Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5591-01A-01R-1541-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Kidney renal clear cell carcinoma_KIRC (The Cancer Genome Atlas)
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Genes

369 genes with high or low expression in Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5591-01A-01R-1541-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAA1 aortic aneurysm, familial abdominal 1
AADACL4 arylacetamide deacetylase-like 4
AAK1 AP2 associated kinase 1
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABHD17B abhydrolase domain containing 17B
ABLIM1 actin binding LIM protein 1
ACAD10 acyl-CoA dehydrogenase family, member 10
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTN4 actinin, alpha 4
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAM21 ADAM metallopeptidase domain 21
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16
ADAMTSL2 ADAMTS-like 2
ADGRG1 adhesion G protein-coupled receptor G1
AGBL4 ATP/GTP binding protein-like 4
AKAP12 A kinase (PRKA) anchor protein 12
AMOTL1 angiomotin like 1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANKRD34B ankyrin repeat domain 34B
ANKRD52 ankyrin repeat domain 52
ANXA11 annexin A11
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
AR androgen receptor
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
ATG2A autophagy related 2A
ATXN1L ataxin 1-like
AXIN2 axin 2
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAG5 BCL2-associated athanogene 5
BBX bobby sox homolog (Drosophila)
BCL9 B-cell CLL/lymphoma 9
BEND3 BEN domain containing 3
BEND7 BEN domain containing 7
BICC1 BicC family RNA binding protein 1
BIK BCL2-interacting killer (apoptosis-inducing)
BMF Bcl2 modifying factor
BNC2 basonuclin 2
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1
BRD3 bromodomain containing 3
BTBD7 BTB (POZ) domain containing 7
C1ORF106 chromosome 1 open reading frame 106
C2ORF71 chromosome 2 open reading frame 71
C4ORF19 chromosome 4 open reading frame 19
C5ORF52 chromosome 5 open reading frame 52
C7 complement component 7
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACUL1 CDK2-associated, cullin domain 1
CADM4 cell adhesion molecule 4
CAPN6 calpain 6
CASP6 caspase 6, apoptosis-related cysteine peptidase
CBX6 chromobox homolog 6
CCDC181 coiled-coil domain containing 181
CD2AP CD2-associated protein
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CFAP57 cilia and flagella associated protein 57
CHODL chondrolectin
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLSTN2 calsyntenin 2
CLUH clustered mitochondria (cluA/CLU1) homolog
CNTN1 contactin 1
COL18A1 collagen, type XVIII, alpha 1
COL4A4 collagen, type IV, alpha 4
CPM carboxypeptidase M
CSNK1G1 casein kinase 1, gamma 1
CTTNBP2NL CTTNBP2 N-terminal like
CTXN1 cortexin 1
CUEDC1 CUE domain containing 1
CYP4Z2P cytochrome P450, family 4, subfamily Z, polypeptide 2, pseudogene
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1
DAAM1 dishevelled associated activator of morphogenesis 1
DACH1 dachshund family transcription factor 1
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DBN1 drebrin 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCAF7 DDB1 and CUL4 associated factor 7
DCDC2 doublecortin domain containing 2
DEFB109P1B defensin, beta 109, pseudogene 1B
DEPTOR DEP domain containing MTOR-interacting protein
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DICER1 dicer 1, ribonuclease type III
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DIRC2 disrupted in renal carcinoma 2
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DMRTC1 DMRT-like family C1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DPP3 dipeptidyl-peptidase 3
DSP desmoplakin
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
EDAR ectodysplasin A receptor
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ENAH enabled homolog (Drosophila)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ESYT1 extended synaptotagmin-like protein 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM161B family with sequence similarity 161, member B
FAM199X family with sequence similarity 199, X-linked
FAM83G family with sequence similarity 83, member G
FAM98A family with sequence similarity 98, member A
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FAT1 FAT atypical cadherin 1
FBLN5 fibulin 5
FBXL18 F-box and leucine-rich repeat protein 18
FERMT1 fermitin family member 1
FHOD3 formin homology 2 domain containing 3
FLRT3 fibronectin leucine rich transmembrane protein 3
FMO3 flavin containing monooxygenase 3
FNDC1 fibronectin type III domain containing 1
FRK fyn-related Src family tyrosine kinase
FRMD5 FERM domain containing 5
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
FZD3 frizzled class receptor 3
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GATSL2 GATS protein-like 2
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GDF5 growth differentiation factor 5
GDF7 growth differentiation factor 7
GLB1 galactosidase, beta 1
GLDC glycine dehydrogenase (decarboxylating)
GLIS3 GLIS family zinc finger 3
GMDS GDP-mannose 4,6-dehydratase
GMFB glia maturation factor, beta
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GPC4 glypican 4
GPR156 G protein-coupled receptor 156
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1
HOPX HOP homeobox
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HTT huntingtin
HUNK hormonally up-regulated Neu-associated kinase
IDE insulin-degrading enzyme
IGSF3 immunoglobulin superfamily, member 3
IL17RD interleukin 17 receptor D
ILDR2 immunoglobulin-like domain containing receptor 2
IPO4 importin 4
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB6 integrin, beta 6
ITGB8 integrin, beta 8
JMY junction mediating and regulatory protein, p53 cofactor
JUP junction plakoglobin
KAAG1 kidney associated antigen 1
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KCTD1 potassium channel tetramerization domain containing 1
KDM1B lysine (K)-specific demethylase 1B
KIAA0100 KIAA0100
KIAA0754 KIAA0754
KIAA1161 KIAA1161
KIAA1549 KIAA1549
KIAA1598
KIF1B kinesin family member 1B
KIF1C kinesin family member 1C
KIF26B kinesin family member 26B
KLHL13 kelch-like family member 13
KLK5 kallikrein-related peptidase 5
KLK6 kallikrein-related peptidase 6
KLK7 kallikrein-related peptidase 7
KRTAP5-2 keratin associated protein 5-2
LAD1 ladinin 1
LAMA2 laminin, alpha 2
LAMP1 lysosomal-associated membrane protein 1
LARGE like-glycosyltransferase
LBR lamin B receptor
LDOC1L leucine zipper, down-regulated in cancer 1-like
LEPROT leptin receptor overlapping transcript
LHX1 LIM homeobox 1
LINGO2 leucine rich repeat and Ig domain containing 2
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LOC100129550 uncharacterized LOC100129550
LPP LIM domain containing preferred translocation partner in lipoma
LRP10 low density lipoprotein receptor-related protein 10
LRRC55 leucine rich repeat containing 55
LRRC8B leucine rich repeat containing 8 family, member B
LRRN2 leucine rich repeat neuronal 2
LRRN4 leucine rich repeat neuronal 4
LTF lactotransferrin
LYPLA2P1 lysophospholipase II pseudogene 1
MACF1 microtubule-actin crosslinking factor 1
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAP4 microtubule-associated protein 4
MAP9 microtubule-associated protein 9
MATN3 matrilin 3
MEX3A mex-3 RNA binding family member A
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MISP mitotic spindle positioning
MLXIP MLX interacting protein
MSH3 mutS homolog 3
MT4 metallothionein 4
MTMR12 myotubularin related protein 12
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYO5B myosin VB
MYO6 myosin VI
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NBEAL1 neurobeachin-like 1
NCMAP noncompact myelin associated protein
NEO1 neogenin 1
NF2 neurofibromin 2 (merlin)
NFASC neurofascin
NHSL1 NHS-like 1
NKD1 naked cuticle homolog 1 (Drosophila)
NLGN4Y neuroligin 4, Y-linked
NLN neurolysin (metallopeptidase M3 family)
NMT2 N-myristoyltransferase 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
NSG1 neuron specific gene family member 1
NT5C2 5'-nucleotidase, cytosolic II
NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motif 10
OLFM4 olfactomedin 4
OR10A3 olfactory receptor, family 10, subfamily A, member 3
OR2T34 olfactory receptor, family 2, subfamily T, member 34
PABPC5 poly(A) binding protein, cytoplasmic 5
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARD3 par-3 family cell polarity regulator
PARP4 poly (ADP-ribose) polymerase family, member 4
PAWR PRKC, apoptosis, WT1, regulator
PBRM1 polybromo 1
PCLO piccolo presynaptic cytomatrix protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDLIM5 PDZ and LIM domain 5
PEX26 peroxisomal biogenesis factor 26
PIGR polymeric immunoglobulin receptor
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCD1 phospholipase C, delta 1
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3
PLS1 plastin 1
PLXNB1 plexin B1
PNPLA6 patatin-like phospholipase domain containing 6
POLR1A polymerase (RNA) I polypeptide A, 194kDa
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRICKLE1 prickle homolog 1 (Drosophila)
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PROM1 prominin 1
PRPH2 peripherin 2 (retinal degeneration, slow)
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PRTG protogenin
PRY2 PTPN13-like, Y-linked 2
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PTPRD protein tyrosine phosphatase, receptor type, D
PUM1 pumilio RNA-binding family member 1
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RASD1 RAS, dexamethasone-induced 1
REC8 REC8 meiotic recombination protein
RHPN2 rhophilin, Rho GTPase binding protein 2
RIPPLY1 ripply transcriptional repressor 1
RNF183 ring finger protein 183
RNF213 ring finger protein 213
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RSPH3 radial spoke 3 homolog (Chlamydomonas)
SAMD12 sterile alpha motif domain containing 12
SAMD5 sterile alpha motif domain containing 5
SBK1 SH3 domain binding kinase 1
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEMG1 semenogelin I
SERPINA13P serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 13, pseudogene
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SESN2 sestrin 2
SFRP1 secreted frizzled-related protein 1
SH3D19 SH3 domain containing 19
SHROOM2 shroom family member 2
SHROOM3 shroom family member 3
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC30A2 solute carrier family 30 (zinc transporter), member 2
SLC35F5 solute carrier family 35, member F5
SLC38A9 solute carrier family 38, member 9
SLC41A3 solute carrier family 41, member 3
SLC44A4 solute carrier family 44, member 4
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SMAD1 SMAD family member 1
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNORA14A small nucleolar RNA, H/ACA box 14A
SNORA25 small nucleolar RNA, H/ACA box 25
SNX30 sorting nexin family member 30
SOX4 SRY (sex determining region Y)-box 4
SPNS2 spinster homolog 2 (Drosophila)
SPP1 secreted phosphoprotein 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYN2 synapsin II
SYT16 synaptotagmin XVI
TAC1 tachykinin, precursor 1
TAOK1 TAO kinase 1
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TBC1D19 TBC1 domain family, member 19
TBCK TBC1 domain containing kinase
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TJP1 tight junction protein 1
TJP2 tight junction protein 2
TLE4 transducin-like enhancer of split 4
TM9SF2 transmembrane 9 superfamily member 2
TMCO3 transmembrane and coiled-coil domains 3
TMEM217 transmembrane protein 217
TMOD3 tropomodulin 3 (ubiquitous)
TNC tenascin C
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNIK TRAF2 and NCK interacting kinase
TNMD tenomodulin
TNNI1 troponin I type 1 (skeletal, slow)
TNNT2 troponin T type 2 (cardiac)
TP53BP2 tumor protein p53 binding protein 2
TRIM44 tripartite motif containing 44
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPAN1 tetraspanin 1
TSPAN3 tetraspanin 3
TSPAN6 tetraspanin 6
TTC28 tetratricopeptide repeat domain 28
TTC29 tetratricopeptide repeat domain 29
TTC9 tetratricopeptide repeat domain 9
TTTY4C testis-specific transcript, Y-linked 4C (non-protein coding)
TTTY6B testis-specific transcript, Y-linked 6B (non-protein coding)
UGCG UDP-glucose ceramide glucosyltransferase
ULBP3 UL16 binding protein 3
UNC5CL unc-5 homolog C (C. elegans)-like
USP22 ubiquitin specific peptidase 22
USP6NL USP6 N-terminal like
VCL vinculin
VCP valosin containing protein
VTCN1 V-set domain containing T cell activation inhibitor 1
VWA2 von Willebrand factor A domain containing 2
VWA5A von Willebrand factor A domain containing 5A
WFDC2 WAP four-disulfide core domain 2
WNT7A wingless-type MMTV integration site family, member 7A
WWC1 WW and C2 domain containing 1
XPR1 xenotropic and polytropic retrovirus receptor 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZBTB20 zinc finger and BTB domain containing 20
ZFP92 ZFP92 zinc finger protein
ZNF250 zinc finger protein 250
ZNF503 zinc finger protein 503
ZNF827 zinc finger protein 827
ZSWIM4 zinc finger, SWIM-type containing 4

low expression

Symbol Name
EXOSC9 exosome component 9
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa