Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5174-01A-01R-1426-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Kidney renal clear cell carcinoma_KIRC (The Cancer Genome Atlas)
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Genes

391 genes with high or low expression in Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5174-01A-01R-1426-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAMP angio-associated, migratory cell protein
AARS2 alanyl-tRNA synthetase 2, mitochondrial
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABCC6P2 ATP-binding cassette, sub-family C, member 6 pseudogene 2
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACAA2 acetyl-CoA acyltransferase 2
ACAD9 acyl-CoA dehydrogenase family, member 9
ACADVL acyl-CoA dehydrogenase, very long chain
ACO2 aconitase 2, mitochondrial
ACOT7 acyl-CoA thioesterase 7
ACP2 acid phosphatase 2, lysosomal
ACSF3 acyl-CoA synthetase family member 3
ACTN4 actinin, alpha 4
AGA aspartylglucosaminidase
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AIG1 androgen-induced 1
AJAP1 adherens junctions associated protein 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
ALG3 ALG3, alpha-1,3- mannosyltransferase
ALOX5 arachidonate 5-lipoxygenase
ANGPTL3 angiopoietin-like 3
ANXA1 annexin A1
ANXA4 annexin A4
AP1M1 adaptor-related protein complex 1, mu 1 subunit
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARL8A ADP-ribosylation factor-like 8A
ARMC9 armadillo repeat containing 9
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ARSE arylsulfatase E (chondrodysplasia punctata 1)
ATG9A autophagy related 9A
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
ATP13A1 ATPase type 13A1
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
AUP1 ancient ubiquitous protein 1
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
BOK BCL2-related ovarian killer
BTBD2 BTB (POZ) domain containing 2
C16ORF71 chromosome 16 open reading frame 71
C1ORF74 chromosome 1 open reading frame 74
C21ORF59 chromosome 21 open reading frame 59
C2ORF47 chromosome 2 open reading frame 47
CA5BP1 carbonic anhydrase VB pseudogene 1
CALML4 calmodulin-like 4
CALR calreticulin
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
CBLN1 cerebellin 1 precursor
CBWD5 COBW domain containing 5
CD151 CD151 molecule (Raph blood group)
CD24 CD24 molecule
CDK20 cyclin-dependent kinase 20
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDRT15 CMT1A duplicated region transcript 15
CERS2 ceramide synthase 2
CHST13 carbohydrate (chondroitin 4) sulfotransferase 13
CIDEB cell death-inducing DFFA-like effector b
CIR1 corepressor interacting with RBPJ, 1
CISD2 CDGSH iron sulfur domain 2
CIT citron rho-interacting serine/threonine kinase
CLPTM1 cleft lip and palate associated transmembrane protein 1
CLRN3 clarin 3
CLSTN3 calsyntenin 3
CLUH clustered mitochondria (cluA/CLU1) homolog
CNGA4 cyclic nucleotide gated channel alpha 4
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COPS8 COP9 signalosome subunit 8
CPT2 carnitine palmitoyltransferase 2
CRAT carnitine O-acetyltransferase
CRYAB crystallin, alpha B
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CTSA cathepsin A
CTSL cathepsin L
CTTN cortactin
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYSLTR2 cysteinyl leukotriene receptor 2
DDRGK1 DDRGK domain containing 1
DDTL D-dopachrome tautomerase-like
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DERA deoxyribose-phosphate aldolase (putative)
DGCR2 DiGeorge syndrome critical region gene 2
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNPEP aspartyl aminopeptidase
DOK4 docking protein 4
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
DPCD deleted in primary ciliary dyskinesia homolog (mouse)
DPP3 dipeptidyl-peptidase 3
DPP9 dipeptidyl-peptidase 9
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNLL1 dynein, light chain, LC8-type 1
DYNLT1 dynein, light chain, Tctex-type 1
DYX1C1 dyslexia susceptibility 1 candidate 1
EBNA1BP2 EBNA1 binding protein 2
ECH1 enoyl CoA hydratase 1, peroxisomal
ECHDC3 enoyl CoA hydratase domain containing 3
EIF4E2 eukaryotic translation initiation factor 4E family member 2
EIF5B eukaryotic translation initiation factor 5B
ELAC2 elaC ribonuclease Z 2
ELOVL1 ELOVL fatty acid elongase 1
EMC7 ER membrane protein complex subunit 7
ENO1 enolase 1, (alpha)
ENOSF1 enolase superfamily member 1
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2
EPPK1 epiplakin 1
ERBB3 erb-b2 receptor tyrosine kinase 3
ERP29 endoplasmic reticulum protein 29
ETFDH electron-transferring-flavoprotein dehydrogenase
F5 coagulation factor V (proaccelerin, labile factor)
FABP3 fatty acid binding protein 3, muscle and heart
FAHD1 fumarylacetoacetate hydrolase domain containing 1
FAM118B family with sequence similarity 118, member B
FAM134A family with sequence similarity 134, member A
FAM86C1 family with sequence similarity 86, member C1
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FARSB phenylalanyl-tRNA synthetase, beta subunit
FASTKD2 FAST kinase domains 2
FHL1 four and a half LIM domains 1
FLII flightless I homolog (Drosophila)
FLOT2 flotillin 2
FOXP4 forkhead box P4
FTCD formimidoyltransferase cyclodeaminase
GAL3ST1 galactose-3-O-sulfotransferase 1
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GBA glucosidase, beta, acid
GFRA1 GDNF family receptor alpha 1
GGT1 gamma-glutamyltransferase 1
GGTLC1 gamma-glutamyltransferase light chain 1
GGTLC2 gamma-glutamyltransferase light chain 2
GIGYF2 GRB10 interacting GYF protein 2
GLB1L galactosidase, beta 1-like
GLOD5 glyoxalase domain containing 5
GLYAT glycine-N-acyltransferase
GMPPA GDP-mannose pyrophosphorylase A
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit
GORASP2 golgi reassembly stacking protein 2, 55kDa
GPI glucose-6-phosphate isomerase
GPR108 G protein-coupled receptor 108
GPR89B G protein-coupled receptor 89B
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GSK3A glycogen synthase kinase 3 alpha
GSS glutathione synthetase
GSTA1 glutathione S-transferase alpha 1
GTF2A1L general transcription factor IIA, 1-like
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
GTF3C6 general transcription factor IIIC, polypeptide 6, alpha 35kDa
GUCD1 guanylyl cyclase domain containing 1
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HDGF hepatoma-derived growth factor
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HGD homogentisate 1,2-dioxygenase
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HHLA2 HERV-H LTR-associating 2
HLA-A major histocompatibility complex, class I, A
HLA-C major histocompatibility complex, class I, C
HNF1B HNF1 homeobox B
HOXC12 homeobox C12
HPN hepsin
HPS1 Hermansky-Pudlak syndrome 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
HYPK huntingtin interacting protein K
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IGSF1 immunoglobulin superfamily, member 1
IL17RB interleukin 17 receptor B
IL32 interleukin 32
IRAK1 interleukin-1 receptor-associated kinase 1
ITM2B integral membrane protein 2B
JMJD8 jumonji domain containing 8
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIAA0408 KIAA0408
KLC4 kinesin light chain 4
KLHDC7A kelch domain containing 7A
L3MBTL2 l(3)mbt-like 2 (Drosophila)
LEMD2 LEM domain containing 2
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LINC00515 long intergenic non-protein coding RNA 515
LMAN2L lectin, mannose-binding 2-like
LNP1 leukemia NUP98 fusion partner 1
LOC100129034 uncharacterized LOC100129034
LOC90784 uncharacterized LOC90784
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LRRC27 leucine rich repeat containing 27
LRRC8D leucine rich repeat containing 8 family, member D
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LYG1 lysozyme G-like 1
LYPLA2P1 lysophospholipase II pseudogene 1
MARCO macrophage receptor with collagenous structure
MED25 mediator complex subunit 25
MEGF6 multiple EGF-like-domains 6
METTL8 methyltransferase like 8
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MGC16142 uncharacterized protein MGC16142
MGST1 microsomal glutathione S-transferase 1
MICU1 mitochondrial calcium uptake 1
MPDU1 mannose-P-dolichol utilization defect 1
MPPE1 metallophosphoesterase 1
MRPL2 mitochondrial ribosomal protein L2
MRPL37 mitochondrial ribosomal protein L37
MRPL44 mitochondrial ribosomal protein L44
MRPS2 mitochondrial ribosomal protein S2
MTCH2 mitochondrial carrier 2
MVP major vault protein
MYO1C myosin IC
MYOM3 myomesin 3
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NAT8 N-acetyltransferase 8 (GCN5-related, putative)
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)
NCF1 neutrophil cytosolic factor 1
NCL nucleolin
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
NF2 neurofibromin 2 (merlin)
NGEF neuronal guanine nucleotide exchange factor
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
NINJ1 ninjurin 1
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NIT2 nitrilase family, member 2
NPVF neuropeptide VF precursor
NQO2 NAD(P)H dehydrogenase, quinone 2
NUCB1 nucleobindin 1
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19
OCIAD2 OCIA domain containing 2
OR2A2 olfactory receptor, family 2, subfamily A, member 2
OR2AE1 olfactory receptor, family 2, subfamily AE, member 1
OR9Q2 olfactory receptor, family 9, subfamily Q, member 2
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative)
PBDC1 polysaccharide biosynthesis domain containing 1
PCDHB18P protocadherin beta 18 pseudogene
PCDHB5 protocadherin beta 5
PCDHGA10 protocadherin gamma subfamily A, 10
PDCL3 phosducin-like 3
PDLIM4 PDZ and LIM domain 4
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PDZK1IP1 PDZK1 interacting protein 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PEX14 peroxisomal biogenesis factor 14
PFKL phosphofructokinase, liver
PFKP phosphofructokinase, platelet
PGAM1 phosphoglycerate mutase 1 (brain)
PGAM4 phosphoglycerate mutase family member 4
PGLYRP4 peptidoglycan recognition protein 4
PGM1 phosphoglucomutase 1
PIAS4 protein inhibitor of activated STAT, 4
PKM pyruvate kinase, muscle
PKP4 plakophilin 4
PLIN2 perilipin 2
PLIN4 perilipin 4
PLXNB2 plexin B2
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PNPLA4 patatin-like phospholipase domain containing 4
POLR1C polymerase (RNA) I polypeptide C, 30kDa
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
POMT1 protein-O-mannosyltransferase 1
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSPC1 paraspeckle component 1
PTGR1 prostaglandin reductase 1
RAB17 RAB17, member RAS oncogene family
RAB36 RAB36, member RAS oncogene family
RAB41 RAB41, member RAS oncogene family
RAB8A RAB8A, member RAS oncogene family
RABIF RAB interacting factor
RBP4 retinol binding protein 4, plasma
REP15 RAB15 effector protein
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
REXO2 RNA exonuclease 2
RMDN3 regulator of microtubule dynamics 3
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RNF167 ring finger protein 167
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RNPEP arginyl aminopeptidase (aminopeptidase B)
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
ROGDI rogdi homolog (Drosophila)
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SAMM50 SAMM50 sorting and assembly machinery component
SAP18 Sin3A-associated protein, 18kDa
SARDH sarcosine dehydrogenase
SCAMP2 secretory carrier membrane protein 2
SDF4 stromal cell derived factor 4
SEC31A SEC31 homolog A (S. cerevisiae)
SH3BGRL2 SH3 domain binding glutamate-rich protein like 2
SIAH2 siah E3 ubiquitin protein ligase 2
SLC16A13 solute carrier family 16, member 13
SLC16A4 solute carrier family 16, member 4
SLC17A3 solute carrier family 17 (organic anion transporter), member 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC23A3 solute carrier family 23, member 3
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC25A34 solute carrier family 25, member 34
SLC25A41 solute carrier family 25, member 41
SLC25A42 solute carrier family 25, member 42
SLC35B1 solute carrier family 35, member B1
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC35F6 solute carrier family 35, member F6
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC44A3 solute carrier family 44, member 3
SLC45A3 solute carrier family 45, member 3
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNORA41 small nucleolar RNA, H/ACA box 41
SPATS2L spermatogenesis associated, serine-rich 2-like
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SRPR signal recognition particle receptor (docking protein)
SSB Sjogren syndrome antigen B (autoantigen La)
STAP2 signal transducing adaptor family member 2
STBD1 starch binding domain 1
STK16 serine/threonine kinase 16
STK25 serine/threonine kinase 25
STS steroid sulfatase (microsomal), isozyme S
STXBP2 syntaxin binding protein 2
SUMO1 small ubiquitin-like modifier 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCHP trichoplein, keratin filament binding
TECR trans-2,3-enoyl-CoA reductase
THAP4 THAP domain containing 4
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast)
TINAG tubulointerstitial nephritis antigen
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM139 transmembrane protein 139
TMEM177 transmembrane protein 177
TMEM200B transmembrane protein 200B
TMEM246 transmembrane protein 246
TMEM63B transmembrane protein 63B
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TP53I3 tumor protein p53 inducible protein 3
TPMT thiopurine S-methyltransferase
TPPP tubulin polymerization promoting protein
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRAP1 TNF receptor-associated protein 1
TRAPPC3 trafficking protein particle complex 3
TRIM14 tripartite motif containing 14
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TRUB2 TruB pseudouridine (psi) synthase family member 2
TSPAN1 tetraspanin 1
TSPAN18 tetraspanin 18
TSPAN4 tetraspanin 4
TST thiosulfate sulfurtransferase (rhodanese)
TTC38 tetratricopeptide repeat domain 38
TUBA4A tubulin, alpha 4a
TUBB6 tubulin, beta 6 class V
TUBG1 tubulin, gamma 1
TXN thioredoxin
TYMS thymidylate synthetase
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UBXN8 UBX domain protein 8
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
UGT3A1 UDP glycosyltransferase 3 family, polypeptide A1
USH1C Usher syndrome 1C (autosomal recessive, severe)
USP40 ubiquitin specific peptidase 40
VAV2 vav 2 guanine nucleotide exchange factor
VCAM1 vascular cell adhesion molecule 1
VNN1 vanin 1
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VSTM5 V-set and transmembrane domain containing 5
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
ZBED1 zinc finger, BED-type containing 1
ZDHHC12 zinc finger, DHHC-type containing 12
ZDHHC16 zinc finger, DHHC-type containing 16
ZFAT zinc finger and AT hook domain containing
ZNF142 zinc finger protein 142

low expression

Symbol Name
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
C10ORF88 chromosome 10 open reading frame 88
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
SPATS2 spermatogenesis associated, serine-rich 2