Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5671-01A-11R-1541-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Kidney renal clear cell carcinoma_KIRC (The Cancer Genome Atlas)
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Genes

383 genes with high or low expression in Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5671-01A-11R-1541-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A2M alpha-2-macroglobulin
ABHD11-AS1 ABHD11 antisense RNA 1 (tail to tail)
ABI3 ABI family, member 3
ACE angiotensin I converting enzyme
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACTN1 actinin, alpha 1
ADAM12 ADAM metallopeptidase domain 12
ADAM15 ADAM metallopeptidase domain 15
ADAM23 ADAM metallopeptidase domain 23
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADGRE5 adhesion G protein-coupled receptor E5
AEBP1 AE binding protein 1
AFAP1 actin filament associated protein 1
ALK anaplastic lymphoma receptor tyrosine kinase
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
APLNR apelin receptor
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOBR apolipoprotein B receptor
APOE apolipoprotein E
ARHGAP23 Rho GTPase activating protein 23
ARL4C ADP-ribosylation factor-like 4C
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
AVEN apoptosis, caspase activation inhibitor
BAX BCL2-associated X protein
BCORL1 BCL6 corepressor-like 1
BMF Bcl2 modifying factor
BMP1 bone morphogenetic protein 1
C15ORF39 chromosome 15 open reading frame 39
C15ORF54 chromosome 15 open reading frame 54
C1ORF127 chromosome 1 open reading frame 127
C1QC complement component 1, q subcomponent, C chain
C1QTNF6 C1q and tumor necrosis factor related protein 6
C1R complement component 1, r subcomponent
C2ORF27A chromosome 2 open reading frame 27A
C5AR1 complement component 5a receptor 1
C5ORF52 chromosome 5 open reading frame 52
C7ORF26 chromosome 7 open reading frame 26
CALHM2 calcium homeostasis modulator 2
CAMK4 calcium/calmodulin-dependent protein kinase IV
CARD11 caspase recruitment domain family, member 11
CBX2 chromobox homolog 2
CCDC102A coiled-coil domain containing 102A
CCDC91 coiled-coil domain containing 91
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD163 CD163 molecule
CD180 CD180 molecule
CD226 CD226 molecule
CD276 CD276 molecule
CD28 CD28 molecule
CD4 CD4 molecule
CD40LG CD40 ligand
CD5 CD5 molecule
CD6 CD6 molecule
CD68 CD68 molecule
CD93 CD93 molecule
CD99 CD99 molecule
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5
CDH8 cadherin 8, type 2
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHRDL2 chordin-like 2
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CHSY3 chondroitin sulfate synthase 3
CIC capicua transcriptional repressor
CLSTN3 calsyntenin 3
CMIP c-Maf inducing protein
CMKLR1 chemerin chemokine-like receptor 1
COL13A1 collagen, type XIII, alpha 1
COL15A1 collagen, type XV, alpha 1
COL18A1 collagen, type XVIII, alpha 1
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
COL5A2 collagen, type V, alpha 2
COL5A3 collagen, type V, alpha 3
COL6A2 collagen, type VI, alpha 2
COL6A3 collagen, type VI, alpha 3
COL8A1 collagen, type VIII, alpha 1
COLGALT1 collagen beta(1-O)galactosyltransferase 1
CORIN corin, serine peptidase
CORO7 coronin 7
COTL1 coactosin-like F-actin binding protein 1
CPA4 carboxypeptidase A4
CRYBA4 crystallin, beta A4
CRYBB1 crystallin, beta B1
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSH2 chorionic somatomammotropin hormone 2
CTSZ cathepsin Z
CXCR4 chemokine (C-X-C motif) receptor 4
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYTL1 cytokine-like 1
DCHS1 dachsous cadherin-related 1
DDIT4 DNA-damage-inducible transcript 4
DHH desert hedgehog
DISC1 disrupted in schizophrenia 1
DKK2 dickkopf WNT signaling pathway inhibitor 2
DMBT1 deleted in malignant brain tumors 1
DNASE2 deoxyribonuclease II, lysosomal
DNASE2B deoxyribonuclease II beta
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPT dermatopontin
DSC3 desmocollin 3
DYTN dystrotelin
EDIL3 EGF-like repeats and discoidin I-like domains 3
EGFLAM EGF-like, fibronectin type III and laminin G domains
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EMILIN2 elastin microfibril interfacer 2
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
F2R coagulation factor II (thrombin) receptor
FAM110D family with sequence similarity 110, member D
FAM124B family with sequence similarity 124B
FAP fibroblast activation protein, alpha
FBLIM1 filamin binding LIM protein 1
FBLN2 fibulin 2
FBN1 fibrillin 1
FCHO1 FCH domain only 1
FERMT3 fermitin family member 3
FES FES proto-oncogene, tyrosine kinase
FHL3 four and a half LIM domains 3
FLT3LG fms-related tyrosine kinase 3 ligand
FMNL1 formin-like 1
FMO3 flavin containing monooxygenase 3
FN1 fibronectin 1
FNDC1 fibronectin type III domain containing 1
FNDC8 fibronectin type III domain containing 8
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOLR2 folate receptor 2 (fetal)
FPR3 formyl peptide receptor 3
FTL ferritin, light polypeptide
FUCA1 fucosidase, alpha-L- 1, tissue
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene)
GAL3ST4 galactose-3-O-sulfotransferase 4
GAS7 growth arrest-specific 7
GDF15 growth differentiation factor 15
GGN gametogenetin
GLI3 GLI family zinc finger 3
GM2A GM2 ganglioside activator
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GPR150 G protein-coupled receptor 150
GPR161 G protein-coupled receptor 161
GPR68 G protein-coupled receptor 68
GRAMD1A GRAM domain containing 1A
GRAP2 GRB2-related adaptor protein 2
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRN granulin
GSDMA gasdermin A
GUCA1C guanylate cyclase activator 1C
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
H2BFWT H2B histone family, member W, testis-specific
HCK HCK proto-oncogene, Src family tyrosine kinase
HEG1 heart development protein with EGF-like domains 1
HERC2P4 hect domain and RLD 2 pseudogene 4
HES1 hes family bHLH transcription factor 1
HHIPL1 HHIP-like 1
HIC1 hypermethylated in cancer 1
HLX H2.0-like homeobox
HMOX1 heme oxygenase 1
HOXC6 homeobox C6
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HSPA12B heat shock 70kD protein 12B
HSPG2 heparan sulfate proteoglycan 2
HYAL2 hyaluronoglucosaminidase 2
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4
IGSF6 immunoglobulin superfamily, member 6
IL27RA interleukin 27 receptor, alpha
IL7R interleukin 7 receptor
INSL3 insulin-like 3 (Leydig cell)
IRS1 insulin receptor substrate 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein
JAG2 jagged 2
JUNB jun B proto-oncogene
KALRN kalirin, RhoGEF kinase
KHSRP KH-type splicing regulatory protein
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIRREL kin of IRRE like (Drosophila)
KLHDC8A kelch domain containing 8A
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAT linker for activation of T cells
LATS2 large tumor suppressor kinase 2
LGALS9 lectin, galactoside-binding, soluble, 9
LGI4 leucine-rich repeat LGI family, member 4
LHX6 LIM homeobox 6
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LOC100130264 uncharacterized LOC100130264
LOC646999 akirin 1 pseudogene
LOC653786 otoancorin pseudogene
LOXL2 lysyl oxidase-like 2
LRP1 low density lipoprotein receptor-related protein 1
LRRC18 leucine rich repeat containing 18
LY6G6D lymphocyte antigen 6 complex, locus G6D
LY86 lymphocyte antigen 86
MAN2B1 mannosidase, alpha, class 2B, member 1
MAP1S microtubule-associated protein 1S
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAP7D1 MAP7 domain containing 1
MARK4 MAP/microtubule affinity-regulating kinase 4
MARVELD1 MARVEL domain containing 1
MCOLN1 mucolipin 1
MCTP1 multiple C2 domains, transmembrane 1
MEOX1 mesenchyme homeobox 1
MEP1A meprin A, alpha (PABA peptide hydrolase)
MEX3D mex-3 RNA binding family member D
MIER2 mesoderm induction early response 1, family member 2
MKL1 megakaryoblastic leukemia (translocation) 1
MMP2 matrix metallopeptidase 2
MN1 meningioma (disrupted in balanced translocation) 1
MOSPD3 motile sperm domain containing 3
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
MYH9 myosin, heavy chain 9, non-muscle
MYO1G myosin IG
MYO9B myosin IXB
NAGA N-acetylgalactosaminidase, alpha-
NBPF6 neuroblastoma breakpoint family, member 6
NCOR2 nuclear receptor corepressor 2
NCR3 natural cytotoxicity triggering receptor 3
NHSL2 NHS-like 2
NID1 nidogen 1
NLGN4Y neuroligin 4, Y-linked
NOD1 nucleotide-binding oligomerization domain containing 1
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH3 notch 3
NRP2 neuropilin 2
NRROS negative regulator of reactive oxygen species
NUAK1 NUAK family, SNF1-like kinase, 1
OLFM2 olfactomedin 2
OLFML2B olfactomedin-like 2B
OLFML3 olfactomedin-like 3
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive
OR10H5 olfactory receptor, family 10, subfamily H, member 5
OR5H1 olfactory receptor, family 5, subfamily H, member 1
OR6F1 olfactory receptor, family 6, subfamily F, member 1
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin
OSM oncostatin M
OTOA otoancorin
PCDH17 protocadherin 17
PCDHA13 protocadherin alpha 13
PCDHB6 protocadherin beta 6
PDCL3 phosducin-like 3
PIAS4 protein inhibitor of activated STAT, 4
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PKD2L1 polycystic kidney disease 2-like 1
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLBD2 phospholipase B domain containing 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLIN3 perilipin 3
PLK2 polo-like kinase 2
PLSCR3 phospholipid scramblase 3
PLXNC1 plexin C1
PLXND1 plexin D1
PMS2CL PMS2 C-terminal like pseudogene
POLR1D polymerase (RNA) I polypeptide D, 16kDa
POSTN periostin, osteoblast specific factor
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP1R18 protein phosphatase 1, regulatory subunit 18
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PRDM1 PR domain containing 1, with ZNF domain
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRR12 proline rich 12
PRR34 proline rich 34
PSAP prosaposin
PTCRA pre T-cell antigen receptor alpha
PTGFRN prostaglandin F2 receptor inhibitor
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
PVR poliovirus receptor
PXN paxillin
RAB32 RAB32, member RAS oncogene family
RAB3C RAB3C, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RARG retinoic acid receptor, gamma
RASA3 RAS p21 protein activator 3
RASA4 RAS p21 protein activator 4
RFPL1 ret finger protein-like 1
RGS19 regulator of G-protein signaling 19
RIN3 Ras and Rab interactor 3
RNASE10 ribonuclease, RNase A family, 10 (non-active)
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPE65 retinal pigment epithelium-specific protein 65kDa
RPRML reprimo-like
RPUSD1 RNA pseudouridylate synthase domain containing 1
RUNX2 runt-related transcription factor 2
RXFP3 relaxin/insulin-like family peptide receptor 3
SBNO2 strawberry notch homolog 2 (Drosophila)
SCG2 secretogranin II
SDC3 syndecan 3
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SEPN1 selenoprotein N, 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SH3BP1 SH3-domain binding protein 1
SHKBP1 SH3KBP1 binding protein 1
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene)
SIGLEC8 sialic acid binding Ig-like lectin 8
SIGLEC9 sialic acid binding Ig-like lectin 9
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMN1 survival of motor neuron 1, telomeric
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNORA61 small nucleolar RNA, H/ACA box 61
SNORD89 small nucleolar RNA, C/D box 89
SOCS3 suppressor of cytokine signaling 3
SORBS3 sorbin and SH3 domain containing 3
SOX17 SRY (sex determining region Y)-box 17
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPI1 Spi-1 proto-oncogene
SPNS1 spinster homolog 1 (Drosophila)
SPRED3 sprouty-related, EVH1 domain containing 3
SRRD SRR1 domain containing
SRY sex determining region Y
SSC5D scavenger receptor cysteine rich family, 5 domains
SSH1 slingshot protein phosphatase 1
SSTR4 somatostatin receptor 4
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STAR steroidogenic acute regulatory protein
STK10 serine/threonine kinase 10
SULF1 sulfatase 1
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1
SYT15 synaptotagmin XV
TBC1D10A TBC1 domain family, member 10A
TCF3 transcription factor 3
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THBS2 thrombospondin 2
THOC5 THO complex 5
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TLN1 talin 1
TMEM108 transmembrane protein 108
TMEM173 transmembrane protein 173
TMEM184B transmembrane protein 184B
TMEM255B transmembrane protein 255B
TMEM44 transmembrane protein 44
TPSAB1 tryptase alpha/beta 1
TPST2 tyrosylprotein sulfotransferase 2
TRAM2 translocation associated membrane protein 2
TREML4 triggering receptor expressed on myeloid cells-like 4
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TSC22D4 TSC22 domain family, member 4
TSHZ2 teashirt zinc finger homeobox 2
TWF2 twinfilin actin binding protein 2
USP10 ubiquitin specific peptidase 10
VEGFC vascular endothelial growth factor C
VWF von Willebrand factor
WDFY4 WDFY family member 4
WISP1 WNT1 inducible signaling pathway protein 1
WIZ widely interspaced zinc finger motifs
WNT1 wingless-type MMTV integration site family, member 1
XCR1 chemokine (C motif) receptor 1
ZBTB20 zinc finger and BTB domain containing 20
ZFHX4 zinc finger homeobox 4
ZIC4 Zic family member 4
ZNF282 zinc finger protein 282
ZNF469 zinc finger protein 469
ZSCAN5B zinc finger and SCAN domain containing 5B
ZYX zyxin

low expression

Symbol Name
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
LARP7 La ribonucleoprotein domain family, member 7