Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5680-01A-11R-1541-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Kidney renal clear cell carcinoma_KIRC (The Cancer Genome Atlas)
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Genes

344 genes with high or low expression in Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5680-01A-11R-1541-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AARS2 alanyl-tRNA synthetase 2, mitochondrial
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABHD6 abhydrolase domain containing 6
ACO2 aconitase 2, mitochondrial
ACOT11 acyl-CoA thioesterase 11
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADCY5 adenylate cyclase 5
ADGRG6 adhesion G protein-coupled receptor G6
ADM2 adrenomedullin 2
AFG3L2 AFG3-like AAA ATPase 2
AGBL5 ATP/GTP binding protein-like 5
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
AKAP1 A kinase (PRKA) anchor protein 1
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
AKR7L aldo-keto reductase family 7-like (gene/pseudogene)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALPK3 alpha-kinase 3
AMT aminomethyltransferase
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD29 ankyrin repeat domain 29
ANKRD6 ankyrin repeat domain 6
ANO7 anoctamin 7
AP3D1 adaptor-related protein complex 3, delta 1 subunit
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARX aristaless related homeobox
AS3MT arsenite methyltransferase
ASB13 ankyrin repeat and SOCS box containing 13
ATG4D autophagy related 4D, cysteine peptidase
ATG9A autophagy related 9A
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BAG6 BCL2-associated athanogene 6
BAHD1 bromo adjacent homology domain containing 1
BBS1 Bardet-Biedl syndrome 1
BOK BCL2-related ovarian killer
BSDC1 BSD domain containing 1
BTBD9 BTB (POZ) domain containing 9
C10ORF2 chromosome 10 open reading frame 2
C12ORF49 chromosome 12 open reading frame 49
C1ORF105 chromosome 1 open reading frame 105
C21ORF62 chromosome 21 open reading frame 62
CABIN1 calcineurin binding protein 1
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
CAMTA1 calmodulin binding transcription activator 1
CAPN3 calpain 3, (p94)
CD99L2 CD99 molecule-like 2
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDON cell adhesion associated, oncogene regulated
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CERS1 ceramide synthase 1
CHDH choline dehydrogenase
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CHRND cholinergic receptor, nicotinic, delta (muscle)
CISD1 CDGSH iron sulfur domain 1
CIT citron rho-interacting serine/threonine kinase
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLCN3 chloride channel, voltage-sensitive 3
CLSTN1 calsyntenin 1
CLSTN3 calsyntenin 3
CLUH clustered mitochondria (cluA/CLU1) homolog
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COQ9 coenzyme Q9
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRTC3 CREB regulated transcription coactivator 3
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CTXN3 cortexin 3
CUL7 cullin 7
CX3CL1 chemokine (C-X3-C motif) ligand 1
DGCR2 DiGeorge syndrome critical region gene 2
DHRS13 dehydrogenase/reductase (SDR family) member 13
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30
ECH1 enoyl CoA hydratase 1, peroxisomal
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ENPEP glutamyl aminopeptidase (aminopeptidase A)
F10 coagulation factor X
FABP3 fatty acid binding protein 3, muscle and heart
FAM118B family with sequence similarity 118, member B
FAM134A family with sequence similarity 134, member A
FAM159A family with sequence similarity 159, member A
FAM53A family with sequence similarity 53, member A
FAM53B family with sequence similarity 53, member B
FAM86DP family with sequence similarity 86, member D, pseudogene
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FAT1 FAT atypical cadherin 1
FBLN7 fibulin 7
FBXL5 F-box and leucine-rich repeat protein 5
FBXW4 F-box and WD repeat domain containing 4
FGF16 fibroblast growth factor 16
FMO1 flavin containing monooxygenase 1
FUK fucokinase
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FXR2 fragile X mental retardation, autosomal homolog 2
GALNS galactosamine (N-acetyl)-6-sulfatase
GALNT16 polypeptide N-acetylgalactosaminyltransferase 16
GAREM GRB2 associated, regulator of MAPK1
GBA3 glucosidase, beta, acid 3 (gene/pseudogene)
GLIS2 GLIS family zinc finger 2
GNRH2 gonadotropin-releasing hormone 2
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPI glucose-6-phosphate isomerase
GPR75 G protein-coupled receptor 75
GPR89B G protein-coupled receptor 89B
GRK4 G protein-coupled receptor kinase 4
GRTP1 growth hormone regulated TBC protein 1
GSK3A glycogen synthase kinase 3 alpha
GSTT1 glutathione S-transferase theta 1
H2BFWT H2B histone family, member W, testis-specific
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HHLA2 HERV-H LTR-associating 2
HIRA histone cell cycle regulator
HKDC1 hexokinase domain containing 1
HMGB3 high mobility group box 3
HOMER3 homer scaffolding protein 3
HPCA hippocalcin
IFFO2 intermediate filament family orphan 2
IL17RB interleukin 17 receptor B
IL34 interleukin 34
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
IPO13 importin 13
IQUB IQ motif and ubiquitin domain containing
IRX5 iroquois homeobox 5
ITFG3 integrin alpha FG-GAP repeat containing 3
JAK1 Janus kinase 1
KANSL1 KAT8 regulatory NSL complex subunit 1
KATNAL2 katanin p60 subunit A-like 2
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDM4A lysine (K)-specific demethylase 4A
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA0556 KIAA0556
KIAA1522 KIAA1522
KIAA1614 KIAA1614
KIF1C kinesin family member 1C
KIF9 kinesin family member 9
KLC2 kinesin light chain 2
KRT77 keratin 77, type II
KY kyphoscoliosis peptidase
LHCGR luteinizing hormone/choriogonadotropin receptor
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LHX4 LIM homeobox 4
LIPF lipase, gastric
LIPJ lipase, family member J
LONP1 lon peptidase 1, mitochondrial
LPCAT3 lysophosphatidylcholine acyltransferase 3
LRRC1 leucine rich repeat containing 1
LRRC46 leucine rich repeat containing 46
LRRC73 leucine rich repeat containing 73
LRRK2 leucine-rich repeat kinase 2
MAPK12 mitogen-activated protein kinase 12
MECR mitochondrial trans-2-enoyl-CoA reductase
MEGF6 multiple EGF-like-domains 6
MEGF8 multiple EGF-like-domains 8
MFN2 mitofusin 2
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MID1 midline 1
MITF microphthalmia-associated transcription factor
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MNX1 motor neuron and pancreas homeobox 1
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRGPRE MAS-related GPR, member E
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYO1C myosin IC
MYO1E myosin IE
NACAD NAC alpha domain containing
NEFL neurofilament, light polypeptide
NFIA nuclear factor I/A
NHSL1 NHS-like 1
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NLRP12 NLR family, pyrin domain containing 12
NMNAT1 nicotinamide nucleotide adenylyltransferase 1
NPB neuropeptide B
NPPC natriuretic peptide C
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NRN1 neuritin 1
NRTN neurturin
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19
NXPH4 neurexophilin 4
OAF OAF homolog (Drosophila)
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OGDHL oxoglutarate dehydrogenase-like
OLIG1 oligodendrocyte transcription factor 1
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OR2T29 olfactory receptor, family 2, subfamily T, member 29
PAIP2B poly(A) binding protein interacting protein 2B
PARD3 par-3 family cell polarity regulator
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative)
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHGA9 protocadherin gamma subfamily A, 9
PDE4D phosphodiesterase 4D, cAMP-specific
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDGFC platelet derived growth factor C
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase
PDZK1P1 PDZ domain containing 1 pseudogene 1
PEX10 peroxisomal biogenesis factor 10
PGAM1 phosphoglycerate mutase 1 (brain)
PGAM4 phosphoglycerate mutase family member 4
PGBD5 piggyBac transposable element derived 5
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
PGM1 phosphoglucomutase 1
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like
PITX1 paired-like homeodomain 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHA7 pleckstrin homology domain containing, family A member 7
PLIN4 perilipin 4
PLXDC2 plexin domain containing 2
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
POU3F3 POU class 3 homeobox 3
PPIF peptidylprolyl isomerase F
PRELID2 PRELI domain containing 2
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRR32 proline rich 32
PTCHD2 patched domain containing 2
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PTPRF protein tyrosine phosphatase, receptor type, F
PTPRS protein tyrosine phosphatase, receptor type, S
PXMP2 peroxisomal membrane protein 2, 22kDa
RAB19 RAB19, member RAS oncogene family
RAB3IP RAB3A interacting protein
RAB6B RAB6B, member RAS oncogene family
RASGEF1A RasGEF domain family, member 1A
RBM38 RNA binding motif protein 38
RBP5 retinol binding protein 5, cellular
RELL1 RELT-like 1
RERE arginine-glutamic acid dipeptide (RE) repeats
RFT1 RFT1 homolog (S. cerevisiae)
RHPN2 rhophilin, Rho GTPase binding protein 2
RNF121 ring finger protein 121
RNF4 ring finger protein 4
RPS10P7 ribosomal protein S10 pseudogene 7
RSG1 REM2 and RAB-like small GTPase 1
SCAP SREBF chaperone
SEC14L3 SEC14-like 3 (S. cerevisiae)
SEC24C SEC24 family member C
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SFMBT1 Scm-like with four mbt domains 1
SGPL1 sphingosine-1-phosphate lyase 1
SHISA9 shisa family member 9
SIK2 salt-inducible kinase 2
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1
SLC16A13 solute carrier family 16, member 13
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC25A30 solute carrier family 25, member 30
SLC25A34 solute carrier family 25, member 34
SLC26A9 solute carrier family 26 (anion exchanger), member 9
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1
SLC30A2 solute carrier family 30 (zinc transporter), member 2
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
SLC35F6 solute carrier family 35, member F6
SLC39A13 solute carrier family 39 (zinc transporter), member 13
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC41A1 solute carrier family 41 (magnesium transporter), member 1
SLC41A3 solute carrier family 41, member 3
SLC46A1 solute carrier family 46 (folate transporter), member 1
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMO smoothened, frizzled class receptor
SMTNL2 smoothelin-like 2
SNAP47 synaptosomal-associated protein, 47kDa
SNX29 sorting nexin 29
SORBS2 sorbin and SH3 domain containing 2
SOX12 SRY (sex determining region Y)-box 12
SPATS2L spermatogenesis associated, serine-rich 2-like
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRCIN1 SRC kinase signaling inhibitor 1
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAR steroidogenic acute regulatory protein
STX3 syntaxin 3
SUFU suppressor of fused homolog (Drosophila)
SYNGR1 synaptogyrin 1
SYPL2 synaptophysin-like 2
SYT11 synaptotagmin XI
SYT2 synaptotagmin II
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TBCK TBC1 domain containing kinase
TCF12 transcription factor 12
TEX261 testis expressed 261
THEM6 thioesterase superfamily member 6
TLL1 tolloid-like 1
TMEM159 transmembrane protein 159
TMEM185A transmembrane protein 185A
TMEM201 transmembrane protein 201
TMEM54 transmembrane protein 54
TMEM63A transmembrane protein 63A
TMEM63B transmembrane protein 63B
TMEM72 transmembrane protein 72
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRH thyrotropin-releasing hormone
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSC22D1 TSC22 domain family, member 1
TSPAN12 tetraspanin 12
TSPAN33 tetraspanin 33
TTC39A tetratricopeptide repeat domain 39A
TYMSOS TYMS opposite strand
TYSND1 trypsin domain containing 1
UBAC2 UBA domain containing 2
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
UNC45A unc-45 homolog A (C. elegans)
USP22 ubiquitin specific peptidase 22
VCAM1 vascular cell adhesion molecule 1
VEGFB vascular endothelial growth factor B
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
XYLT2 xylosyltransferase II
ZBED3 zinc finger, BED-type containing 3
ZBTB12 zinc finger and BTB domain containing 12
ZC3H7B zinc finger CCCH-type containing 7B
ZCCHC11 zinc finger, CCHC domain containing 11
ZFAND3 zinc finger, AN1-type domain 3
ZFAT-AS1 ZFAT antisense RNA 1
ZNF106 zinc finger protein 106
ZNF687 zinc finger protein 687
ZNF768 zinc finger protein 768

low expression

Symbol Name
ARMC2 armadillo repeat containing 2
C9ORF85 chromosome 9 open reading frame 85
FRG1B FSHD region gene 1 family, member B
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TBP TATA box binding protein
ZNF879 zinc finger protein 879