LARGE Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description like-glycosyltransferase|This gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. Mutations in this gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9215)
External Link http://www.ncbi.nlm.nih.gov/gene/9215
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Genes

2 interacting proteins for LARGE from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
B3GNT1
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)