Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5591-11A-01R-1541-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Kidney renal clear cell carcinoma_KIRC (The Cancer Genome Atlas)
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Genes

392 genes with high or low expression in Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5591-11A-01R-1541-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A2M alpha-2-macroglobulin
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABI3BP ABI family, member 3 (NESH) binding protein
ABLIM3 actin binding LIM protein family, member 3
ACADL acyl-CoA dehydrogenase, long chain
ACE angiotensin I converting enzyme
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACSL6 acyl-CoA synthetase long-chain family member 6
ACVR1 activin A receptor, type I
ADAM28 ADAM metallopeptidase domain 28
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
ADAMTSL3 ADAMTS-like 3
ADGRG2 adhesion G protein-coupled receptor G2
ADPRH ADP-ribosylarginine hydrolase
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
AFF2 AF4/FMR2 family, member 2
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHCYL2 adenosylhomocysteinase-like 2
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
AMOT angiomotin
ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 readthrough
ANO7 anoctamin 7
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
APC adenomatous polyposis coli
APC2 adenomatosis polyposis coli 2
APOB apolipoprotein B
APOL6 apolipoprotein L, 6
AQP9 aquaporin 9
AR androgen receptor
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARID3C AT rich interactive domain 3C (BRIGHT-like)
ARL10 ADP-ribosylation factor-like 10
ARL15 ADP-ribosylation factor-like 15
ARMCX6 armadillo repeat containing, X-linked 6
ARSE arylsulfatase E (chondrodysplasia punctata 1)
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG9A autophagy related 9A
ATL3 atlastin GTPase 3
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
BAALC brain and acute leukemia, cytoplasmic
BAG4 BCL2-associated athanogene 4
BCKDK branched chain ketoacid dehydrogenase kinase
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCORL1 BCL6 corepressor-like 1
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BPI bactericidal/permeability-increasing protein
BRS3 bombesin-like receptor 3
C8ORF22 chromosome 8 open reading frame 22
C8ORF48 chromosome 8 open reading frame 48
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4
CAPN11 calpain 11
CAST calpastatin
CCDC115 coiled-coil domain containing 115
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CERS6 ceramide synthase 6
CES2 carboxylesterase 2
CHD4 chromodomain helicase DNA binding protein 4
CHD7 chromodomain helicase DNA binding protein 7
CHMP7 charged multivesicular body protein 7
CLASP1 cytoplasmic linker associated protein 1
CLCN4 chloride channel, voltage-sensitive 4
CNOT7 CCR4-NOT transcription complex, subunit 7
CRNKL1 crooked neck pre-mRNA splicing factor 1
CSMD1 CUB and Sushi multiple domains 1
CSNK1A1 casein kinase 1, alpha 1
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYB5R3 cytochrome b5 reductase 3
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCHS1 dachsous cadherin-related 1
DERL1 derlin 1
DGKK diacylglycerol kinase, kappa
DIAPH1 diaphanous-related formin 1
DMD dystrophin
DMXL1 Dmx-like 1
DNPEP aspartyl aminopeptidase
DPYSL2 dihydropyrimidinase-like 2
DTWD2 DTW domain containing 2
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
EFNA2 ephrin-A2
EFR3A EFR3 homolog A (S. cerevisiae)
EIF5A2 eukaryotic translation initiation factor 5A2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPB41L1 erythrocyte membrane protein band 4.1-like 1
ESX1 ESX homeobox 1
ESYT1 extended synaptotagmin-like protein 1
EVX1 even-skipped homeobox 1
FABP12 fatty acid binding protein 12
FADS6 fatty acid desaturase 6
FAM134A family with sequence similarity 134, member A
FAM172A family with sequence similarity 172, member A
FAM196B family with sequence similarity 196, member B
FAM199X family with sequence similarity 199, X-linked
FAM225B family with sequence similarity 225, member B (non-protein coding)
FAM9B family with sequence similarity 9, member B
FBXO21 F-box protein 21
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FER fer (fps/fes related) tyrosine kinase
FGFR1 fibroblast growth factor receptor 1
FGG fibrinogen gamma chain
FHL2 four and a half LIM domains 2
FITM2 fat storage-inducing transmembrane protein 2
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FRZB frizzled-related protein
FZD3 frizzled class receptor 3
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GGCX gamma-glutamyl carboxylase
GGT1 gamma-glutamyltransferase 1
GMCL1 germ cell-less, spermatogenesis associated 1
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPC1 glypican 1
GPKOW G patch domain and KOW motifs
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GPX5 glutathione peroxidase 5
GYS1 glycogen synthase 1 (muscle)
HDAC6 histone deacetylase 6
HELT helt bHLH transcription factor
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HHIP hedgehog interacting protein
HIST1H4H histone cluster 1, H4h
HMCN1 hemicentin 1
HMGB4 high mobility group box 4
HNF4A hepatocyte nuclear factor 4, alpha
HNMT histamine N-methyltransferase
HRASLS2 HRAS-like suppressor 2
HRH2 histamine receptor H2
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
HYALP1 hyaluronoglucosaminidase pseudogene 1
IDO1 indoleamine 2,3-dioxygenase 1
IDS iduronate 2-sulfatase
IFNA2 interferon, alpha 2
IGLON5 IgLON family member 5
IL17RA interleukin 17 receptor A
IL23R interleukin 23 receptor
IL3 interleukin 3
IL33 interleukin 33
IL36A interleukin 36, alpha
IMPG2 interphotoreceptor matrix proteoglycan 2
IQSEC2 IQ motif and Sec7 domain 2
IRS1 insulin receptor substrate 1
ITGA9 integrin, alpha 9
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
ITSN1 intersectin 1 (SH3 domain protein)
KAT6A K(lysine) acetyltransferase 6A
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KDM3B lysine (K)-specific demethylase 3B
KDSR 3-ketodihydrosphingosine reductase
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA0196 KIAA0196
KIAA1191 KIAA1191
KIAA1429 KIAA1429
KIAA1549 KIAA1549
KIAA1755 KIAA1755
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KPNA4 karyopherin alpha 4 (importin alpha 3)
KREMEN1 kringle containing transmembrane protein 1
KRTAP19-8 keratin associated protein 19-8
KRTAP7-1 keratin associated protein 7-1 (gene/pseudogene)
LAMP2 lysosomal-associated membrane protein 2
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial)
LEFTY1 left-right determination factor 1
LHFPL1 lipoma HMGIC fusion partner-like 1
LINC01554 long intergenic non-protein coding RNA 1554
LINC01587 long intergenic non-protein coding RNA 1587
LMO2 LIM domain only 2 (rhombotin-like 1)
LNPEP leucyl/cystinyl aminopeptidase
LOC154449 uncharacterized LOC154449
LOC285593 uncharacterized LOC285593
LOC93432
LRRC3 leucine rich repeat containing 3
LRRC31 leucine rich repeat containing 31
LTC4S leukotriene C4 synthase
LY6E lymphocyte antigen 6 complex, locus E
LY75 lymphocyte antigen 75
M6PR mannose-6-phosphate receptor (cation dependent)
MALL mal, T-cell differentiation protein-like
MAOA monoamine oxidase A
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP7D3 MAP7 domain containing 3
MAPK9 mitogen-activated protein kinase 9
MATN3 matrilin 3
MBNL3 muscleblind-like splicing regulator 3
MED12 mediator complex subunit 12
MED14 mediator complex subunit 14
MEFV Mediterranean fever
MFSD9 major facilitator superfamily domain containing 9
MID2 midline 2
MIEF1 mitochondrial elongation factor 1
MKL2 MKL/myocardin-like 2
MLEC malectin
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MMRN1 multimerin 1
MORF4L2 mortality factor 4 like 2
MSN moesin
MSRB1 methionine sulfoxide reductase B1
MTDH metadherin
MTFR1 mitochondrial fission regulator 1
MTM1 myotubularin 1
MTTP microsomal triglyceride transfer protein
MYH14 myosin, heavy chain 14, non-muscle
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NCKAP1 NCK-associated protein 1
NCMAP noncompact myelin associated protein
NCOA2 nuclear receptor coactivator 2
NCR1 natural cytotoxicity triggering receptor 1
NCR3 natural cytotoxicity triggering receptor 3
NEFL neurofilament, light polypeptide
NEGR1 neuronal growth regulator 1
NIPAL3 NIPA-like domain containing 3
NOMO3 NODAL modulator 3
NPR1 natriuretic peptide receptor 1
NPVF neuropeptide VF precursor
NSDHL NAD(P) dependent steroid dehydrogenase-like
NSG1 neuron specific gene family member 1
NTNG2 netrin G2
NUP50 nucleoporin 50kDa
OIT3 oncoprotein induced transcript 3
OR1S2 olfactory receptor, family 1, subfamily S, member 2
OR2M4 olfactory receptor, family 2, subfamily M, member 4
OR4A16 olfactory receptor, family 4, subfamily A, member 16
OR4A5 olfactory receptor, family 4, subfamily A, member 5
OR6F1 olfactory receptor, family 6, subfamily F, member 1
OR8J1 olfactory receptor, family 8, subfamily J, member 1
OVCH2 ovochymase 2 (gene/pseudogene)
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAM peptidylglycine alpha-amidating monooxygenase
PARP4 poly (ADP-ribose) polymerase family, member 4
PCDHA2 protocadherin alpha 2
PCDHA3 protocadherin alpha 3
PCDHA5 protocadherin alpha 5
PCDHB11 protocadherin beta 11
PCDHB12 protocadherin beta 12
PCDHB7 protocadherin beta 7
PCDHGA9 protocadherin gamma subfamily A, 9
PCDHGB5 protocadherin gamma subfamily B, 5
PCYOX1 prenylcysteine oxidase 1
PDCL3 phosducin-like 3
PDE10A phosphodiesterase 10A
PDE1A phosphodiesterase 1A, calmodulin-dependent
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PECR peroxisomal trans-2-enoyl-CoA reductase
PEMT phosphatidylethanolamine N-methyltransferase
PER4 period circadian clock 3 pseudogene
PEX26 peroxisomal biogenesis factor 26
PGK1 phosphoglycerate kinase 1
PHF20 PHD finger protein 20
PHKA2 phosphorylase kinase, alpha 2 (liver)
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PLA2G12B phospholipase A2, group XIIB
PLEC plectin
PLEKHM3 pleckstrin homology domain containing, family M, member 3
PNMA2 paraneoplastic Ma antigen 2
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POMK protein-O-mannose kinase
POTEC POTE ankyrin domain family, member C
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRDM14 PR domain containing 14
PRDM8 PR domain containing 8
PRICKLE3 prickle homolog 3 (Drosophila)
PROS1 protein S (alpha)
PROSC proline synthetase co-transcribed homolog (bacterial)
PRRC1 proline-rich coiled-coil 1
PSD4 pleckstrin and Sec7 domain containing 4
PTTG1IP pituitary tumor-transforming 1 interacting protein
RAB22A RAB22A, member RAS oncogene family
RAB2A RAB2A, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RAB43 RAB43, member RAS oncogene family
RBBP9 retinoblastoma binding protein 9
RBP7 retinol binding protein 7, cellular
RCAN3 RCAN family member 3
RDH13 retinol dehydrogenase 13 (all-trans/9-cis)
REPS2 RALBP1 associated Eps domain containing 2
RERG RAS-like, estrogen-regulated, growth inhibitor
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RHBDD1 rhomboid domain containing 1
RNASE11 ribonuclease, RNase A family, 11 (non-active)
RNF14 ring finger protein 14
RNLS renalase, FAD-dependent amine oxidase
RXFP1 relaxin/insulin-like family peptide receptor 1
SAP130 Sin3A-associated protein, 130kDa
SCN9A sodium channel, voltage gated, type IX alpha subunit
SDC1 syndecan 1
SEC14L5 SEC14-like 5 (S. cerevisiae)
SERINC3 serine incorporator 3
SGPP2 sphingosine-1-phosphate phosphatase 2
SH2B2 SH2B adaptor protein 2
SH2D7 SH2 domain containing 7
SHE Src homology 2 domain containing E
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC16A14 solute carrier family 16, member 14
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC22A17 solute carrier family 22, member 17
SLC25A18 solute carrier family 25 (glutamate carrier), member 18
SLC25A43 solute carrier family 25, member 43
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC38A1 solute carrier family 38, member 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC5A9 solute carrier family 5 (sodium/sugar cotransporter), member 9
SLC6A10P solute carrier family 6 (neurotransmitter transporter), member 10, pseudogene
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNTG2 syntrophin, gamma 2
SOGA1 suppressor of glucose, autophagy associated 1
SP8 Sp8 transcription factor
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPRR2G small proline-rich protein 2G
SRY sex determining region Y
SSC5D scavenger receptor cysteine rich family, 5 domains
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STAU1 staufen double-stranded RNA binding protein 1
STK39 serine threonine kinase 39
STON1 stonin 1
STON1-GTF2A1L STON1-GTF2A1L readthrough
SUMO3 small ubiquitin-like modifier 3
SYNPO synaptopodin
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TAOK3 TAO kinase 3
TAS2R60 taste receptor, type 2, member 60
TBC1D25 TBC1 domain family, member 25
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TBL1X transducin (beta)-like 1X-linked
TBX10 T-box 10
TENM4 teneurin transmembrane protein 4
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TGM2 transglutaminase 2
TIAM1 T-cell lymphoma invasion and metastasis 1
TM9SF4 transmembrane 9 superfamily protein member 4
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMEM127 transmembrane protein 127
TMEM130 transmembrane protein 130
TMEM232 transmembrane protein 232
TMEM243 transmembrane protein 243, mitochondrial
TMEM63A transmembrane protein 63A
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TP53INP2 tumor protein p53 inducible nuclear protein 2
TPTEP1 transmembrane phosphatase with tensin homology pseudogene 1
TREX2 three prime repair exonuclease 2
TRIM35 tripartite motif containing 35
TRIM36 tripartite motif containing 36
TRIP12 thyroid hormone receptor interactor 12
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRRAP transformation/transcription domain-associated protein
TSHZ2 teashirt zinc finger homeobox 2
TSPAN6 tetraspanin 6
TUBA3D tubulin, alpha 3d
TUBA3E tubulin, alpha 3e
UBE2F ubiquitin-conjugating enzyme E2F (putative)
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
USP51 ubiquitin specific peptidase 51
USP9X ubiquitin specific peptidase 9, X-linked
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VWC2 von Willebrand factor C domain containing 2
VWF von Willebrand factor
WBP2NL WBP2 N-terminal like
WDR44 WD repeat domain 44
WDR55 WD repeat domain 55
YIPF6 Yip1 domain family, member 6
ZAN zonadhesin (gene/pseudogene)
ZMAT4 zinc finger, matrin-type 4
ZNF521 zinc finger protein 521
ZNFX1 zinc finger, NFX1-type containing 1

low expression

Symbol Name
DET1 de-etiolated homolog 1 (Arabidopsis)
FAM21C family with sequence similarity 21, member C
RNF214 ring finger protein 214
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TSEN2 TSEN2 tRNA splicing endonuclease subunit
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)