10
DSP desmoplakin
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ESYT2 extended synaptotagmin-like protein 2
FAM160A1 family with sequence similarity 160, member A1
FBXO30 F-box protein 30
FCHSD1 FCH and double SH3 domains 1
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GLIPR2 GLI pathogenesis-related 2
GTF3C6 general transcription factor IIIC, polypeptide 6, alpha 35kDa
HDAC9 histone deacetylase 9
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HSDL2 hydroxysteroid dehydrogenase like 2
HTT huntingtin
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IQSEC1 IQ motif and Sec7 domain 1
KALRN kalirin, RhoGEF kinase
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0408 KIAA0408
KIAA1217 KIAA1217
KIAA1549L KIAA1549-like
KMT2B lysine (K)-specific methyltransferase 2B
LARS leucyl-tRNA synthetase
LIMCH1 LIM and calponin homology domains 1
LIN7B lin-7 homolog B (C. elegans)
LRP5 low density lipoprotein receptor-related protein 5
LY75 lymphocyte antigen 75
LY75-CD302 LY75-CD302 readthrough
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3
MAN2A1 mannosidase, alpha, class 2A, member 1
MAU2 MAU2 sister chromatid cohesion factor
MCOLN3 mucolipin 3
MRPL39 mitochondrial ribosomal protein L39
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NARF nuclear prelamin A recognition factor
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFIA nuclear factor I/A
NPR1 natriuretic peptide receptor 1
NRXN3 neurexin 3
NUP107 nucleoporin 107kDa
PARD3B par-3 family cell polarity regulator beta
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative)
PCNXL3 pecanex-like 3 (Drosophila)
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PGRMC1 progesterone receptor membrane component 1
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PKP2 plakophilin 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PMEPA1 prostate transmembrane protein, androgen induced 1
PURG purine-rich element binding protein G
RAI1 retinoic acid induced 1
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RCC2 regulator of chromosome condensation 2
RXRA retinoid X receptor, alpha
SART3 squamous cell carcinoma antigen recognized by T cells 3
SCFD2 sec1 family domain containing 2
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SETD2 SET domain containing 2
SHANK1 SH3 and multiple ankyrin repeat domains 1
SHCBP1 SHC SH2-domain binding protein 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC39A11 solute carrier family 39, member 11
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMC6 structural maintenance of chromosomes 6
SQRDL sulfide quinone reductase-like (yeast)
STK36 serine/threonine kinase 36
SUN3 Sad1 and UNC84 domain containing 3
SYNE2 spectrin repeat containing, nuclear envelope 2
SYNJ1 synaptojanin 1
TADA3 transcriptional adaptor 3
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TBC1D31 TBC1 domain family, member 31
TIGD5 tigger transposable element derived 5
TLE4 transducin-like enhancer of split 4
TMEM209 transmembrane protein 209
TMOD3 tropomodulin 3 (ubiquitous)
TNRC18 trinucleotide repeat containing 18
TNS1 tensin 1
TP53 tumor protein p53
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TSC22D2 TSC22 domain family, member 2
TSEN54 TSEN54 tRNA splicing endonuclease subunit
TTC26 tetratricopeptide repeat domain 26
TTK TTK protein kinase
TTN titin
UGT8 UDP glycosyltransferase 8
URGCP upregulator of cell proliferation
USP34 ubiquitin specific peptidase 34
USP35 ubiquitin specific peptidase 35
UVSSA UV-stimulated scaffold protein A
WDR36 WD repeat domain 36
WIBG within bgcn homolog (Drosophila)
WNK2 WNK lysine deficient protein kinase 2
ZFAT zinc finger and AT hook domain containing
ZNF24 zinc finger protein 24
ZNF695 zinc finger protein 695
ZSCAN18 zinc finger and SCAN domain containing 18